~ in Überarbeitung ~

  • 2021

Ahlenstiel-Grunow, Thurid, Xiaofei Liu, Raphael Schild, Jun Oh, Christina Taylan, Lutz T. Weber, Hagen Staude, Murielle Verboom, Christoph Schröder, Ruxandra Sabau, Anika Großhennig, and Lars Pape. 2021. “Steering Transplant Immunosuppression by Measuring Virus-Speci Fi c T Cell Levels : The Randomized , Controlled IVIST Trial.” J Am Soc Nephrol 32(2):502–16. doi: 10.1681/ASN.2020050645.

Burger, Hans Ulrich, Christoph Gerlinger, Chris Harbron, Armin Koch, Martin Posch, Justine Rochon, and Anja Schiel. 2021. “The Use of External Controls: To What Extent Can It Currently Be Recommended?” Pharmaceutical Statistics (January):pst.2120. doi: 10.1002/pst.2120.

Lasch, Florian, Lorenzo Guizzaro, Armin Koch, and Lukas Aguirre Dávila. 2021. “Potential Impact of COVID-19 on Ongoing Clinical Trials : A Simulation Study with the Neurological Yale Global Tic Severity Scale Based on the CANNA-TICS Study.” Pharmaceutical Statistics (January):1–17. doi: 10.1002/pst.2100.

Pellicer, Adelina, Ramón Fernández, Vincent Jullien, Clare Gleeson, María Carmen Bravo, Paloma López Ortego, Laura Sánchez, Marta Ybarra, Héctor Rojas-Anaya, Fernando Cabañas, Armin Koch, Andrea Smith, and Heike Rabe. 2021. “Pharmacokinetic Study (Phase I−II) of a New Dobutamine Formulation in Preterm Infants Immediately after Birth.” Pediatric Research 89(4):981–86. doi: 10.1038/s41390-020-1009-0.

  • 2020

Aguirre Dávila, Lukas, Armin Koch, and Florian Lasch. 2020. “Randomization versus Real-World Evidence.” New England Journal of Medicine 383(4):e21. doi: 10.1056/nejmc2020020.

Bunk, Daniel, Michael Eisenburger, Sebastian Häckl, Jörg Eberhard, Meike Stiesch, and Jasmin Grischke. 2020. “The Effect of Adjuvant Oral Irrigation on Self‐administered Oral Care in the Management of Peri‐implant Mucositis: A Randomized Controlled Clinical Trial.” Clinical Oral Implants Research 31(10):946–58. doi: 10.1111/clr.13638.

Clausen, Jan-Dierk, Niclas Nahen, Hauke Horstmann, Florian Lasch, Werner Krutsch, Christian Krettek, and Thomas Sanjay Weber-Spickschen. 2020. “Improving Maximal Strength in the Initial Postoperative Phase After Anterior Cruciate Ligament Reconstruction Surgery: Randomized Controlled Trial of an App-Based Serious Gaming Approach.” JMIR Serious Games 8(1):e14282. DOI:10.2196/14282.

Cornberg, Markus, Sven Pischke, Tobias Müller, Patrick Behrendt, Felix Piecha, Julia Benckert, Daniel Todt, Eike Steinmann, Armin Papkalla, Maria von Karpowitz, Armin Koch, Ansgar Lohse, Svenja Hardtke, Michael P. Manns, and Heiner Wedemeyer. 2020. “Sofosbuvir Monotherapy Fails to Achieve HEV RNA Elimination in Patients with Chronic Hepatitis E – The HepNet SofE Pilot Study.” Journal of Hepatology 73(3):696–99. doi: 10.1016/j.jhep.2020.05.020.

Großhennig, Anika, and Armin Koch. 2020. “COVID-19 Hits a Trial: Arguments against Hastily Deviating from the Plan.” Contemporary Clinical Trials 98:106155.doi: 10.1016/j.cct.2020.106155.

Grünwald, Viktor, Annika Karch, Markus Schuler, Patrick Schöffski, Hans-Georg Kopp, Sebastian Bauer, Bernd Kasper, Lars H. Lindner, Jens-Marcus Chemnitz, Martina Crysandt, Alexander Stein, Björn Steffen, Stephan Richter, Gerlinde Egerer, Philipp Ivanyi, Silke Zimmermann, Xiaofei Liu, and Annegret Kunitz. 2020. “Randomized Comparison of Pazopanib and Doxorubicin as First-Line Treatment in Patients With Metastatic Soft Tissue Sarcoma Age 60 Years or Older: Results of a German Intergroup Study.” Journal of Clinical Oncology 38(30):3555–64. doi: 10.1200/JCO.20.00714.

