cells for tissue engineering approaches. J Tissue Eng 8:2041731417698852. Mogaldea, A., Goecke, T., Theodoridis, K., Haverich, A., Cebotari, S., and Hilfiker, A. 2017. Tissue Engineering of Vein Valves Based [...] A, Haverich A: Biological scaffolds for heart valve tissue engineering. In: Hauser, Hansjörg; Fussenegger, Martin M Editors. Tissue Engineering, Series: Methods in Molecular Medicine. 2nd ed. New York: [...] application of tissue engineered human heart valves using autologous progenitor cells. Circulation 2006;114, no. 1 Suppl:I132. Giere B, Hilfiker A, Haverich A: Tissue engineering -- in vitro culture of
N., American journal of respiratory and critical care medicine, 2014. 189: 167), efficient genetic engineering of iPSCs (Merkert, S., Stem cell reports, 2014. 2: 107) as well as the development of technologies [...] characterization of genetically enriched hiPSC derived CMs and transplantation in a preclinical non-human primate model. Development of GMP compliant processes for the reprogramming and genetic modification of [...] Subproject 2 (MHH: Köhl, Martin; Miltenyi): GMP compliant scale up of iPSC-generation and genetic engineering Subproject 3 (MHH: Köhl, Zweigerdt; Miltenyi): Clinical scale up of iPSC-CM and MSC production
inflammation or injury. For 30 years, A1AT is used as a substitution therapy for emphysema patients with genetic A1AT deficiency, and shows very good safety and tolerance in many preclinical models. Current scientific [...] Dr. Rainer Blasczyk Department / Institute: Institute of Transfusion Medicine and Transplant Engineering COVID-19 convalescent plasma (CCP) donated by recovered patients is a promising treatment option
Evaluation of a Novel Hyaluronic Acid–Laminin Hydrogel as Luminal Filler and Carrier System for Genetically Engineered Schwann Cells in Critical Gap Length Tubular Peripheral Nerve Graft in Rats. Dietzmeyer N
vectors dock onto the body cell via the vector envelope, the so-called capsid, and transfer their genetic cargo into the cell interior. There it is read and converted into the corresponding protein according [...] Christian Bär, baer.christian@mh-hannover.de , phone (0511) 532-2883. The original paper "AAV capsid engineering identified two novel variants with improved in vivo tropism for cardiomyocytes" can be found here
team led by Dr Anna Christina Dragon from the Institute of Transfusion Medicine and Transplant Engineering at Hannover Medical School (MHH) is now developing a new type of cell therapy to preserve organ [...] immune cells of the patient – the so-called T cells – which we convert into killer cells through genetic modification so that they precisely eliminate the responsible B cells that would otherwise produce
Thomas Thum (Institute of Molecular and Translational Therapeutic Strategies, IMTTS) Project: Engineering AAV in vivo tropism towards pre-apoptotic cardiomyocytes Shubham is class speaker! Lily Sophie [...] Sophie Rose , GERMANY, Rose.Lily@mh-hannover.de Supervisor: Prof. Dr. Ruthhild Weber (Human Genetics) Project: Ribosomal biogenesis genes and predisposition to brain tumors Tirthankar Saha , INDIA, Saha.Tir
Evaluation of a Novel Hyaluronic Acid–Laminin Hydrogel as Luminal Filler and Carrier System for Genetically Engineered Schwann Cells in Critical Gap Length Tubular Peripheral Nerve Graft in Rats. Dietzmeyer N [...] Haastert-Talini K (2014): In vitro cell-seeded chitosan filma for peripheral nerve tissue engineering. Tissue Engineering Part A; 20(17-18):2339-49. doi: 10.1089/ten.TEA.2013.0621. http://www.ncbi.nlm.nih.g [...] pathway via profilin. Hum Mol Genet. 2011 Dec 15;20(24):4865-78. Epub 2011 Sep 14. Kirsten Haastert-Talini (2011) Chapter 9: Experimental Approaches on Tissue engineering Repair of Peripheral Nerve Gaps
for regenerative therapies were tested using novel (preferably postnatal) cell sources modified by genetic, epigenetic or matrix-based principles. HBRS - since 2000 Founded in 2000, the interdisciplinary [...] established research foci "Infection & Immunity", "Transplantation & Regeneration" and "Biomedical Engineering & Implants" as well as the new area of potential "Oncology". In the Excellence Initiative funding
2011 Paulina Blazejewska Research Topic: Genetic susceptibility in mammals to influenza infection Supervisor: Prof. Dr. Klaus Schughart, Experimental Mouse Genetics, Helmholtz Centre for Infection Research [...] (BSc), Dr. G.R.D College of Science, India; MSc Human Genetics, Sri Ramachandra Medical College & Research Institute, India; Molecular Genetics (MSc), University of Leicester, England Melanie Rust Research [...] Dr. Ulrich Kalinke, Department of Experimental Infection Research, Twincore Academic Background: Genetics and Microbiology, Philipps-Universität Marburg, Germany Nicola Frericks Research Topic: Viral d