Selected publications
Berman CL, Antonsson M, Batkai S, Bosgra S, Chopda GR, Driessen W, Foy J, Hassan C, Hu XS, Jang HG, Meena, Sanseverino M, Thum T, Wang Y, Wild M & Wu JT.
Nucleic Acid Ther. 2023 Aug 17. doi: 10.1089/nat.2023.0011. Online ahead of print. PMID: 37590469
COVID-19: Insights into long-term manifestations and lockdown impacts.
Hilbold E, Bär C, Thum T.
J Sport Health Sci. 2023 Mar 2:S2095-2546(23)00019-4. doi: 10.1016/j.jshs.2023.02.006. Epub ahead of print. PMID: 36868374; PMCID: PMC9977467.
Neufeldt D, Cushman S, Bär C, Thum T.
Cardiovasc Res. 2023 Jan 18:cvad013. doi: 10.1093/cvr/cvad013. Epub ahead of print. PMID: 36651915.
Gene Therapy and Cardiovascular Diseases.
Lu D, Cushman S, Thum T, Bär C.
Adv Exp Med Biol. 2023;1396:235-254. doi: 10.1007/978-981-19-5642-3_16. PMID: 36454471.
McKinsey TA, Foo R, Anene-Nzelu CG, Travers JG, Vagnozzi RJ, Weber N, Thum T.
Cardiovasc Res. 2023 Feb 3;118(18):3482-3498. doi: 10.1093/cvr/cvac142. PMID: 36004821.
Accelerating developments in heart failure.
Thum T, Lam CSP
Cardiovasc Res. 2023 Feb 3;118(18):3401-3402. doi: 10.1093/cvr/cvac185. PMID: 36583729
Waleczek FJG, Sansonetti M, Xiao K, Jung M, Mitzka S, Dendorfer A, Weber N, Perbellini F, Thum T.
Basic Res Cardiol. 2022 Nov 30;117(1):63. doi: 10.1007/s00395-022-00971-2. PMID: 36449104; PMCID: PMC9712328.
Accelerating cardiovascular research: recent advances in translational 2D and 3D heart models.
Mohr E, Thum T, Bär C.
Eur J Heart Fail. 2022 Oct;24(10):1778-1791. doi: 10.1002/ejhf.2631. Epub 2022 Aug 4. PMID: 35867781.
Rode L, Bär C, Groß S, Rossi A, Meumann N, Viereck J, Abbas N, Xiao K, Riedel I, Gietz A, Zimmer K, Odenthal M, Büning H, Thum T.
Mol Ther. 2022 Dec 7;30(12):3601-3618. doi: 10.1016/j.ymthe.2022.07.003. Epub 2022 Jul 9. PMID: 35810332; PMCID: PMC9734024.
Lu D, Chatterjee S, Xiao K, Riedel I, Huang CK, Costa A, Cushman S, Neufeldt D, Rode L, Schmidt A, Juchem M, Leonardy J, Büchler G, Blume J, Gern OL, Kalinke U, Wen Tan WL, Foo R, Vink A, van Laake LW, van der Meer P, Bär C, Thum T.
Eur Heart J. 2022 Nov 7;43(42):4496-4511. doi: 10.1093/eurheartj/ehac337. PMID: 35758064; PMCID: PMC9637424.
Neonatal injury models: integral tools to decipher the molecular basis of cardiac regeneration.
Costa A, Cushman S, Haubner BJ, Derda AA, Thum T, Bär C.
Basic Res Cardiol. 2022 May 3;117(1):26. doi: 10.1007/s00395-022-00931-w. PMID: 35503383; PMCID: PMC9064850.
Kreutzer FP, Meinecke A, Mitzka S, Hunkler HJ, Hobuß L, Abbas N, Geffers R, Weusthoff J, Xiao K, Jonigk DD, Fiedler J, Thum T.
