Kraft T., Montag J. Burst-like transcription of MYH7 in Hypertrophic Cardiomyopathy patients is mimicked in patient-derived hPSC-CMs; Acta Biochimica Polonica, Vol. 68 No. S1, 57; 2021 Burkart V., Kowalski [...] level 03, room 1320 Publications and Abstracts Scientific articles in peer-reviewed journals 2025 Patient-specific hiPSC-derived cardiomyocytes indicate allelic and contractile imbalance as pathogenic factor [...] decay factor UPF3B is associated with cMyBP-C haploinsufficiency in hypertrophic cardiomyopathy patients, Valentin Burkart, Kathrin Kowalski, Alina Disch, Denise Hilfiker-Kleiner , Sean Lal , Cristobal

situation. After significant accidents, the patient is taken over to the central emergency room, and computed tomography performs holistic imaging. If necessary, the patients are transferred to the intensive care [...] tumours that require follow-up treatment and tumour follow-up in our neurosurgical outpatient clinic, patients are also cared for on an interdisciplinary basis as part of the CNS tumour board. The interdisciplinary [...] course. The progress of the healing is discussed in interdisciplinary conferences. Upon recovery, the patient is discharged home through the regular ward. Otherwise, a rehabilitation procedure and transfer to

extent of functional changes caused by HCM mutations in cardiomyocytes of affected heterozygous patients is very different among cardiomyocytes isolated from the same tissue. For example, some cardiomyocytes [...] show for β-cardiac myosin heavy chain (β-MyHC) and cardiac troponin I (cTnI) that in each of the patients studied, individual cardiomyocytes from the same tissue express very different proportions of mutated [...] molecular level and to characterize them from cell to cell by investigating myocardial tissue from HCM patients. Furthermore, we analyze changes in signaling pathways at the single cell level, which are induced

SARS-CoV-2 pandemic. COVID-19 / SARS-CoV-2 research at MHH Ranging from foundational research to maximal patient care Biomedecial technology & implants, transplantation & regeneration and infection & immunity are [...] - MHH is well-connected. Local Interdisciplinary - Ranging from foundational research to maximal patient care Regional Lower Saxony-Alliance, Funding by the state government National German Centre for Infection

Department of Human Genetics, we combine outstanding application-focused research with professional patient care. Our international and interdisciplinary research teams investigate the effects of genomic and [...] our research findings to help diagnose and treat genetic diseases. We are the point of contact for patients and families with suspected rare diseases as part of our genetic clinic. Our accredited diagnostic

transplantation is the treatment of choice for many patients. Our Department of Nephrology and Hypertension is responsible for the evaluation of patients for kidney transplantation. We also provide medical

in workshops, a panel discussion, and through personal statements from our fellows: Patient Communication / Patient & Public Involvement Communication with Professional Societies Communication with the

gical factors that are important for the long-term preservation of renal function, but also for patient survival and quality of life. Specifically, we explore mechanisms of damage and mechanisms of renal [...] Wiesener M, Scheffner I and Koch A. Noninvasive Diagnosis of Acute Rejection in Renal Transplant Patients Using Mass Spectrometric Analysis of Urine Samples: A Multicenter Diagnostic Phase III Trial. Transplant [...] DOI: 10.1186/s12882-020-01723-x Scheffner I , Gietzelt M, Abeling T, Marschollek M and Gwinner W . Patient Survival After Kidney Transplantation: Important Role of Graft-sustaining Factors as Determined by

well as the Helmholtz Center for Infectious Disease is planning the establishment of a COVID-19 patient cohort and subsequent thorough molecular characterization of the cohort. The cohort enables the [...] corresponding metabolic pathways and therapy options. The COVID-19 cohort will encompass a total of 1000 patients with different disease severities and healthy controls. Samples of blood, live blood cells, plasma

nal exchange and cooperations with universities from abroad International Patient Office Contact and information for patients from abroad EU Office All about EU research grants and grant application (in