airway microbiology, electrophysiology and genetics in patients with CF (see publications ). Through our many years of clinical work with CF patients, we have long-term histories and biomaterial collections [...] pathways triggered by them could represent promising targets for new therapeutic approaches in CF patients, for example. Innate lymphoid cells (ILCs) localized in the airway mucosa play a critical role in [...] we are investigating the composition, phenotype and function of ILCs in lung tissue from human CF patients and in a mouse model of CF-like disease (bENaC mice) using advanced deep phenotyping methods such

clinical and epidemiological methods to further improve early diagnosis and quality-based treatment of patients with acute kidney or kidney transplant disease. We pay special attention to the exploitation, c [...] goal is to use the knowledge gained to improve prediction, clinical classification, and therapy in patients* with kidney disease. Cooperation partners Institut für Sozialmedizin, Gesundheitssystemforschung [...] ChAd/BNT compared with homologous BNT/BNT and ChAd/ChAd SARS-CoV-2 vaccination in hemodialysis patients: A multicenter prospective observational study. Journal of Nephrology, 35,1467-1478, 2022. Haarhaus

myopathies including cancer cachexia, prevalent in nearly 80% of cancer patients with reported mortality rate in more than 30% patients. The major focus of our group is understand how SUMO (Small Ubiquitin-like [...] extent of functional changes caused by HCM mutations in cardiomyocytes of affected heterozygous patients is very different among cardiomyocytes isolated from the same tissue. For example, some cardiomyocytes [...] show for β-cardiac myosin heavy chain (β-MyHC) and cardiac troponin I (cTnI) that in each of the patients studied, individual cardiomyocytes from the same tissue express very different proportions of mutated

a tubular heart prosthesis. As a single-chamber heart implant, the organ replacement could help patients with congenital heart defects who are hereditary without a heart chamber. A healthy heart has two [...] there is only one ventricle from birth, it supplies both the body and the pulmonary artery. "These patients have mixed blood in their hearts and have to undergo multiple operations in childhood so that the

immediately. Do not publish personal data or telephone numbers. Photos and videos (especially of patients) should not be distributed without consideration: Please respect copyright and data protection laws [...] advice or appointments cannot be given through our social media channels. It is best to contact the Patient Service Center (German). Applications and corresponding documents will not be processed via social

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in advanced organ failure and thus improve patient care. Current therapies are symptomatic, and the lack of donor organs places an additional burden on patients and their families. R-CUBE will develop multimodal [...] know the patients' situation very well, and the researchers, who are investigating the fundamentals in order to enable better prevention, diagnosis and treatment. In order to be able to help patients, basic [...] regeneration and repair and offer novel strategies for organ replacement. As world-leading center for patients with organ diseases, the transplantation spectrum of MHH ranges from abdominal and thoracic organs

pursuing the goal that their approach should offer in future an alternative, personalized therapy for patients who are currently dependent on a left ventricular assist system (LVAD) as a “bridge to-repair” strategy [...] GmbH (LV) . The project is granted a total of more than one and half million euros. Background For patients with heart failure as a result of ischemic cardiomyopathy (ICM) after myocardial infarction (MI) [...] of the application of multicellular cardiac muscle cell aggregates up to clinical application in patients with chronic heart failure after myocardial infarction. In a preclinical subacute myocardial infarction

in the BMBF-funded Network of University Medicine Network of University Medicine (NUM) Providing patients with optimal care, prevention infections and expanding healthcare is the mission statement of the [...] placed on hospital-related research and health care research. the results of which directly benefit patients, are incorporated into crisis management and contribute to the establishment of a sustainable, national

infections. With the help of the developed test, it will be possible to examine a large number of patients in clinical studies and determine how long these essential antibodies are present in the blood. [...] directly transferred on COVID-19 samples. Besides preparation of multiblock samples from different patients for quick and cost-efficient analysis of a larger cohort of samples and a large portfolio of established [...] emerging conflicts over decisions and values are assessed. About 2000 physicians, nursing staff and patients from all over Germany will be surveyed by specific questionnaires. Based on our findings, a com