Veröffentlichungen 2020

 

Ackermann M, Haake K, Kempf H, Kaschutnig P, Weiss A-C, Nguyen AH, Abeln M, Merkert S, Kühnel MP, Hartmann D, Jonigk D, Thum T, Kispert A, Milsom MD, Lachmann N. 

A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification.

Haematologica. 2020 Apr 23:haematol.2019.228064. doi: 10.3324/haematol.2019.228064. Online ahead of print.

 

Ackermann M, Mentzer SJ, Kolb M, Jonigk D.

Inflammation and intussusceptive angiogenesis in COVID-19: everything in and out of flow.

Eur Respir J. 2020 Nov 12;56(5):2003147. doi: 10.1183/13993003.03147-2020. Print 2020 Nov.PMID: 33008942 Free PMC article.

 

Ackermann M, Stark H, Neubert L, Schubert S, Borchert P, Linz F, Wagner WL, Stiller W, Wielpütz M, Hoefer A, Haverich A, Mentzer SJ, Shah HR, Welte T, Kuehnel M, Jonigk D

Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases.

Eur Respir J. 2020 Mar 12;55(3):1900933. doi: 10.1183/13993003.00933-2019. Print 2020 Mar.

 

Ackermann M, Verleden SE, Kuehnel M, Haverich A, Welte T, Laenger F, Vanstapel A, Werlein C, Stark H, Tzankov A, Li WW, Li VW, Mentzer SJ, Jonigk D

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.

N Engl J Med. 2020 Jul 9;383(2):120-128. doi: 10.1056/NEJMoa2015432. Epub 2020 May 21.

 

Ackermann M, Mentzer SJ, Jonigk D.

Pulmonary Vascular Pathology in Covid-19. Reply.

N Engl J Med. 2020 Aug 27;383(9):888-889. doi: 10.1056/NEJMc2022068. Epub 2020 Jul 17.

 

Ackermann M, Mentzer SJ, Jonigk D.

Visualization of SARS-CoV-2 in the Lung. Reply.

N Engl J Med. 2020 Dec 31;383(27):2689-2690. doi: 10.1056/NEJMc2030450.

 

Adam BA, Kikic Z, Wagner S, Bouatou Y, Gueguen J, Drieux F, Reid G, Du K, Bräsen JH, D'Agati VD, Drachenberg CB, Farkash EA, Farris AB, Geldenhuys L, Loupy A, Nickeleit V, Rabant M, Randhawa P, Regele H, Mengel M.

Intragraft Gene Expression in Native Kidney BK Virus Nephropathy versus T‐Cell Mediated Rejection: Prospects for Molecular Diagnosis and Risk Prediction.

Am J Transplant. 2020 May 5. doi: 10.1111/ajt.15980. Online ahead of print.

 

Al Krinawe Y, Esmaeilzadeh M, Hartmann C, Krauss JK, Hermann EJ. 

Pediatric rosette-forming glioneuronal tumor of the septum pellucidum.

Childs Nerv Syst. 2020 Mar 26. doi: 10.1007/s00381-020-04575-w. Online ahead of print.

 

Banan R, Stichel D, Bleck A, Hong B, Lehmann U, Suwala A, Reinhardt A, Schrimpf D, Buslei R, Stadelmann C, Ehlert K, Prinz M, Acker T, Schittenhelm J, Kaul D, Schweizer L, Capper D, Harter PN, Etminan N, Jones DTW, Pfister SM, Herold-Mende C, Wick W, Sahm F, von Deimling A, Hartmann C, Reuss DE.

Infratentorial IDH-mutant astrocytoma is a distinct subtype.

Acta Neuropathol. 2020 Oct;140(4):569-581. doi: 10.1007/s00401-020-02194-y. Epub 2020 Aug 10.PMID: 32776277

 

Bartels S, Hasemeier B, Vogtmann J, Schipper E, Büsche G, Schlue J, Kreipe H, Lehmann U.

Feasibility of Combined Detection of Gene Mutations and Fusion Transcripts in Bone Marrow Trephines from Leukemic Neoplasms.

J Mol Diagn. 2020 Apr;22(4):591-598. doi: 10.1016/j.jmoldx.2020.01.004. Epub 2020 Feb 7.PMID: 32036087

 

Bartels S, Faisal M, Büsche G, Schlue J, Hasemeier B, Schipper E, Vogtmann J, Westphal L, Lehmann U, Kreipe H.

Mutations associated with age-related clonal hematopoiesis in PMF patients with rapid progression to myelofibrosis.

Leukemia. 2020 May;34(5):1364-1372. doi: 10.1038/s41375-019-0668-5. Epub 2019 Nov 27.PMID: 31776465

 

Bartels S, Faisal M, Büsche G, Schlue J, Hasemeier B, Schipper E, Vogtmann J, Westphal L, Lehmann U, Kreipe H.

[Bone marrow fibrosis in primary myelofibrosis in relation to myelodysplasia- and age-related mutations of hematopoietic cells].

Pathologe. 2020 Oct 28. doi: 10.1007/s00292-020-00828-2. Online ahead of print.PMID: 33113046 Review. German.

 

Behling F, Barrantes-Freer A, Behnes C L, Stockhammer F, Rohde V,  Adel-Horowski A, Rodríguez-Villagra OA, Barboza MA, Brück W, Lehmann U, Stadelmann C, Hartmann C

Expression of Olig2, Nestin, NogoA and AQP4 have no impact on overall survival in IDH-wildtype glioblastoma.

PLoS One. 2020 Mar 11;15(3):e0229274. doi: 10.1371/journal.pone.0229274. eCollection 2020.PMID: 32160197 Free PMC article.

 

Behr J, Günther A, Bonella F, Dinkel J, Fink L, Geiser T, Geißler K, Gläser S, Handzhhiev S, Jonigk D, Koschel D, Kreuter M, Leuschner G, Markart P, Prasse A, Schönfeld N, Schupp JC, Sitter H, Müller-Quernheim J, Costabel U. 

[German Guideline for Idiopathic Pulmonary Fibrosis].

Pneumologie. 2020 May;74(5):263-293. doi: 10.1055/a-1120-3531. Epub 2020 Mar 30.PMID: 32227328 German.

 

Bogaard HJ , Legchenko E , Ackermann M , Kühnel MP, Jonigk DD, Chaudhary KR, Sun X, Stewart DJ, Hansmann G. 

The Adult Sprague-Dawley Sugen-Hypoxia Rat Is Still "the One:" A Model of Group 1 Pulmonary Hypertension: Reply to Le Cras and Abman.

Am J Respir Crit Care Med. 2020 Mar 1;201(5):621-624. doi: 10.1164/rccm.201910-1983LE.PMID: 31769697 Free PMC article. No abstract available.

 

Bojkova D, Bechtel M, McLaughlin KM, McGreig JE, Klann K, Bellinghausen C, Rohde G, Jonigk D, Braubach P, Ciesek S, Münch C, Wass MN, Michaelis M, Cinatl J Jr.