Basic Res Cardiol. 2022 Mar 2;117(1):9. doi: 10.1007/s00395-022-00919-6. PMID: 35235052; PMCID: PMC8891108.
de Boer RA, Heymans S, Backs J, Carrier L, Coats AJS, Dimmeler S, Eschenhagen T, Filippatos G, Gepstein L, Hulot JS, Knöll R, Kupatt C, Linke WA, Seidman CE, Tocchetti CG, van der Velden J, Walsh R, Seferovic PM, Thum T.
Eur J Heart Fail. 2022 Mar;24(3):406-420. doi: 10.1002/ejhf.2414. Epub 2022 Jan 14. PMID: 34969177; PMCID: PMC9305112.
The long non-coding RNA NRON promotes the development of cardiac hypertrophy in the murine heart.
Hoepfner J, Leonardy J, Lu D, Schmidt K, Hunkler HJ, Biß S, Foinquinos A, Xiao K, Regalla K, Ramanujam D, Engelhardt S, Bär C, Thum T.
Mol Ther. 2022 Mar 2;30(3):1265-1274. doi: 10.1016/j.ymthe.2021.11.018. Epub 2021 Nov 29. PMID: 34856383; PMCID: PMC8899598.
Alternative strategies in cardiac preclinical research and new clinical trial formats.
Kreutzer FP, Meinecke A, Schmidt K, Fiedler J, Thum T.
Cardiovasc Res. 2022 Feb 21;118(3):746-762. doi: 10.1093/cvr/cvab075. PMID: 33693475; PMCID: PMC7989574.
LIPCAR Is Increased in Chronic Symptomatic HF Patients. A Sub-Study of the GISSI-HF Trial.
Meessen JMTA, Bär C, di Dona FM, Staszewsky LI, Di Giulio P, Di Tano G, Costa A, Leonardy J, Novelli D, Nicolis EB, Masson S, Pinet F, Thum T, Latini R.
Clin Chem. 2021 Nov 26;67(12):1721-1731. doi: 10.1093/clinchem/hvab197. PMID: 34751777.
Rosano G, Jankowska EA, Ray R, Metra M, Abdelhamid M, Adamopoulos S, Anker SD, Bayes-Genis A, Belenkov Y, Gal TB, Böhm M, Chioncel O, Cohen-Solal A, Farmakis D, Filippatos G, González A, Gustafsson F, Hill L, Jaarsma T, Jouhra F, Lainscak M, Lambrinou E, Lopatin Y, Lund LH, Milicic D, Moura B, Mullens W, Piepoli MF, Ponikowski P, Rakisheva A, Ristic A, Savarese G, Seferovic P, Senni M, Thum T, Tocchetti CG, Van Linthout S, Volterrani M, Coats AJS.
Eur J Heart Fail. 2021 Nov;23(11):1806-1818. doi: 10.1002/ejhf.2356. PMID: 34612556; PMCID: PMC8652673.
Hinkel R, Batkai S, Bähr A, Bozoglu T, Straub S, Borchert T, Viereck J, Howe A, Hornaschewitz N, Oberberger L, Jurisch V, Kozlik-Feldmann R, Freudenthal F, Ziegler T, Weber C, Sperandio M, Engelhardt S, Laugwitz KL, Moretti A, Klymiuk N, Thum T, Kupatt C.
J Am Coll Cardiol. 2021 Jun 15;77(23):2923-2935. doi: 10.1016/j.jacc.2021.04.028. PMID: 34112319.
Badimon L, Robinson EL, Jusic A, Carpusca I, deWindt LJ, Emanueli C, Ferdinandy P, Gu W, Gyöngyösi M, Hackl M, Karaduzovic-Hadziabdic K, Lustrek M, Martelli F, Nham E, Potočnjak I, Satagopam V, Schneider R, Thum T, Devaux Y.
Cardiovasc Res. 2021 Jul 7;117(8):1823-1840. doi: 10.1093/cvr/cvab094. PMID: 33839767; PMCID: PMC8083253.
Sahoo S, Adamiak M, Mathiyalagan P, Kenneweg F, Kafert-Kasting S, Thum T.
Circulation. 2021 Apr 6;143(14):1426-1449. doi: 10.1161/CIRCULATIONAHA.120.049254. Epub 2021 Apr 5. PMID: 33819075; PMCID: PMC8021236.
