Lühmann GERMANY Luehmann.Jonathan @ mh-hannover.de Supervisor: Prof. Dr. Doris Steinemann (Human Genetics) Project: Optical Mapping to detect structural genomic variants in cancer Jonathan was class speaker [...] / Prof. Dr. Axel Schambach (Experimental Hematology) Project: Improving AAV vectors by capsid engineering for gene therapy of inner ear disorders Final exam November 2024 Philip Mausberg GERMANY Mausberg [...] Philip @ mh-hannover.de Supervisor: Prof. Dr. Britta Eiz-Vesper (Transfusionmedicine) Project: Gene engineered specific cells for personalized adoptive immunotherapy Final exam June 2024 Gema Morillas Ramos
key safety aspects, a genetic integrity pipeline will be generated for defining the most sensitive assays for rigorous assessment of cells’ genetic stability. Moreover, a genetic rescue tool in the form [...] academic, clinical and industrial partners in the field of iPSC technology, bioprocessing, genomic engineering, analysis and safety, immunology and clinical translation. The project is coordinated by Dr. Robert [...] te aggregate production WP 2: Immunogenicity of HLA homozygous iPS-cardiomyocytes WP 3: Safety, genetic integrity, and suicide gene technologies WP 4: Regulations and Advanced Therapy Medicinal Product
group of Prof. Dr. Britta Eiz-Vesper at the Institute of Transfusion Medicine and Transplant Engineering at Hannover Medical School. Her scientific interest lies within the field of cellular immunotherapy [...] immunotherapy, with a particular focus on naturally occurring antiviral T cells as well as genetically modified T cells (chimeric antigen receptors, recombinant T cell receptors, CRISPR/Cas9). The aim is to optimize
cells for tissue engineering approaches. J Tissue Eng 8:2041731417698852. Mogaldea, A., Goecke, T., Theodoridis, K., Haverich, A., Cebotari, S., and Hilfiker, A. 2017. Tissue Engineering of Vein Valves Based [...] A, Haverich A: Biological scaffolds for heart valve tissue engineering. In: Hauser, Hansjörg; Fussenegger, Martin M Editors. Tissue Engineering, Series: Methods in Molecular Medicine. 2nd ed. New York: [...] application of tissue engineered human heart valves using autologous progenitor cells. Circulation 2006;114, no. 1 Suppl:I132. Giere B, Hilfiker A, Haverich A: Tissue engineering -- in vitro culture of
N., American journal of respiratory and critical care medicine, 2014. 189: 167), efficient genetic engineering of iPSCs (Merkert, S., Stem cell reports, 2014. 2: 107) as well as the development of technologies [...] characterization of genetically enriched hiPSC derived CMs and transplantation in a preclinical non-human primate model. Development of GMP compliant processes for the reprogramming and genetic modification of [...] Subproject 2 (MHH: Köhl, Martin; Miltenyi): GMP compliant scale up of iPSC-generation and genetic engineering Subproject 3 (MHH: Köhl, Zweigerdt; Miltenyi): Clinical scale up of iPSC-CM and MSC production
inflammation or injury. For 30 years, A1AT is used as a substitution therapy for emphysema patients with genetic A1AT deficiency, and shows very good safety and tolerance in many preclinical models. Current scientific [...] Dr. Rainer Blasczyk Department / Institute: Institute of Transfusion Medicine and Transplant Engineering COVID-19 convalescent plasma (CCP) donated by recovered patients is a promising treatment option
Evaluation of a Novel Hyaluronic Acid–Laminin Hydrogel as Luminal Filler and Carrier System for Genetically Engineered Schwann Cells in Critical Gap Length Tubular Peripheral Nerve Graft in Rats. Dietzmeyer N
Thomas Thum (Institute of Molecular and Translational Therapeutic Strategies, IMTTS) Project: Engineering AAV in vivo tropism towards pre-apoptotic cardiomyocytes Shubham is class speaker! Lily Sophie [...] Sophie Rose , GERMANY, Rose.Lily@mh-hannover.de Supervisor: Prof. Dr. Ruthhild Weber (Human Genetics) Project: Ribosomal biogenesis genes and predisposition to brain tumors Tirthankar Saha , INDIA, Saha.Tir
Evaluation of a Novel Hyaluronic Acid–Laminin Hydrogel as Luminal Filler and Carrier System for Genetically Engineered Schwann Cells in Critical Gap Length Tubular Peripheral Nerve Graft in Rats. Dietzmeyer N [...] Haastert-Talini K (2014): In vitro cell-seeded chitosan filma for peripheral nerve tissue engineering. Tissue Engineering Part A; 20(17-18):2339-49. doi: 10.1089/ten.TEA.2013.0621. http://www.ncbi.nlm.nih.g [...] pathway via profilin. Hum Mol Genet. 2011 Dec 15;20(24):4865-78. Epub 2011 Sep 14. Kirsten Haastert-Talini (2011) Chapter 9: Experimental Approaches on Tissue engineering Repair of Peripheral Nerve Gaps
for regenerative therapies were tested using novel (preferably postnatal) cell sources modified by genetic, epigenetic or matrix-based principles. HBRS - since 2000 Founded in 2000, the interdisciplinary [...] established research foci "Infection & Immunity", "Transplantation & Regeneration" and "Biomedical Engineering & Implants" as well as the new area of potential "Oncology". In the Excellence Initiative funding