ecific human induced pluripotent stem cells” Tamari Askurava from the AG Gruh „Influence of titin variants on myocardial function in a 3D disease model of Peripartum Cardiomyopathy using human induced [...] Zweigerdt “Blood-Generating Heart-Forming Organoids (BG-HFOs) recapitulate co-development of the human hematopoietic system and the embryonic heart” Laura von Schledorn from the AG Olmer “Development of
Research at the Department of Human Genetics Our scientific findings make an important contribution to the understanding of ultra-rare genetic diseases, the identification of risk factors for cancer and [...] valuable tool for advances in our field. Find out more about the research groups at the Department of Human Genetics!
mechanisms. The second part of this project deals with human γδ T cells. We and other could recently show by next generation sequencing of human γδ TCRs that the adult, but not neonatal, γδ TCR repertoires [...] factors might fine-tune the development, organ-specificity and functional adaptation of murine and human γδ T cells. Murine IL-17 producing Vγ6 and Vγ4 T cells develop within an embryonic thymus and are
strong inhibitory and weak stimulatory signals in human immune cells when they interact with porcine tissues. Transgenic (tg) pigs expressing the human (h) inhibitory ligand hPD-L1 (CD274) and pigs lacking [...] vitro studies showed that SLA class I-deficient and hPD-L1 tg cells are only partially protected from human immune responses. We expect that hPD-L1 positive/SLA class I negative cells generated by combining
s”. Support from Human Resources Management: The service agreements of MHH can be found in the organizational manual. The collective agreements can be found on the forms page of Human Resources Management [...] questions, please do not hesitate to contact the contact persons of Human Resources Management . A relative is in need of care - what now? The Human Resources family page offers an overview with information on [...] protection, parental leave and for a care case. You are welcome to contact your personal advisor at Human Resources Management with these and any other questions that arise when it comes to reconciling work
composition of sarcomeric proteins. Subcellular myofibrils can be obtained from human (e.g., biopsies), human-derived and non-human cardiac and skeletal small muscle samples (e.g., mouse, rat, rabbit, zebrafish [...] Contraction-relaxation function and mechano-chemical coupling of myofibrils Investigations of human, human pluripotent stem cell-derived cardiomyocytes and animal contractile models in non-pathologic and [...] Motorproteinen Characterization of cardiomyocytes from heart tissue and from human stem cells AG Dr. Sarah Konze Cardiomyocytes from human induced pluripotent stem cells as a cellular model for hypertrophic c
the network is establishing new tools and expertise for accelerating the development of advanced human induced pluripotent stem cell (iPSC)-based therapies. The project also aims for overcoming scientific [...] to initiate a first-in-man (FIM) clinical trial for the therapeutic administration of allogeneic, human leukocyte antigen (HLA)-homozygous iPSC-cardiomyocyte aggregates, for improving the function of damaged [...] technologies for allogenic cell therapy to the heart” will focus on overcoming general hurdles to human induced pluripotent stem cell (iPSC)-based therapies, with the particular focus on heart failure,
EU regulation no. 536/2014 (human medicine ) Thursday, 2025-27-11, 9:00 a.m. – 1:30 p.m. at CRC: Refresher for clinical trials according to EU regulation no. 536/2014 (human medicine) fee per participant [...] m. – 4:30 p.m. at CRC: Basic course for clinical trials according to EU regulation no. 536/2014 (human medicine) Tuesday, 2025-25-11 , 9:00 a.m. – 4:30 p.m. at CRC: Basic course for other clinical trials
hospitals in Germany, so it is especially valuable for research with human samples/human models. My current project works with human samples, so it is very important for me to have this research environment
does not always come easy, we are offering free access to Meditricks - especially for students of human medicine – from 1 October 2024. And this is how it works: Simply register online via Meditricks and [...] Numerous videos, mnemonics and other learning aids are available. Requirement: If you are studying human medicine at the MHH and have an AMBOSS access, you are already perfectly equipped. Where to find