Telomerase therapy attenuates cardiotoxic effects of doxorubicin.
Chatterjee S, Hofer T, Costa A, Lu D, Batkai S, Gupta SK, Bolesani E, Zweigerdt R, Megias D, Streckfuss-Bömeke K, Brandenberger C, Thum T, Bär C.
Mol Ther. 2021 Apr 7;29(4):1395-1410. doi: 10.1016/j.ymthe.2020.12.035. Epub 2021 Jan 1. PMID: 33388418; PMCID: PMC8058493.
Ciccarelli M, Dawson D, Falcao-Pires I, Giacca M, Hamdani N, Heymans S, Hooghiemstra A, Leeuwis A, Hermkens D, Tocchetti CG, van der Velden J, Zacchigna S, Thum T.
Cardiovasc Res. 2021 Nov 1;117(12):2416-2433. doi: 10.1093/cvr/cvab009. PMID: 33483724; PMCID: PMC8562335.
Circulating cardiovascular microRNAs in critically ill COVID-19 patients.
Garg A, Seeliger B, Derda AA, Xiao K, Gietz A, Scherf K, Sonnenschein K, Pink I, Hoeper MM, Welte T, Bauersachs J, David S, Bär C, Thum T.
Eur J Heart Fail. 2021 Mar;23(3):468-475. doi: 10.1002/ejhf.2096. Epub 2021 Mar 5. PMID: 33421274; PMCID: PMC8014268.
Täubel J, Hauke W, Rump S, Viereck J, Batkai S, Poetzsch J, Rode L, Weigt H, Genschel C, Lorch U, Theek C, Levin AA, Bauersachs J, Solomon SD, Thum T.
Eur Heart J. 2021 Jan 7;42(2):178-188. doi: 10.1093/eurheartj/ehaa898. PMID: 33245749; PMCID: PMC7954267.
CDR132L improves systolic and diastolic function in a large animal model of chronic heart failure.
Batkai S, Genschel C, Viereck J, Rump S, Bär C, Borchert T, Traxler D, Riesenhuber M, Spannbauer A, Lukovic D, Zlabinger K, Hašimbegović E, Winkler J, Garamvölgyi R, Neitzel S, Gyöngyösi M, Thum T.
Eur Heart J. 2021 Jan 7;42(2):192-201. doi: 10.1093/eurheartj/ehaa791. Erratum in: Eur Heart J. 2021 Oct 14;42(39):4036. PMID: 33089304; PMCID: PMC7813625.
Zacchigna S, Paldino A, Falcão-Pires I, Daskalopoulos EP, Dal Ferro M, Vodret S, Lesizza P, Cannatà A, Miranda-Silva D, Lourenço AP, Pinamonti B, Sinagra G, Weinberger F, Eschenhagen T, Carrier L, Kehat I, Tocchetti CG, Russo M, Ghigo A, Cimino J, Hirsch E, Dawson D, Ciccarelli M, Oliveti M, Linke WA, Cuijpers I, Heymans S, Hamdani N, de Boer M, Duncker DJ, Kuster D, van der Velden J, Beauloye C, Bertrand L, Mayr M, Giacca M, Leuschner F, Backs J, Thum T.
Cardiovasc Res. 2021 Jan 1;117(1):43-59. doi: 10.1093/cvr/cvaa110. PMID: 32365197.
Groß S, Jahn C, Cushman S, Bär C, Thum T. SARS-CoV-2 receptor ACE2-dependent
implications on the cardiovascular system: From basic science to clinical
implications. J Mol Cell Cardiol. 2020 Apr 30;144:47-53. doi:
10.1016/j.yjmcc.2020.04.031. Epub ahead of print. PMID: 32360703; PMCID:
PMC7191280.