Aprotinin Inhibits SARS-CoV-2 Replication.

Cells. 2020 Oct 30;9(11):2377. doi: 10.3390/cells9112377.PMID: 33143316 

 

Bork T, Liang W, Yamahara K, Lee P, Tian Z, Liu S, Schell C, Thedieck K, Hartleben B, Patel K, Tharaux PL, Lenoir O, Huber TB.

Podocytes maintain high basal levels of autophagy independent of mtor signaling.

Autophagy. 2020 Nov;16(11):1932-1948. doi: 10.1080/15548627.2019.1705007. Epub 2019 Dec 23.PMID: 31865844

 

Bormann T, Maus R, Stolper J, Jonigk D, Welte T, Gauldie J, Kolb MR, Maus UA.

Role of the COX2-PGE2 axis in S. pneumoniae induced exacerbation of experimental fibrosis.

Am J Physiol Lung Cell Mol Physiol. 2020 Dec 9. doi: 10.1152/ajplung.00024.2020. Online ahead of print.PMID: 33296268

 

Calabrese F, Schiavon M, Perissinotto E, Lunardi F, Marulli G, Di Gregorio G, Pezzuto F, Edith Vuljan S, Forin E, Wiegmann B, Jonigk D, Warnecke G, Rea F.

Organ Care System Lung resulted in lower apoptosis and iNOS expression in donor lungs.

Am J Transplant. 2020 Dec;20(12):3639-3648. doi: 10.1111/ajt.16187. Epub 2020 Sep 3.PMID: 32652873

 

Christgen M, Bartels S, van Luttikhuizen JL, Bublitz J, Rieger LU, Christgen H, Stark H, Sander B, Lehmann U, Steinemann D, Derksen PWB, Kreipe H.

E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements.

Mod Pathol. 2020 Dec;33(12):2483-2498. doi: 10.1038/s41379-020-0591-3. Epub 2020 Jun 22.PMID: 32572153 Free PMC article.

 

Christgen M, Gluz O, Harbeck N, Kates RE, Raap M, Christgen H, Clemens M, Malter W, Nuding B, Aktas B, Kuemmel S, Reimer T, Stefek A, Krabisch P, Just M, Augustin D, Graeser M, Baehner F, Wuerstlein R, Nitz U, Kreipe H; West German Study Group PlanB Investigators.

Differential impact of prognostic parameters in hormone receptor-positive lobular breast cancer.

Cancer. 2020 Nov 15;126(22):4847-4858. doi: 10.1002/cncr.33104. Epub 2020 Aug 11.PMID: 32780421

 

Danov O, Wolff M, Bartel S, Böhlen S, Obernolte H, Wronski S, Jonigk D, Hammer B, Kovacevic D, Reuter S, Krauss-Etschmann S, Sewald K.

Cigarette Smoke Affects Dendritic Cell Populations, Epithelial Barrier Function, and the Immune Response to Viral Infection With H1N1.

Front Med (Lausanne). 2020 Nov 6;7:571003. doi: 10.3389/fmed.2020.571003. eCollection 2020.PMID: 33240904 Free PMC article.

 

Delgado SJ, Dehmel S, Twisterling E, Wichmann J, Jonigk D, Warnecke G, Braubach P, Fieguth HG, Wilkens L, Dahlmann F, Kaup FJ, Eggel A, Knauf S, Sewald K, Braun A.

Disruptive anti-IgE Inhibitors Prevent Mast Cell–Dependent Early Airway Response in Viable Atopic Lung Tissue.

J Allergy Clin Immunol. 2020 Feb;145(2):719-722.e1. doi: 10.1016/j.jaci.2019.11.002. Epub 2019 Dec 16.PMID: 31858993 No abstract available.

 

Derben FC, Engel B, Zachou K, Hartl J, Hartleben B, Bantel H, Schramm C, Dalekos GN, Manns MP, Jaeckel E, Taubert R.

CK-18 cell death markers improve the prediction of histological remission in autoimmune hepatitis during biochemical remission.

Liver Int. 2021 Jan;41(1):123-127. doi: 10.1111/liv.14699.PMID: 33043565

 

Derlin T, Jaeger B, Jonigk D, Apel R, Freise J, Shin HO, Weiberg D, Warnecke G, Ross TL, Wester HJ, Seeliger B, Welte T, Bengel FM, Prasse A.

Clinical Molecular Imaging of Pulmonary CXCR4 Expression to Predict Outcome of Pirfenidone Treatment in Idiopathic Pulmonary Fibrosis.

Chest. 2020 Aug 19:S0012-3692(20)34229-X. doi: 10.1016/j.chest.2020.08.2043. Online ahead of print.PMID: 32822674

 

Derlin T, Werner RA, Lafos M, Henkenberens C, von Klot C AJ, Sommerlath Sohns J, Ross TL, Bengel FM. 

Neuroendocrine Differentiation and Response to PSMA-Targeted Radioligand Therapy in Advanced Metastatic Castration-Resistant Prostate Cancer: a Single-Center Retrospective Study.

J Nucl Med. 2020 Mar 13;doi: 10.2967/jnumed.120.241588. Online ahead of print.

 

Ditsch N, Untch M, Kolberg-Liedtke C, Jackisch C, Krug D, Friedrich M, Janni W, Müller V, Albert US, Banys-Paluchowski M, Bauerfeind I, Blohmer JU, Budach W, Dall P, Diel I, Fallenberg EM, Fasching PA, Fehm T, Gerber B, Gluz O, Hanf V, Harbeck N, Heil J, Huober J, Kreipe HH, Kühn T, Kümmel S, Loibl S, Lüftner D, Lux M, Maass N, Moebus V, Mundhenke C, Park-Simon TW, Reimer T, Rhiem K, Rody A, Schmidt M, Schneeweiss A, Solbach C, Solomayer EF, Stickeler E, Thomssen C, Witzel I, Wöckel A, Thill M.

AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2020.

Breast Care (Basel). 2020 Jun;15(3):294-309. doi: 10.1159/000508736. Epub 2020 Jun 10.PMID: 32774225 Free article. Review. No abstract available.

 

Donnert M, Elsheikh S, Arce-Rodriguez A, Pawar V, Braubach PJonigk D, Haverich A, Weiss S, Müsken M, Häussler S.

Targeting bioenergetics is key to counteracting the drug-tolerant state of biofilm-grown bacteria.

PLoS Pathog. 2020 Dec 22;16(12):e1009126. doi: 10.1371/journal.ppat.1009126. Online ahead of print.PMID: 33351859

 

Dowsett M, Ellis MJ, Dixon JM, Gluz O, Robertson J, Kates R, Suman VJ, Turnbull AK, Nitz U, Christgen MKreipe H, Kuemmel S, Bliss JM, Barry P, Johnston SR, Jacobs SA, Ma CX, Smith IE, Harbeck N.

Evidence-based guidelines for managing patients with primary ER+ HER2- breast cancer deferred from surgery due to the COVID-19 pandemic.

