mechanisms of vasculogenesis. In parallel, we are studying new vessel formation in human renal organoids. We have discovered that human macrophages strongly influence vascularization and endothelial differentiation [...] of renal tissue. The goal is to vascularize organoids and to produce functional kidney tissue from human stem cells. We use zebrafish embryos with genetic markers for renal cells, macrophages and endothelium
Montag J., Weber N., Kowalski K. , Mayer A.-K., Iorga B., Brunkhorst A., Zweigerdt R., Kraft T., Human pluripotent stem cell-derived cardiomyocytes mimic intercellular heterogeneity as pathomechanism in [...] Thiemann S., Schwanke K., Lingk A., Krumm U., Piep B., Martin U., Zweigerdt R., Brenner B., Kraft T., In human embryonic stem cell-derived cardiomyocytes twitsch kinetics, action potential parameters and MyH-mRNA [...] kinetics and action potential parameters are independent of expressed myosin heavy chain isoform in human embryonic stem cell-derived cardiomyocytes. 2019, Acta Physiol. 227 (S719):146 Burkart V., Beck J
well-educated engineers, scientists, and clinicians To advance regenerative medicine to repair the human body following injury or disease, there is a critical need for well-educated engineers, scientists [...] , and clinicians to work jointly to translate applied research to clinical treatments to improve human health. “MHH has built a unique environment to bring all these facets together. In particular knowledge
Electrophysiological and microscopic characterisation of single neurons in neurosurgical sections of the human neokortex Investigation of Brain-Body-Interactions Development of cell culture models for translational [...] https://doi.org/10.1523/JNEUROSCI.2226-22.2023 All-trans retinoic acid induces synaptic plasticity in human cortical neurons.Lenz, M., Kruse, P., Eichler, A., Straehle, J., Beck, J., Deller, T., & Vlachos,
10.7554/eLife.64881. Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV. Theobald SJ, Kreer [...] (collaboration) Polymerization of misfolded Z alpha-1 antitrypsin protein lowers CX3CR1 expression in human PBMCs. Tumpara S, Ballmaier M, Wrenger S, König M, Lehmann M, Lichtinghagen R, Martinez-Delgado B [...] 2014 Nov;44(11):3368-79. doi: 10.1002/eji.201444515. Epub 2014 Sep 19. PMID: 25100508 Activated human hepatic stellate cells induce myeloid derived suppressor cells from peripheral blood monocytes in
the dynamics of infection and immune cells with and against HCMV in an infection model of explanted human lungs. Kim Do Thi Hoang DoThiHoang.Kim @ mh-hannover.de Phone: +49 511 532 9738 Kim is part of the [...] de Phone: +49 511 532 9731 Rodrigo is focusing on characterization of the immune response of both humans and mice to prominent pathogens. His main area of expertise is spectra-flow cytometry. Dr. Swantje [...] on developing a reporter system to monitor early events of antigen-dependent T cell activation in humans. She is particularly interested in T cells and their behavior within various immune-related contexts
Vorstand der „Young Investigators“ der Gesellschaft für Pädiatrische Pneumologie (GPP)“. studied human medicine in Leipzig, Munich, Sydney, Mendoza and Amsterdam. Since 2006, her pediatric training took [...] Journal of Respiratory and Critical Care Medicine. After her medical doctoral thesis in the field of human genetics, she received her PhD in molecular medicine in 2014 (Hannover Biomedical Research School
Vorstand der „Young Investigators“ der Gesellschaft für Pädiatrische Pneumologie (GPP)“. studied human medicine in Leipzig, Munich, Sydney, Mendoza and Amsterdam. Since 2006, her pediatric training took [...] Journal of Respiratory and Critical Care Medicine. After her medical doctoral thesis in the field of human genetics, she received her PhD in molecular medicine in 2014 (Hannover Biomedical Research School
Biochemistry and Methods (BCB P 15) Master of Science Biochemistry: Instrumental techniques (BCM WP 41) Human Medicine and Dentistry: Biochemistry/Molecular Biology
Martin - in collaboration with a group from Zürich - artificially introduced an ion channel into human iPS cells. Physiological occurrence of this ion channel is restricted to the thyroid and the stomach [...] Hoerstrup S, Luescher TF, Kaufmann PA, Landmesser U*, Martin U*: Transplantation and tracking of human-induced pluripotent stem cells in a pig model of myocardial infarction: assessment of cell survival