Zacchigna S, Paldino A, Falcão-Pires I, Daskalopoulos EP, Dal Ferro M, Vodret
S, Lesizza P, Cannatà A, Miranda-Silva D, Lourenço AP, Pinamonti B, Sinagra G,
Weinberger F, Eschenhagen T, Carrier L, Kehat I, Tocchetti CG, Russo M, Ghigo A,
Cimino J, Hirsch E, Dawson D, Ciccarelli M, Oliveti M, Linke WA, Cuijpers I,
Heymans S, Hamdani N, de Boer M, Duncker D, Kuster D, van der Velden J, Beauloye
C, Bertrand L, Mayr M, Giacca M, Leuschner F, Backs J, Thum T; Working Group on
Myocardial Function of the European Society of Cardiology.. Toward
standardization of echocardiography for the evaluation of left ventricular
function in adult rodents: a position paper of the ESC Working Group on
Myocardial Function. Cardiovasc Res. 2020 May 4:cvaa110. doi:
10.1093/cvr/cvaa110. Epub ahead of print. PMID: 32365197.
Garg A, Foinquinos A, Jung M, Janssen-Peters H, Biss S, Bauersachs J, Gupta
SK, Thum T. MiRNA-181a is a novel regulator of aldosterone-mineralocorticoid
receptor-mediated cardiac remodelling. Eur J Heart Fail. 2020 Apr 18. doi:
10.1002/ejhf.1813. Epub ahead of print. PMID: 32304626.
Huang CK, Kafert-Kasting S, Thum T. Preclinical and Clinical Development of
Noncoding RNA Therapeutics for Cardiovascular Disease. Circ Res. 2020 Feb
28;126(5):663-678. doi: 10.1161/CIRCRESAHA.119.315856. Epub 2020 Feb 27. PMID:
32105576; PMCID: PMC7043728.
Foinquinos A, Batkai S, Genschel C, Viereck J, Rump S, Gyöngyösi M, Traxler
D, Riesenhuber M, Spannbauer A, Lukovic D, Weber N, Zlabinger K, Hašimbegović E,
Winkler J, Fiedler J, Dangwal S, Fischer M, de la Roche J, Wojciechowski D,
Kraft T, Garamvölgyi R, Neitzel S, Chatterjee S, Yin X, Bär C, Mayr M, Xiao K,
Thum T. Preclinical development of a miR-132 inhibitor for heart failure
treatment. Nat Commun. 2020 Jan 31;11(1):633. doi: 10.1038/s41467-020-14349-2.
PMID: 32005803; PMCID: PMC6994493.
Schimmel K, Jung M, Foinquinos A, José GS, Beaumont J, Bock K, Grote-Levi L,
Xiao K, Bär C, Pfanne A, Just A, Zimmer K, Ngoy S, López B, Ravassa S, Samolovac
S, Janssen-Peters H, Remke J, Scherf K, Dangwal S, Piccoli MT, Kleemiss F,
Kreutzer FP, Kenneweg F, Leonardy J, Hobuß L, Santer L, Do QT, Geffers R,
Braesen JH, Schmitz J, Brandenberger C, Müller DN, Wilck N, Kaever V, Bähre H,
Batkai S, Fiedler J, Alexander KM, Wertheim BM, Fisch S, Liao R, Diez J,
González A, Thum T. Natural Compound Library Screening Identifies New Molecules
for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction. Circulation.
2020 Mar 3;141(9):751-767. doi: 10.1161/CIRCULATIONAHA.119.042559. Epub 2020 Jan
17. PMID: 31948273; PMCID: PMC7050799.
Stojanović SD, Fiedler J, Bauersachs J, Thum T, Sedding DG. Senescence-
induced inflammation: an important player and key therapeutic target in
atherosclerosis. Eur Heart J. 2020 Jan 3:ehz919. doi: 10.1093/eurheartj/ehz919.
Epub ahead of print. PMID: 31898722.
Kenneweg F, Bang C, Xiao K, Boulanger CM, Loyer X, Mazlan S, Schroen B,
Hermans-Beijnsberger S, Foinquinos A, Hirt MN, Eschenhagen T, Funcke S,
Stojanovic S, Genschel C, Schimmel K, Just A, Pfanne A, Scherf K, Dehmel S,
Raemon-Buettner SM, Fiedler J, Thum T. Long Noncoding RNA-Enriched Vesicles
Secreted by Hypoxic Cardiomyocytes Drive Cardiac Fibrosis. Mol Ther Nucleic
Acids. 2019 Dec 6;18:363-374. doi: 10.1016/j.omtn.2019.09.003. Epub 2019 Sep 13.
