Funding (Selection): CardioReGenix : Development of Next-Generation Gene Therapies for Cardiovascular Disease Duration: January 1, 2019 – June 30, 2024 TRAIN-HEART : RNA therapeutics for heart failure

Hematology, project: Development of a novel alpharetroviral vector system for hematopoietic stem cell gene therapy in Wiskott Aldrich Syndrome Final exam November 2014. Sebastian Goy GERMANY supervisor: Dr

Zelle in das Programm aufgenommen und um Transkriptom-Analysen zu ermöglichen, haben wir uns für PaxGene-Tubes entschieden, in denen man RNA hochstandardisiert lagern kann. Außerdem nehmen wir Abstriche

ncbi.nlm.nih.gov/34859450/ Rezalotfi A, Fritz L, Förster R*, Bošnjak B* . Challenges of CRISPR-Based Gene Editing in Primary T Cells. Int. J. Mol. Sci. 2022 23, 1689. (* equally contributing corresponding

Pieper, Schlüter D (2019) Diversity of bacteria exhibiting bile acid-inducible 7α-dehydroxylation genes in the human gut. Comput. Struct. Biotechnol. J. 17:1016-1019. doi 10.1016/j.csbj.2019.07.012.

Kosanke, M., Montag, J., Thum, T., Zweigerdt, R., Kraft, T., Iorga, B., and Meissner, J.D. (2023), J Gen Physiol (2023) 155 (11): e202313377, https://doi.org/10.1085/jgp.202313377 , Online ahead of print

nih.gov/pubmed/30785826 (Apr 2019) Unsere Arbeit zu HER2 Mutationen im lobulären Karzinom ist in Genes Chromosomes and Cancer erschienen: www.ncbi.nlm.nih.gov/pubmed/30520184 (Jan 2019) Die AG klinische [...] nih.gov/36347887/ ( Nov. 2022) Together with the West German Study Group (WSG) we have characterized gene expression pattern in breast cancers under anti-HER2 therapy with trastuzumab/pertuzumab. The results [...] German Study Group (WSG) we have conducted the first clinical trial worldwide, that has combined a gene expression-based assay (Oncotype DX Recurrence Score) with Ki67-response evaluation after pre-operative

Farris AB, Geldenhuys L, Loupy A, Nickeleit V, Rabant M, Randhawa P, Regele H, Mengel M. Intragraft Gene Expression in Native Kidney BK Virus Nephropathy versus T‐Cell Mediated Rejection: Prospects for Molecular [...] Vogtmann J, Schipper E, Büsche G, Schlue J, Kreipe H, Lehmann U. Feasibility of Combined Detection of Gene Mutations and Fusion Transcripts in Bone Marrow Trephines from Leukemic Neoplasms . J Mol Diagn. 2020 [...] Harbeck N. Efficacy of deescalated chemotherapy according to PAM50 subtypes, immune and proliferation genes in triple-negative early breast cancer: Primary translational analysis of the WSG-ADAPT-TN trial.

Hasemeier B, Länger F, Kreipe H: Promoter hypermethylation of the death-associated protein kinase gene in breast cancer is associated with the invasive lobular subtype. Cancer Res 2002; 62(22): 6634-8 [...] 118: 675-82 Warmann S, Hunger M, Teichmann B, Flemming P, Gratz KF, Fuchs J: The role of the MDR1 gene in the development of multidrug resistance in human hepatoblastoma: clinical course and in vivo model

Gentner B, Casanova JL, Bustamante J, Schambach A, Kalinke U, Lachmann N. Hematopoietic stem cell gene therapy for IFNgammaR1 deficiency protects mice from mycobacterial infections. Blood 2017; 131(5):533-545 [...] Künzel S, Suwandi A, Grassl GA, Rosenstiel P, Baines JF. Multigenerational Influences of the Fut2 gene on the dynamics of the gut microbiota in mice. Front Microbiol 2017; 8:991. Rosner BM, Schielke A