hepatocytes by technologies such as gene therapy. Unfortunately, the promising results obtained in animal models could not be successfully transferred into clinical application in man, yet. The aim of our
biochemical, cell- and molecular biology techniques in model cell lines (rat, mouse, human) as well as animal models of diabetes. Our aims are: Mechanisms of beta cell dysfunction and death in T1DM and T2DM
PhD students are fully financed for 3-4 years. Courses available outside the curriculum include: Animal Handling Gene Technology Omics and Bioinformatics Good Scientific Practise Master Class Lectures
25). In Germany and Europe, HEV has its natural reservoir in pigs. The infection can spread from animals to humans, which is called a zoonosis. This often happens through incompletely heated or raw meat [...] hand disinfection in everyday clinical practice when dealing with hepatitis E patients and infected animals. Together with the team of Eike Steinmann, formerly head of the research group "Virus Transmission"
transporter – in experimental colitis Supervisor: Prof. André Bleich, PhD, Institute for Laboratory Animal Science, MHH Academic Background: Biotechnology Medical Specialty, University of Pécs, Medical School [...] soluble CD14 in mouse colitis models Supervisor: Prof. André Bleich, PhD, Institute for Laboratory Animal Science, MHH Academic Background: Veterinary Medicine, TiHo Mareike Schubert Research Topic: Mechanisms
profiling strategies, indicative tox and PK studies, safety and efficacy studies in small and large animals. IMTTS also works closely together with the Hannover Clinical Research Center (CRC; https://www.
gain insights in the human neocortex, which finally aims at refining, reducing and replacing (3R) animal experiments. In conclusion, this research focus will elucidate the neuroanatomical basis for functional [...] always meeting patients expectations. In many years of research in peripheral nerve regeneration using animal models and in vitro systems, we contributed to the clinical approval of chitosan-based nerve guides [...] system. In this project we collaborate with the Gnotobiotic Group at the MHH-Institute for Laboratory Animal Science (Dr. Marijana Basic, Dr. Silvia Bolsega) and colleagues from Italy (Prof. Giulia Ronchi,
gain insights in the human neocortex, which finally aims at refining, reducing and replacing (3R) animal experiments. In conclusion, this research focus will elucidate the neuroanatomical basis for functional [...] always meeting patients expectations. In many years of research in peripheral nerve regeneration using animal models and in vitro systems, we contributed to the clinical approval of chitosan-based nerve guides [...] system. In this project we collaborate with the Gnotobiotic Group at the MHH-Institute for Laboratory Animal Science (Dr. Marijana Basic, Dr. Silvia Bolsega) and colleagues from Italy (Prof. Giulia Ronchi,
Todorović Z*, Kahrass H, Selter F (2024): Interdisciplinary animal research ethics – challenges, opportunities, and perspectives. Animals 14(19):2896 (* gleichwertiger Beitrag). doi: 10.3390/ani14192896 [...] (2024): Why Do I Choose an Animal Model or an Alternative Method in Basic and Preclinical Biomedical Research? A Spectrum of Ethically Relevant Reasons and Their Evaluation. Animals 14, 651. doi: 10.3390/
ik an der Evangelischen Akademie Loccum * * * 5.-9.9.2022 Animal Research Ethics as Interaction of Research Ethics, Animal Ethics and (Animal Protection) Law International Perspectives on Theoretical and