and molecular analyses. Selected pathophysiological aspects are also investigated in translational animal models within the framework of collaborations. Two goals are paramount: the precise determination
scientific practise in his/her group and for the overall compliance with the rules. Therefore, an animated communication is needed within a research group, especially, the free and open discussion of scientific
Steffens S, Terracciano CM, Tocchetti CG, Vlasman P, Yeung KK, Zacchigna S, Zwaagman D, Thum T. Animal models and animal-free innovations for cardiovascular research: Current status and routes to be explored.
approach, in which we combine cell biological, immunological and genetic methods with the use of animal disease models. In our studies we also aim to develop innovative immune-based therapeutic strategies
coupling of myofibrils Investigations of human, human pluripotent stem cell-derived cardiomyocytes and animal contractile models in non-pathologic and pathologic conditions Forschungsschwerpunkt Contraction
complex mechanisms of human organogenesis in a dish , the HFO model can also be used for replacing animal studies in the process of drug discovery and development such as teratogenicity assessment or drug [...] screen to conduct trials on a number of drug candidates, which in turn could reduce the usage of animals in line with the 3R principles (Replacement, Reduction and Refinement). Collaborators on heart disease
group Research focus Mobility is an indispensable feature that determines survival and success in the animal world. Skeletal muscle- that allows this mobility- is an astounding organ constituting over 650 muscles
Rabea Hinkel, German Primate Centre, Leibniz Institute for Primate Research, Department of Laboratory Animal Science 10.05.2023 REBIRTH colloquium (1 pm s.t., online lecture) ‘Bioinstructive materials to study
see your child. Can I bring something for my child? Of course. Often the children receive stuffed animals, lucky charms or even a music box as a gift from their parents and relatives. Please take care to
Bara, C., Haverich, A., and Hilfiker, A. 2017. Six-Year-Old Sheep as a Clinically Relevant Large Animal Model for Aortic Valve Replacement Using Tissue-Engineered Grafts Based on Decellularized Allogenic [...] Kallenbach K, Sorrentino S, Mertsching H, Kostin S, Pethig K, Haverich Md A, Cebotari S: A Novel Small Animal Model for Accelerated Investigation of Tissue Engineered Aortic Valved Conduits. Tissue Eng Part