Publications by Dr. Hristo Georgiev


Amable L, Ferreira Martins LA, Pierre R, Do Cruseiro M, Chabab G, Sergé A, Kergaravat C, Delord M, Viret C, Jaubert J, Liu C, Karray S, Marie JC, Irla M, Georgiev H, Clave E, Toubert A, Lucas B, Klibi J, Benlagha K. Intrinsic factors and CD1d1 but not CD1d2 expression levels control invariant natural killer T cell subset differentiation. Nat Commun. 2023 Dec 1;14(1):7922. doi: 10.1038/s41467-023-43424-7. PMID: 38040679; PMCID: PMC10692182.

Yang, T., Barros-Martins, J., Wang, Z., Wencker, M., Zhang, J., Smout, J., Gambhir, P., Janssen, A., Schimrock, A., Georgiev, H., León-Lara, X., Weiss, S., Huehn, J., Prinz, I., Krueger, A., Foerster, R., Walzer, T., & Ravens, S. (2023). RORγt+ c-Maf+ Vγ4+ γδ T cells are generated in the adult thymus but do not reach the periphery. Cell reports, 42(10), 113230.

Bošnjak, B., Henze, E., Lueder, Y., Do, K. T. H., Rezalotfi, A., Čuvalo, B., Ritter, C., Schimrock, A., Willenzon, S., Georgiev, H., Fritz, L., Galla, M., Wagner, K., Messerle, M., & Förster, R. (2023). MCK2-mediated MCMV infection of macrophages and virus dissemination to the salivary gland depends on MHC class I molecules. Cell reports, 42(6), 112597.

Papadogianni, G., Ravens, I., Hassan, A., Flatley, A., Feederle, R., Bernhardt, G., & Georgiev, H. (2023). Establishment and Functional Characterization of Murine Monoclonal Antibodies Recognizing Neuritin. Antibodies (Basel, Switzerland), 12(2), 28.

Georgiev, H.; Chopp, L.B.; Hogquist, K.A. Ultrasound-Guided Intra-Thymic Cell Injection. In T-Cell Development: Methods and Protocols; Bosselut, R., Vacchio, M.S., Eds.; Springer US: New York, NY, 2023; pp. 283–292 ISBN 978-1-0716-2740-2.


Peng, C.; Huggins, M.A.; Wanhainen, K.M.; Knutson, T.P.; Lu, H.; Georgiev, H.; Mittelsteadt, K.L.; Jarjour, N.N.; Wang, H.; Hogquist, K.A.; et al. Engagement of the Costimulatory Molecule ICOS in Tissues Promotes Establishment of CD8+ Tissue-Resident Memory T Cells. Immunity 2022, 55, 98-114.e5, doi:10.1016/j.immuni.2021.11.017.

Georgiev, H.; Papadogianni, G.; Bernhardt, G. Identification of Follicular T Cells in the Gut. In T-Follicular Helper Cells: Methods and Protocols; Graca, L., Ed.; Springer US: New York, NY, 2022; pp. 85–95 ISBN 978-1-0716-1736-6.


Bošnjak, B.; Odak, I.; Barros-Martins, J.; Sandrock, I.; Hammerschmidt, S.I.; Permanyer, M.; Patzer, G.E.; Greorgiev, H.; Gutierrez Jauregui, R.; Tscherne, A.; et al. Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents. Front. Immunol. 2021, 12, 4757, doi:10.3389/fimmu.2021.772240.

Lee, S.T.; Georgiev, H.; Breed, E.R.; Ruscher, R.; Hogquist, K.A. MHC Class I on Murine Hematopoietic APC Selects Type A IEL Precursors in the Thymus. Eur. J. Immunol. 2021, 51, 1080–1088, doi:

Permanyer, M.; Bošnjak, B.; Glage, S.; Friedrichsen, M.; Floess, S.; Huehn, J.; Patzer, G.E.; Odak, I.; Eckert, N.; Zargari, R.; et al. Efficient IL-2R Signaling Differentially Affects the Stability, Function, and Composition of the Regulatory T-Cell Pool. Cell. Mol. Immunol. 2021, 18, 398–414, doi:10.1038/s41423-020-00599-z.