PMID: 31634682; PMCID: PMC6807307.
Santer L, Bär C, Thum T. Circular RNAs: A Novel Class of Functional RNA
Molecules with a Therapeutic Perspective. Mol Ther. 2019 Aug 7;27(8):1350-1363.
doi: 10.1016/j.ymthe.2019.07.001. Epub 2019 Jul 9. PMID: 31324392; PMCID:
PMC6697450.
Lu D, Thum T. RNA-based diagnostic and therapeutic strategies for
cardiovascular disease. Nat Rev Cardiol. 2019 Nov;16(11):661-674. doi:
10.1038/s41569-019-0218-x. Epub 2019 Jun 11. PMID: 31186539.
miR-212/132 Cluster Modulation Prevents Doxorubicin-Mediated Atrophy and Cardiotoxicity.
Gupta SK, Garg A, Avramopoulos P, Engelhardt S, Streckfuss-Bömeke K, Batkai S, Thum T (2018).
Mol Ther. 2019 Jan 2;27(1):17-28. Epub 2018 Nov 13
Gupta SK, Garg A, Bär C, Chatterjee S, Foinquinos A, Milting H, Streckfuß-Bömeke K, Fiedler J, Thum T (2018)
Circ Res. 122(2):246-254. [Epub 2017 Nov 13]
Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling.
Sassi Y, Avramopoulos P, Ramanujam D, Grüter L, Werfel S, Giosele S, Brunner AD, Esfandyari D, Papadopoulou AS, De Strooper B, Hübner N, Kumarswamy R, Thum T, Yin X, Mayr M, Laggerbauer B, Engelhardt S (2017).
Nat Commun. 8(1):1614.
Beermann J, Kirste D, Iwanov K, Lu D, Kleemiß F, Kumarswamy R, Schimmel K, Bär C, Thum T (2017).
Cell Death Differ. 25(2):307-318. [Epub 2017 Nov 3]
Masson S, Batkai S, Beermann J, Bär C, Pfanne A, Thum S, Magnoli M, Balconi G, Nicolosi GL, Tavazzi L, Latini R, Thum T (2017).
Eur J Heart Fail. 20(1):78-85 [Epub 2017 Oct 12]
Schauerte C, Hübner A, Rong S, Wang S, Shushakova N, Mengel M, Dettling A, Bang C, Scherf K, Koelling M, Melk A, Haller H, Thum T, Lorenzen JM (2017).
Kidney Int. 92(3):646-656.
Piccoli MT, Gupta SK, Viereck J, Foinquinos A, Samolovac S, Kramer FL, Garg A, Remke J, Zimmer K, Batkai S, Thum T.
Circ Res. 2017 Aug 18;121(5):575-583. doi: 10.1161/CIRCRESAHA.117.310624. Epub 2017 Jun 19.
Therapeutic miR-21 Silencing Ameliorates Diabetic Kidney Disease in Mice.
Kölling M, Kaucsar T, Schauerte C, Hübner A, Dettling A, Park JK, Busch M, Wulff X, Meier M, Scherf K, Bukosza N, Szénási G, Godó M, Sharma A, Heuser M, Hamar P, Bang C, Haller H, Thum T, Lorenzen JM (2017).
Mol Ther. 25(1):165-180.
de Gonzalo-Calvo D, Kenneweg F, Bang C, Toro R, van der Meer RW, Rijzewijk LJ, Smit JW, Lamb HJ, Llorente-Cortes V, Thum T.
Sci Rep. 2016 Nov 22;6:37354. doi: 10.1038/srep37354.
Long Noncoding RNAs in Cardiovascular Pathology, Diagnosis, and Therapy.
Bär C, Chatterjee S, Thum T.
