Publikationen

~ in Überarbeitung ~

  • 2023

Hamacher, Rainer, Xiaofei Liu, Markus K. Schuler, Leopold Hentschel, Patrick Schöffski, Hans-Georg Kopp, Sebastian Bauer, Bernd Kasper, Lars Lindner, Jens-Markus Chemnitz, Martina Crysandt, Alexander Stein, Björn Steffen, Stephan Richter, Gerlinde Egerer, Philipp Ivanyi, Annegret Kunitz, and Viktor Grünwald. 2023. “A Post Hoc Analysis of the EPAZ Trial: The Role of Geriatric Variables in Elderly Soft Tissue Sarcoma Patients on Toxicity and Outcome.” European Journal of Cancer 181:145–54. doi: 10.1016/j.ejca.2022.12.012.

Merten, Roland, Mirko Fischer, Hans Christiansen, Susanne Hellms, Christoph Alexander Joachim von Klot, Nele Henrike Thomas, and Anne Caroline Knöchelmann. 2023. “Using A Further Planning MRI after Neoadjuvant Androgen Deprivation Therapy Significantly Reduces the Radiation Exposure of Organs at Risk in External Beam Radiotherapy of Prostate Cancer.” Journal of Clinical Medicine 12(2):574. doi: 10.3390/jcm12020574

  • 2022

Adam, Knut, Hüsamettin Günay, Bernhard Vaske, Marco Flohr, and Ingmar Staufenbiel. 2022. “The Granulation Tissue Preservation Technique in Regenerative Periodontal Surgery—a Randomized Controlled Clinical Trial.” Clinical and Experimental Dental Research (December 2021):1–11. doi: 10.1002/cre2.532.

Binz, Camilla, Alma Osmanovic, Nele H. Thomas, Benjamin Stolte, Maren Freigang, Isabell Cordts, Ramona Griep, Zeljko Uzelac, Claudia D. Wurster, Christoph Kamm, Hannah A. Siegler, Gary Wieselmann, Andreas Hermann, Paul Lingor, Marcus Deschauer, Albert C. Ludolph, Thomas Meyer, René Günther, Tim Hagenacker, Susanne Petri, and Olivia Schreiber-Katz. 2022. “Validity and Reliability of the German Multidimensional Fatigue Inventory in Spinal Muscular Atrophy.” Annals of Clinical and Translational Neurology 9(3):351–62. doi: 10.1002/acn3.51520.

Dey Hazra, Rony-Orijit, Robert Maximillian Blach, Yvonne Ziert, Alexander Ellwein, Mara Warnhoff, Marek Hanhoff, Helmut Lill, and Gunnar Jensen. 2022. “Are Patient-Reported Outcome Scores a Reasonable Substitute for Clinical Follow-up After Surgically Managed Acromioclavicular Joint Injuries?” Orthopaedic Journal of Sports Medicine 10(5):232596712210940. doi: 10.1177/23259671221094056.

Fortmann, Caroline, Thomas Goeen, Norman Zinne, Soeren Wiesner, Benno M. Ure, Claus Petersen, and Joachim F. Kuebler. 2022. “Nickel Contamination after Minimally-Invasive Repair of Pectus Excavatum Persists after Bar Removal.” PloS One 17(10):e0275567. doi: 10.1371/journal.pone.0275567.

Haas, Martina, Ewgeni Jakubovski, Katja Kunert, Carolin Fremer, Nadine Buddensiek, Sebastian Häckl, Martina Lenz-Ziegenbein, Richard Musil, Veit Roessner, Alexander Münchau, Irene Neuner, Armin Koch, and Kirsten Müller-Vahl. 2022. “ONLINE-TICS: Internet-Delivered Behavioral Treatment for Patients with Chronic Tic Disorders.” Journal of Clinical Medicine 11(1):250. doi: 10.3390/jcm11010250.

Haufe, Sven, Hedwig Theda Boeck, Sebastian Häckl, Johanna Boyen, Momme Kück, Clara Catharina van Rhee, Johann-Matthias Graf von der Schulenburg, Jan Zeidler, Torben Schmidt, Heiko Johannsen, Dennis Holzwart, Armin Koch, and Uwe Tegtbur. 2022. “Impact of Electrically Assisted Bicycles on Physical Activity and Traffic Accident Risk: A Prospective Observational Study.” BMJ Open Sport & Exercise Medicine 8(4):e001275. doi: 10.1136/bmjsem-2021-001275.

Kirchner, Theresa, Sophia Heinrich, Agnes Bonifacius, Bastian Engel, Louisa Ruhl, Isabell Pink, Nele Thomas, Joerg Martens, Marius M. Hoeper, Rainer Blasczyk, Heiner Wedemeyer, Elmar Jaeckel, Yang Li, Christine S. Falk, Britta Eiz-Vesper, and Richard Taubert. 2022. “Reduced Humoral but Stable Cellular SARS-CoV-2-Specific Immunity in Liver Transplant Recipients in the First Year after COVID-19.” PLOS ONE 17(11):e0276929. doi: 10.1371/journal.pone.0276929.

Kratz, Christian P., Dmitrii Smirnov, Robert Autry, Natalie Jäger, Sebastian M. Waszak, Anika Großhennig, Riccardo Berutti, Mareike Wendorff, Pierre Hainaut, Stefan M. Pfister, Holger Prokisch, Tim Ripperger, and David Malkin. 2022. “ Heterozygous BRCA1/2 and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents with Cancer .” JNCI: Journal of the National Cancer Institute. doi: 10.1093/jnci/djac151.

Schulze Lammers, Friederike C., Agnes Bonifacius, Sabine Tischer-Zimmermann, Lilia Goudeva, Jörg Martens, Bernd Lepenies, Maria von Karpowitz, Gunilla Einecke, Gernot Beutel, Thomas Skripuletz, Rainer Blasczyk, Rita Beier, Britta Maecker-Kolhoff, and Britta Eiz-Vesper. 2022. “Antiviral T-Cell Frequencies in a Healthy Population: Reference Values for Evaluating Antiviral Immune Cell Profiles in Immunocompromised Patients.” Journal of Clinical Immunology (0123456789). doi: 10.1007/s10875-021-01205-1.

  • 2021

Ahlenstiel-Grunow, Thurid, Xiaofei Liu, Raphael Schild, Jun Oh, Christina Taylan, Lutz T. Weber, Hagen Staude, Murielle Verboom, Christoph Schröder, Ruxandra Sabau, Anika Großhennig, and Lars Pape. 2021. “Steering Transplant Immunosuppression by Measuring Virus-Speci Fi c T Cell Levels : The Randomized , Controlled IVIST Trial.” J Am Soc Nephrol 32(2):502–16. doi: 10.1681/ASN.2020050645.

Albrecht, Fenja, Heidi Wolters, Yvonne Ziert, Beate Timmermann, Rolf Dieter Kortmann, Christiane Matuschek, Christian Rübe, Carmen Martini, Hans Christiansen, Hans Theodor Eich, Normann Willich, and Diana Steinmann. 2021. “Evaluation of Treatment-Associated Eye Toxicity after Irradiation in Childhood and Adolescence—Results from the Registry of the Evaluation of Side Effects after Radiotherapy in Childhood and Adolescence (RiSK).” Strahlentherapie Und Onkologie 197(8):700–710. doi: 10.1007/s00066-021-01793-2.

Burger, Hans Ulrich, Christoph Gerlinger, Chris Harbron, Armin Koch, Martin Posch, Justine Rochon, and Anja Schiel. 2021. “The Use of External Controls: To What Extent Can It Currently Be Recommended?” Pharmaceutical Statistics (January):pst.2120. doi: 10.1002/pst.2120.

