Frahm M, Heise U, Zimmermann K, Erhardt M, Weiss S. Oncotarget. 2017 Jul 25;8(30):49988-50001. Therapeutic benefit of Salmonella attributed to LPS and TNF-α is exhaustible and dictated by tumor susceptibility [...] Falk CS, Seidler U, Hornef MW, Goethe R, Weiss S. Front Cell Infect Microbiol. 2017 Mar 16;7:75. Therapeutic Potential of Bacteria against Solid Tumors. Hatzikirou H, López Alfonso JC, Leschner S, Weiss S

and research. To gain a deeper understanding of complex diseases and establish novel innovative therapeutic interventions, joint strengths are required. Our research groups do thus collaborate with ample [...] aims to find out which intervention is most suitable for which patient and which factors cause therapeutic success. E.g., as part of moderator analyzes, this study aims to answer whether early traumatic [...] A follow-up survey after 48 weeks will provide valuable data regarding the sustainability of therapeutic improvements. Finally, the health economic potential of the interventions is examined with the

mortality. Based on this finding we have conducted a series of experiments exploring potential therapeutic strategies (antibody, siRNA etc.) to eliminate or block the injurious Angpt-2 protein in sepsis [...] 2012;40(11):3034-41. Clinical: Stahl K, Busch M, Fuge J, Schneider A, Manns MP, Seeliger B, et al. Therapeutic plasma exchange in acute on chronic liver failure. Journal of clinical apheresis. 2020. Stahl K [...] 2020;57:124-9. Stahl K, Schmidt JJ, Seeliger B, Schmidt BMW, Welte T, Haller H, et al. Effect of therapeutic plasma exchange on endothelial activation and coagulation-related parameters in septic shock. Critical

aggregation leading to neurodegeneration and present current research on the development of novel therapeutic strategies in the treatment of neurodegenerative diseases. For further details please contact:

der Studie „Aortic Valve Replacement using Individualised Regenerative Allografts: Bridging the Therapeutic Gap" (ARISE), die von der Europäischen Union (EU) seit 2015 mit fünf Millionen Euro für vier Jahre

Neuroepigenetics and RNA-based therapies) Animalfree model systems for the investigation of novel therapeutic approaches (AG Neuroepigenetics and RNA-based therapies; AG Advanced Tissue Culture Models) Biomimetic

Vanessa Hamann aus der AG Ott "Development and evaluation of RNA-mediated base editing for the therapeutic correction of the C282Y variant causing hereditary hemochromatosis" Maja Strunk aus der aus der

functions and the development of new therapeutic strategies for cardiovascular diseases is a major focus of Professor Thum's Institute of Molecular and Translational Therapeutic Strategies (IMTTS) at Hannover [...] Thum entitled: “ CircRNAs as new therapeutic targets in HFpEF”, “MicroRNAs targeting the SARS-CoV-2 entry receptor ACE2 in cardiomyocytes”, and “ncRNAs-based therapeutic approaches in HF”. IMTTS researchers: [...] about the function and potential therapeutic modulation using in vitro and ex vivo models of HFpEF, (2) to establish a new cell‑type specific circRNA-based therapeutic approach of HFpEF and (3) to test

which has been successfully applied in our projects. This method can help extend the range of new therapeutic targets, speed up the development of antimicrobials and immunomodulatory agents, and enhance the

transplant engineering. His work centers around the alloimmune response in organ transplantation and therapeutic interventions to combat rejection and infection. This includes cellular and humoral immunotherapy [...] structure, molecular function and regulation of histocompatibility systems in order to identify therapeutic targets for graft engineering to substantially improve clinical outcome of transplantation. Professor