NPJ Breast Cancer. 2020 Jun 8;6:21. doi: 10.1038/s41523-020-0168-9. eCollection 2020.PMID: 32550266 Free PMC article.

 

Dywicki J, Buitrago-Molina LE, Pietrek J, Lieber M, Broering R, Khera T, Schlue J, Manns MP, Wedemeyer H, Jaeckel E, Hardtke-Wolenski M. 

Autoimmune hepatitis induction can occur in the liver.

Liver Int. 2020 Feb;40(2):377-381. doi: 10.1111/liv.14296. Epub 2019 Dec 1.PMID: 31724273

 

Eckermann M, Frohn J, Reichardt M, Osterhoff M, Sprung M, Westermeier F, Tzankov A, Werlein C, Kühnel MJonigk D, Salditt T.

3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomography.

Elife. 2020 Aug 20;9:e60408. doi: 10.7554/eLife.60408.PMID: 32815517 Free PMC article.

 

Ernst P, Engmann B, Frietsch JJ, Schnetzke U, Scholl S, Theis B, Kreipe HH, Ernst T, Glaser A, Haferlach T, Koch T, Hochhaus A, Hilgendorf I.

A 19-year-old patient with atypical chronic myeloid leukemia.

Ann Hematol. 2020 May;99(5):1145-1148. doi: 10.1007/s00277-020-03992-w. Epub 2020 Mar 19.PMID: 32193626 Free PMC article. No abstract available.

 

Feist H, Hussein K, Blöcker T, Wohlschlaeger J. 

Pathoanatomical Lesions in Placentas With Excessively Hypercoiled Umbilical Cords: Frequent Detection of Massive Perivillous Fibrin Deposition.

Pediatr Dev Pathol. 2020 Mar-Apr;23(2):107-114. doi: 10.1177/1093526619865426. Epub 2019 Jul 25.PMID: 31345137

 

Feist H, Hussein K, Stucki-Koch A, Wohlschlaeger J, Hager T, Blöcker T, Heim A. 

Villitis of unknown etiology and chronic deciduitis are not associated with human papilloma virus and enterovirus infection.

Virchows Arch. 2020 Feb 5. doi: 10.1007/s00428-020-02765-0. Online ahead of print.

 

Fleißner F, Tudorache I, Christgen M, Cebotari S.

Cardiac Phlegmon: Infectious Endocarditis Causing Ventricular Wall Rupture.

Thorac Cardiovasc Surg Rep. 2020 Jan;9(1):e51-e54. doi: 10.1055/s-0040-1716391. Epub 2020 Nov 2.PMID: 33154880 Free PMC article.

 

Gambichler T, Doerler M, Nöpel-Dünnebacke S, Matschke J, Bräsen JH, Linke RP, Susok L. 

Haemorrhagic bullous lesions in cutaneous light-chain amyloidosis with smouldering myeloma.

J Eur Acad Dermatol Venereol. 2020 Jan;34(1):e13-e15. doi: 10.1111/jdv.15844. Epub 2019 Aug 30.PMID: 31390676 No abstract available.

 

Gleitz HFE, Dugourd AJF, Leimkühler NB, Snoeren IAM, Fuchs SNR, Menzel S, Ziegler S, Kröger N, Triviai I, Büsche GKreipe H, Banjanin B, Pritchard JE, Hoogenboezem R, Bindels EM, Schumacher N, Rose-John S, Elf S, Saez-Rodriguez J, Kramann R, Schneider RK.

Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN.

Blood. 2020 Oct 29;136(18):2051-2064. doi: 10.1182/blood.2019004095.PMID: 32726410 Free PMC article.

 

Gluz O, Kolberg-Liedtke C, Prat A, Christgen M, Gebauer D, Kates R, Paré L, Grischke EM, Forstbauer H, Braun M, Warm M, Hackmann J, Uleer C, Aktas B, Schumacher C, Kuemmel S, Wuerstlein R, Pelz E, Nitz U, Kreipe HH, Harbeck N.

Efficacy of deescalated chemotherapy according to PAM50 subtypes, immune and proliferation genes in triple-negative early breast cancer: Primary translational analysis of the WSG-ADAPT-TN trial.

Int J Cancer. 2020 Jan 1;146(1):262-271. doi: 10.1002/ijc.32488. Epub 2019 Jun 19.PMID: 31162838 Free article. Clinical Trial.

 

Greer M, Werlein C, Jonigk D

Surveillance for acute cellular rejection after lung transplantation.

Ann Transl Med. 2020 Mar;8(6):410. doi: 10.21037/atm.2020.02.127.PMID: 32355854 Free PMC article. Review.

 

Greite R, Derlin K, Hensen B, Thorenz A, Rong S, Chen R, Hellms S, Jang MS, Bräsen JH, Meier M, Willenberg I, Immenschuh S, Haller H, Luft FC, Panigrahy D, Hwang SH, Hammock BD, Schebb NH, Gueler F.

Early antihypertensive treatment and ischemia-induced acute kidney injury.

Am J Physiol Renal Physiol. 2020 Oct 1;319(4):F563-F570. doi: 10.1152/ajprenal.00078.2020. Epub 2020 Aug 17.PMID: 32799675

 

Greunz EM, Lemberger K, Catinaud J, Chenet B, Linke RP, Bräsen JH, Schmitz J, Bertelsen MF. 

Amyloidosis in Caracals (Caracal Caracal).

J Zoo Wildl Med. 2020 Mar 17;51(1):202-209. doi: 10.1638/2019-0005.PMID: 32212564

 

Griguolo G, Brasó-Maristany F, González-Farré B, Pascual T, Chic N, Saurí T, Kates R, Gluz O, Martínez D, Paré L, Tsvetkova V, Pesantez D, Vidal M, Adamo B, Muñoz M, Galván P, Barberá L, Cuatrecasas M, Christgen MKreipe H, Monge-Escartín I, Villagrasa P, Soy D, Giarratano T, Dieci MV, Conte P, Harbeck N, Guarneri V, Prat A.

ERBB2 mRNA Expression and Response to Ado-Trastuzumab Emtansine (T-DM1) in HER2-Positive Breast Cancer.

Cancers (Basel). 2020 Jul 14;12(7):1902. doi: 10.3390/cancers12071902.PMID: 32674482 Free PMC article.

 

Haake K, Neehus A-L , Buchegger T, Kühnel MP, Blank P, Philipp F, Oleaga-Quintas C, Schulz A, Grimley M, Goethe R, Jonigk D, Kalinke U, Boisson-Dupuis S, Casanova J-L , Bustamante J, Lachmann N. 

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.

Cells. 2020 Feb 19;9(2):483. doi: 10.3390/cells9020483.PMID: 32093117 Free PMC article.

 

Hack T, Bertram S, Blair H, Börger V, Büsche G, Denson L, Fruth E, Giebel B, Heidenreich O, Klein-Hitpass L, Kollipara L, Sendker S, Sickmann A, Walter C, von Neuhoff N, Hanenberg H, Reinhardt D, Schneider M, Rasche M.

