Reports. 2021. Publisher's page Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning Schwarzer, Adrian, Talbot, Steven R., Selich, Anton, Morgan [...] page Identification and functional characterization of a spliced rhesus rhadinovirus gene with homology to the K15 gene of Kaposi's sarcoma-associated herpesvirus. Wang L, Pietrek M, Brinkmann MM, Havemeier [...] Frontiers in Cellular and Infection Microbiology. 2022. Publisher's page Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication Froese

expression and contractile function are altered by replating stem cell–derived cardiomyocytes, (2023), J Gen Physiol (2023) 155 (11): e202313377, https://doi.org/10.1085/jgp.202313377 , Online ahead of print [...] protein kinases mediate recruitment of CREB-binding protein to preserve fast myosin heavy chain IId/x gene activity in myotubes. J. Biol. Chem., 282, 7265-7275. da Costa, N., Edgar, J., Ooi, P.-T., Su, Y. [...] Meissner, J.D. , and Chang, K.-C., 2007. Calcineurin differentially regulates fast myosin heavy chain genes in oxidative muscle fibre type conversion. Cell Tissue Res., 329, 515-27. Hanke, N., Meissner, J.D

Rahav G, Grassl GA, Gal-Mor O. The emerging Salmonella infantis expresses lower levels of SPI-1 genes and causes milder colitis in mice and lower rates of invasive disease in humans than Salmonella T [...] The core genome m5C methyltransferase JHP1050 (M.Hpy99III) plays an important role in orchestrating gene expression in Helicobacter pylori . Nucleic Acids Res 2019; 47(5):2336-2348. Farowski F, Solbach P [...] 309(6):151336. Selvakumar, Tharini Ashtalakshmi (Dr. rer. nat.). Interferon mediated intestinal epithelial gene expression under homeostatic and inducible conditions. - 201 Blätter: Illustrationen, Diagramme. Suwandi

CRISPR/Cas9-vermittelte Genom-Editing-Tools zur Überprüfung von Chromatin-Ereignissen eines einzelnen Gens, Epigenomik (ChIPseq, Chromosomenkonformationserfassung usw.), Zellschrittmacherexperimente, Messung [...] induces cachexia by impeding transcriptional signaling of the SET1/MLL complex on muscle-specific genes . iScience 27: 110913 Wang T, Nayak A , Kraft T, Amrute-Nayak M (2024) Single-Molecule Investigation [...] S (2017) Flightless-I governs cell fate by recruiting the SUMO isopeptidase SENP3 to distinct HOX genes. Epigenetics Chromatin 10: 15 Jung J, Nayak A , Schaeffer V, Starzetz T, Kirsch AK, Muller S, Dikic

J, Klein C, Schambach A „Lentiviral Gene Therapy and Vitamin B3 Treatment Enable Granulocytic Differentiation of G6PC3-deficient Induced Pluripotent Stem Cells“ Gene Ther 2020 Feb 12 [Online ahead of print] [...] Moritz T, Trapnell BC, Lachmann N. “Function and Safety of Lentivirus-Mediated Gene Transfer for CSF2RA-Deficiency” Hum Gene Ther Methods . 2017 Dec;28(6):318-329 Ackermann M, Kuhn A, Kunkiel J, Merkert [...] Moritz T. „Chemoprotection of murine hematopoietic cells by combined gene transfer of cytidine deaminase (CDD) and multidrug resistance 1 gene (MDR1).“ J Exp Clin Cancer Res . 2015 Dec 12;34:148 Dreyer AK, Hoffmann

killer (NK) cells. A few E3 genes are unique to a particular species and hence may allow for species-specific immunomodulation and differential disease outcome. One of these genes, designated E3/49K, is only [...] infections. E3 is one of the most divergent regions of the Ad genome, differing considerably in size, gene composition and sequence between and within an Ad species. Species D Ads have the largest E3 region

Wageningen University & Research, The Netherlands Xiangming Han Research Topic : Cell type-specific HCMV gene expression and its consequences for the MHC-I immunopeptidome Supervisor : Prof. Dr. Lars Dölken, [...] Research Topic : Development of a screening platform for fine mapping of functional herpes simplex virus gene elements by MuA transposon mutagenesis Supervisor: Prof. Dr. Lars Dölken, Institute of Virology, MHH [...] Immunology, Philipps University Marburg Yan Zheng Research Topic : Functional analysis of cytomegalovirus gene products and cellular effectors during lytic infection Supervisor: Prof. Dr. Lars Dölken, Institute

e Stammzellen ausgeweitet. Burst-like Transkription von HCM-Genen Unsere Arbeitsgruppe konnte zeigen, dass die Allele HCM-assoziierter Gene sowohl in HCM-Patienten als auch in herzgesunden Donoren „ burst-like [...] Imbalance auf Gewebeebene Bei einer rein stochastischen ( burst-like ) Expression beider Allele eines Gens wäre im Mittel ein 50:50 Verhältnis der mRNA beider Allele zu erwarten. Wir konnten jedoch für mehrere [...] vergleichbar. So exprimierten z.B. alle von uns untersuchten Patienten mit der Mutation R723G im MYH7 -Gen im Mittel 68% R723G und 32% Wildtyp-mRNA. Daher müssen neben der Transkription in bursts Mechanismen

Molekularbiologie Teil 1 (Download, pdf) Skript Molekularbiologie Teil 2 ( Download , pdf) GenTG ( Download , pdf) GenDG ( Download , pdf) 6. Semester Fragenkatalog Examen (schriftl.) 2010 ( Download , pdf)

microRNAs in the inhibition of fibrosis is due to the fact that a single miRNA can regulate multiple genes and pathways involved in the development of fibrosis, and therefore using only two microRNAs for therapy [...] therapy of liver fibrosis is advantageous instead of sequentially or simultaneously modulating several genes”. Prof. Sharma states, “we are very excited about the anti-fibrotic potential of miR-190b-5p and