Steffens S, Terracciano CM, Tocchetti CG, Vlasman P, Yeung KK, Zacchigna S, Zwaagman D, Thum T. Animal models and animal-free innovations for cardiovascular research: Current status and routes to be explored.

coupling of myofibrils Investigations of human, human pluripotent stem cell-derived cardiomyocytes and animal contractile models in non-pathologic and pathologic conditions Forschungsschwerpunkt Contraction

group Research focus Mobility is an indispensable feature that determines survival and success in the animal world. Skeletal muscle- that allows this mobility- is an astounding organ constituting over 650 muscles

complex mechanisms of human organogenesis in a dish , the HFO model can also be used for replacing animal studies in the process of drug discovery and development such as teratogenicity assessment or drug [...] screen to conduct trials on a number of drug candidates, which in turn could reduce the usage of animals in line with the 3R principles (Replacement, Reduction and Refinement). Collaborators on heart disease

see your child. Can I bring something for my child? Of course. Often the children receive stuffed animals, lucky charms or even a music box as a gift from their parents and relatives. Please take care to

Rabea Hinkel, German Primate Centre, Leibniz Institute for Primate Research, Department of Laboratory Animal Science 10.05.2023 REBIRTH colloquium (1 pm s.t., online lecture) ‘Bioinstructive materials to study

Experimental applications and clinical use of adult stem cells" (lecture series) "Introduction to animal cell culture technology" (internship at NIFE) Teaching award 2021 for Prof. Dr. Andrea Hoffmann Contact

Bara, C., Haverich, A., and Hilfiker, A. 2017. Six-Year-Old Sheep as a Clinically Relevant Large Animal Model for Aortic Valve Replacement Using Tissue-Engineered Grafts Based on Decellularized Allogenic [...] Kallenbach K, Sorrentino S, Mertsching H, Kostin S, Pethig K, Haverich Md A, Cebotari S: A Novel Small Animal Model for Accelerated Investigation of Tissue Engineered Aortic Valved Conduits. Tissue Eng Part

Cardiovasc Res. 2019. https://www.ncbi.nlm.nih.gov/pubmed/31711127 Riehle C, Bauersachs J. Small animal models of heart failure. Cardiovasc Res. 2019;115:1838-1849. https://www.ncbi.nlm.nih.gov/pubmed/31243437

Laugwitz KL, Moretti A, Klymiuk N, Thum T, Kupatt C. AntimiR-132 attenuates myocardial hypertrophy in an animal model of percutaneous aortic constriction. J Am Coll Cardiol. 2021;77:2923-2935. https://pubmed.ncbi