Gornyk, Daniela, Martina Scharlach, Brigitte Buhr-Riehm, Carolina Judith Klett-Tammen, Sveja Eberhard, Jona Theodor Stahmeyer, Anika Großhennig, Andrea Smith, Sarah Meinicke, Wilfried Bautsch, Gérard Krause, and Stefanie Castell. 2021. “Effectiveness of Trainings of General Practitioners on Antibiotic Stewardship: Methods of a Pragmatic Quasi-Experimental Study in a Controlled Before-After Design in South-East-Lower Saxony, Germany (WASA).” Frontiers in Pharmacology 12(April):1–9. doi: 10.3389/fphar.2021.533248.

Lasch, Florian, Lorenzo Guizzaro, Armin Koch, and Lukas Aguirre Dávila. 2021. “Potential Impact of COVID-19 on Ongoing Clinical Trials : A Simulation Study with the Neurological Yale Global Tic Severity Scale Based on the CANNA-TICS Study.” Pharmaceutical Statistics (January):1–17. doi: 10.1002/pst.2100.

Madadi-Sanjani, Omid, Christoph Zoeller, Joachim F. Kuebler, Alejandro D. Hofmann, Jens Dingemann, Soeren Wiesner, Julia Brendel, and Benno M. Ure. 2021. “Severity Grading of Unexpected Events in Paediatric Surgery: Evaluation of Five Classification Systems and the Comprehensive Complication Index (CCI®).” BJS Open 5(6). doi: 10.1093/bjsopen/zrab138.

Schwarz, Anke, Frank Schäfer, Theodor Framke, Silvia Linnenweber-Held, Nicolas Richter, and Hermann Haller. 2021. “Risk Factors Influencing the Outcomes of Kidney Re-Transplantation.” Annals of Transplantation 26:1–23. doi: 10.12659/AOT.928922.

Pellicer, Adelina, Ramón Fernández, Vincent Jullien, Clare Gleeson, María Carmen Bravo, Paloma López Ortego, Laura Sánchez, Marta Ybarra, Héctor Rojas-Anaya, Fernando Cabañas, Armin Koch, Andrea Smith, and Heike Rabe. 2021. “Pharmacokinetic Study (Phase I−II) of a New Dobutamine Formulation in Preterm Infants Immediately after Birth.” Pediatric Research 89(4):981–86. doi: 10.1038/s41390-020-1009-0.

Waschkies, Freya, Luka Kroning, Thilo Schill, Arvind Chandra, Cordula Schippert, Dagmar Töpfer, Yvonne Ziert, and Frauke von Versen-Höynck. 2021. “Pregnancy Outcomes After Frozen-Thawed Embryo Transfer in the Absence of a Corpus Luteum.” Frontiers in Medicine 8(September):1–11. doi: 10.3389/fmed.2021.727753.

  • 2020

Aguirre Dávila, Lukas, Armin Koch, and Florian Lasch. 2020. “Randomization versus Real-World Evidence.” New England Journal of Medicine 383(4):e21. doi: 10.1056/nejmc2020020.

Bunk, Daniel, Michael Eisenburger, Sebastian Häckl, Jörg Eberhard, Meike Stiesch, and Jasmin Grischke. 2020. “The Effect of Adjuvant Oral Irrigation on Self‐administered Oral Care in the Management of Peri‐implant Mucositis: A Randomized Controlled Clinical Trial.” Clinical Oral Implants Research 31(10):946–58. doi: 10.1111/clr.13638.

Clausen, Jan-Dierk, Niclas Nahen, Hauke Horstmann, Florian Lasch, Werner Krutsch, Christian Krettek, and Thomas Sanjay Weber-Spickschen. 2020. “Improving Maximal Strength in the Initial Postoperative Phase After Anterior Cruciate Ligament Reconstruction Surgery: Randomized Controlled Trial of an App-Based Serious Gaming Approach.” JMIR Serious Games 8(1):e14282. DOI:10.2196/14282.

Cornberg, Markus, Sven Pischke, Tobias Müller, Patrick Behrendt, Felix Piecha, Julia Benckert, Daniel Todt, Eike Steinmann, Armin Papkalla, Maria von Karpowitz, Armin Koch, Ansgar Lohse, Svenja Hardtke, Michael P. Manns, and Heiner Wedemeyer. 2020. “Sofosbuvir Monotherapy Fails to Achieve HEV RNA Elimination in Patients with Chronic Hepatitis E – The HepNet SofE Pilot Study.” Journal of Hepatology 73(3):696–99. doi: 10.1016/j.jhep.2020.05.020.

Großhennig, Anika, and Armin Koch. 2020. “COVID-19 Hits a Trial: Arguments against Hastily Deviating from the Plan.” Contemporary Clinical Trials 98:106155.doi: 10.1016/j.cct.2020.106155.

Grünwald, Viktor, Annika Karch, Markus Schuler, Patrick Schöffski, Hans-Georg Kopp, Sebastian Bauer, Bernd Kasper, Lars H. Lindner, Jens-Marcus Chemnitz, Martina Crysandt, Alexander Stein, Björn Steffen, Stephan Richter, Gerlinde Egerer, Philipp Ivanyi, Silke Zimmermann, Xiaofei Liu, and Annegret Kunitz. 2020. “Randomized Comparison of Pazopanib and Doxorubicin as First-Line Treatment in Patients With Metastatic Soft Tissue Sarcoma Age 60 Years or Older: Results of a German Intergroup Study.” Journal of Clinical Oncology 38(30):3555–64. doi: 10.1200/JCO.20.00714.

Heinemann, Nele Carolin, Sabine Tischer-Zimmermann, Torge Christian Wittke, Julian Eigendorf, Arno Kerling, Theodor Framke, Anette Melk, Hans-Gert Heuft, Rainer Blasczyk, Britta Maecker-Kolhoff, and Britta Eiz-Vesper. 2020. “High-Intensity Interval Training in Allogeneic Adoptive T-Cell Immunotherapy – a Big HIT?” Journal of Translational Medicine 18(1):148. https://doi.org/10.1186/s12967-020-02301-3.

Holstein, Katharina, Xiaofei Liu, Andrea Smith, Paul Knöbl, Robert Klamroth, Ulrich Geisen, Hermann Eichler, Wolfgang Miesbach, and Andreas Tiede. 2020. “Bleeding and Response to Hemostatic Therapy in Acquired Hemophilia A (AHA): Results from the GTH-AH 01/2010 Study.” Blood 136(3):279–87. doi: 10.1182/blood.2019003639.

Horstmann, Hauke, Pascal Medico, Florian Lasch, Werner Krutsch, and Thomas Sanjay Weber-Spickschen. 2020. “Simplified Measurement of Maximum Strength After Knee Surgery: Application-Based Knee-Training Device Compared to Isokinetic Testing.” Open Access Journal of Sports Medicine Volume 11:43–49. DOI: 10.2147/OAJSM.S214598.

Jakubovski, Ewgeni, Anna Pisarenko, Carolin Fremer, Martina Haas, Marcus May, Carsten Schumacher, Christoph Schindler, Sebastian Häckl, Lukas Aguirre Davila, Armin Koch, Alexander Brunnauer, Camelia Lucia Cimpianu, Beat Lutz, Laura Bindila, and Kirsten Müller-Vahl. 2020. “The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols in the Treatment of Adults With Chronic Tic Disorders.” Frontiers in Psychiatry 11. doi: 10.3389/fpsyt.2020.575826.

