Veröffentlichungen 2020

 

Ackermann M, Haake K, Kempf H, Kaschutnig P, Weiss A-C, Nguyen AH, Abeln M, Merkert S, Kühnel MP, Hartmann D, Jonigk D, Thum T, Kispert A, Milsom MD, Lachmann N. 

A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification.

Haematologica. 2020 Apr 23:haematol.2019.228064. doi: 10.3324/haematol.2019.228064. Online ahead of print.

 

Ackermann M, Stark H, Neubert L, Schubert S, Borchert P, Linz F, Wagner WL, Stiller W, Wielpütz M, Hoefer A, Haverich A, Mentzer SJ, Shah HR, Welte T, Kuehnel M, Jonigk D

Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases.

Eur Respir J. 2020 Mar 12;55(3):1900933. 

 

Ackermann M, Verleden SE, Kuehnel M, Haverich A, Welte T, Laenger F, Vanstapel A, Werlein C, Stark H, Tzankov A, Li WW, Li VW, Mentzer SJ, Jonigk D

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.

N Engl J Med. 2020 May 21. doi: 10.1056/NEJMoa2015432. Online ahead of print.

 

Adam BA, Kikic Z, Wagner S, Bouatou Y, Gueguen J, Drieux F, Reid G, Du K, Bräsen JH, D'Agati VD, Drachenberg CB, Farkash EA, Farris AB, Geldenhuys L, Loupy A, Nickeleit V, Rabant M, Randhawa P, Regele H, Mengel M.

Intragraft Gene Expression in Native Kidney BK Virus Nephropathy versus T‐Cell Mediated Rejection: Prospects for Molecular Diagnosis and Risk Prediction.

Am J Transplant. 2020 May 5. doi: 10.1111/ajt.15980. Online ahead of print.

 

Al Krinawe Y, Esmaeilzadeh M, Hartmann C, Krauss JK, Hermann EJ. 

Pediatric rosette-forming glioneuronal tumor of the septum pellucidum.

Childs Nerv Syst. 2020 Mar 26. doi: 10.1007/s00381-020-04575-w. Online ahead of print.

 

Bartels S, Hasemeier B, Vogtmann J, Schipper E, Büsche G, Schlue J, Kreipe H, Lehmann U.

Feasibility of Combined Detection of Gene Mutations and Fusion Transcripts in Bone Marrow Trephines from Leukemic Neoplasms.

J Mol Diagn. 2020 Apr;22(4):591-598. 

 

Bartels S, Faisal M, Büsche G, Schlue J, Hasemeier B, Schipper E, Vogtmann J, Westphal L, Lehmann U, Kreipe H.

Mutations associated with age-related clonal hematopoiesis in PMF patients with rapid progression to myelofibrosis.

Leukemia. 2020 May;34(5):1364-1372.

 

Behling F, Barrantes-Freer A, Behnes C L, Stockhammer F, Rohde V,  Adel-Horowski A, Rodríguez-Villagra OA, Barboza MA, Brück W, Lehmann U, Stadelmann C, Hartmann C

Expression of Olig2, Nestin, NogoA and AQP4 have no impact on overall survival in IDH-wildtype glioblastoma.

PLoS One. 2020 Mar 11;15(3):e0229274.

 

Behr J, Günther A, Bonella F, Dinkel J, Fink L, Geiser T, Geißler K, Gläser S, Handzhhiev S, Jonigk D, Koschel D, Kreuter M, Leuschner G, Markart P, Prasse A, Schönfeld N, Schupp JC, Sitter H, Müller-Quernheim J, Costabel U. 

[German Guideline for Idiopathic Pulmonary Fibrosis].

Pneumologie. 2020 May;74(5):263-293.

 

Bogaard HJ , Legchenko E , Ackermann M , Kühnel MP, Jonigk DD, Chaudhary KR, Sun X, Stewart DJ, Hansmann G. 

The Adult Sprague-Dawley Sugen-Hypoxia Rat Is Still "the One:" A Model of Group 1 Pulmonary Hypertension: Reply to Le Cras and Abman.

Am J Respir Crit Care Med. 2020 Mar 1;201(5):621-624.

 

Delgado SJ, Dehmel S, Twisterling E, Wichmann J, Jonigk D, Warnecke G, Braubach P, Fieguth HG, Wilkens L, Dahlmann F, Kaup FJ, Eggel A, Knauf S, Sewald K, Braun A.