Exposure of Patient-Derived Mesenchymal Stromal Cells to TGFB1 Supports Fibrosis Induction in a Pediatric Acute Megakaryoblastic Leukemia Model.

Mol Cancer Res. 2020 Oct;18(10):1603-1612. doi: 10.1158/1541-7786.MCR-20-0091. Epub 2020 Jul 8.PMID: 32641517

 

Hacker KS, Jansson K, Pichler J, Salman J, Avsar M, Siemeni T, Knöfel AK, Höffler K, Gottlieb J, Frühauf J, Werner M, Poyanmehr R, Jonigk D, Balzer MS, Hewicker-Trautwein M, Haverich A, Sommer W, Warnecke G.

Delayed non-myeloablative irradiation to induce long-term allograft acceptance in a large animal lung transplantation model.

Transpl Immunol. 2020 Oct 27:101350. doi: 10.1016/j.trim.2020.101350. Online ahead of print.PMID: 33127498

 

Hagner M, Albrecht M, Guerra M, Braubach P, Halle O, Zhou-Suckow Z, Butz S, Jonigk D, Hansen G, Schultz C, Dittrich AM, Mall MA.

IL-17A from innate and adaptive lymphocytes contributes to inflammation and damage in cystic fibrosis lung disease.

Eur Respir J. 2020 Dec 10:1900716. doi: 10.1183/13993003.00716-2019. Online ahead of print.PMID: 33303549

 

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Hübscher SG, Manns MP, Jaeckel E, Taubert R.

DSA are associated with more graft injury, more fibrosis, and upregulation of rejection-associated transcripts in subclinical rejection.

Transplantation. 2020 Mar;104(3):551-561. doi: 10.1097/TP.0000000000003034.PMID: 31651790

 

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Manns MP, Jaeckel E, Taubert R.

Non-invasive screening for subclinical liver graft injury in adults via donor-specific anti-HLA antibodies.

Sci Rep. 2020 Aug 28;10(1):14242. doi: 10.1038/s41598-020-70938-7.PMID: 32859929 Free PMC article.

 

Jayaprakash S, Le LTM, Sander B, Golas MM.

Expression of the Neural REST/NRSF-SIN3 Transcriptional Corepressor Complex as a Target for Small-Molecule Inhibitors.

Mol Biotechnol. 2020 Nov 1. doi: 10.1007/s12033-020-00283-7. Online ahead of print.PMID: 33130996

 

Jöhrens K, von Wasielewski R, Kreipe HH, Forberger A, Jurmeister P, Dietel M, Stenzinger A, Fischer J.

[Quality assurance in diagnostic in situ hybridization-experience of QuIP].

Pathologe. 2020 Nov;41(6):614-620. doi: 10.1007/s00292-020-00832-6.PMID: 32945916 Review. German.

 

Jonigk D, Märkl B, Helms J.

COVID-19: what the clinician should know about post-mortem findings.

Intensive Care Med. 2021 Jan;47(1):86-89. doi: 10.1007/s00134-020-06302-0. Epub 2020 Nov 3.PMID: 33141245 Free PMC article. No abstract available.

 

Kanzelmeyer NK, Lerch C, Ahlenstiel-Grunow T, Bräsen JH, Haffner D, Pape L.

The role of protocol biopsies after pediatric kidney transplantation.

Medicine (Baltimore). 2020 Jun 5;99(23):e20522. doi: 10.1097/MD.0000000000020522.PMID: 32502003 Free PMC article.

 

Kamp JC, Jonigk DD, Hinrichs JB, Hoeper MM, Schönhofer B, Ernst D, Welte T, Suhling H.

Recurrent Life-threatening Pneumonitis in a 37-Year-Old Woman.

Chest. 2020 Sep;158(3):e127-e132. doi: 10.1016/j.chest.2020.03.066.PMID: 32892889

 

Kim EL , Sorokin M, Kantelhardt SR, Kalasauskas D, Sprang B, Fauss J, Ringel F, Garazha A, Albert E, Gaifullin N, Hartmann C, Naumann N, Bikar SE, Giese A, Buzdin A. 

Intratumoral heterogeneity and longitudinal changes in gene expression predict differential drug sensitivity in newly diagnosed and recurrent glioblastoma.

Cancers (Basel). 2020 Feb 24;12(2):520. doi: 10.3390/cancers12020520.PMID: 32102350 Free PMC article.

 

Kirchner M, Glade J, Lehmann U, Merkelbach-Bruse S, Hummel M, Lehmann A, Trautmann M, Kumbrink J, Jung A, Dietmaier W, Endris V, Kazdal D, Ploeger C, Evert M, Horst D, Kreipe H, Kirchner T, Wardelmann E, Büttner R, Weichert W, Dietel M, Schirmacher P, Stenzinger A, Pfarr N. 

NTRK testing: First results of the QuiP-EQA scheme and a comprehensive map of NTRK fusion variants and their diagnostic coverage by targeted RNA-based NGS assays.

Genes Chromosomes Cancer. 2020 Apr 22. doi: 10.1002/gcc.22853. Online ahead of print.

 

Kolberg-Liedtke C, Gluz O, Heinisch F, Feuerhake FKreipe H, Clemens M, Nuding B, Malter W, Reimer T, Wuerstlein R, Graeser M, Shak S, Nitz U, Kates R, Christgen M, Harbeck N.

Association of TILs with clinical parameters, Recurrence Score® results, and prognosis in patients with early HER2-negative breast cancer (BC)-a translational analysis of the prospective WSG PlanB trial.

Breast Cancer Res. 2020 May 14;22(1):47. doi: 10.1186/s13058-020-01283-w.PMID: 32408905 Free PMC article.

 

Kommoss FKF, Schwab C, Tavernar L, Schreck J, Wagner WL, Merle U, Jonigk D, Schirmacher P, Longerich T.

The Pathology of Severe COVID-19-Related Lung Damage.

Dtsch Arztebl Int. 2020 Jul 20;117(29-30):500-506. doi: 10.3238/arztebl.2020.0500.PMID: 32865490 Free PMC article.

 

Kreimann K, Jang MS, Rong S, Greite R, von Vietinghoff S, Schmitt R, Bräsen JH, Schiffer L, Gerstenberg J, Vijayan V, Dittrich-Breiholz O, Wang L, Karsten CM, Gwinner W, Haller H, Immenschuh S, Gueler F.

Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation.

Front Immunol. 2020 Aug 6;11:1204. doi: 10.3389/fimmu.2020.01204. eCollection 2020.PMID: 32849490 Free PMC article.

 

Länger F, Werlein C, Soudah B, Schwerk N, Jonigk D.

[Interstitial lung disease in infancy and early childhood].

Pathologe. 2020 Dec 23:1-10. doi: 10.1007/s00292-020-00884-8. Online ahead of print.PMID: 33355705 Free PMC article. Review. German.

 

Lehner GM, Schacht V, Angela Y, Satzger I, Gutzmer R.