Konrad, Simon, Theodor Framke, Eugen Kludt, Andreas Büchner, Thomas Lenarz, and Gerrit Paasche. 2020. “Do Impedance Changes Correlate With a Delayed Hearing Loss After Hybrid L24 Implantation?” Ear & Hearing Publish Ah. doi: 10.1097/AUD.0000000000000914.

Lasch, Florian, Annika Karch, Armin Koch, Thorsten Derlin, Andreas Voskrebenzev, Tawfik Moher Alsady, Marius M. Hoeper, Henning Gall, Fritz Roller, Sebastian Harth, Dagmar Steiner, Gabriele Krombach, Hossein Ardeschir Ghofrani, Fabian Rengier, Claus Peter Heußel, Ekkehard Grünig, Dietrich Beitzke, Marcus Hacker, Irene M. Lang, Jürgen Behr, Peter Bartenstein, Julien Dinkel, Kai-Helge Schmidt, Karl-Friedrich Kreitner, Thomas Frauenfelder, Silvia Ulrich, Okka W. Hamer, Michael Pfeifer, Christopher S. Johns, David G. Kiely, Andrew James Swift, Jim Wild, and Jens Vogel-Claussen. 2020. “Comparison of MRI and VQ-SPECT as a Screening Test for Patients With Suspected CTEPH: CHANGE-MRI Study Design and Rationale.” Frontiers in Cardiovascular Medicine 7:51. doi: 10.3389/fcvm.2020.00051.

Mederacke, Young-Seon, Martha M. Kirstein, Anika Großhennig, Silke Marhenke, Frauke Metzler, Michael P. Manns, Arndt Vogel, and Ingmar Mederacke. 2020. “The PNPLA3 Rs738409 GG Genotype Is Associated with Poorer Prognosis in 239 Patients with Autoimmune Hepatitis.” Alimentary Pharmacology & Therapeutics 51(11):1160–68. doi: 10.1111/apt.15722.

Plaass, Christian, Annika Karch, Armin Koch, Vivien Wiederhoeft, Sarah Ettinger, Leif Claassen, Kiriakos Daniilidis, Daiwei Yao, and Christina Stukenborg-Colsman. 2020. “Short Term Results of Dynamic Splinting for Hallux Valgus — A Prospective Randomized Study.” Foot and Ankle Surgery 26(2):146–50. doi: 10.1016/j.fas.2019.01.002.

Scheper, Verena, Melanie Schmidtheisler, Florian Lasch, Heiko von der Leyen, Armin Koch, Jana Schwieger, Andreas Büchner, Anke Lesinski-Schiedat, and Thomas Lenarz. 2020. “Randomized Placebo-Controlled Clinical Trial Investigating the Effect of Antioxidants and a Vasodilator on Overall Safety and Residual Hearing Preservation in Cochlear Implant Patients.” Trials 21(1):643. doi: 10.1186/s13063-020-04522-9.

Solbach, Philipp, Patrick Chhatwal, Sabrina Woltemate, Evelina Tacconelli, Michael Buhl, Ingo B. Autenrieth, Maria J. G. T. Vehreschild, Nathalie Jazmati, Markus Gerhard, Christoph K. Stein-Thoeringer, Jan Rupp, Kurt Ulm, Armin Ott, Florian Lasch, Armin Koch, Michael P. Manns, Sebastian Suerbaum, and Oliver Bachmann. 2020. “Microbiota-Associated Risk Factors for C. Difficile Acquisition in Hospitalized Patients: A Prospective, Multicentric Study.” Clinical Infectious Diseases. doi: 10.1093/cid/ciaa871.

Tenhunen, Olli, Florian Lasch, Anja Schiel, and Miia Turpeinen. 2020. “Single‐Arm Clinical Trials as Pivotal Evidence for Cancer Drug Approval: A Retrospective Cohort Study of Centralized European Marketing Authorizations Between 2010 and 2019.” Clinical Pharmacology & Therapeutics 108(3):653–60. doi: 10.1002/cpt.1965.

von Versen-Höynck, Frauke, Sebastian Häckl, Elif Seda Selamet Tierney, Kirk P. Conrad, Valerie L. Baker, and Virginia D. Winn. 2020. “Maternal Vascular Health in Pregnancy and Postpartum After Assisted Reproduction.” Hypertension 75(2):549–60. doi: 10.1161/HYPERTENSIONAHA.119.13779.

Westhoff-Bleck, Mechthild, Lotta Winter, Lukas Aguirre Davila, Christoph Herrmann-Lingen, Jens Treptau, Johann Bauersachs, Stefan Bleich, and Kai G. Kahl. 2020. “Diagnostic Evaluation of the Hospital Depression Scale (HADS) and the Beck Depression Inventory II (BDI-II) in Adults with Congenital Heart Disease Using a Structured Clinical Interview: Impact of Depression Severity.” European Journal of Preventive Cardiology 27(4):381–90. doi: 10.1177/2047487319865055.

  • 2019

Abeling, Tanja, Irina Scheffner, Annika Karch, Verena Broecker, Armin Koch, Hermann Haller, Anke Schwarz, and Wilfried Gwinner. 2019. “Risk Factors for Death in Kidney Transplant Patients: Analysis from a Large Protocol Biopsy Registry.” Nephrology Dialysis Transplantation 34(7):1171–81. doi: 10.1093/ndt/gfy131.

Aguirre Dávila, Lukas, Kristina Weber, Udo Bavendiek, Johann Bauersachs, Janet Wittes, Salim Yusuf, and Armin Koch. 2019. “Digoxin–Mortality: Randomized vs. Observational Comparison in the DIG Trial.” European Heart Journal 40(40):3336–41. doi: 10.1093/eurheartj/ehz395.

Albrecht, Urs-Vito, Theodor Framke, and Ute von Jan. 2019. “Quality Awareness and Its Influence on the Evaluation of App Meta-Information by Physicians: Validation Study.” JMIR MHealth and UHealth 7(11):e16442. doi: 10.2196/16442.

Alter, Peter, Henrik Watz, Kathrin Kahnert, Klaus F. Rabe, Frank Biertz, Ronald Fischer, Philip Jung, Jana Graf, Robert Bals, Claus F. Vogelmeier, and Rudolf A. Jörres. 2019. “Effects of Airway Obstruction and Hyperinflation on Electrocardiographic Axes in COPD.” Respiratory Research 20(1):61. doi: 10.1186/s12931-019-1025-y.

Baier, Claas, Ramin Ipaktchi, Frank Schwab, Andrea Smith, Xiaofei Liu, Ella Ebadi, Anne Limbourg, Tobias R. Mett, Franz-Christoph Bange, and Peter Maria Vogt. 2019. “Universal Decolonization with Octenidine: First Experiences in a Tertiary Burn Intensive Care Unit.” Burns Open 3(1):8–11. doi: 10.1016/j.burnso.2018.10.003.

Bavendiek, Udo, Dominik Berliner, Lukas Aguirre Dávila, Johannes Schwab, Lars Maier, Sebastian A. Philipp, Andreas Rieth, Ralf Westenfeld, Christopher Piorkowski, Kristina Weber, Anja Hänselmann, Maximiliane Oldhafer, Sven Schallhorn, Heiko von der Leyen, Christoph Schröder, Christian Veltmann, Stefan Störk, Michael Böhm, Armin Koch, Johann Bauersachs, Udo Bavendiek, Johann Bauersachs, Armin Koch, Heiko von der Leyen, Christian Veltmann, Michael Böhm, Stefan Störk, Ulrich Tebbe, Stephan von Haehling, Markus Haass, Stefan Anker, Paul Mohacsi, Gerhard Pölzl, Helmut Trampisch, Lukas Aguirre Dávila, Kristina Weber, Silke Zimmermann, and Barbara Neuhaus. 2019. “Rationale and Design of the DIGIT‐HF Trial (DIGitoxin to Improve OuTcomes in Patients with Advanced Chronic Heart Failure): A Randomized, Double‐blind, Placebo‐controlled Study.” European Journal of Heart Failure 21(5):676–84. doi: 10.1002/ejhf.1452.

