Azriel S, Rokney A, Valinsky L, Rahav G, Grassl GA*, Gal-Mor O*.Differences in the expression of SPI-1 genes pathogenicity and epidemiology between the emerging Salmonella enterica serovar Infantis and the model [...] Bleich A, Johnsen JM, Vallance BA, Baines JF, Grassl GA. 2015. Expression of the blood-group-related gene B4galnt2 alters susceptibility to Salmonella infection. PLoS Pathogens. 11 e1005008. Grassl GA*, Valdez
Hepatology and Endocrinology, OE 6810, Project: Identification and Functional Characterization of Cancer Genes in Pancreatic Cancer. Final exam November 2019 Sofia Gialesaki GREECE Supervisor: PD Dr. Jan-Henning [...] Project: Identification and functional characterization of novel cervical cancer susceptibility genes. Final exam June 2020. Theresia Reindl GERMANY Supervisor: Prof. Dr. Dietmar Manstein, Bio-physical
Klein, Pediatric Hematology and Oncology, OE 6780, project: The use of morpholino based knockdown gene technology as well as genetic studies to determine the function of HAX1 in zebrafish Final exam November [...] mouse models of leukemia; 2.Mechanisms of induction of immunologic tolerance by leukemic cells; 3.Gene therapy for hematologic disorders Final exam November 2012 Theodros Solomon Tsegaye (MD) ETHIOPIA
supervisor: Prof. Dr. Rudolph, now University of Ulm project: Analysis of the role of stanniocalcins genes and apoptosis pathways during cellular and organismal ageing Final exam June 2009 Lydia Asrat Haile [...] INDIA supervisor: Prof. Dr. Kispert, Molecular Biology, OE 5250, project: Functional analysis of Tbx gene in heart development Final exam November 2009 Inga Sörensen-Zender GERMANY supervisor: Prof. Dr. Gossler
Ramesh Pandey (Vet.) INDIA superrvisor: Prof. Dr. Kabesch, Paediatric Pneumology, project: TLR pathway genes and susceptibility for allergy and atopic diseases Final exam January 2013 Ruhi Phaltane INDIA supervisor: [...] project: Humanized models to assess the genotoxicity of viral vectors in the context of hematopoietic gene therapy and in vivo selection Final exam November 2013. Georgios Sogkas GREECE supervisor: Prof. Dr
Gentransfer zur genetischen Manipulation hämatopoetischer Zellen. Dazu gehört die Überexpression von Genen und miRNAs ebenso wie die spezifische Inhibition der Genexpression durch RNA-Interferenz (RNAi). Daneben [...] Identifizierung möglicher potentieller Zielstrukturen in Leukämiezellen In bisherigen Arbeiten wurden gen-spezifische, synthetische siRNAs (transiente RNAi) sowie lentiviral-codierte shRNAs (stabile RNAi)
zusätzlichen Speichervolumen wächst mit dem Ausbau digitaler Analyseverfahren z.B. durch den Einsatz von Gen-Sequenzern oder im Rahmen von rechenintensiven Forschungsprojekten. Dafür stehen moderne Speichert
acquisition of additional mutational events promoting clonal evolution and disease development. The genes most frequently affected by age-related somatic variants in blood cells are coding for the DNA-methylation [...] complex as well as the histone demethylase LSD1, are critical for the establishment of pathogenic gene expression programs in clonal subpopulations of blood cells. Based on published and our preliminary [...] selective inhibitors of these chromatin binding proteins can reverse the aberrant chromatin state and gene expression signatures in a genotype selective manner and target pathogenic clones in xenograft models
en, liebe Patienten/innen und Angehörige, nach der großen Teilnehmerzahl und positiven Rückmeldun gen zu unseren Online-Angeboten zur Corona-Impfung wol len wir dieses Konzept eines Online-Arzt-Patien
the small GTPase Rac1 is activated after receptor internalization which is key for the IL-1-induced gene expression. The small GTPase Rac1 is an endosome-specific “sorting adaptor” in IL-1 signaling. However