Lühmann GERMANY Luehmann.Jonathan @ mh-hannover.de Supervisor: Prof. Dr. Doris Steinemann (Human Genetics) Project: Optical Mapping to detect structural genomic variants in cancer Jonathan was class speaker [...] / Prof. Dr. Axel Schambach (Experimental Hematology) Project: Improving AAV vectors by capsid engineering for gene therapy of inner ear disorders Final exam November 2024 Philip Mausberg GERMANY Mausberg [...] Philip @ mh-hannover.de Supervisor: Prof. Dr. Britta Eiz-Vesper (Transfusionmedicine) Project: Gene engineered specific cells for personalized adoptive immunotherapy Final exam June 2024 Gema Morillas Ramos
key safety aspects, a genetic integrity pipeline will be generated for defining the most sensitive assays for rigorous assessment of cells’ genetic stability. Moreover, a genetic rescue tool in the form [...] academic, clinical and industrial partners in the field of iPSC technology, bioprocessing, genomic engineering, analysis and safety, immunology and clinical translation. The project is coordinated by Dr. Robert [...] te aggregate production WP 2: Immunogenicity of HLA homozygous iPS-cardiomyocytes WP 3: Safety, genetic integrity, and suicide gene technologies WP 4: Regulations and Advanced Therapy Medicinal Product
cells for tissue engineering approaches. J Tissue Eng 8:2041731417698852. Mogaldea, A., Goecke, T., Theodoridis, K., Haverich, A., Cebotari, S., and Hilfiker, A. 2017. Tissue Engineering of Vein Valves Based [...] A, Haverich A: Biological scaffolds for heart valve tissue engineering. In: Hauser, Hansjörg; Fussenegger, Martin M Editors. Tissue Engineering, Series: Methods in Molecular Medicine. 2nd ed. New York: [...] application of tissue engineered human heart valves using autologous progenitor cells. Circulation 2006;114, no. 1 Suppl:I132. Giere B, Hilfiker A, Haverich A: Tissue engineering -- in vitro culture of
N., American journal of respiratory and critical care medicine, 2014. 189: 167), efficient genetic engineering of iPSCs (Merkert, S., Stem cell reports, 2014. 2: 107) as well as the development of technologies [...] characterization of genetically enriched hiPSC derived CMs and transplantation in a preclinical non-human primate model. Development of GMP compliant processes for the reprogramming and genetic modification of [...] Subproject 2 (MHH: Köhl, Martin; Miltenyi): GMP compliant scale up of iPSC-generation and genetic engineering Subproject 3 (MHH: Köhl, Zweigerdt; Miltenyi): Clinical scale up of iPSC-CM and MSC production
inflammation or injury. For 30 years, A1AT is used as a substitution therapy for emphysema patients with genetic A1AT deficiency, and shows very good safety and tolerance in many preclinical models. Current scientific [...] Dr. Rainer Blasczyk Department / Institute: Institute of Transfusion Medicine and Transplant Engineering COVID-19 convalescent plasma (CCP) donated by recovered patients is a promising treatment option
cell source, both in terms of basic science and in their application in biomedical research and engineering. The work of my group is intended to help identify the importance of these cells for the areas [...] students. Signaling pathways in regeneration: A molecular mechanism for tendon cell formation. Genetically modified MSCs differentiated in vitro into tendon-like cells. Implantation in vivo enabled cel [...] as an alternative to current biotherapies. Contributions to the MHH research focus "Biomedical Engineering, Implants" Graded implants. Biomedical implant research has so far concentrated on implants for
Thomas Thum (Institute of Molecular and Translational Therapeutic Strategies, IMTTS) Project: Engineering AAV in vivo tropism towards pre-apoptotic cardiomyocytes Shubham is class speaker! Lily Sophie [...] Sophie Rose , GERMANY, Rose.Lily@mh-hannover.de Supervisor: Prof. Dr. Ruthhild Weber (Human Genetics) Project: Ribosomal biogenesis genes and predisposition to brain tumors Tirthankar Saha , INDIA, Saha.Tir
CRISPR/Cas9 technology for precise genome editing in order to be able to correct disease-specific genetic mutations in a targeted manner. With regard to the public debate on the use of pluripotent (embryonic) [...] Pluripotent Stem Cell-Derived Hepatobiliary Organoids for Studies of Disease Mechanisms and Gene Engineering Approaches (Funding: REBIRTH - MWK Lower Saxony) iPS-based liver models and CRISPR/Cas-edited controls
for regenerative therapies were tested using novel (preferably postnatal) cell sources modified by genetic, epigenetic or matrix-based principles. HBRS - since 2000 Founded in 2000, the interdisciplinary [...] established research foci "Infection & Immunity", "Transplantation & Regeneration" and "Biomedical Engineering & Implants" as well as the new area of potential "Oncology". In the Excellence Initiative funding
after kidney transplant Further infomation: https://ntx360grad.de/ Copyright: NTX 360° Human genetics Human genetic studies Information will follow Lung Tx Lung-Tx For patients with the most severe end-stage [...] the development of novel tools for correction of genetic mutations in patient-specific stem cells and their use in disease modelling and tissue engineering. Based on our philosophy of creating synergies [...] clinicians and biomedical researchers with physical and chemical scientists and engineers, the fields of materials engineering, chemistry and physics have complemented our biomedical discoveries by developing