induced reboot of human somatic cells. Lange L, Esteban MA, Schambach A. Signal Transduct Target Ther 2022;7(1):244 DOI: 10.1038/s41392-022-01109-5 Cell transcriptomic atlas of the non-human primate Macaca [...] Nature 2022;604(7907):723-731 DOI: 10.1038/s41586-022-04587-3 Evaluation of lentiviral vectors for the human cell and gene therapy of IFN-γR1-deficient mendelian susceptibility to mycobacterial disease. [...] Res. 2018 Sep 6;46(15):7662-7674. doi: 10.1093/nar/gky536. Human Teratoma-Derived Hematopoiesis Is a Highly Polyclonal Process Supported by Human Umbilical Vein Endothelial Cells. Philipp F, Selich A, Rothe
of a functional promoter of the human plakoglobin gene. Eur J Endocrinol 2001; 145(5): 625-33 Roth-Eichhorn S, Heitmann B, Flemming P, Kubicka S, Trautwein C: Evidence for the decreased expression of the [...] Kispert A, von Wasielewski R, Brabant G: Identification of a Wnt/beta catenin signaling pathway in human thyroid cells. Endocrinology 2001; 142(12): 5261-6 Hogemann D, Flemming P, Kreipe H, Galanski M: [...] Flemming P, Yamamoto M, Shimahara Y, Yamaoka Y, Fukumoto M: Microsatellite instability and alternative genetic pathway in intrahepatic cholangiocarcinoma. J Hepathol 2001; 35(2): 235-44 Nave H, Mössinger E, Feist
of the year 2003 Khaled Alkarsah SYRIA supervisor: Prof. Dr. Schulz, Virology, project: Viral and genetic determinants of KSHV/HHV8 transmission from mothers to children Final exam November 2006 Tammy Bohn [...] PD Dr. Eder, Hematology, OE 6860, project: The use of RNA interference in hematopoetic stem cells for functional genomics Final exam November 2006 Dorothea Prinz (nee Dijkstra) THE NETHERLANDS supervisor: [...] project: Interaction between anaphylatoxins C3a/C5a and T-lymphocytes/ dendritic cells with relevance for inflammatory skin diseases Final exam June 2007 Dorothea Gadzicki (Dr. med.) GERMANY supervisor: Prof
insertion force measurements for cochlear implant surgery. IEEE Trans Biomed Eng 2022; 70(5):1643-1650. Boyle EC, Wunschel EJ, Grassl GA. Salmonella enterica infection of human and mouse colon organoid-derived [...] Franke A, Turner LM, Baines JF. Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in [...] 3. Götting J, Baier C, Panagiota V, Maecker-Kolhoff B, Dhingra A, Heim A. High genetic stability of co-circulating human adenovirus type 31 lineages over 59 years. Virus Evol 2022; 8(2):veac067. Hankel
HSV-1 epitopes for induction of effective CTL-immunity Final exam November 2007 Gamze Erdmann (nee Kabalak) GERMANY supervisor: PD Dr. Witte, Clinical Immunology, OE 6830, project: Genetic risk factors of [...] project: Roads to presentation: Targetting the pathways in antigen uptake to dissect out mechanisms for cross presentation Final exam November 2007 Sangeeta Chauhan INDIA supervisor: Dr. Malek, Gastroen [...] mitotic cyclins like cyclin B or cyclin A by proteolytic mechanisms and role in the development of human malignancies Final exam November 2008 Mingmin Chen CHINA supervisor: Prof. Dr. Seidler, Gastroent
Together with Philipp Altrock and Arne Traulsen from the Max Planck Institute for Evolutionary Biology, we have developed a unique model for lobular carcinoma in situ (LCIS) of the mammary gland. The model [...] carcinoma (ILC). This mechanism provides an explanation for retained E-Cadherin expression in a subset of LCIS and ILC cases and is of tremendous importance for diagnostic pathology. This report was published [...] immunohistochemical markers for the differential diagnosis between collagenous spherulosis and adenoid-cystic carcinoma of the mammary gland. Her study has been published in Human Pathology . https://www.
and its consequences for the MHC-I immunopeptidome Supervisor : Prof. Dr. Lars Dölken, Institute of Virology, MHH Academic Background : Surgery, Beijing Neurosurgical Institute of Capital Medical University [...] Pierina Cetraro Research Topic : Regulation of tRNA biogenesis by Human Cytomegalovirus infections Supervisor: Prof. Dr. Dan Depledge, Institute of Virology, MHH Academic Background : Immunology, Universidad [...] microbiota on infection susceptibility in liver cirrhosis patients Supervisor: PD Dr. Marius Vital, Institute for Medical Microbiology and Hospital Epidemiology, MHH Academic Background: Biomedicine, MHH Konstantinos
discourses in human and veterinary medicine about the end of life care for humans and pets and some consequences for the relations between medical and animal ethics Weiterführende Links Institut für Tierhygiene [...] Sterben wie ein Hund? Konvergenzen und Divergenzen im human- und veterinärmedizinethischen Diskurs zum Lebensende von Menschen bzw. Heimtieren und Folgen für die Verhältnisbestimmung von Medizin- und Tierethik
a scalable bioreactor platform to generate human iPSC-derived hematopoietic cell types for regenerative applications’ Ana-Maria Zamfirescu aus dem Institut für Zellbiochemie ‘The stem cell niche as a [...] in vitro model of Parkinson´s disease' Abhishek Chiyyeadu aus dem Institut für Experimentelle Hämatologie ‘Antibody-based strategies for infections, cancer and regenerative medicine’ Nils Kriedemann aus [...] Infektiologie und Endokrinologie ‘Generation of multicellular human liver microtissue models using organoid-derived and direct reprogrammed human hepatocyte-like cells’ Fawaz Ahmad Saleh aus der Klinik für
from the Institute for Laboratory Animals with histopathologic skills from organ experts in human pathology. In order to enable optimal patho-anatomical interpretation of animal models for human disease [...] associated with novel and experimental therapies and thus acquire the necessary knowledge for interpreting human tissue specimens derived from patients treated by experimental therapy modalities. Consequently [...] disease and regeneration xPa provides a platform for information (modes of fixation and tissue banking), technical support (tissue sections and stain, immunhistochemistry, laser microdissection, RNA analysis)