„Pan-genotypic neutralization human monoclonal antibodies with enhances effector functions as therapeutic option for Hepatitis E virus infection” erhalten Sie bei Dr. Patrick Behrendt, behrendt.patric
to uncover the fundamental drivers of disease progression and identify actionable targets for therapeutic intervention. Projects Intracellular signaling mechanisms driving malignant hematopoietic cells [...] genome editing to determine their causal roles in disease progression and their potential as therapeutic targets. Bone marrow niche remodeling and intercellular interactions This project investigates
A, Sharma AD . Identification and functional validation of miR-190b-5p and miR-296-3p as novel therapeutic attenuators of liver fibrosis. Journal of Hepatology 2024 Aug 31:S0168-8278(24)02492-9. doi:10 [...] FWR, Cantz T, Horscroft N, Balakrishnan A, Chevessier F, Ott M and Sharma AD . Novel mRNA-based therapeutic approach of delivering transcription factor HNF4A attenuates liver fibrosis. Journal of Hepatology
livers ameliorated liver fibrosis in pre-clinical models. Dr. Balakrishnan mentions, “The promising therapeutic potential of microRNAs in the inhibition of fibrosis is due to the fact that a single miRNA can
tionen unterstützt. Die Originalarbeit “Targeting low levels of MIF expression as a potential therapeutic strategy for ALS” finden Sie hier . Text: Kirsten Pötzke
and in vivo infection studies with human hepatotropic viruses and preclinical evaluation of new therapeutic concepts within the Thematical Translation Unit Hepatitis as well as to support other Thematical
Non-coding RNAs: key regulators of reprogramming, pluripotency, and cardiac cell specification with therapeutic perspective for heart regeneration. Cardiovasc Res. 118(15):3071-3084. https://doi.org/10.1093
Kleinert H (2022) Cell Commun Signal. 20(1):47. https//doi.org/10.1186/s12964-022-00855-x Paving Therapeutic Avenues for FOXG1 Syndrome: Untangling Genotypes and Phenotypes from a Molecular Perspective. Akol
cardioprotective strategies. Our research addresses these dual challenges by focusing on novel therapeutic targets, including various RNAs and RNA-binding proteins, as well as pioneering heart-targeting
: Prof. Dr. Hansmann, Pediatric Cardiology, OE 6730, project: Stem cell and anti-miR-mediated therapeutic interventions for pulmonary vascular disease and right ventricular failure Final exam June 2017