Erfolgreiche Behandlung eines metastasierenden Melanoms mit Talimogen laherparepvec (T-VEC) bei einer lebertransplantierten Patientin.

J Dtsch Dermatol Ges. 2020 Dec;18(12):1495-1497. doi: 10.1111/ddg.14284_g.PMID: 33373132 German. No abstract available.

 

Leimkühler NB, Gleitz HFE, Ronghui L, Snoeren IAM, Fuchs SNR, Nagai JS, Banjanin B, Lam KH, Vogl T, Kuppe C, Stalmann USA, Büsche GKreipe H, Gütgemann I, Krebs P, Banz Y, Boor P, Tai EW, Brümmendorf TH, Koschmieder S, Crysandt M, Bindels E, Kramann R, Costa IG, Schneider RK.

Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.

Cell Stem Cell. 2020 Dec 9:S1934-5909(20)30542-7. doi: 10.1016/j.stem.2020.11.004. Online ahead of print.PMID: 33301706 Free article.

 

Mayer U, Schmitz J, Bräsen JH, Pape L. 

Crescentic glomerulonephritis in children.

Pediatr Nephrol. 2020 May;35(5):829-842. doi: 10.1007/s00467-019-04436-y. Epub 2020 Feb 12.PMID: 32052153 Free PMC article.

 

Mederacke YS, Nienen M, Jarek M, Geffers R, Hupa-Breier K, Babel N, Reinke P, Mederacke I, Rudolf Vondran FW, Jonigk D, Wedemeyer H, Jaeckel E.

T cell receptor repertoires within liver allografts are different to those in the peripheral blood.

J Hepatol. 2020 Dec 18:S0168-8278(20)33887-3. doi: 10.1016/j.jhep.2020.12.014. Online ahead of print.PMID: 33347951

 

Melchert J, Henningfeld KA, Richts S, Lingner T, Jonigk D, Pieler T. 

The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus.

Dev Biol. 2020 Mar 15;459(2):138-148. doi: 10.1016/j.ydbio.2019.12.007. Epub 2019 Dec 14.PMID: 31846624

 

Mishra A, Emamgholi F, Erlangga Z, Hartleben B, Unger K, Wolff K, Teichmann U, Kessel M, Woller N, Kühnel F, Dow LE, Manns MP, Vogel A, Lowe SW, Saborowski A, Saborowski M. 

Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing.

Carcinogenesis. 2020 May 14;41(3):334-344. doi: 10.1093/carcin/bgz108.PMID: 31170286

 

Mund E, Salem J, Kreipe HH, Hussein K.

Clinically latent and autopsy-verified inflammatory disorders and malignant tumours in transplant patients.

J Clin Pathol. 2020 Dec 28:jclinpath-2020-207080. doi: 10.1136/jclinpath-2020-207080. Online ahead of print.PMID: 33372107

 

Mynarek M, von Hoff K, Pietsch T, Ottensmeier H, Warmuth-Metz M, Bison B, Pfister S, Korshunov A, Sharma T, Jaeger N, Ryzhova M, Zheludkova O, Golanov A, Rushing EJ, Hasselblatt M, Koch A, Schüller U, von Deimling A, Sahm F, Sill M, Riemenschneider MJ, Dohmen H, Monoranu CM, Sommer C, Staszewski O, Mawrin C, Schittenhelm J, Brück W, Filipski K, Hartmann C, Meinhardt M, Pietschmann K, Haberler C, Slavc I, Gerber NU, Grotzer M, Benesch M, Schlegel PG, Deinlein F, von Bueren AO, Friedrich C, Juhnke BO, Obrecht D, Fleischhack G, Kwiecien R, Faldum A, Kortmann RD, Kool M, Rutkowski S. 

Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort.

J Clin Oncol. 2020 Apr 24;JCO1903057. doi: 10.1200/JCO.19.03057. Online ahead of print.

 

Neubert L, Borchert P, Stark H, Hoefer A, Vogel-Claussen J, Warnecke G, Eubel H, Kuenzler P, Kreipe HH, Hoeper MM, Kuehnel M, Jonigk D

Molecular Profiling of Vascular Remodeling in Chronic Pulmonary Disease.

Am J Pathol. 2020 Apr 7;S0002-9440(20)30145-0. doi: 10.1016/j.ajpath.2020.03.008. Online ahead of print.

 

Niehues T, Özgür TT, Bickes M, Waldmann R, Schöning J, Bräsen J, Hagel C, Ballmaier M, Klusmann JH, Niedermayer A, Pannicke U, Enders A, Dückers G, Siepermann K, Hempel J, Schwarz K, Viemann D.

Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pre-excitation syndrome.

Eur J Immunol. 2020 Mar 17. doi: 10.1002/eji.201948504. Online ahead of print.

 

Nitz U, Gluz O, Kreipe HH, Christgen M, Kuemmel S, Baehner FL, Shak S, Aktas B, Braun M, Lüdtke-Heckenkamp K, Forstbauer H, Grischke EM, Nuding B, Darsow M, Schumacher C, Krauss K, Malter W, Thill M, Warm M, Wuerstlein R, Kates RE, Harbeck N.

The run-in phase of the prospective WSG-ADAPT HR+/HER2- trial demonstrates the feasibility of a study design combining static and dynamic biomarker assessments for individualized therapy in early breast cancer.

Ther Adv Med Oncol. 2020 Nov 23;12:1758835920973130. doi: 10.1177/1758835920973130. eCollection 2020.PMID: 33281950 Free PMC article.

 

Noske A, Ammann JU, Wagner DC, Denkert C, Lebeau A, Sinn P, Kreipe HH, Sommer U, Baretton G, Steiger K, Kiechle M, Hieke-Schulz S, Flores M, Roth W, Weichert W. 

A multicentre analytical comparison study of inter-reader and inter-assay agreement of four programmed death-ligand 1 immunohistochemistry assays for scoring in triple-negative breast cancer.

Histopathology. 2020 Sep 16. doi: 10.1111/his.14254. Online ahead of print.PMID: 32936950

 

Pfarr N, Kirchner M, Lehmann U, Leichsenring J, Merkelbach-Bruse S, Glade J, Hummel M, Stögbauer F, Lehmann A, Trautmann M, Kumbrink J, Jung A, Dietmaier W, Endris V, Kazdal D, Evert M, Horst D, Kreipe H, Kirchner T, Wardelmann E, Lassen U, Büttner R, Weichert W, Dietel M, Schirmacher P, Stenzinger A. 

Testing NTRK testing: Wet-lab and in silico comparison of RNA-based targeted sequencing assays.

Genes Chromosomes Cancer. 2020 Mar;59(3):178-188. doi: 10.1002/gcc.22819. Epub 2019 Nov 18.PMID: 31652375

 

Reifenrath J, Janßen HC, Warwas DP, Kietzmann M, Behrens P, Willbold E, Fedchenko M, Angrisani N.

