distress syndrome in preterm infants-"The OPTTIMMAL-Trial"-Optimizing PEEP To The IMMAture Lungs: study protocol of a randomized controlled trial . M. Waitz, C. Engel, R. Schloesser, U.h Rochwalsky, S. [...] H. Gerleve, K. Schneider, R. Haase, K. Böckenholt, K. Linnemann, E. Herting, W. Göpel.Multicenter Study. Arch Dis Child Fetal Neonatal Ed. 2020 Mar;105(2):190-195. Prospective surveillance of bacterial

phosphorylation and sumoylation on acto-myosin interaction and sarcomere function? This is being studied on isolated sarcomeric proteins in reconstituted systems and in cell culture models? find out more [...] proteins such as Alzheimer's-associated tau protein. In the long term, based on the single-molecule studies, development of bio-hybrid constructs with possible applications in nanotechnology is planned. find

(e.g., diabetes mellitus and dyslipidaemia), hypertension, and renal toxicity. In our preclinical studies, we have successfully shown that the body needs to accept the transplanted organ, which is dependent [...] patients with precision without having to suppress their immune system excessively. In our preclinical studies, we showed that transferring CAR Tregs leads to organ acceptance without affecting the recipient's

Prof. Dr. med. Ulrich Baumann is a specialist in pediatrics and adolescent medicine. He studied medicine in Göttingen, Bremen and Chur (Switzerland) and completed his training as a pediatrician in Bremen

of cells, tissues and organs in the embryo (often studied in model organisms such as frogs, fish and mice) can be closely recapitulated and studied by advanced strategies of hPSC differentiation in vitro [...] ubiquitous role in gene networks regulation, systematic studies in heart development and diseases are missing. We are specifically interested in studying the effect of small molecular inhibitors capable of [...] used for replacing animal studies in the process of drug discovery and development such as teratogenicity assessment or drug screenings in frame of congenital heart disease studies and tissue regeneration

functional studies are being conducted to measure the transepithelial ion conductance, ciliary beating and mucus properties in these transgenic hiPSC-derived airway epithelial cells. Our studies will create [...] ng factors requires extended culture periods to completely eliminate virus RNA entirely. In this study, we aim at developing a new reprogramming system based on a formerly described replication deficient [...] ____________________________________________________________________________________ In further studies, we are investigating why different cell types produced from iPS cells, which are a "juvenile" cell

Mark-Christian Jaboreck (RG Martin): “Development of a hiPSC-based cystic fibrosis lung disease model to study TMEM16A as an alternative therapeutic target in cystic fibrosis” Mikhail Magdei (RG Hilfiker): “Analysis

Network (international effort to rapidly repurpose existing drugs against COVID-19) International studies (therapy and diagnostics)

Sabine Pirr is a specialist for pediatrics and adolescent medicine with a focus on neonatology. She studied human medicine in Halle, Leipzig, Cologne and Zurich. Her training and further education as a pe

natural sciences. Students work independently in a project-oriented training program with an average study period of three years. Our PhD program strives to form a "bridge" between basic sciences and clinics [...] is limited to ~20 students per year. Detailed information on the content, structure and course of study can be found in the following sections. The MD/PhD program is integrated into the Hannover Biomedical [...] research project may be spent in partner institutes both in Germany and abroad. During the 3-year study period, all students have to attend about 80 hours of project-oriented seminars/courses as well as