focus is on inflammatory changes in bronchial asthma and cystic fibrosis. In both diseases, the patient's immune response plays a central role in disease progression. The overall goal of our projects is [...] targets for preventive measures for these diseases. By studying in vitro models, mouse models, and patient material we identify and characterize the immunological-inflammatory mechanisms that set central [...] cohort investigating bronchial asthma and principal investigator of several clinical trials for patients with cystic fibrosis. Furthermore, we are involved in the DFG-funded priority program 1937 "innate

care of patients to the economy and society. "In medicine in particular, it is essential that science and the healthcare sector work hand in hand. Only the transfer of research results into patient care opens [...] we start transferring knowledge, the greater the chance that good ideas will ultimately benefit patients," says Christiane Bock von Wülfingen, Head of FWT2. The new course for students from the 4th year

diseased or damaged tissue (e.g. heart valves, vessels, vascular valves) is performed with autologous (patient-own) cells seeded on a matrix. At present, laboratory research focuses on cell and development biology [...] will be "prefabricated" in vitro in a bioreactor. Subsequently, vital tissue will be implanted into patients to reach its final stability and full function in vivo, following maturation within the recipient’s [...] the transmission of infection agents, ensure the ability of the implant to grow in step with the patient (eg. in the case of children) Stem cell based bioartificial cardiac tissue Tissue engineered heart

doi: 10.1136/jme-2022-108814 Funer F, Salloch S (2023): 'Can I trust my patient?' Machine Learning support for predicting patient behaviour. J Med Ethics. doi: 10.1136/jme-2023-109094 Kotsis F, Bächle H [...] Salloch S (2024): Artificial Intelligence to support ethical decision-making for incapacitated patients: A survey among German anesthesiologists and internists. BMC Medical Ethics 25:78. doi: 10.1186 [...] Braun M, Wilkinson D, Sinnott-Armstrong W, Rid A, Wendler D, Savulescu J (2024). A Personalized Patient Preference Predictor for Substituted Judgments in Healthcare: Technically Feasible and Ethically

SARS-CoV-2 pandemic. COVID-19 / SARS-CoV-2 research at MHH Ranging from foundational research to maximal patient care Biomedecial technology & implants, transplantation & regeneration and infection & immunity are [...] - MHH is well-connected. Local Interdisciplinary - Ranging from foundational research to maximal patient care Regional Lower Saxony-Alliance, Funding by the state government National German Centre for Infection

Additional therapy with digitoxin reduces mortality and hospitalizations due to heart failure in patients with advanced heart failure (HFrEF). These results were published on August 29, 2025, in the New [...] August 2025 in the Hot Line Session, where new clinical studies that promise significant changes in patient treatment outcomes are presented.

Department of Human Genetics, we combine outstanding application-focused research with professional patient care. Our international and interdisciplinary research teams investigate the effects of genomic and [...] our research findings to help diagnose and treat genetic diseases. We are the point of contact for patients and families with suspected rare diseases as part of our genetic clinic. Our accredited diagnostic

RNA is diluted earlier than in available systems. 2. Generation of patient or disease-specific iPS cell lines Table of different patient-or disease-specific iPS cell lines in RG Martin In the Martin group [...] somatic cells into clinically applicable induced pluripotent stem cells (iPSCs) 2. Generation of patient or disease-specific iPS cell lines 3. Genetic modification of iPS cells and iPS cell-derived cell [...] different questions, such as the investigation of brain development. Meanwhile, a large number of human patient- or disease-specific iPS cell lines have been established in the research group. This collection

case-by-case decisions for individual curative trials. To ensure that the therapy is available to all patients as an established method in the future, a multicenter clinical trial is to test the new therapeutic [...] over viral defense Until the development of the new method, there was only one treatment option for patients taking immunosuppressive drugs: The immunosuppressants were discontinued. That way, there was a [...] specific T cells are transferred into the body of PML sufferers, they fight the virus there and the patient's condition stabilizes. Unique T-cell donation registry at MHH identifies matching donors "However

prove this in the brains of borderline patients who had been treated with a botulinum toxin injection in the glabellar region. Just four weeks later, the patients had significantly reduced symptoms, which [...] help of magnetic resonance imaging (MRI), they have visualised the neuronal effects in borderline patients. The result: botulinum toxin influences the so-called amygdala or almond nucleus in the temporal [...] less costly than some other therapy options and have a very good tolerance and acceptance among patients," Professor Krüger explains. Botulinum toxin curbs emotional constant fire in the tonsil nucleus