Bräsen, Jan Hinrich, Young‐Seon Mederacke, Jessica Schmitz, Kateryna Diahovets, Abedalrazag Khalifa, Björn Hartleben, Fermín Person, Thorsten Wiech, Eric Steenbergen, Anika Großhennig, Michael P. Manns, Roland Schmitt, and Ingmar Mederacke. 2019. “Cholemic Nephropathy Causes Acute Kidney Injury and Is Accompanied by Loss of Aquaporin 2 in Collecting Ducts.” Hepatology 69(5):2107–19. doi: 10.1002/hep.30499.

Bravo, María Carmen, Paloma López-Ortego, Laura Sánchez, Rosario Madero, Fernando Cabañas, Armin Koch, Héctor Rojas-Anaya, Heike Rabe, and Adelina Pellicer. 2019. “Validity of Biomarkers of Early Circulatory Impairment to Predict Outcome: A Retrospective Analysis.” Frontiers in Pediatrics 7(MAY). doi: 10.3389/fped.2019.00212.

Byng, Danalyn, Johanna I. Lutter, Margarethe E. Wacker, Rudolf A. Jörres, Xiaofei Liu, Stefan Karrasch, Holger Schulz, Claus F. Vogelmeier, and Rolf Holle. 2019. “Determinants of Healthcare Utilization and Costs in COPD Patients: First Longitudinal Results from the German COPD Cohort COSYCONET.” International Journal of Chronic Obstructive Pulmonary Disease Volume 14:1423–39. doi: 10.2147/COPD.S201899.

Häckl, Sebastian, Armin Koch, and Florian Lasch. 2019. “Empirical Evaluation of the Implementation of the EMA Guideline on Missing Data in Confirmatory Clinical Trials: Specification of Mixed Models for Longitudinal Data in Study Protocols.” Pharmaceutical Statistics 18(6):636–44. doi: 10.1002/pst.1964.

Hemmings, Robert, and Armin Koch. 2019. “Commentary on: Subgroup Analysis and Interpretation for Phase 3 Confirmatory Trials: White Paper of the EFSPI/PSI Working Group on Subgroup Analysis by Dane, Spencer, Rosenkranz, Lipkovich, and Parke.” Pharmaceutical Statistics 18(2):140–44. doi: 10.1002/pst.1935.

Heusser, Karsten, Jens Tank, Olaf Holz, Marcus May, Julia Brinkmann, Stefan Engeli, André Diedrich, Theodor Framke, Armin Koch, Anika Großhennig, A. H. Jan Danser, Fred C. G. J. Sweep, Christoph Schindler, Katharina Schwarz, Norbert Krug, Jens Jordan, and Jens M. Hohlfeld. 2019. “Ultrafine Particles and Ozone Perturb Norepinephrine Clearance Rather than Centrally Generated Sympathetic Activity in Humans.” Scientific Reports 9(1):3641. doi: 10.1038/s41598-019-40343-w.

Hinken, Lukas, Hannelore Willenborg, Lukas Aguirre Dávila, and Dorothea Daentzer. 2019. “Outcome Analysis of Molding Helmet Therapy Using a Classification for Differentiation between Plagiocephaly, Brachycephaly and Combination of Both.” Journal of Cranio-Maxillofacial Surgery 47(5):720–25. doi: 10.1016/j.jcms.2019.01.011.

Kendall, Bruce E., Masami Fujiwara, Jasmin Diaz-Lopez, Sandra Schneider, Jakob Voigt, and Sören Wiesner. 2019. “Persistent Problems in the Construction of Matrix Population Models.” Ecological Modelling 406:33–43. doi: 10.1016/j.ecolmodel.2019.03.011.

Lasch, Florian, Kristina Weber, and Armin Koch. 2019. “Commentary: On the Levels of Patient Selection in Registry-Based Randomized Controlled Trials.” Trials 20(1):100. doi: 10.1186/s13063-019-3214-x.

May, Marcus, Theodor Framke, Bernd Junker, Carsten Framme, Amelie Pielen*, and Christoph Schindler*. 2019. “How and Why SGLT2 Inhibitors Should Be Explored as Potential Treatment Option in Diabetic Retinopathy: Clinical Concept and Methodology.” Therapeutic Advances in Endocrinology and Metabolism 10:204201881989188. doi: 10.1177/2042018819891886.

Trudzinski, Franziska C., Mohamad Alqudrah, Albert Omlor, Stephen Zewinger, Danilo Fliser, Timotheus Speer, Frederik Seiler, Frank Biertz, Armin Koch, Claus Vogelmeier, Tobias Welte, Henrik Watz, Benjamin Waschki, Sebastian Fähndrich, Rudolf Jörres, and Robert Bals. 2019. “Consequences of Chronic Kidney Disease in Chronic Obstructive Pulmonary Disease.” Respiratory Research 20(1):151. doi: 10.1186/s12931-019-1107-x.

Wedemeyer, Heiner, Cihan Yurdaydin, Svenja Hardtke, Florin Alexandru Caruntu, Manuela G. Curescu, Kendal Yalcin, Ulus S. Akarca, Selim Gürel, Stefan Zeuzem, Andreas Erhardt, Stefan Lüth, George V. Papatheodoridis, Onur Keskin, Kerstin Port, Monica Radu, Mustafa K. Celen, Ramazan Idilman, Kristina Weber, Judith Stift, Ulrike Wittkop, Benjamin Heidrich, Ingmar Mederacke, Heiko von der Leyen, Hans Peter Dienes, Markus Cornberg, Armin Koch, and Michael P. Manns. 2019. “Peginterferon Alfa-2a plus Tenofovir Disoproxil Fumarate for Hepatitis D (HIDIT-II): A Randomised, Placebo Controlled, Phase 2 Trial.” The Lancet Infectious Diseases 19(3):275–86. doi: 10.1016/S1473-3099(18)30663-7.

  • 2018

Bender, Ralf, Tim Friede, Armin Koch, Oliver Kuss, Peter Schlattmann, Guido Schwarzer, and Guido Skipka. 2018. “Methods for Evidence Synthesis in the Case of Very Few Studies.” Research Synthesis Methods 9(3):382–92. doi: 10.1002/jrsm.1297.

Gutberlet, Marcel, Till F. Kaireit, Andreas Voskrebenzev, Florian Lasch, Julia Freise, Tobias Welte, Frank Wacker, Jens M. Hohlfeld, and Jens Vogel-Claussen. 2018. “Free-Breathing Dynamic 19 F Gas MR Imaging for Mapping of Regional Lung Ventilation in Patients with COPD.” Radiology 286(3):1040–51. doi: 10.1148/radiol.2017170591.

Lingner, Heidrun, Heike Buhr-Schinner, Stefan Hummel, Jochen van der Meyden, Anika Grosshennig, Daniel Nowik, and Konrad Schultz. 2018. “Short-Term Effects of a Multimodal 3-Week Inpatient Pulmonary Rehabilitation Programme for Patients with Sarcoidosis: The ProKaSaRe Study.” Respiration 95(5):343–53. doi: 10.1159/000486964.

Lingner, Heidrun, Lena Blase, Anika Großhennig, and Guido Schmiemann. 2018. “Manual Therapy Applied by General Practitioners for Nonspecific Low Back Pain: Results of the ManRück Pilot-Study.” Chiropractic & Manual Therapies 26(1):39. doi: 10.1186/s12998-018-0202-2.