Disruptive anti-IgE Inhibitors Prevent Mast Cell–Dependent Early Airway Response in Viable Atopic Lung Tissue.

J Allergy Clin Immunol. 2020 Feb;145(2):719-722.e1.

 

Derlin T, Werner RA, Lafos M, Henkenberens C, von Klot C AJ, Sommerlath Sohns J, Ross TL, Bengel FM. 

Neuroendocrine Differentiation and Response to PSMA-Targeted Radioligand Therapy in Advanced Metastatic Castration-Resistant Prostate Cancer: a Single-Center Retrospective Study.

J Nucl Med. 2020 Mar 13;doi: 10.2967/jnumed.120.241588. Online ahead of print.

 

Dywicki J, Buitrago-Molina LE, Pietrek J, Lieber M, Broering R, Khera T, Schlue J, Manns MP, Wedemeyer H, Jaeckel E, Hardtke-Wolenski M. 

Autoimmune hepatitis induction can occur in the liver.

Liver Int. 2020 Feb;40(2):377-381. 

 

Ernst P, Engmann B, Frietsch JJ, Schnetzke U, Scholl S, Theis B, Kreipe HH, Ernst T, Glaser A, Haferlach T, Koch T, Hochhaus A, Hilgendorf I.

A 19-year-old patient with atypical chronic myeloid leukemia.

Ann Hematol. 2020 May;99(5):1145-1148.

 

Feist H, Hussein K, Blöcker T, Wohlschlaeger J. 

Pathoanatomical Lesions in Placentas With Excessively Hypercoiled Umbilical Cords: Frequent Detection of Massive Perivillous Fibrin Deposition.

Pediatr Dev Pathol. Mar-Apr 2020;23(2):107-114.

 

Feist H, Hussein K, Stucki-Koch A, Wohlschlaeger J, Hager T, Blöcker T, Heim A. 

Villitis of unknown etiology and chronic deciduitis are not associated with human papilloma virus and enterovirus infection.

Virchows Arch. 2020 Feb 5. doi: 10.1007/s00428-020-02765-0. Online ahead of print.

 

Gambichler T, Doerler M, Nöpel-Dünnebacke S, Matschke J, Bräsen JH, Linke RP, Susok L. 

Haemorrhagic bullous lesions in cutaneous light-chain amyloidosis with smouldering myeloma.

J Eur Acad Dermatol Venereol. 2020 Jan;34(1):e13-e15. 

 

Gluz O, Kolberg-Liedtke C, Prat A, Christgen M, Gebauer D, Kates R, Paré L, Grischke EM, Forstbauer H, Braun M, Warm M, Hackmann J, Uleer C, Aktas B, Schumacher C, Kuemmel S, Wuerstlein R, Pelz E, Nitz U, Kreipe HH, Harbeck N.

Efficacy of deescalated chemotherapy according to PAM50 subtypes, immune and proliferation genes in triple-negative early breast cancer: Primary translational analysis of the WSG-ADAPT-TN trial.

Int J Cancer. 2020 Jan 1;146(1):262-271.

 

Greer M, Werlein C, Jonigk D

Surveillance for acute cellular rejection after lung transplantation.

Ann Transl Med. 2020 Mar;8(6):410.

 

Greunz EM, Lemberger K, Catinaud J, Chenet B, Linke RP, Bräsen JH, Schmitz J, Bertelsen MF. 

Amyloidosis in Caracals (Caracal Caracal).

J Zoo Wildl Med. 2020 Mar 17;51(1):202-209.

 

Haake K, Neehus A-L , Buchegger T, Kühnel MP, Blank P, Philipp F, Oleaga-Quintas C, Schulz A, Grimley M, Goethe R, Jonigk D, Kalinke U, Boisson-Dupuis S, Casanova J-L , Bustamante J, Lachmann N. 

Patient iPSC-Derived Macrophages to Study Inborn Errors of the IFN-γ Responsive Pathway.

Cells. 2020 Feb 19;9(2):483. 

 

Höfer A, Jonigk D, Hartleben B, Verboom M, Hallensleben M, Hübscher SG, Manns MP, Jaeckel E, Taubert R.

DSA are associated with more graft injury, more fibrosis, and upregulation of rejection-associated transcripts in subclinical rejection.

Transplantation. 2020 Mar;104(3):551-561.

 

Kim EL , Sorokin M, Kantelhardt SR, Kalasauskas D, Sprang B, Fauss J, Ringel F, Garazha A, Albert E, Gaifullin N, Hartmann C, Naumann N, Bikar SE, Giese A, Buzdin A. 