Implant-based direction of magnetic nanoporous silica nanoparticles - influence of macrophage depletion and infection.

Nanomedicine. 2020 Nov;30:102289. doi: 10.1016/j.nano.2020.102289. Epub 2020 Aug 26.PMID: 32861030

 

Roy-Chowdhury E, Brauns N, Helmke A, Nordlohne J, Bräsen JH, Schmitz J, Volkmann J, Fleig SV, Kusche-Vihrog K, Haller H, von Vietinghoff S.

Human CD16+ monocytes promote a pro-atherosclerotic endothelial cell phenotype via CX3CR1-CX3CL1 interaction.

Cardiovasc Res. 2020 Jul 27:cvaa234. doi: 10.1093/cvr/cvaa234. Online ahead of print.PMID: 32717023

 

Saborowski A, Lehmann U, Vogel A.

FGFR inhibitors in cholangiocarcinoma: what's now and what's next?

Ther Adv Med Oncol. 2020 Sep 16;12:1758835920953293. doi: 10.1177/1758835920953293. eCollection 2020.PMID: 32983265 Free PMC article. Review.

 

Schaadt NS, Schönmeyer R, Forestier G, Brieu N, Braubach P, Nekolla K, Meyer-Hermann M, Feuerhake F

Graph-based description of tertiary lymphoid organs at single-cell level.

PLoS Comput Biol. 2020 Feb 21;16(2):e1007385. doi: 10.1371/journal.pcbi.1007385. eCollection 2020 Feb.PMID: 32084130 Free PMC article.

 

Schirmer B, Rother T, Bruesch I, Bleich A, Werlein C, Jonigk D, Seifert R, Neumann D. 

Genetic deficiency of the histamine H4-receptor reduces experimental colorectal carcinogenesis in mice.

Cancers (Basel). 2020 Apr 8;12(4):912. doi: 10.3390/cancers12040912.PMID: 32276475 Free PMC article.

 

Schaumann NHussein K.

Hepatic and Adrenocortical Choristomas in the Placenta.

Fetal Pediatr Pathol. 2020 Jul 22:1-10. doi: 10.1080/15513815.2020.1792594. Online ahead of print.PMID: 32696693

 

Schimmel K, Jung M, Foinquinos A, José GS, Beaumont J, Bock K, Grote-Levi L, Xiao K, Bär C, Pfanne A, Just A, Zimmer K, Ngoy S, López B, Ravassa S, Samolovac S, Janssen-Peters H, Remke J, Scherf K, Dangwal S, Piccoli MT, Kleemiss F, Kreutzer FP, Kenneweg F, Leonardy J, Hobuß L, Santer L, Do QT, Geffers R, Braesen JH, Schmitz J, Brandenberger C, Müller DN, Wilck N, Kaever V, Bähre H, Batkai S, Fiedler J, Alexander KM, Wertheim BM, Fisch S, Liao R, Diez J, González A, Thum T.

Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction.

Circulation. 2020 Mar 3;141(9):751-767. doi: 10.1161/CIRCULATIONAHA.119.042559. Epub 2020 Jan 17.PMID: 31948273 Free PMC article.

 

Schirmer B, Rother T, Bruesch I, Bleich A, Werlein CJonigk D, Seifert R, Neumann D.

Genetic Deficiency of the Histamine H4-Receptor Reduces Experimental Colorectal Carcinogenesis in Mice.

Cancers (Basel). 2020 Apr 8;12(4):912. doi: 10.3390/cancers12040912.PMID: 32276475 Free PMC article.

 

Schünemann C, Göhring G, Behrens YL, Kreipe HH, Ganser A, Thol F.

Histiocytic sarcoma progressing from follicular lymphoma and mimicking acquired hemophagocytic lymphohistiocytosis.

Ann Hematol. 2020 Oct;99(10):2441-2443. doi: 10.1007/s00277-020-04190-4. Epub 2020 Aug 17.PMID: 32808104 Free PMC article. No abstract available.

 

Schweizer L, Thierfelder F, Thomas C, Soschinski P, Suwala A, Stichel D, Wefers AK, Wessels L, Misch M, Kim HY, Jödicke R, Teichmann D, Kaul D, Kahn J, Bockmayr M, Hasselblatt M, Younsi A, Unterberg A, Knie B, Walter J, Al Safatli D, May SA, Jödicke A, Ntoulias G, Moskopp D, Vajkoczy P, Heppner FL, Capper D, Hartmann W, Hartmann C, von Deimling A, Reuss DE, Schöler A, Koch A.

Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity.

Acta Neuropathol. 2020 Dec;140(6):893-906. doi: 10.1007/s00401-020-02218-7. Epub 2020 Sep 14.PMID: 32926213 Free PMC article.

 

Sen P, Helmke A, Liao CM, Sörensen-Zender I, Rong S, Bräsen JH, Melk A, Haller H, von Vietinghoff S, Schmitt R. 

SerpinB2 Regulates Immune Response in Kidney Injury and Aging.

J Am Soc Nephrol. 2020 May;31(5):983-995. doi: 10.1681/ASN.2019101085. Epub 2020 Mar 24.PMID: 32209589

 

Serth J, Peters I, Dubrowinskaja N, Reese C, Albrecht K, Klintschar M, Lafos M, Grote A, Becker A, Hennenlotter J, Stenzl A, Tezval H, Kuczyk MA. 

Age-, tumor-, and metastatic tissue-associated DNA hypermethylation of a T-box brain 1 locus in human kidney tissue.

Clin Epigenetics. 2020 Feb 18;12(1):33. doi: 10.1186/s13148-020-0823-x.PMID: 32070431 Free PMC article.

 

Sievers P, Sill M, Blume C, Tauziede-Espariat A, Schrimpf D, Stichel D, Reuss DE, Dogan H, Hartmann C, Mawrin C, Hasselblatt M, Stummer W, Schick U, Hench J, Frank S, Ketter R, Schweizer L, Schittenhelm J, Puget S, Brandner S, Jaunmuktane Z, Küsters B, Abdullaev Z, Pekmezci M, Snuderl M, Ratliff M, Herold-Mende C, Unterberg A, Aldape K, Ellison DW, Wesseling P, Reifenberger G, Wick W, Perry A, Varlet P, Pfister SM, Jones DTW, von Deimling A, Sahm F; German Consortium “Aggressive Meningiomas”.

Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1.

Acta Neuropathol. 2020 Dec 14. doi: 10.1007/s00401-020-02247-2. Online ahead of print.PMID: 33319313

 

Sieweke J-T, Akin M, Stetskamp S, Riehle C, Jonigk D, Flierl U, Pfeffer TJ, Hirsch V, Dutzmann J, Hoeper MM, Kühn C, Bauersachs J, Schäfer A. 

Mechanical Circulatory Support in Refractory Cardiogenic Shock due to Influenza Virus-Related Myocarditis.

Eur Respir J. 2020 May 12;2000925. doi: 10.1183/13993003.00925-2020. Online ahead of print.