Circulation. 2016 Nov 8; 134(19):1484-1499.
MicroRNA-based Therapy of Gata2-deficient Vascular Disease.
Hartmann D, Fiedler J, Sonnenschein K, Just A, Pfanne A, Zimmer K, Remke J, Foinquinos A, Butzlaff M, Schimmel K, Maegdefessel L, Hilfiker-Kleiner D, Lachmann N, Schober A, Froese N, Heineke J, Bauersachs J, Batkai S, Thum T.
Circulation. 2016 Oct 25. pii: CIRCULATIONAHA.116.022478. [Epub ahead of print]
Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches.
Beermann J, Piccoli MT, Viereck J, Thum T.
Physiol Rev. 2016 Oct; 96(4):1297-325. doi: 10.1152/physrev.00041.2015.
Preclinical Development of a MicroRNA-Based Therapy for Elderly Patients With Myocardial Infarction.
Gupta SK, Foinquinos A, Thum S, Remke J, Zimmer K, Bauters C, de Groote P, Boon RA, de Windt LJ, Preissl S, Hein L, Batkai S, Pinet F, Thum T.
J Am Coll Cardiol. 2016 Oct 4;68(14):1557-71. doi: 10.1016/j.jacc.2016.07.739.
Identification of miR-126 as a new regulator of skin aging.
Fiedler J, Grönniger E, Pfanne A, Brönneke S, Schmidt K, Falk CS, Wenck H, Terstegen L, Thum T, Winnefeld M.
Exp Dermatol. 2016 Aug 30. doi: 10.1111/exd.13173. [Epub ahead of print]
Long noncoding RNA Chast promotes cardiac remodeling.
Viereck J, Kumarswamy R, Foinquinos A, Xiao K, Avramopoulos P, Kunz M, Dittrich M, Maetzig T, Zimmer K, Remke J, Just A, Fendrich J, Scherf K, Bolesani E, Schambach A, Weidemann F, Zweigerdt R, de Windt LJ, Engelhardt S, Dandekar T, Batkai S, Thum T.
Sci Transl Med. 2016 Feb 17;8(326):326ra22. doi: 10.1126/scitranslmed.aaf1475.
Li XG, Roivainen A, Bergman J, Heinonen A, Bengel F, Thum T, Knuuti J.
Chem Commun (Camb). 2015 Jun 2;51(48):9821-4.
Lorenzen JM, Schauerte C, Hübner A, Kölling M, Martino F, Scherf K, Batkai S, Zimmer K, Foinquinos A, Kaucsar T, Fiedler J, Kumarswamy R, Bang C, Hartmann D, Gupta SK, Kielstein J, Jungmann A, Katus HA, Weidemann F, Müller OJ, Haller H, Thum T.
Eur Heart J. 2015 Apr 21. pii: ehv109.
Long noncoding RNAs in cardiac development and ageing.
Devaux Y, Zangrando J, Schroen B, Creemers EE, Pedrazzini T, Chang CP, Dorn GW 2nd, Thum T, Heymans S; Cardiolinc network.
Nat Rev Cardiol. 2015 Apr 7. doi: 10.1038/nrcardio.2015.55
Dangwal S, Stratmann B, Bang C, Lorenzen JM, Kumarswamy R, Fiedler J, Falk CS, Scholz CJ, Thum T, Tschoepe D.
Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1480-8.
MicroRNA signatures differentiate preserved from reduced ejection fraction heart failure.
Watson CJ, Gupta SK, O'Connell E, Thum S, Glezeva N, Fendrich J, Gallagher J, Ledwidge M, Grote-Levi L, McDonald K, Thum T.
Eur J Heart Fail. 2015 Apr;17(4):405-15.
Long noncoding RNAs and microRNAs in cardiovascular pathophysiology.
Thum T, Condorelli G.
Circ Res. 2015 Feb 13;116(4):751-62.
Bang C, Batkai S, Dangwal S, Gupta SK, Foinquinos A, Holzmann A, Just A, Remke J, Zimmer K, Zeug A, Ponimaskin E, Schmiedl A, Yin X, Mayr M, Halder R, Fischer A, Engelhardt S, Wei Y, Schober A, Fiedler J, Thum T.