Intratumoral heterogeneity and longitudinal changes in gene expression predict differential drug sensitivity in newly diagnosed and recurrent glioblastoma.

Cancers (Basel). 2020 Feb 24;12(2):520. 

 

Kirchner M, Glade J, Lehmann U, Merkelbach-Bruse S, Hummel M, Lehmann A, Trautmann M, Kumbrink J, Jung A, Dietmaier W, Endris V, Kazdal D, Ploeger C, Evert M, Horst D, Kreipe H, Kirchner T, Wardelmann E, Büttner R, Weichert W, Dietel M, Schirmacher P, Stenzinger A, Pfarr N. 

NTRK testing: First results of the QuiP-EQA scheme and a comprehensive map of NTRK fusion variants and their diagnostic coverage by targeted RNA-based NGS assays.

Genes Chromosomes Cancer. 2020 Apr 22. doi: 10.1002/gcc.22853. Online ahead of print.

 

Mayer U, Schmitz J, Bräsen JH, Pape L. 

Crescentic glomerulonephritis in children.

Pediatr Nephrol. 2020 May;35(5):829-842.

 

Melchert J, Henningfeld KA, Richts S, Lingner T, Jonigk D, Pieler T. 

The secreted BMP antagonist ERFE is required for the development of a functional circulatory system in Xenopus.

Dev Biol. 2020 Mar 15;459(2):138-148.

 

Mishra A, Emamgholi F, Erlangga Z, Hartleben B, Unger K, Wolff K, Teichmann U, Kessel M, Woller N, Kühnel F, Dow LE, Manns MP, Vogel A, Lowe SW, Saborowski A, Saborowski M. 

Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing.

Carcinogenesis. 2020 May 14;41(3):334-344.

 

Mynarek M, von Hoff K, Pietsch T, Ottensmeier H, Warmuth-Metz M, Bison B, Pfister S, Korshunov A, Sharma T, Jaeger N, Ryzhova M, Zheludkova O, Golanov A, Rushing EJ, Hasselblatt M, Koch A, Schüller U, von Deimling A, Sahm F, Sill M, Riemenschneider MJ, Dohmen H, Monoranu CM, Sommer C, Staszewski O, Mawrin C, Schittenhelm J, Brück W, Filipski K, Hartmann C, Meinhardt M, Pietschmann K, Haberler C, Slavc I, Gerber NU, Grotzer M, Benesch M, Schlegel PG, Deinlein F, von Bueren AO, Friedrich C, Juhnke BO, Obrecht D, Fleischhack G, Kwiecien R, Faldum A, Kortmann RD, Kool M, Rutkowski S. 

Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort.

J Clin Oncol. 2020 Apr 24;JCO1903057. doi: 10.1200/JCO.19.03057. Online ahead of print.

 

Neubert L, Borchert P, Stark H, Hoefer A, Vogel-Claussen J, Warnecke G, Eubel H, Kuenzler P, Kreipe HH, Hoeper MM, Kuehnel M, Jonigk D

Molecular Profiling of Vascular Remodeling in Chronic Pulmonary Disease.

Am J Pathol. 2020 Apr 7;S0002-9440(20)30145-0. doi: 10.1016/j.ajpath.2020.03.008. Online ahead of print.

 

Niehues T, Özgür TT, Bickes M, Waldmann R, Schöning J, Bräsen J, Hagel C, Ballmaier M, Klusmann JH, Niedermayer A, Pannicke U, Enders A, Dückers G, Siepermann K, Hempel J, Schwarz K, Viemann D.

Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pre-excitation syndrome.

Eur J Immunol. 2020 Mar 17. doi: 10.1002/eji.201948504. Online ahead of print.

 

Pfarr N, Kirchner M, Lehmann U, Leichsenring J, Merkelbach-Bruse S, Glade J, Hummel M, Stögbauer F, Lehmann A, Trautmann M, Kumbrink J, Jung A, Dietmaier W, Endris V, Kazdal D, Evert M, Horst D, Kreipe H, Kirchner T, Wardelmann E, Lassen U, Büttner R, Weichert W, Dietel M, Schirmacher P, Stenzinger A. 

Testing NTRK testing: Wet-lab and in silico comparison of RNA-based targeted sequencing assays.

Genes Chromosomes Cancer. 2020 Mar;59(3):178-188.