Weber, Kristina, Florian Lasch, and Armin Koch. 2018. “New Research Strategy with Ambiguous Implications: A Comment on ‘Planning Future Studies Based on the Conditional Power of a Meta-Analysis.’” Statistics in Medicine 37(8):1402–4. doi: 10.1002/sim.7595.

Weber, Kristina, Rob Hemmings, and Armin Koch. 2018. “How to Use Prior Knowledge and Still Give New Data a Chance?” Pharmaceutical Statistics 17(4):329–41. doi: 10.1002/pst.1862.

  • 2017

Hasdemir DB, Aguirre Davila L, Schweitzer N, Meyer BC, Koch A, Vogel A, Wacker F, Rodt T (2017): Evaluation of CT Vascularization Patterns for Survival Prognosis in Patients With Hepatocellular Carcinoma Treated by Conventional TACE. Diagn Interv Radiol 2017; 23: 217-222. DOI: 10.5152/dir.2016.16006

Schweitzer N, Fischer M, Kirstein MM, Berhane S, Kottas M, Sinn M, Gonzalez-Carmona MA, Balta Z, Weismuller TJ, Strassburg CP, Reineke-Plaass T, Bektas H, Manns MP, Johnson P, Weinmann A, Vogel A (2017): Risk estimation for biliary tract cancer: Development and validation of a prognostic store. Liver Int. 2017 Dec;37(12):1852-1860. doi: 10.1111/liv.13517. Epub 2017 Jul 28.

Weber K, Lasch F, Koch A. New research strategy with ambiguous implications: A comment on 'Planning future studies based on the conditional power of a meta-analysis' , Statistics in Medicine, accepted, DOI: 10.1002/sim.7595.

Wacker ME, Kitzing K, Jörres RA, Leidl R, Schulz H, Karrasch S, Karch A, Koch A, Vogelmeier CF, Holle R. The contribution of symptoms and comorbidities to the economic impact of COPD: an analysis of the German COSYCONET cohort.  Int J Chron Obstruct Pulmon Dis. 2017 Dec 4;12:3437-3448. doi: 10.2147/COPD.S141852.

Smid DE, Franssen FME, Gonik M, Miravitlles M, Casanova C, Cosio BG, de Lucas-Ramos P, Marin JM, Martinez C, Mir I, Soriano JB, de Torres JP, Agusti A, Atalay NB, Billington J, Boutou AK, Brighenti-Zogg S, Chaplin E, Coster S, Dodd JW, Dürr S, Fernandez-Villar A, Groenen MTJ, Guimarães M, Hejduk K, Higgins V, Hopkinson NS, Horita N, Houben-Wilke S, Janssen DJA, Jehn M, Joerres R, Karch A, Kelly JL, Kim YI, Kimura H, Koblizek V, Kocks JH, Kon SSC, Kwon N, Ladeira I, Lee SD, Leuppi JD, Locantore N, Lopez-Campos JL, D-C Man W, Maricic L, Mendoza L, Miedinger D, Mihaltan F, Minami S, van der Molen T, Murrells TJ, Nakken N, Nishijima Y, Norman IJ, Novotna B, O'Donnell DE, Ogata Y, Pereira ED, Piercy J, Price D, Pothirat C, Raghavan N, Ringbaek T, Sajkov D, Sigari N, Singh S, Small M, da Silva GF, Tanner RJ, Tsiligianni IG, Tulek B, Tzanakis N, Vanfleteren LEGW, Watz H, Webb KA, Wouters EFM, Xie GG, Yoshikawa M, Spruit MA. Redefining Cut-Points for High Symptom Burden of the Global Initiative for Chronic Obstructive Lung Disease Classification in 18,577 Patients With Chronic Obstructive Pulmonary Disease. J Am Med Dir Assoc. 2017 Dec 1; 18(12):1097.e11-1097.e24. doi: 10.1016/j.jamda.2017.09.003.

  • 2016

Abbas, M., S. Steffens, M. Bellut, H. Eggers, A. Großhennig, J. U. Becker, G. Wegener, A. J. Schrader, V. Grünwald, and P. Ivanyi. 2016. “Intratumoral Expression of Programmed Death Ligand 1 (PD-L1) in Patients with Clear Cell Renal Cell Carcinoma (CcRCC).” Medical Oncology 33(7):80. doi: 10.1007/s12032-016-0794-0.

Abbas, Mahmoud, Sandra Steffens, Maria Bellut, Jan U. Becker, Anika Großhennig, Hendrik Eggers, Gerd Wegener, Markus A. Kuczyk, Hans H. Kreipe, Viktor Grünwald, Andres J. Schrader, and Philipp Ivanyi. 2016. “Do Programmed Death 1 (PD-1) and Its Ligand (PD-L1) Play a Role in Patients with Non-Clear Cell Renal Cell Carcinoma?” Medical Oncology 33(6):59. doi: 10.1007/s12032-016-0770-8.

Bormann, Kai Hendrik, Kristina Weber, Heike Kloppenburg, Armin Koch, Peter Meiser, and Nils Claudius Gellrich. 2016. “Perioperative Bromelain Therapy after Wisdom Teeth Extraction – A Randomized, Placebo-Controlled, Double-Blinded, Three-Armed, Cross-Over Dose-Finding Study.” Phytotherapy Research 30(12):2012–19. doi: 10.1002/ptr.5707.

Derlin, Thorsten, Johannes Thiele, Desiree Weiberg, James T. Thackeray, Klaus Püschel, Hans Jürgen Wester, Lukas Aguirre Dávila, Axel Larena-Avellaneda, Günter Daum, Frank M. Bengel, and Udo Schumacher. 2016. “Evaluation of 68Ga-Glutamate Carboxypeptidase II Ligand Positron Emission Tomography for Clinical Molecular Imaging of Atherosclerotic Plaque Neovascularization.” Arteriosclerosis, Thrombosis, and Vascular Biology 36(11):2213–19. doi: 10.1161/ATVBAHA.116.307701.

Deterding, Katja, Norbert Grüner, Peter Buggisch, Peter R. Galle, Ulrich Spengler, Holger Hinrichsen, Thomas Berg, Andrej Potthoff, Anika Großhennig, Armin Koch, Helmut Diepolder, Stefan Lüth, Sandra Feyerabend, Maria C. Jung, Magdalena Rogalska-Taranta, Verena Schlaphoff, Markus Cornberg, Michael P. Manns, Heiner Wedemeyer, and Johannes Wiegand. 2016. “Symptoms of Anxiety and Depression Are Frequent in Patients with Acute Hepatitis C and Are Not Associated with Disease Severity.” European Journal of Gastroenterology and Hepatology 28(2):187–92. doi: 10.1097/MEG.0000000000000517.

Heusser, Karsten, Jens Tank, Julia Brinkmann, Christoph Schroeder, Marcus May, Anika Großhennig, Daniela Wenzel, André Diedrich, Fred C. G. J. Sweep, Heidrun Mehling, Friedrich C. Luft, and Jens Jordan. 2016. “Preserved Autonomic Cardiovascular Regulation with Cardiac Pacemaker Inhibition: A Crossover Trial Using High-Fidelity Cardiovascular Phenotyping.” Journal of the American Heart Association 5(1). doi: 10.1161/JAHA.115.002674.

Höhn, Matthias, Ute Von Jan, Theodor Framke, and Urs Vito Albrecht. 2016. “Classification of Health Related Applications.” Pp. 139–42 in Studies in Health Technology and Informatics. Vol. 226.