 

Slabik C, Kalbarczyk M, Danisch S, Zeidler R, Klawonn F, Volk V, Krönke NFeuerhake F, Ferreira de Figueiredo C, Blasczyk R, Olbrich H, Theobald SJ, Schneider A, Ganser A, von Kaisenberg C, Lienenklaus S, Bleich A, Hammerschmidt W, Stripecke R.

CAR-T Cells Targeting Epstein-Barr Virus gp350 Validated in a Humanized Mouse Model of EBV Infection and Lymphoproliferative Disease.

Mol Ther Oncolytics. 2020 Aug 8;18:504-524. doi: 10.1016/j.omto.2020.08.005. eCollection 2020 Sep 25.PMID: 32953984 Free PMC article.

 

Soudah B.

Metastasen in der Leber.

CYTO-INFO. 2020; 3: 79-85

 

Soudah B, Oberndörfer AK.

Zytologie der Speicheldrüsen mit Differentialdignosen.

CYTO-INFO. 2020; 1: 125-131

 

Stahl K, Bräsen JH, Hoeper MM, David S.

Direct evidence of SARS-CoV-2 in gut endothelium.

Intensive Care Med. 2020 Nov;46(11):2081-2082. doi: 10.1007/s00134-020-06237-6. Epub 2020 Sep 11.PMID: 32915253 Free PMC article. No abstract available.

 

Stauss RD, Grosse GM, Neubert L, Falk CS, Jonigk D, Kühnel MP, Gabriel MM, Schuppner R, Lichtinghagen R, Wilhelmi M, Weissenborn K, Schrimpf C.

Distinct systemic cytokine networks in symptomatic and asymptomatic carotid stenosis.

Sci Rep. 2020 Dec 15;10(1):21963. doi: 10.1038/s41598-020-78941-8.PMID: 33319833 Free PMC article.

 

Stenzinger A, van Tilburg CM, Tabatabai G, Länger F, Graf N, Griesinger F, Heukamp LC, Hummel M, Klingebiel T, Hettmer S, Vokuhl C, Merkelbach-Bruse S, Overkamp F, Reichardt P, Scheer M, Weichert W, Westphalen CB, Bokemeyer C, Ivanyi P, Loges S, Schirmacher P, Wörmann B, Bielack S, Seufferlein TTW.

[Diagnosis and therapy of tumors with NTRK gene fusion].

Pathologe. 2020 Nov 30. doi: 10.1007/s00292-020-00864-y. Online ahead of print.PMID: 33258061 Review. German.

 

Struck AK, Klotz D, Hülskötter K, Wohlsein P, Schmitz JBräsen JH, Distl O.

Complex segregation analysis of familial amyloidosis in Oriental shorthair cats.

Vet J. 2020 Nov;265:105552. doi: 10.1016/j.tvjl.2020.105552. Epub 2020 Oct 1.PMID: 33129552

 

Struck JP, Kramer MW, Katzendorn O, Hupe MC, Ozimek T, Hennig MJP, Wießmeyer JR, von Klot CAJ, Kuczyk MA, Kreipe HH, Merseburger AS, Perner S, Dressler FF.

Bicentric Retrospective Analysis of en Bloc Resection and Muscularis Mucosae Detection Rate in Non-Muscle Invasive Bladder Tumors: A Real-World Scenario.

Adv Ther. 2020 Oct 22. doi: 10.1007/s12325-020-01529-1. Online ahead of print.PMID: 33094476

 

Suwala AK, Stichel D, Schrimpf D, Kloor M, Wefers AK, Reinhardt A, Maas SLN, Kratz CP, Schweizer L, Hasselblatt M, Snuderl M, Abedalthagafi MSJ, Abdullaev Z, Monoranu CM, Bergmann M, Pekrun A, Freyschlag C, Aronica E, Kramm CM, Hinz F, Sievers P, Korshunov A, Kool M, Pfister SM, Sturm D, Jones DTW, Wick W, Unterberg A, Hartmann C, Dodgshun A, Tabori U, Wesseling P, Sahm F, von Deimling A, Reuss DE.

Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.

Acta Neuropathol. 2021 Jan;141(1):85-100. doi: 10.1007/s00401-020-02243-6. Epub 2020 Nov 20.PMID: 33216206

 

Szepes M, Melchert A, Dahlmann J, Hegermann J, Werlein CJonigk D, Haverich A, Martin U, Olmer R, Gruh I.

Dual Function of iPSC-Derived Pericyte-Like Cells in Vascularization and Fibrosis-Related Cardiac Tissue Remodeling In Vitro.

Int J Mol Sci. 2020 Nov 25;21(23):8947. doi: 10.3390/ijms21238947.PMID: 33255686 Free PMC article.

 

Thiele T, Seeliger T, Witte T, Sander B, Skripuletz T, Ernst D.

[Severe polyneuropathy in primary Sjögren's syndrome : Sjögren's syndrome should be considered in patients with motor neuropathy].

Z Rheumatol. 2020 Sep;79(7):707-709. doi: 10.1007/s00393-020-00821-3.PMID: 32474638 German.

 

Traidl S, Angela Y, Wedi B, Kapp A, Werfel T, Schacht V.

Langerhans cell histiocytosis mimicking prurigo nodularis.

J Eur Acad Dermatol Venereol. 2020 Oct 11. doi: 10.1111/jdv.16991. Online ahead of print.PMID: 33040393 No abstract available.

 

Tumpara S, Martinez-Delgado B, Gomez-Mariano G, Liu B, DeLuca DS, Korenbaum E, Jonigk D, Jugert F, Wurm FM, Wurm MJ, Welte T, Janciauskiene S.

The Delivery of α1-Antitrypsin Therapy Through Transepidermal Route: Worthwhile to Explore.

Front Pharmacol. 2020 Jul 3;11:983. doi: 10.3389/fphar.2020.00983. eCollection 2020.PMID: 32719598 Free PMC article.

 

Tzankov A, Jonigk D.

Unlocking the lockdown of science and demystifying COVID-19: how autopsies contribute to our understanding of a deadly pandemic.

Virchows Arch. 2020 Sep;477(3):331-333. doi: 10.1007/s00428-020-02887-5. Epub 2020 Jul 9.PMID: 32648040 Free PMC article. No abstract available.

 

Uecker M, Lehmann U, Braubach P, Schukfeh N, Madadi-Sanjani O, Ure BM, Petersen C, Kuebler JF.

Choledochal Cysts Resected during Childhood Show No Mutations of KRAS and BRAF as Early Markers of Malignancy in Cholangiocytes.

Eur J Pediatr Surg. 2020 Aug 20. doi: 10.1055/s-0040-1715610. Online ahead of print.PMID: 32820496

 

Van Alem CMA, Schmidbauer M, Rong S, Derlin K, Schmitz J, Bräsen JH, Thorenz A, Chen R, Ruben JM, Winter EM, Schilperoort M, Kooijman S, Lalai RA, Metselaar JM, Klemann C, Meier M, van Kooten C, Gueler F, Rotmans JI. 