Heinemann, Nele Carolin, Sabine Tischer-Zimmermann, Torge Christian Wittke, Julian Eigendorf, Arno Kerling, Theodor Framke, Anette Melk, Hans-Gert Heuft, Rainer Blasczyk, Britta Maecker-Kolhoff, and Britta Eiz-Vesper. 2020. “High-Intensity Interval Training in Allogeneic Adoptive T-Cell Immunotherapy – a Big HIT?” Journal of Translational Medicine 18(1):148.

Holstein, Katharina, Xiaofei Liu, Andrea Smith, Paul Knöbl, Robert Klamroth, Ulrich Geisen, Hermann Eichler, Wolfgang Miesbach, and Andreas Tiede. 2020. “Bleeding and Response to Hemostatic Therapy in Acquired Hemophilia A (AHA): Results from the GTH-AH 01/2010 Study.” Blood 136(3):279–87. doi: 10.1182/blood.2019003639.

Horstmann, Hauke, Pascal Medico, Florian Lasch, Werner Krutsch, and Thomas Sanjay Weber-Spickschen. 2020. “Simplified Measurement of Maximum Strength After Knee Surgery: Application-Based Knee-Training Device Compared to Isokinetic Testing.” Open Access Journal of Sports Medicine Volume 11:43–49. DOI: 10.2147/OAJSM.S214598.

Konrad, Simon, Theodor Framke, Eugen Kludt, Andreas Büchner, Thomas Lenarz, and Gerrit Paasche. 2020. “Do Impedance Changes Correlate With a Delayed Hearing Loss After Hybrid L24 Implantation?” Ear & Hearing Publish Ah. doi: 10.1097/AUD.0000000000000914.

Lasch, Florian, Annika Karch, Armin Koch, Thorsten Derlin, Andreas Voskrebenzev, Tawfik Moher Alsady, Marius M. Hoeper, Henning Gall, Fritz Roller, Sebastian Harth, Dagmar Steiner, Gabriele Krombach, Hossein Ardeschir Ghofrani, Fabian Rengier, Claus Peter Heußel, Ekkehard Grünig, Dietrich Beitzke, Marcus Hacker, Irene M. Lang, Jürgen Behr, Peter Bartenstein, Julien Dinkel, Kai-Helge Schmidt, Karl-Friedrich Kreitner, Thomas Frauenfelder, Silvia Ulrich, Okka W. Hamer, Michael Pfeifer, Christopher S. Johns, David G. Kiely, Andrew James Swift, Jim Wild, and Jens Vogel-Claussen. 2020. “Comparison of MRI and VQ-SPECT as a Screening Test for Patients With Suspected CTEPH: CHANGE-MRI Study Design and Rationale.” Frontiers in Cardiovascular Medicine 7:51. doi: 10.3389/fcvm.2020.00051.

Mederacke, Young-Seon, Martha M. Kirstein, Anika Großhennig, Silke Marhenke, Frauke Metzler, Michael P. Manns, Arndt Vogel, and Ingmar Mederacke. 2020. “The PNPLA3 Rs738409 GG Genotype Is Associated with Poorer Prognosis in 239 Patients with Autoimmune Hepatitis.” Alimentary Pharmacology & Therapeutics 51(11):1160–68. doi: 10.1111/apt.15722.

Plaass, Christian, Annika Karch, Armin Koch, Vivien Wiederhoeft, Sarah Ettinger, Leif Claassen, Kiriakos Daniilidis, Daiwei Yao, and Christina Stukenborg-Colsman. 2020. “Short Term Results of Dynamic Splinting for Hallux Valgus — A Prospective Randomized Study.” Foot and Ankle Surgery 26(2):146–50. doi: 10.1016/j.fas.2019.01.002.

Scheper, Verena, Melanie Schmidtheisler, Florian Lasch, Heiko von der Leyen, Armin Koch, Jana Schwieger, Andreas Büchner, Anke Lesinski-Schiedat, and Thomas Lenarz. 2020. “Randomized Placebo-Controlled Clinical Trial Investigating the Effect of Antioxidants and a Vasodilator on Overall Safety and Residual Hearing Preservation in Cochlear Implant Patients.” Trials 21(1):643. doi: 10.1186/s13063-020-04522-9.