Hueper, Katja, Abedalrazag A. Khalifa, Jan H. Bräsen, Van Dai Vo Chieu, Marcel Gutberlet, Sabine Wintterle, Frank Lehner, Nicolas Richter, Matti Peperhove, Susanne Tewes, Kristina Weber, Hermann Haller, Frank Wacker, Wilfried Gwinner, Faikah Gueler, and Dagmar Hartung. 2016. “Diffusion-Weighted Imaging and Diffusion Tensor Imaging Detect Delayed Graft Function and Correlate with Allograft Fibrosis in Patients Early after Kidney Transplantation.” Journal of Magnetic Resonance Imaging 44(1):112–21. doi: 10.1002/jmri.25158.

Jakubovski, Ewgeni, Cornelia Reichert, Annika Karch, Nadine Buddensiek, Daniel Breuer, and Kirsten Müller-Vahl. 2016. “The ONLINE-TICS Study Protocol: A Randomized Observer-Blind Clinical Trial to Demonstrate the Efficacy and Safety of Internet-Delivered Behavioral Treatment for Adults with Chronic Tic Disorders.” Frontiers in Psychiatry 7(JUN). doi: 10.3389/fpsyt.2016.00119.

Kammer, Jessica, Stefan Ziesing, Lukas Aguirre Davila, Eva Bültmann, Sabine Illsinger, Anibh M. Das, Dieter Haffner, and Hans Hartmann. 2016. “Neurological Manifestations of Mycoplasma Pneumoniae Infection in Hospitalized Children and Their Long-Term Follow-Up.” Neuropediatrics 47(5):308–17. doi: 10.1055/s-0036-1584325.

Karch, Annika, Armin Koch, and Viktor Grünwald. 2016. “A Phase II Trial Comparing Pazopanib with Doxorubicin as First-Line Treatment in Elderly Patients with Metastatic or Advanced Soft Tissue Sarcoma (EPAZ): Study Protocol for a Randomized Controlled Trial.” Trials 17(1). doi: 10.1186/s13063-016-1434-x.

Karch, Annika, Armin Koch, Antonia Zapf, Inga Zerr, and André Karch. 2016. “Partial Verification Bias and Incorporation Bias Affected Accuracy Estimates of Diagnostic Studies for Biomarkers That Were Part of an Existing Composite Gold Standard.” Journal of Clinical Epidemiology 78:73–82. doi: 10.1016/j.jclinepi.2016.03.022.

Karch, Annika, Claus Vogelmeier, Tobias Welte, Robert Bals, Hans Ulrich Kauczor, Jürgen Biederer, Joachim Heinrich, Holger Schulz, Sven Gläser, Rolf Holle, Henrik Watz, Stephanie Korn, Nina Adaskina, Frank Biertz, Charlotte Vogel, Jørgen Vestbo, Emiel F. M. Wouters, Klaus Friedrich Rabe, Sandra Söhler, Armin Koch, and Rudolf A. Jörres. 2016. “The German COPD Cohort COSYCONET: Aims, Methods and Descriptive Analysis of the Study Population at Baseline.” Respiratory Medicine 114:27–37. doi: 10.1016/j.rmed.2016.03.008.

Koch, Armin, and Yvonne Ziert. 2016. “Does It Help That Efficacy Has Been Proven Once We Start Discussing (Added) Benefit?” Biometrical Journal 58(1):89–103. doi: 10.1002/bimj.201400017.

Leo, Fabian, Stephan Bartels, Lavinia Mägel, Theodor Framke, Guntram Büsche, Danny Jonigk, Matthias Christgen, Ulrich Lehmann, and Hans Kreipe. 2016. “Prognostic Factors in the Myoepithelial-like Spindle Cell Type of Metaplastic Breast Cancer.” Virchows Archiv 469(2):191–201. doi: 10.1007/s00428-016-1950-9.

Lucke, Tanja, Ronald Herrera, Margarethe Wacker, Rolf Holle, Frank Biertz, Dennis Nowak, Rudolf M. Huber, Sandra Söhler, Claus Vogelmeier, Joachim H. Ficker, Harald Mückter, and Rudolf A. Jörres. 2016. “Systematic Analysis of Self-Reported Comorbidities in Large Cohort Studies - A Novel Stepwise Approach by Evaluation of Medication.” PLoS ONE 11(10). doi: 10.1371/journal.pone.0163408.

Lueer, K., H. Biller, A. Casper, H. Windt, M. Mueller, P. Badorrek, D. Haefner, T. Framke, A. Koch, H. Ziehr, N. Krug, W. Koch, and J. M. Hohlfeld. 2016. “Safety, Efficacy and Repeatability of a Novel House Dust Mite Allergen Challenge Technique in the Fraunhofer Allergen Challenge Chamber.” Allergy: European Journal of Allergy and Clinical Immunology 71(12):1693–1700. doi: 10.1111/all.12947.

Neubert, Nils, P. M. Vogt, M. May, M. Boyce, S. Koenneker, E. Budde, and A. Jokuszies. 2016. “Does an Early and Aggressive Combined Wrapping and Dangling Procedure Affect the Clinical Outcome of Lower Extremity Free Flaps? - A Randomized Controlled Prospective Study Using Microdialysis Monitoring.” Journal of Reconstructive Microsurgery 32(4):262–70. doi: 10.1055/s-0035-1568882.

Paparoupa, Maria, Loukia Spineli, Theodor Framke, Huy Ho, Frank Schuppert, and Adrian Gillissen. 2016. “Pulmonary Embolism in Pneumonia: Still a Diagnostic Challenge? Results of a Case-Control Study in 100 Patients.” Disease Markers. doi: 10.1155/2016/8682506.

Rios, Nelmin, Nina Adaskina, Cornelia Frömke, Frank Papendorf, Cordula Schippert, Armin Koch, Peter Hillemanns, and Tjoung Won Park-Simon. 2016. “The Benefit of Baseline Staging-Risk Assessment of Distant Breast Cancer Metastases by Tumor Stage.” Anticancer Research 36(9):4909–14. doi: 10.21873/anticanres.11056.

Schäfer, T., M. Klintschar, R. Lichtinghagen, I. Plagemann, A. Smith, E. Budde, and L. Hagemeier. 2016. “Xanthochromia of the Skull Bone Associated with HbA1c.” Forensic Science International 260:54–58. doi: 10.1016/j.forsciint.2015.12.030.

Scheper, Verena, Melanie Leifholz, Heiko von der Leyen, Miriam Keller, Ute Denkena, Armin Koch, Annika Karch, Josef Miller, and Thomas Lenarz. 2016. “ACEMg-Mediated Hearing Preservation in Cochlear Implant Patients Receiving Different Electrode Lengths (PROHEARING): Study Protocol for a Randomized Controlled Trial.” Trials 17(1). doi: 10.1186/s13063-016-1526-7.

Schwarz, Anke, Silvia Linnenweber-Held, Albert Heim, Theodor Framke, Hermann Haller, and Corinna Schmitt. 2016. “Viral Origin, Clinical Course, and Renal Outcomes in Patients with BK Virus Infection after Living-Donor Renal Transplantation.” Transplantation 100(4):844–53. doi: 10.1097/TP.0000000000001066.

Volk, V., A. Schneider, L. M. Spineli, A. Grosshennig, and R. Stripecke. 2016. “The Gender Gap: Discrepant Human T-Cell Reconstitution after Cord Blood Stem Cell Transplantation in Humanized Female and Male Mice.” Bone Marrow Transplantation 51(4):596–97.