Liposomal delivery improves the efficacy of prednisolone to attenuate renal inflammation in a mouse model of acute renal allograft rejection.

Transplantation. 2020 Apr;104(4):744-753. doi: 10.1097/TP.0000000000003060.PMID: 31929419 Free PMC article.

 

Verleden SE, Braubach P, Kuehnel M, Dickgreber N, Brouwer E, Tittmann P, Laenger F, Jonigk D.

Molecular approach to the classification of chronic fibrosing lung disease-there and back again.

Virchows Arch. 2020 Nov 9. doi: 10.1007/s00428-020-02964-9. Online ahead of print.PMID: 33169196 Review.

 

Verleden SE, Kirby M, Everaerts S, Vanstapel A, McDonough JE, Verbeken EK, Braubach P, Boone MN, Aslam D, Verschakelen J, Ceulemans LJ, Neyrinck AP, Van Raemdonck DE, Vos R, Decramer M, Hackett TL, Hogg JC, Janssens W, Verleden GM, Vanaudenaerde BM.

Small airway loss in the physiologically ageing lung: a cross-sectional study in unused donor lungs.

Lancet Respir Med. 2020 Oct 5:S2213-2600(20)30324-6. doi: 10.1016/S2213-2600(20)30324-6. Online ahead of print.PMID: 33031747

 

Verleden SE, Vanstapel A, De Sadeleer L, Weynand B, Boone M, Verbeken E, Piloni D, Van Raemdonck D, Ackermann M, Jonigk DD, Verschakelen J, Wuyts WA. 

Quantitative analysis of airway obstruction in lymphangio-leio-myomatosis.

Eur Respir J. 2020 Feb 27;1901965. doi: 10.1183/13993003.01965-2019. Online ahead of print.

 

Verleden SE, Von der Thüsen J, Roux A, Brouwers ES, Braubach P, Kuehnel M, Laenger F, Jonigk D

When tissue is the issue: A histological review of chronic lung allograft dysfunction.

Am J Transplant. 2020 Mar 17. doi: 10.1111/ajt.15864. Online ahead of print.

 

Viereck J, Bührke A, Foinquinos A, Chatterjee S, Kleeberger JA, Xiao K, Janssen-Peters H, Batkai S, Ramanujam D, Kraft T, Cebotari S, Gueler F, Beyer AM, Schmitz JBräsen JH, Schmitto JD, Gyöngyösi M, Löser A, Hirt MN, Eschenhagen T, Engelhardt S, Bär C, Thum T.

Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy.

Eur Heart J. 2020 Sep 21;41(36):3462-3474. doi: 10.1093/eurheartj/ehaa519.PMID: 32657324

 

Volkmann J, Schmitz J, Nordlohne J, Dong L, Helmke A, Sen P, Immenschuh S, Bernhardt WM, Gwinner W, Bräsen JH, Schmitt R, Haller H, von Vietinghoff S. 

Kidney injury enhances renal G-CSF expression and modulates granulopoiesis and human neutrophil CD177 in vivo..

Clin Exp Immunol. 2020 Jan;199(1):97-108. doi: 10.1111/cei.13372. Epub 2019 Sep 30.PMID: 31509227 Free PMC article.

 

von Stillfried S, Bülow RD, Röhrig R, Knüchel-Clarke R, Boor P; DeRegCOVID.

Autopsy registry can facilitate COVID-19 research.

EMBO Mol Med. 2020 Aug 7;12(8):e12885. doi: 10.15252/emmm.202012885. Epub 2020 Jul 3.PMID: 32559338 Free PMC article.

 

Watermann C, Pasternack H, Idel C, Ribbat-Idel J, Brägelmann J, Kuppler P, Offermann A, Jonigk D, Kühnel MP, Schröck A, Dreyer E, Rosero C, Nathansen J, Dubrovska A, Tharun L, Kirfel J, Wollenberg B, Perner S, Krupar R.

Recurrent HNSCC Harbor an Immunosuppressive Tumor Immune Microenvironment Suggesting Successful Tumor Immune Evasion.

Clin Cancer Res. 2020 Oct 27. doi: 10.1158/1078-0432.CCR-20-0197. Online ahead of print.PMID: 33109740

 

Weissinger EM, Metzger J, Schleuning M, Schmid C, Messinger D, Beutel G, Wagner-Drouet EM, Schetelig J, Baurmann H, Rank A, Stolzl F, Schäfer-Eckart K, Westphal K, Bethge W, von Harsdorf S, Bunjes DW, Heidenreich D, Klein S, Holler E, Kreipe HH, Jonigk D, Türüchanow I, Raad J, Papkalla A, von der Leyen H, Hambach L, Hamwi I, Ehrlich S, Krauter J, Stadler M, Ganser A.

A multicenter prospective, randomized, placebo-controlled phase II/III trial for preemptive acute graft-versus-host disease therapy.

Leukemia. 2020 Oct 20. doi: 10.1038/s41375-020-01059-3. Online ahead of print.PMID: 33082512

 

Werlein C, Seidel A, Warnecke G, Gottlieb J, Laenger F, Jonigk D

Lung Transplant Pathology: An Overview on Current Entities and Procedures.

Surg Pathol Clin. 2020 Mar;13(1):119-140. doi: 10.1016/j.path.2019.11.003.PMID: 32005428 Review.

 

Willers M, Ulas T, Völlger L, Vogl T, Heinemann AS, Pirr S, Pagel J, Fehlhaber B, Halle O, Schöning J, Schreek S, Löber U, Essex M, Hombach P, Graspeuntner S, Basic M, Bleich A, Cloppenborg-Schmidt K, Künzel S, Jonigk D, Rupp J, Hansen G, Förster R, Baines JF, Härtel C, Schultze JL, Forslund SK, Roth J, Viemann D.

S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants.

Gastroenterology. 2020 Dec;159(6):2130-2145.e5. doi: 10.1053/j.gastro.2020.08.019. Epub 2020 Aug 15.PMID: 32805279 Free article.

 

Yerabolu D, Weiss A, Kojonazarov B, Boehm M, Schlueter BC, Ruppert C, Günther A, Jonigk D, Grimminger F, Ghofrani HA, Seeger W, Weissmann N, Schermuly RT.

Targeting Jak-Stat Signaling in Experimental Pulmonary Hypertension.

Am J Respir Cell Mol Biol. 2021 Jan;64(1):100-114. doi: 10.1165/rcmb.2019-0431OC.PMID: 33052714

 

Yuzefovych Y, Valdivia E, Rong S, Hack F, Rother T, Schmitz J, Bräsen JH, Wedekind D, Moers C, Wenzel N, Gueler F, Blasczyk R, Figueiredo C.

Genetic Engineering of the Kidney to Permanently Silence MHC Transcripts During ex vivo Organ Perfusion.

Front Immunol. 2020 Feb 19;11:265. doi: 10.3389/fimmu.2020.00265. eCollection 2020.PMID: 32140158 Free PMC article.

 

 

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