Solbach, Philipp, Patrick Chhatwal, Sabrina Woltemate, Evelina Tacconelli, Michael Buhl, Ingo B. Autenrieth, Maria J. G. T. Vehreschild, Nathalie Jazmati, Markus Gerhard, Christoph K. Stein-Thoeringer, Jan Rupp, Kurt Ulm, Armin Ott, Florian Lasch, Armin Koch, Michael P. Manns, Sebastian Suerbaum, and Oliver Bachmann. 2020. “Microbiota-Associated Risk Factors for C. Difficile Acquisition in Hospitalized Patients: A Prospective, Multicentric Study.” Clinical Infectious Diseases. doi: 10.1093/cid/ciaa871.

Tenhunen, Olli, Florian Lasch, Anja Schiel, and Miia Turpeinen. 2020. “Single‐Arm Clinical Trials as Pivotal Evidence for Cancer Drug Approval: A Retrospective Cohort Study of Centralized European Marketing Authorizations Between 2010 and 2019.” Clinical Pharmacology & Therapeutics 108(3):653–60. doi: 10.1002/cpt.1965.

von Versen-Höynck, Frauke, Sebastian Häckl, Elif Seda Selamet Tierney, Kirk P. Conrad, Valerie L. Baker, and Virginia D. Winn. 2020. “Maternal Vascular Health in Pregnancy and Postpartum After Assisted Reproduction.” Hypertension 75(2):549–60. doi: 10.1161/HYPERTENSIONAHA.119.13779.

Westhoff-Bleck, Mechthild, Lotta Winter, Lukas Aguirre Davila, Christoph Herrmann-Lingen, Jens Treptau, Johann Bauersachs, Stefan Bleich, and Kai G. Kahl. 2020. “Diagnostic Evaluation of the Hospital Depression Scale (HADS) and the Beck Depression Inventory II (BDI-II) in Adults with Congenital Heart Disease Using a Structured Clinical Interview: Impact of Depression Severity.” European Journal of Preventive Cardiology 27(4):381–90. doi: 10.1177/2047487319865055.

  • 2019

Abeling, Tanja, Irina Scheffner, Annika Karch, Verena Broecker, Armin Koch, Hermann Haller, Anke Schwarz, and Wilfried Gwinner. 2019. “Risk Factors for Death in Kidney Transplant Patients: Analysis from a Large Protocol Biopsy Registry.” Nephrology Dialysis Transplantation 34(7):1171–81. doi: 10.1093/ndt/gfy131.

Aguirre Dávila, Lukas, Kristina Weber, Udo Bavendiek, Johann Bauersachs, Janet Wittes, Salim Yusuf, and Armin Koch. 2019. “Digoxin–Mortality: Randomized vs. Observational Comparison in the DIG Trial.” European Heart Journal 40(40):3336–41. doi: 10.1093/eurheartj/ehz395.

Albrecht, Urs-Vito, Theodor Framke, and Ute von Jan. 2019. “Quality Awareness and Its Influence on the Evaluation of App Meta-Information by Physicians: Validation Study.” JMIR MHealth and UHealth 7(11):e16442. doi: 10.2196/16442.

Alter, Peter, Henrik Watz, Kathrin Kahnert, Klaus F. Rabe, Frank Biertz, Ronald Fischer, Philip Jung, Jana Graf, Robert Bals, Claus F. Vogelmeier, and Rudolf A. Jörres. 2019. “Effects of Airway Obstruction and Hyperinflation on Electrocardiographic Axes in COPD.” Respiratory Research 20(1):61. doi: 10.1186/s12931-019-1025-y.

Baier, Claas, Ramin Ipaktchi, Frank Schwab, Andrea Smith, Xiaofei Liu, Ella Ebadi, Anne Limbourg, Tobias R. Mett, Franz-Christoph Bange, and Peter Maria Vogt. 2019. “Universal Decolonization with Octenidine: First Experiences in a Tertiary Burn Intensive Care Unit.” Burns Open 3(1):8–11. doi: 10.1016/j.burnso.2018.10.003.