Wacker, M. E., R. A. Jörres, H. Schulz, J. Heinrich, S. Karrasch, A. Karch, A. Koch, A. Peters, R. Leidl, C. Vogelmeier, and R. Holle. 2016. “Direct and Indirect Costs of COPD and Its Comorbidities: Results from the German COSYCONET Study.” Respiratory Medicine 111:39–46. doi: 10.1016/j.rmed.2015.12.001.

Wacker, Margarethe E., Rudolf A. Jörres, Annika Karch, Armin Koch, Joachim Heinrich, Stefan Karrasch, Holger Schulz, Annette Peters, Sven Gläser, Ralf Ewert, Sebastian E. Baumeister, Claus Vogelmeier, Reiner Leidl, and Rolf Holle. 2016. “Relative Impact of COPD and Comorbidities on Generic Health-Related Quality of Life: A Pooled Analysis of the COSYCONET Patient Cohort and Control Subjects from the KORA and SHIP Studies.” Respiratory Research 17(1). doi: 10.1186/s12931-016-0401-0.

Wacker, Margarethe E., Rudolf A. Jörres, Annika Karch, Sarah Wilke, Joachim Heinrich, Stefan Karrasch, Armin Koch, Holger Schulz, Henrik Watz, Reiner Leidl, Claus Vogelmeier, and Rolf Holle. 2016. “Assessing Health-Related Quality of Life in COPD: Comparing Generic and Disease-Specific Instruments with Focus on Comorbidities.” BMC Pulmonary Medicine 16(1). doi: 10.1186/s12890-016-0238-9.

  • 2015

Behrens, Katharina, Melina A. Del Pozo, Anika Großhennig, Marcel Sieberer, and Iris T. Graef-Calliess. 2015. “How Much Orientation towards the Host Culture Is Healthy? Acculturation Style as Risk Enhancement for Depressive Symptoms in Immigrants.” International Journal of Social Psychiatry 61(5):498–505. doi: 10.1177/0020764014560356.

Budde, S., Y. Noll, V. Zieglschmid, C. Schroeder, A. Koch, and H. Windhagen. 2015. “Determination of the Efficacy of EVICELTM on Blood Loss in Orthopaedic Surgery after Total Knee Replacement: Study Protocol for a Randomised Controlled Trial.” Trials 16(1). doi: 10.1186/s13063-015-0822-y.

Doose, Michael, Marc Ziegenbein, Olaf Hoos, Dominik Reim, Wojciech Stengert, Niklas Hoffer, Charlotte Vogel, Yvonne Ziert, and Marcel Sieberer. 2015. “Self-Selected Intensity Exercise in the Treatment of Major Depression: A Pragmatic RCT.” International Journal of Psychiatry in Clinical Practice 19(4):267–76. doi: 10.3109/13651501.2015.1082599.

Fischer, Friederike, Rüdiger Klapdor, Susanne Gruessner, Yvonne Ziert, Peter Hillemanns, and Hermann Hertel. 2015. “Radiofrequency Endometrial Ablation for the Treatment of Heavy Menstrual Bleeding among Women at High Surgical Risk.” International Journal of Gynecology and Obstetrics 131(2):123–28. doi: 10.1016/j.ijgo.2015.05.028.

Gonnermann, A., M. Kottas, and Armin Koch. 2015. “Biometrische Entscheidungsunterstützung in Zulassung Und Nutzenbewertung Am Beispiel Der Implikationen von Heterogenen Ergebnissen in Untergruppen Der Studienpopulation.” Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 58(3):274–82. doi: 10.1007/s00103-014-2105-2.

Gonnermann, Andrea, Theodor Framke, Anika Großhennig, and Armin Koch. 2015. “No Solution yet for Combining Two Independent Studies in the Presence of Heterogeneity.” Statistics in Medicine 34(16):2476–80. doi: 10.1002/sim.6473.

Grünwald, Viktor, U. Keilholz, A. Boehm, O. Guntinas-Lichius, B. Hennemann, H. J. Schmoll, P. Ivanyi, M. Abbas, U. Lehmann, A. Koch, A. Karch, A. Zörner, and T. C. Gauler. 2015. “TEMHEAD: A Single-Arm Multicentre Phase II Study of Temsirolimus in Platin- and Cetuximab Refractory Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN) of the German SCCHN Group (AIO).” Annals of Oncology 26(3):561–67. doi: 10.1093/annonc/mdu571.

Heidrich, Benjamin, Hans Jörg Cordes, Hartwig Klinker, Bernd Möller, Uwe Naumann, Martin Rössle, Michael R. Kraus, Klaus H. Böker, Christoph Roggel, Marcus Schuchmann, Albrecht Stoehr, Andreas Trein, Svenja Hardtke, Andrea Gonnermann, Armin Koch, Heiner Wedemeyer, Michael P. Manns, and Markus Cornberg. 2015. “Treatment Extension of Pegylated Interferon Alpha and Ribavirin Does Not Improve SVR in Patients with Genotypes 2/3 without Rapid Virological Response (OPTEX Trial): A Prospective, Randomized, Two-Arm, Multicentre Phase IV Clinical Trial.” PLoS ONE 10(6). doi: 10.1371/journal.pone.0128069.

Hong, Bujung, Frank Biertz, Peter Raab, Dirk Scheinichen, Philipp Ertl, Anika Grosshennig, Makoto Nakamura, Elvis J. Hermann, Josef M. Lang, Heinrich Lanfermann, and Joachim K. Krauss. 2015. “Normobaric Hyperoxia for Treatment of Pneumocephalus after Posterior Fossa Surgery in the Semisitting Position: A Prospective Randomized Controlled Trial.” PLoS ONE 10(5). doi: 10.1371/journal.pone.0125710.

Hueper, Katja, Faikah Gueler, Jan Hinrich Bräsen, Marcel Gutberlet, Mi Sun Jang, Frank Lehner, Nicolas Richter, Nils Hanke, Matti Peperhove, Petros Martirosian, Susanne Tewes, Van Dai Vo Chieu, Anika Großhennig, Hermann Haller, Frank Wacker, Wilfried Gwinner, and Dagmar Hartung. 2015. “Functional MRI Detects Perfusion Impairment in Renal Allografts with Delayed Graft Function.” American Journal of Physiology - Renal Physiology 308(12):F1444–51. doi: 10.1152/ajprenal.00064.2015.

Lingner, Heidrun, Anika Großhennig, Kathrin Flunkert, Heike Buhr-Schinner, Rolf Heitmann, Ulrich Tönnesmann, Jochen van der Meyden, and Konrad Schultz. 2015. “ProKaSaRe Study Protocol: A Prospective Multicenter Study of Pulmonary Rehabilitation of Patients With Sarcoidosis.” JMIR Research Protocols 4(4):e134. doi: 10.2196/resprot.4948.

Manolis, Efthymios, Armin Koch, Dieter Deforce, and Spiros Vamvakas. 2015. “The European Medicines Agency Experience with Biomarker Qualification.” Methods in Molecular Biology 1243:255–72. doi: 10.1007/978-1-4939-1872-0_15.