J Clin Invest. 2014;124:2136-2146.
Fiedler J, Stohr A, Gupta SK, Hartmann D, Holzmann A, Just A, Hansen A, Hilfiker-Kleiner D, Eschenhagen T, Thum T.
Antioxid Redox Signal. 2014;21:1167-1176.
Circulating long noncoding RNA, LIPCAR, predicts survival in patients with heart failure.
Kumarswamy R, Bauters C, Volkmann I, Maury F, Fetisch J, Holzmann A, Lemesle G, de Groote P, Pinet F, Thum T.
Circ Res. 2014;114:1569-1575.
MicroRNA-24 antagonism prevents renal ischemia reperfusion injury.
Lorenzen JM, Kaucsar T, Schauerte C, Schmitt R, Rong S, Hubner A, Scherf K, Fiedler J, Martino F, Kumarswamy R, Kolling M, Sorensen I, Hinz H, Heineke J, van Rooij E, Haller H, Thum T.
J Am Soc Nephrol. 2014.
MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart.
Jazbutyte V, Fiedler J, Kneitz S, Galuppo P, Just A, Holzmann A, Bauersachs J, Thum T.
Age (Dordr). 2013;35:747-762.
The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.
Ucar A, Gupta SK, Fiedler J, Erikci E, Kardasinski M, Batkai S, Dangwal S, Kumarswamy R, Bang C, Holzmann A, Remke J, Caprio M, Jentzsch C, Engelhardt S, Geisendorf S, Glas C, Hofmann TG, Nessling M, Richter K, Schiffer M, Carrier L, Napp LC, Bauersachs J, Chowdhury K, Thum T.
Nat Commun. 2012;3:1078.
MicroRNA-24 regulates vascularity after myocardial infarction.
Fiedler J, Jazbutyte V, Kirchmaier BC, Gupta SK, Lorenzen J, Hartmann D, Galuppo P, Kneitz S, Pena JT, Sohn-Lee C, Loyer X, Soutschek J, Brand T, Tuschl T, Heineke J, Martin U, Schulte-Merker S, Ertl G, Engelhardt S, Bauersachs J, Thum T.
Circulation. 2011;124:720-730.
miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2.
Pfaff N, Fiedler J, Holzmann A, Schambach A, Moritz T, Cantz T, Thum T.
EMBO Rep. 2011;12:1153-1159.
Comparison of different miR-21 inhibitor chemistries in a cardiac disease model.
Thum T, Chau N, Bhat B, Gupta SK, Linsley PS, Bauersachs J, Engelhardt S.
J Clin Invest. 2011;121:461-2; author reply 462-3.
Thum T, Schmitter K, Fleissner F, Wiebking V, Dietrich B, Widder JD, Jazbutyte V, Hahner S, Ertl G, Bauersachs J.
Eur Heart J. 2011;32:1275-1286.
Ucar A, Vafaizadeh V, Jarry H, Fiedler J, Klemmt PA, Thum T, Groner B, Chowdhury K.
Nat Genet. 2010;42:1101-1108.
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts.
Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, Castoldi M, Soutschek J, Koteliansky V, Rosenwald A, Basson MA, Licht JD, Pena JT, Rouhanifard SH, Muckenthaler MU, Tuschl T, Martin GR, Bauersachs J, Engelhardt S.
Nature. 2008;456:980-984.
MicroRNAs in the human heart: A clue to fetal gene reprogramming in heart failure.
Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, Doevendans PA, Mummery CL, Borlak J, Haverich A, Gross C, Engelhardt S, Ertl G, Bauersachs J.
Circulation. 2007;116:258-267.
Thum T, Hoeber S, Froese S, Klink I, Stichtenoth DO, Galuppo P, Jakob M, Tsikas D, Anker SD, Poole-Wilson PA, Borlak J, Ertl G, Bauersachs J.
Circ Res. 2007;100:434-443.
For a complete list of publications please go to PubMed.