Georgiev, H.; Peng, C.; Huggins, M.A.; Jameson, S.C.; Hogquist, K.A. Classical MHC Expression by DP Thymocytes Impairs the Selection of Non-Classical MHC Restricted Innate-like T Cells. Nat. Commun. 2021, 12, 2308, doi:10.1038/s41467-021-22589-z.

Todorova, N.; Rangelov, M.; Bogoeva, V.; Stoyanova, V.; Yordanova, A.; Nikolova, G.; Georgiev, H.; Dimitrova, D.; Mohedin, S.; Stoyanova, K.; et al. Anti-Idiotype ScFv Localizes an Autoepitope in the Globular Domain of C1q. Int. J. Mol. Sci. 2021, 22, doi:10.3390/ijms22158288.

Papadogianni, G.; Ravens, I.; Hassan, A.; Dittrich-Breiholz, O.; Bernhardt, G.; Georgiev, H. The Impact of Stress on the Transcriptomic Signature of INKT1 Cells. Biochem. Biophys. Reports 2021, 28, 101163, doi:


Hogquist, K.; Georgiev, H. Recent Advances in INKT Cell Development. F1000Research 2020, 9, 127, doi:10.12688/f1000research.21378.1.

Papadogianni, G.; Ravens, I.; Dittrich-Breiholz, O.; Bernhardt, G.; Georgiev, H. Impact of Aging on the Phenotype of Invariant Natural Killer T Cells in Mouse Thymus. Front. Immunol. 2020, 11, 2851, doi:10.3389/fimmu.2020.575764.


Georgiev, H.; Ravens, I.; Papadogianni, G.; Bernhardt, G. Coming of Age: CD96 Emerges as Modulator of Immune Responses. Front. Immunol. 2018, 9, 1072, doi:10.3389/fimmu.2018.01072.

Georgiev, H.; Ravens, I.; Papadogianni, G.; Halle, S.; Malissen, B.; Loots, G.G.; Förster, R.; Bernhardt, G. Shared and Unique Features Distinguishing Follicular T Helper and Regulatory Cells of Peripheral Lymph Node and Peyer’s Patches. Front. Immunol. 2018, 9, 714, doi:10.3389/fimmu.2018.00714.

Georgiev, H.; Ravens, I.; Papadogianni, G.; Malissen, B.; Förster, R.; Bernhardt, G. Blocking the ART2.2/P2X7-System Is Essential to Avoid a Detrimental Bias in Functional CD4 T Cell Studies. Eur. J. Immunol. 2018, 48, 1078–1081, doi:10.1002/eji.201747420.


Blume, J.; zur Lage, S.; Witzlau, K.; Georgiev, H.; Weiss, S.; Łyszkiewicz, M.; Zi[ecedil ]tara, N.; Krueger, A. Overexpression of Vα14Jα18 TCR Promotes Development of INKT Cells in the Absence of MiR-181a/b-1. Immunol. Cell Biol. 2016, 94, 741–746, doi:10.1038/icb.2016.40.

Georgiev, H.; Ravens, I.; Benarafa, C.; Förster, R.; Bernhardt, G. Distinct Gene Expression Patterns Correlate with Developmental and Functional Traits of INKT Subsets. Nat. Commun. 2016, 7, 13116, doi:10.1038/ncomms13116.

Georgiev, H.; Ravens, I.; Shibuya, A.; Förster, R.; Bernhardt, G. CD155/CD226-Interaction Impacts on the Generation of Innate CD8(+) Thymocytes by Regulating INKT-Cell Differentiation. Eur. J. Immunol. 2016, 46, 993–1003, doi:10.1002/eji.201546073.


Georgiev, H.; Danisch, S.; Chambers, B.J.; Shibuya, A.; Förster, R.; Bernhardt, G. To the Editor: TIGIT versus CD226: Hegemony or Coexistence? Eur. J. Immunol. 2014, 44, 307–308, doi:10.1002/eji.201343925