CEO Professor Thum. The lead compound, CDR123L, is a synthetic antisense oligonucleotide and a selective inhibitor of microRNA‑132‑3p (miR-132). miR-132 expression is associated with pathological cardiac [...] therapies March 2024 In a recent study, IMTTS scientists demonstrated for the first time that inhibition of microRNA (miR) - 21 has a cardioprotective effect in human heart tissue. As a new method, the study [...] to fibrosis. "miR-21 plays a decisive role in this development," says Professor Thum. His team investigated what happens when the harmful function of miR-21 is switched off. They used a so-called antisense
mit dem Fraunhofer Institut für Toxikologie und Experimentelle Medizin (ITEM) und der Leibniz Universität Hannover als gemeinsames Netzwerk BREATH ( B iomedical R esearch in E ndstage A nd Obs T ructive [...] der PROBASE-Studie (Risk-adapted prostate cancer early detection study based on a “baseline” PSA value in young men – a prospective multicenter randomized trial) wird ein modernes Konzept zum generellen [...] de/de/forschung/forschungsprojekte/ansicht/projekt/detail/zifco/ Znpp HI Register Znpp HI Register A1-Studie A1-Studie AGO Paola AGO Paola Autismus Biobank Autismus Biobank Belastung Schafe SB Belastung Schafe