Bavendiek, Udo, Dominik Berliner, Lukas Aguirre Dávila, Johannes Schwab, Lars Maier, Sebastian A. Philipp, Andreas Rieth, Ralf Westenfeld, Christopher Piorkowski, Kristina Weber, Anja Hänselmann, Maximiliane Oldhafer, Sven Schallhorn, Heiko von der Leyen, Christoph Schröder, Christian Veltmann, Stefan Störk, Michael Böhm, Armin Koch, Johann Bauersachs, Udo Bavendiek, Johann Bauersachs, Armin Koch, Heiko von der Leyen, Christian Veltmann, Michael Böhm, Stefan Störk, Ulrich Tebbe, Stephan von Haehling, Markus Haass, Stefan Anker, Paul Mohacsi, Gerhard Pölzl, Helmut Trampisch, Lukas Aguirre Dávila, Kristina Weber, Silke Zimmermann, and Barbara Neuhaus. 2019. “Rationale and Design of the DIGIT‐HF Trial (DIGitoxin to Improve OuTcomes in Patients with Advanced Chronic Heart Failure): A Randomized, Double‐blind, Placebo‐controlled Study.” European Journal of Heart Failure 21(5):676–84. doi: 10.1002/ejhf.1452.

Bräsen, Jan Hinrich, Young‐Seon Mederacke, Jessica Schmitz, Kateryna Diahovets, Abedalrazag Khalifa, Björn Hartleben, Fermín Person, Thorsten Wiech, Eric Steenbergen, Anika Großhennig, Michael P. Manns, Roland Schmitt, and Ingmar Mederacke. 2019. “Cholemic Nephropathy Causes Acute Kidney Injury and Is Accompanied by Loss of Aquaporin 2 in Collecting Ducts.” Hepatology 69(5):2107–19. doi: 10.1002/hep.30499.

Bravo, María Carmen, Paloma López-Ortego, Laura Sánchez, Rosario Madero, Fernando Cabañas, Armin Koch, Héctor Rojas-Anaya, Heike Rabe, and Adelina Pellicer. 2019. “Validity of Biomarkers of Early Circulatory Impairment to Predict Outcome: A Retrospective Analysis.” Frontiers in Pediatrics 7(MAY). doi: 10.3389/fped.2019.00212.

Byng, Danalyn, Johanna I. Lutter, Margarethe E. Wacker, Rudolf A. Jörres, Xiaofei Liu, Stefan Karrasch, Holger Schulz, Claus F. Vogelmeier, and Rolf Holle. 2019. “Determinants of Healthcare Utilization and Costs in COPD Patients: First Longitudinal Results from the German COPD Cohort COSYCONET.” International Journal of Chronic Obstructive Pulmonary Disease Volume 14:1423–39. doi: 10.2147/COPD.S201899.

Häckl, Sebastian, Armin Koch, and Florian Lasch. 2019. “Empirical Evaluation of the Implementation of the EMA Guideline on Missing Data in Confirmatory Clinical Trials: Specification of Mixed Models for Longitudinal Data in Study Protocols.” Pharmaceutical Statistics 18(6):636–44. doi: 10.1002/pst.1964.

Hemmings, Robert, and Armin Koch. 2019. “Commentary on: Subgroup Analysis and Interpretation for Phase 3 Confirmatory Trials: White Paper of the EFSPI/PSI Working Group on Subgroup Analysis by Dane, Spencer, Rosenkranz, Lipkovich, and Parke.” Pharmaceutical Statistics 18(2):140–44. doi: 10.1002/pst.1935.

Heusser, Karsten, Jens Tank, Olaf Holz, Marcus May, Julia Brinkmann, Stefan Engeli, André Diedrich, Theodor Framke, Armin Koch, Anika Großhennig, A. H. Jan Danser, Fred C. G. J. Sweep, Christoph Schindler, Katharina Schwarz, Norbert Krug, Jens Jordan, and Jens M. Hohlfeld. 2019. “Ultrafine Particles and Ozone Perturb Norepinephrine Clearance Rather than Centrally Generated Sympathetic Activity in Humans.” Scientific Reports 9(1):3641. doi: 10.1038/s41598-019-40343-w.

Hinken, Lukas, Hannelore Willenborg, Lukas Aguirre Dávila, and Dorothea Daentzer. 2019. “Outcome Analysis of Molding Helmet Therapy Using a Classification for Differentiation between Plagiocephaly, Brachycephaly and Combination of Both.” Journal of Cranio-Maxillofacial Surgery 47(5):720–25. doi: 10.1016/j.jcms.2019.01.011.