 

Schaadt NS, Schönmeyer R, Forestier G, Brieu N, Braubach P, Nekolla K, Meyer-Hermann M, Feuerhake F

Graph-based description of tertiary lymphoid organs at single-cell level.

PLoS Comput Biol. 2020 Feb 21;16(2):e1007385.

 

Schirmer B, Rother T, Bruesch I, Bleich A, Werlein C, Jonigk D, Seifert R, Neumann D. 

Genetic deficiency of the histamine H4-receptor reduces experimental colorectal carcinogenesis in mice.

Cancers (Basel). 2020 Apr 8;12(4):912.

 

Sen P, Helmke A, Liao CM, Sörensen-Zender I, Rong S, Bräsen JH, Melk A, Haller H, von Vietinghoff S, Schmitt R. 

SerpinB2 Regulates Immune Response in Kidney Injury and Aging.

J Am Soc Nephrol. 2020 May;31(5):983-995. 

 

Serth J, Peters I, Dubrowinskaja N, Reese C, Albrecht K, Klintschar M, Lafos M, Grote A, Becker A, Hennenlotter J, Stenzl A, Tezval H, Kuczyk MA. 

Age-, tumor-, and metastatic tissue-associated DNA hypermethylation of a T-box brain 1 locus in human kidney tissue.

Clin Epigenetics. 2020 Feb 18;12(1):33

 

Sieweke J-T, Akin M, Stetskamp S, Riehle C, Jonigk D, Flierl U, Pfeffer TJ, Hirsch V, Dutzmann J, Hoeper MM, Kühn C, Bauersachs J, Schäfer A. 

Mechanical Circulatory Support in Refractory Cardiogenic Shock due to Influenza Virus-Related Myocarditis.

Eur Respir J. 2020 May 12;2000925. doi: 10.1183/13993003.00925-2020. Online ahead of print.

 

Soudah B.

Metastasen in der Leber.

CYTO-INFO. 2020; 3: 79-85

 

Soudah B, Oberndörfer AK.

Zytologie der Speicheldrüsen mit Differentialdignosen.

CYTO-INFO. 2020; 1: 125-131

 

Van Alem CMA, Schmidbauer M, Rong S, Derlin K, Schmitz J, Bräsen JH, Thorenz A, Chen R, Ruben JM, Winter EM, Schilperoort M, Kooijman S, Lalai RA, Metselaar JM, Klemann C, Meier M, van Kooten C, Gueler F, Rotmans JI. 

Liposomal delivery improves the efficacy of prednisolone to attenuate renal inflammation in a mouse model of acute renal allograft rejection.

Transplantation. 2020 Apr;104(4):744-753.

 

Verleden SE, Vanstapel A, De Sadeleer L, Weynand B, Boone M, Verbeken E, Piloni D, Van Raemdonck D, Ackermann M, Jonigk DD, Verschakelen J, Wuyts WA. 

Quantitative analysis of airway obstruction in lymphangio-leio-myomatosis.

Eur Respir J. 2020 Feb 27;1901965. doi: 10.1183/13993003.01965-2019. Online ahead of print.

 

Verleden SE, Von der Thüsen J, Roux A, Brouwers ES, Braubach P, Kuehnel M, Laenger F, Jonigk D

When tissue is the issue: A histological review of chronic lung allograft dysfunction.

Am J Transplant. 2020 Mar 17. doi: 10.1111/ajt.15864. Online ahead of print.

 

Volkmann J, Schmitz J, Nordlohne J, Dong L, Helmke A, Sen P, Immenschuh S, Bernhardt WM, Gwinner W, Bräsen JH, Schmitt R, Haller H, von Vietinghoff S. 

Kidney injury enhances renal G-CSF expression and modulates granulopoiesis and human neutrophil CD177 in vivo..

Clin Exp Immunol. 2020 Jan;199(1):97-108.

 

Werlein C, Seidel A, Warnecke G, Gottlieb J, Laenger F, Jonigk D

Lung Transplant Pathology: An Overview on Current Entities and Procedures.

Surg Pathol Clin. 2020 Mar;13(1):119-140.

 

Yuzefovych Y, Valdivia E, Rong S, Hack F, Rother T, Schmitz J, Bräsen JH, Wedekind D, Moers C, Wenzel N, Gueler F, Blasczyk R, Figueiredo C.

Genetic Engineering of the Kidney to Permanently Silence MHC Transcripts During ex vivo Organ Perfusion.

Front Immunol. 2020 Feb 19;11:265. 

 

 

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