N., American journal of respiratory and critical care medicine, 2014. 189: 167), efficient genetic engineering of iPSCs (Merkert, S., Stem cell reports, 2014. 2: 107) as well as the development of technologies [...] characterization of genetically enriched hiPSC derived CMs and transplantation in a preclinical non-human primate model. Development of GMP compliant processes for the reprogramming and genetic modification of [...] Subproject 2 (MHH: Köhl, Martin; Miltenyi): GMP compliant scale up of iPSC-generation and genetic engineering Subproject 3 (MHH: Köhl, Zweigerdt; Miltenyi): Clinical scale up of iPSC-CM and MSC production

inflammation or injury. For 30 years, A1AT is used as a substitution therapy for emphysema patients with genetic A1AT deficiency, and shows very good safety and tolerance in many preclinical models. Current scientific [...] Dr. Rainer Blasczyk Department / Institute: Institute of Transfusion Medicine and Transplant Engineering COVID-19 convalescent plasma (CCP) donated by recovered patients is a promising treatment option

vectors dock onto the body cell via the vector envelope, the so-called capsid, and transfer their genetic cargo into the cell interior. There it is read and converted into the corresponding protein according [...] Christian Bär, baer.christian@mh-hannover.de , phone (0511) 532-2883. The original paper "AAV capsid engineering identified two novel variants with improved in vivo tropism for cardiomyocytes" can be found here

cell source, both in terms of basic science and in their application in biomedical research and engineering. The work of my group is intended to help identify the importance of these cells for the areas [...] students. Signaling pathways in regeneration: A molecular mechanism for tendon cell formation. Genetically modified MSCs differentiated in vitro into tendon-like cells. Implantation in vivo enabled cel [...] as an alternative to current biotherapies. Contributions to the MHH research focus "Biomedical Engineering, Implants" Graded implants. Biomedical implant research has so far concentrated on implants for

team led by Dr Anna Christina Dragon from the Institute of Transfusion Medicine and Transplant Engineering at Hannover Medical School (MHH) is now developing a new type of cell therapy to preserve organ [...] immune cells of the patient – the so-called T cells – which we convert into killer cells through genetic modification so that they precisely eliminate the responsible B cells that would otherwise produce

Thomas Thum (Institute of Molecular and Translational Therapeutic Strategies, IMTTS) Project: Engineering AAV in vivo tropism towards pre-apoptotic cardiomyocytes Shubham is class speaker! Lily Sophie [...] Sophie Rose , GERMANY, Rose.Lily@mh-hannover.de Supervisor: Prof. Dr. Ruthhild Weber (Human Genetics) Project: Ribosomal biogenesis genes and predisposition to brain tumors Tirthankar Saha , INDIA, Saha.Tir

CRISPR/Cas9 technology for precise genome editing in order to be able to correct disease-specific genetic mutations in a targeted manner. With regard to the public debate on the use of pluripotent (embryonic) [...] Pluripotent Stem Cell-Derived Hepatobiliary Organoids for Studies of Disease Mechanisms and Gene Engineering Approaches (Funding: REBIRTH - MWK Lower Saxony) iPS-based liver models and CRISPR/Cas-edited controls

for regenerative therapies were tested using novel (preferably postnatal) cell sources modified by genetic, epigenetic or matrix-based principles. HBRS - since 2000 Founded in 2000, the interdisciplinary [...] established research foci "Infection & Immunity", "Transplantation & Regeneration" and "Biomedical Engineering & Implants" as well as the new area of potential "Oncology". In the Excellence Initiative funding

after kidney transplant Further infomation: https://ntx360grad.de/ Copyright: NTX 360° Human genetics Human genetic studies Information will follow Lung Tx Lung-Tx For patients with the most severe end-stage [...] the development of novel tools for correction of genetic mutations in patient-specific stem cells and their use in disease modelling and tissue engineering. Based on our philosophy of creating synergies [...] clinicians and biomedical researchers with physical and chemical scientists and engineers, the fields of materials engineering, chemistry and physics have complemented our biomedical discoveries by developing

2011 Paulina Blazejewska Research Topic: Genetic susceptibility in mammals to influenza infection Supervisor: Prof. Dr. Klaus Schughart, Experimental Mouse Genetics, Helmholtz Centre for Infection Research [...] (BSc), Dr. G.R.D College of Science, India; MSc Human Genetics, Sri Ramachandra Medical College & Research Institute, India; Molecular Genetics (MSc), University of Leicester, England Melanie Rust Research [...] Dr. Ulrich Kalinke, Department of Experimental Infection Research, Twincore Academic Background: Genetics and Microbiology, Philipps-Universität Marburg, Germany Nicola Frericks Research Topic: Viral d