Tümmler studied biochemistry (1971-1976) and human medicine (1974-1981) and received his doctorates in the fields of physical chemistry and human genetics (Dr. rer. nat. (1979) and Dr. med. (1984). After [...] After a research stay at the Hospital for Sick Children in Toronto, he worked at the Institute for Biophysical Chemistry of the Hannover Medical School since 1983 and habilitated in 1991 in the field of [...] involved in the care of patients with cystic fibrosis. His scientific work focuses on research in genetics, molecular pathology, infectiology and clinic of cystic fibrosis, microbial metagenomics of the

publications also in leading journals such as Science, Nature, Nature Genetics, Plos Genetics, Lancet and the American Journal of Human Genetics. Prof. Illig has been one of the mostly cited researchers worldwide [...] iobanking-Genomics” in the Institute of Epidemiology Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, 1998 - 2001 PostDoc, Institute of Epidemiology, Helmholtz Zentrum [...] Muenchen, German Research Center for Environmental Health, Neuherberg 1996 - 1998 PostDoc, Institute of Mammalian Genetics, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg

Benjamin Nilsson-Payant, Institute of Experimental Virology, Twincore Academic Background: Infectious Diseases and One Health, Erasmus Yiyang Cai Research Topic: Discovery of human genetic signatures affecting [...] colorectal cancer (CAC) Supervisor: PD Dr. Matthias Lochner, Institute for Medical Microbiology and Hospital Epidemiology, MHH Academic Background: Institute of Biomedical Sciences, University of Sao Paulo Berislav [...] Characterizing anti HCMV immunity in an infection model of explanted human lungs Supervisor: Prof. Dr. Reinhold Förster, Institute of Immunology, MHH Academic Background: Biomedicine, MHH Abdulwahab Elsayed

key safety aspects, a genetic integrity pipeline will be generated for defining the most sensitive assays for rigorous assessment of cells’ genetic stability. Moreover, a genetic rescue tool in the form [...] with more than six million euros, of which the Medical School Hannover (MHH) is the coordinating institution. The international research team led by Dr. Robert Zweigerdt and Prof. Dr. Ulrich Martin from MHH [...] the network is establishing new tools and expertise for accelerating the development of advanced human induced pluripotent stem cell (iPSC)-based therapies. The project also aims for overcoming scientific

cleanroom conditions. This is done at the MHH at the Institute for Cell Therapeutics, in the Cellular Therapy Centre (CTC) department. But the institute offers more than manufacturing and quality control [...] time-lapse video. A look into the microscope, for example, shows whether human T cells such as CARs and TRUCKs, which have been genetically modified in the laboratory, actually recognize tumor cells better and [...] fight against the most severe diseases. In addition to stem cell transplantation, therapies using genetically modified cells have now also been approved in Europe as so-called advanced therapy medicinal products

publications also in leading journals such as Science, Nature, Nature Genetics, Plos Genetics, Lancet and the American Journal of Human Genetics. Education 2010 Adjunct professor at Ludwig Maximilians-University [...] at Helmholtz Zentrum München Reviewer (selected journals) Nature Genetics, American Journal of Human Genetics, Circulation, PLOS Genetics, Experimental Dermatology, Allergy, Clinical and Experimental Allergy [...] iobanking-Genomics” in the Institute of Epidemiology Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, 1998 - 2001 PostDoc, Institute of Epidemiology, Helmholtz Zentrum

from the human heart, especially concerning the beating rate. Compared to the human heart, the beating frequency is about 5-8 times higher in the rodent model. Thus, a functional integration of human CMs into [...] characterization of genetically enriched hiPSC derived CMs and transplantation in a preclinical non-human primate model. Development of GMP compliant processes for the reprogramming and genetic modification of [...] Cebotari, Martin; DPZ, ITEM): Transplantation of genetically enriched human iPSC (hiPSC) derived cardiomyocytes (CMs) in a preclinical model of heart repair (non-human primate) Subproject 2 (MHH: Köhl, Martin;

Department / Institute: Institute of Experimental Virology - TWINCORE In recent years, three genetically and biologically different corona viruses have been transmitted from animals to humans and have caused [...] against SARS-CoV-2. Development of human neutralizing monoclonal antibodies against SARS-CoV-2 Project leader: Prof. Dr. med. Thomas F. Schulz Department / Institute: Institute of Virology We want to generate [...] a SARS-CoV-2 vaccine Project leader: Prof. Dr. Reinhold Förster Department / Institute: Institute of Immunology The Institute of Immunology is testing a promising SARS-CoV-2 vaccine candidate in cooperation

zoonotic potential, they can also be transmitted to humans and cause liver inflammation. In Germany alone, up to 420.000 people become infected with genetically slightly different HEV strains every year, mostly [...] "To do this, we want to use a special gene scissor that only cuts the viral RNA genetic information, but leaves human RNA intact, which acts as a construction manual for certain proteins to convert the [...] Research, a joint facility of the MHH and the Helmholtz Centre for Infection Research, and the Institute of Virology at the MHH. One project is concerned with the identification and characterisation of

the research group "Systems Biology of Microbial Communities" at the Institute of Molecular Bacteriology of TWINCORE. Significant genetic differences between harmless and dangerous bacteria The team examined [...] Escherichia coli bacteria live in the intestines of humans and play an important role there for normal intestinal function as well as for a functioning immune system. These intestinal inhabitants do not [...] Marco Galardinis team has studied this in more detail and found that E. coli has a significant genetic variation that contributes to the transition between the harmless life in the intestine (commensalism)