Kendall, Bruce E., Masami Fujiwara, Jasmin Diaz-Lopez, Sandra Schneider, Jakob Voigt, and Sören Wiesner. 2019. “Persistent Problems in the Construction of Matrix Population Models.” Ecological Modelling 406:33–43. doi: 10.1016/j.ecolmodel.2019.03.011.

Lasch, Florian, Kristina Weber, and Armin Koch. 2019. “Commentary: On the Levels of Patient Selection in Registry-Based Randomized Controlled Trials.” Trials 20(1):100. doi: 10.1186/s13063-019-3214-x.

May, Marcus, Theodor Framke, Bernd Junker, Carsten Framme, Amelie Pielen*, and Christoph Schindler*. 2019. “How and Why SGLT2 Inhibitors Should Be Explored as Potential Treatment Option in Diabetic Retinopathy: Clinical Concept and Methodology.” Therapeutic Advances in Endocrinology and Metabolism 10:204201881989188. doi: 10.1177/2042018819891886.

Trudzinski, Franziska C., Mohamad Alqudrah, Albert Omlor, Stephen Zewinger, Danilo Fliser, Timotheus Speer, Frederik Seiler, Frank Biertz, Armin Koch, Claus Vogelmeier, Tobias Welte, Henrik Watz, Benjamin Waschki, Sebastian Fähndrich, Rudolf Jörres, and Robert Bals. 2019. “Consequences of Chronic Kidney Disease in Chronic Obstructive Pulmonary Disease.” Respiratory Research 20(1):151. doi: 10.1186/s12931-019-1107-x.

Wedemeyer, Heiner, Cihan Yurdaydin, Svenja Hardtke, Florin Alexandru Caruntu, Manuela G. Curescu, Kendal Yalcin, Ulus S. Akarca, Selim Gürel, Stefan Zeuzem, Andreas Erhardt, Stefan Lüth, George V. Papatheodoridis, Onur Keskin, Kerstin Port, Monica Radu, Mustafa K. Celen, Ramazan Idilman, Kristina Weber, Judith Stift, Ulrike Wittkop, Benjamin Heidrich, Ingmar Mederacke, Heiko von der Leyen, Hans Peter Dienes, Markus Cornberg, Armin Koch, and Michael P. Manns. 2019. “Peginterferon Alfa-2a plus Tenofovir Disoproxil Fumarate for Hepatitis D (HIDIT-II): A Randomised, Placebo Controlled, Phase 2 Trial.” The Lancet Infectious Diseases 19(3):275–86. doi: 10.1016/S1473-3099(18)30663-7.

  • 2018

Bender, Ralf, Tim Friede, Armin Koch, Oliver Kuss, Peter Schlattmann, Guido Schwarzer, and Guido Skipka. 2018. “Methods for Evidence Synthesis in the Case of Very Few Studies.” Research Synthesis Methods 9(3):382–92. doi: 10.1002/jrsm.1297.

Gutberlet, Marcel, Till F. Kaireit, Andreas Voskrebenzev, Florian Lasch, Julia Freise, Tobias Welte, Frank Wacker, Jens M. Hohlfeld, and Jens Vogel-Claussen. 2018. “Free-Breathing Dynamic 19 F Gas MR Imaging for Mapping of Regional Lung Ventilation in Patients with COPD.” Radiology 286(3):1040–51. doi: 10.1148/radiol.2017170591.

Lingner, Heidrun, Heike Buhr-Schinner, Stefan Hummel, Jochen van der Meyden, Anika Grosshennig, Daniel Nowik, and Konrad Schultz. 2018. “Short-Term Effects of a Multimodal 3-Week Inpatient Pulmonary Rehabilitation Programme for Patients with Sarcoidosis: The ProKaSaRe Study.” Respiration 95(5):343–53. doi: 10.1159/000486964.

Lingner, Heidrun, Lena Blase, Anika Großhennig, and Guido Schmiemann. 2018. “Manual Therapy Applied by General Practitioners for Nonspecific Low Back Pain: Results of the ManRück Pilot-Study.” Chiropractic & Manual Therapies 26(1):39. doi: 10.1186/s12998-018-0202-2.

Weber, Kristina, Florian Lasch, and Armin Koch. 2018. “New Research Strategy with Ambiguous Implications: A Comment on ‘Planning Future Studies Based on the Conditional Power of a Meta-Analysis.’” Statistics in Medicine 37(8):1402–4. doi: 10.1002/sim.7595.