Rohde, Gernot G. U., Armin Koch, Tobias Welte, M. Dreher, C. Cornelissen, W. Knüppel, S. Dressel, T. Bauer, T. Sabha, W. Pankow, A. Lies, A. de Roux, N. Dallwitz, O. Pociuli, P. Zierock, B. Hauptmeier, D. Wehde, C. Herzmann, C. Lange, B. Schaaf, C. Teipel, G. Höffken, M. Kolditz, M. Idzko, B. Seuthe, S. Gläser, R. Ewert, G. Nilius, K. J. Franke, C. Weiss, T. Zelniker, T. Köhnlein, J. Freise, S. Andreas, P. Hammerl, M. Pletz, S. Hagel, K. Dalhoff, D. Drömann, H. Buschmann, R. Kröning, T. Schaberg, C. Göbel, W. Randerath, C. Priegnitz, S. Stieglitz, S. Hagmeyer, K. Rasche, M. Leidag, G. Barten, W. Kröner, J. Naim, M. Abrahamczik, A. Koch, A. Gonnermann, D. Stichtenoth, H. Von Der Leyen, D. Breuer, M. Craul, T. Welte, N. Suttorp, S. Stenger, G. Rohde, M. Pletz, H. Schütte, J. Rupp, T. Illmann, M. Wallner, T. Illig, N. Klopp, and S. Bauer. 2015. “Randomized Double Blind Placebo-Controlled Study to Demonstrate That Antibiotics Are Not Needed in Moderate Acute Exacerbations of COPD - The ABACOPD Study.” BMC Pulmonary Medicine. doi: 10.1186/1471-2466-15-5.

Schmiemann, Guido, Lena Blase, Christoph Seeber, Stefanie Joos, Jost Steinhäuser, Stefanie Ernst, Anika Großhennig, Eva Hummers-Pradier, and Heidrun Lingner. 2015. “Manual Therapy by General Medical Practitioners for Nonspecific Low Back Pain in Primary Care: The Manrück Study Protocol of a Clinical Trial.” Journal of Chiropractic Medicine 14(1):39–45. doi: 10.1016/j.jcm.2015.02.003.

Schubert, Stephanie, Cordula Haas, Christine Bartsch, Mandana Mirshekarnejad, Sarah Kohrs, Irene Roettinger, Anika Grosshennig, Manfred Stuhrmann, Caroline Scholz, and Jörg Schmidtke. 2015. “Variants in TSPYL1 Are Not Associated with Sudden Infant Death Syndrome in a Cohort of Deceased Infants from Switzerland.” Molecular and Cellular Probes 29(1):31–34. doi: 10.1016/j.mcp.2014.10.006.

Tiede, Andreas, Robert Klamroth, Rüdiger E. Scharf, Ralf U. Trappe, Katharina Holstein, Angela Huth-Kühne, Saskia Gottstein, Ulrich Geisen, Joachim Schenk, Ute Scholz, Kristina Schilling, Peter Neumeister, Wolfgang Miesbach, Daniela Manner, Richard Greil, Charis Von Auer, Manuela Krause, Klaus Leimkühler, Ulrich Kalus, Jan Malte Blumtritt, Sonja Werwitzke, Eva Budde, Armin Koch, and Paul Knöbl. 2015. “Prognostic Factors for Remission of and Survival in Acquired Hemophilia A (AHA): Results from the GTH-AH 01/2010 Study.” Blood 125(7):1091–97. doi: 10.1182/blood-2014-07-587089.

Wonnemann, Meinolf, Cornelia Frömke, and Armin Koch. 2015. “Inflation of the Type i Error: Investigations on Regulatory Recommendations for Bioequivalence of Highly Variable Drugs.” Pharmaceutical Research 32(1):135–43. doi: 10.1007/s11095-014-1450-z.

Zapf, Antonia, Wilfried Gwinner, Annika Karch, Jochen Metzger, Hermann Haller, and Armin Koch. 2015. “Non-Invasive Diagnosis of Acute Rejection in Renal Transplant Patients Using Mass Spectrometry of Urine Samples - A Multicentre Phase 3 Diagnostic Accuracy Study.” BMC Nephrology. doi: 10.1186/s12882-015-0146-x.

  • 2014

Ahlenstiel-Grunow, Thurid, Armin Koch, Anika Großhennig, Cornelia Frömke, Martina Sester, Urban Sester, Christoph Schröder, and Lars Pape. 2014. “A Multicenter, Randomized, Open-Labeled Study to Steer Immunosuppressive and Antiviral Therapy by Measurement of Virus (CMV, ADV, HSV)-Specific T Cells in Addition to Determination of Trough Levels of Immunosuppressants in Pediatric Kidney Allograft Recip.” Trials 15(1). doi: 10.1186/1745-6215-15-324.

Calle Serrano, B., A. Großhennig, M. Homs, B. Heidrich, A. Erhardt, K. Deterding, J. Jaroszewicz, B. Bremer, A. Koch, M. Cornberg, M. P. Manns, M. Buti, and H. Wedemeyer. 2014. “Development and Evaluation of a Baseline-Event-Anticipation Score for Hepatitis Delta.” Journal of Viral Hepatitis 21(11):e154–63. doi: 10.1111/jvh.12251.

Gillmann, Hans Jörg, Antje Meinders, Anika Großhennig, Jan Larmann, Christoph Bünte, Simone Calmer, Bianca Sahlmann, Saad Rustum, Thomas Aper, Ralf Lichtinghagen, Armin Koch, Omke E. Teebken, and Gregor Theilmeier. 2014. “Perioperative Levels and Changes of High-Sensitivity Troponin T Are Associated with Cardiovascular Events in Vascular Surgery Patients.” Critical Care Medicine 42(6):1498–1506. doi: 10.1097/CCM.0000000000000249.

Koch, Armin, and Theodor Framke. 2014. “Reliably Basing Conclusions on Subgroups of Randomized Clinical Trials.” Journal of Biopharmaceutical Statistics 24(1):42–57. doi: 10.1080/10543406.2013.856020.

Kreuzer, Martin, Jenny Prüfe, Dirk Bethe, Charlotte Vogel, Anika Großhennig, Armin Koch, Martina Oldhafer, Marie-Luise Dierks, Urs-Vito Albrecht, Silvia Müther, Reinhard Brunkhorst, and Lars Pape. 2014. “The TRANSNephro-Study Examining a New Transition Model for Post-Kidney Transplant Adolescents and an Analysis of the Present Health Care: Study Protocol for a Randomized Controlled Trial.” Trials 15(1):505. doi: 10.1186/1745-6215-15-505.

Schaumann, Frank, Cornelia Frömke, Dorothea Dijkstra, Francesca Alessandrini, Horst Windt, Erwin Karg, Meike Müller, Carla Winkler, Armin Braun, Armin Koch, Jens M. Hohlfeld, Heidrun Behrendt, Otmar Schmid, Wolfgang Koch, Holger Schulz, and Norbert Krug. 2014. “Effects of Ultrafine Particles on the Allergic Inflammation in the Lung of Asthmatics: Results of a Double-Blinded Randomized Cross-over Clinical Pilot Study.” Particle and Fibre Toxicology 11(1). doi: 10.1186/s12989-014-0039-3.

Schrem, Harald, Anna Luise Platsakis, Alexander Kaltenborn, Armin Koch, Courtney Metz, Marc Barthold, Christian Krauth, Volker Amelung, Felix Braun, Thomas Becker, Jürgen Klempnauer, and Benedikt Reichert. 2014. “Value and Limitations of the BAR-Score for Donor Allocation in Liver Transplantation.” Langenbeck’s Archives of Surgery 399(8):1011–19. doi: 10.1007/s00423-014-1247-x.

Schroeder, C., K. Heusser, A. A. Zoerner, A. Großhennig, D. Wenzel, M. May, F. C. G. J. Sweep, H. Mehling, F. C. Luft, J. Tank, and J. Jordan. 2014. “Pacemaker Current Inhibition in Experimental Human Cardiac Sympathetic Activation: A Double-Blind, Randomized, Crossover Study.” Clinical Pharmacology and Therapeutics 95(6):601–7. doi: 10.1038/clpt.2014.25.

  • 2013

  • 2012

  • 2011