Diseases and Endocrinology 05.12.2023 REBIRTH Special Lecture (4:15 p.m., lecture hall O) ‘The multidirectionality of life’ Dr. Miguel A. Esteban, BGI-Research, Hangzhou / Shenzhen 22.11.2023 REBIRTH colloquium [...] who have been invited to present their research. There is typically one report on a clinical topic and one report on a research topic. Past events iPS Based Cell Therapies - From Bench to Bedside 03. - [...] invited external lecturers take place within the scope of the colloquium. The colloquium serves as a discussion forum of 'REBIRTH' and is not only supposed to promote the initiation of external cooperations

understanding of the underlying processes and translate this into a therapeutic concept that combines elements of virotherapy and immunotherapy in a clinically applicable approach. Research projects Generation [...] of staff and our publications. The use of viruses that preferentially replicate in tumor tissue is a promising new strategy for the treatment of solid tumors. The effect of "oncolytic virotherapy" is based [...] that the virus only replicates in cells that exhibit genetic changes characteristic of tumors, such as p53 dysfunction or telomerase activation. We have already been able to develop several prototypes of oncolytic

S, Kopp J, Rovai A, Varnholt D, Wachs AS, Goyenvalle A, Aarstma-Rus A, Ott M, Tiede A, Langemeier J, Bohne J. Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant [...] 8690. 3. Krooss SA, Dai Z, Schmidt F, Rovai A, Fakhiri J, Dhingra A, Yuan Q, Yang T, Balakrishnan A, Steinbrück L, Srivaratharajan S, Manns MP, Schambach A, Grimm D, Bohne J , Sharma AD, Büning H, Ott [...] interested in non-coding mutations causing various human diseases. Both areas follow our central idea: A deeper knowledge of both viral gene expression and the pathomechanisms of non-coding mutations will

and gene expression of Chlamydia trachomatis during persistent infection. A study to establish new therapeutic pathways and a better understanding of the pathogenesis of reactive arthritis Final exam November [...] Risk Factors in Mantle Cell Lymphomas Further delineation of tumor suppressor regions on chromosome 1 p22 Final exam November 12th, 2004. Christian Bernreuther GERMANY (Dr. med.) supervisor: Prof. Dr. Grothe [...] n Surgery project: Transdifferentiation and proliferation of hematopoetic stem cells in the liver; a CD45 diallelic model in rats Final exam November 12th, 2004 Meta Djojosubroto INDONESIA supervisor:

trapping and disposal by neutrophils. Noack A, Gericke B, von Köckritz-Blickwede M, Menze A, Noack S, Gerhauser I, Osten F , Naim HY, Löscher W. Proc Natl Acad Sci U.S.A.; 2018 Oct 08; 115 (41) E9590-E9599. doi: [...] yjmcc.2024.11.007 ; PubMed 2023 Human brain microvascular endothelial cells release different types of P-glycoprotein-containing extracellular vesicles upon exposure to doxorubicin, Osten F , Löscher W, Gericke [...] tes, Osten, F ., Weber, N., Wendland, M., Holler, T., Piep, B., Kröhn, S., Teske, J., Bodenschatz, A.K., Devadas, S.B., Menge, K.S., Chatterjee, S., Schwanke, K., Kosanke, M., Montag, J., Thum, T., Zweigerdt

Sugianto RI, Memaran N, Schmidt BMW, Doyon A, Thurn-Valsassina D, Alpay H, Anarat A, Arbeiter K, Azukaitis K, Bayazit AK, Bulut IK, Caliskan S, Canpolat N, Duzova A, Gellerman J, Harambat J, Homeyer D, Litwin [...] tomography: a systematic review and meta-analysis of 21 propensity score-matched cohort studies. Eur Radiol. 2022. doi: 10.1007/s00330-022-08916-y Eden G*, Schmidt JJ*, Büttner S, Kümpers P, Hafer C, Rovas [...] *Authors contributed equally. Vollmer Barbosa C, Lang H, Melk A, Schmidt BMW. Renal events in patients receiving Neprilysin inhibitors: a systematic review and meta-analysis. Nephrol Dial Transplant. 2022

analysis reveals that regulatory light chains fine-tune skeletal myosin-II function , Nayak A, Wang T , Franz P, Steffen W, Chizhov I, Tsiavaliaris G, Amrute-Nayak M, J Biol Chem. 2020 Apr 9. pii: jbc.RA120 [...] Load-Dependent Actomyosin Dissociation Kinetics for Cardiac and Slow Skeletal Myosin, Wang T, Nayak A, Kraft T, Amrute-Nayak M., Nano Micro Small. 2024 Oct 7:e2406865.doi: 10.1002/smll.202406865. Online [...] Acto-Myosin Cross-Bridge Stiffness Depends on the Nucleotide State of Myosin II . Wang T, Brenner B, Nayak A, and Amrute-Nayak M . Nano Letters, 2020 Sep 15. doi: 10.1021/acs.nanolett.0c02960. [Online ahead of

J, Franke A, Schwanke K, Göhring G, Kraft T, Francino A, Zweigerdt R, Martin U. Generation of two iPSC clones (MHHi021-A and MHHi021-B) from a patient with hypertrophic cardiomyopathy with p.Arg723Gly [...] Viereck J, Kumarswamy R, Foinquinos A, Xiao K, Avramopoulos P, Kunz M, Dittrich M, Maetzig T, Zimmer K, Remke J, Just A, Fendrich J, Scherf K, Bolesani E, Schambach A, Weidemann F, Zweigerdt R, de Windt [...] doi: 10.1016/j.scr.2018.07.025. Epub 2018 Aug 18. PMID: 30145492. Koch L, Deiwick A, Franke A, Schwanke K, Haverich A, Zweigerdt R, Chichkov B.Laser bioprinting of human induced pluripotent stem cells-the

Klein, Pediatric Hematology and Oncology, OE 6780, project: The role of the cellular adaptor protein p14 in hematopoiesis and leukemia. Final exam November 2014 Jayendra Kumar Krishnaswamy INDIA supervisor: [...] INDIA supervisor: Dr. Dittrich, SFB 587, OE 9431, project: Polysensitization & skin lung interplay in a mouse model of allergic skin inflammation Final exam November 2012 Ankita Minhas INDIA supervisor: Prof [...] Müller) GERMANY supervisor: Dr. Martin, LEBAO, OE 6217, project: Identification of cardiogenic factors in a Rhesus monkey embryonic stem cell model Final exam November 2012 Mudita Pincha INDIA supervisor: PD

metabolism: characterization of individual genetic variation of UDP-glucuronosyltransferase regulation in a mouse model Final exam November 2009 Luis Guachalla Gutierrez BOLIVIA supervisor: Prof. Dr. Rudolph [...] Dr. Greten, Gastroenterology/Hepatology/ Endocrinology, OE 6810, project: T cell based therapies in a mouse model of colitis associated colon cancer Final exam November 2009 Harshvardhan Rolyan INDIA s [...] Giessen project: Analysis of the mechanisms by which the yersinia enterocolitica virulence factor Yop.P inhibits host cell protein kinases Final exam June 2009 Katja Zscheppang GERMANY supervisor: Dr. Dammann