Weber, Kristina, Rob Hemmings, and Armin Koch. 2018. “How to Use Prior Knowledge and Still Give New Data a Chance?” Pharmaceutical Statistics 17(4):329–41. doi: 10.1002/pst.1862.

  • 2017

Hasdemir DB, Aguirre Davila L, Schweitzer N, Meyer BC, Koch A, Vogel A, Wacker F, Rodt T (2017): Evaluation of CT Vascularization Patterns for Survival Prognosis in Patients With Hepatocellular Carcinoma Treated by Conventional TACE. Diagn Interv Radiol 2017; 23: 217-222. DOI: 10.5152/dir.2016.16006

Schweitzer N, Fischer M, Kirstein MM, Berhane S, Kottas M, Sinn M, Gonzalez-Carmona MA, Balta Z, Weismuller TJ, Strassburg CP, Reineke-Plaass T, Bektas H, Manns MP, Johnson P, Weinmann A, Vogel A (2017): Risk estimation for biliary tract cancer: Development and validation of a prognostic store. Liver Int. 2017 Dec;37(12):1852-1860. doi: 10.1111/liv.13517. Epub 2017 Jul 28.

Weber K, Lasch F, Koch A. New research strategy with ambiguous implications: A comment on 'Planning future studies based on the conditional power of a meta-analysis' , Statistics in Medicine, accepted, DOI: 10.1002/sim.7595.

Wacker ME, Kitzing K, Jörres RA, Leidl R, Schulz H, Karrasch S, Karch A, Koch A, Vogelmeier CF, Holle R. The contribution of symptoms and comorbidities to the economic impact of COPD: an analysis of the German COSYCONET cohort.  Int J Chron Obstruct Pulmon Dis. 2017 Dec 4;12:3437-3448. doi: 10.2147/COPD.S141852.

Smid DE, Franssen FME, Gonik M, Miravitlles M, Casanova C, Cosio BG, de Lucas-Ramos P, Marin JM, Martinez C, Mir I, Soriano JB, de Torres JP, Agusti A, Atalay NB, Billington J, Boutou AK, Brighenti-Zogg S, Chaplin E, Coster S, Dodd JW, Dürr S, Fernandez-Villar A, Groenen MTJ, Guimarães M, Hejduk K, Higgins V, Hopkinson NS, Horita N, Houben-Wilke S, Janssen DJA, Jehn M, Joerres R, Karch A, Kelly JL, Kim YI, Kimura H, Koblizek V, Kocks JH, Kon SSC, Kwon N, Ladeira I, Lee SD, Leuppi JD, Locantore N, Lopez-Campos JL, D-C Man W, Maricic L, Mendoza L, Miedinger D, Mihaltan F, Minami S, van der Molen T, Murrells TJ, Nakken N, Nishijima Y, Norman IJ, Novotna B, O'Donnell DE, Ogata Y, Pereira ED, Piercy J, Price D, Pothirat C, Raghavan N, Ringbaek T, Sajkov D, Sigari N, Singh S, Small M, da Silva GF, Tanner RJ, Tsiligianni IG, Tulek B, Tzanakis N, Vanfleteren LEGW, Watz H, Webb KA, Wouters EFM, Xie GG, Yoshikawa M, Spruit MA. Redefining Cut-Points for High Symptom Burden of the Global Initiative for Chronic Obstructive Lung Disease Classification in 18,577 Patients With Chronic Obstructive Pulmonary Disease. J Am Med Dir Assoc. 2017 Dec 1; 18(12):1097.e11-1097.e24. doi: 10.1016/j.jamda.2017.09.003.


  • 2016

Houben-Wilke S, Jörres RA, Bals R, Franssen FM, Gläser S, Holle R, Karch A, Koch A, Magnussen H, Obst A, Schulz H, Spruit MA, Wacker ME, Welte T, Wouters EF, Vogelmeier C, Watz H: Peripheral Artery Disease and its Clinical Relevance in Patients with COPD in the COSYCONET Study. Am J Respir Crit Care Med. 2017 Jan 15;195(2):189-197. doi: 10.1164/rccm.201602-0354OC.

Jakubovski E, Reichert C, Karch A, Buddensiek N, Breuer D, Müller-Vahl K: The ONLINE-TICS Study Protocol: A Randomized Observer-Blind Clinical Trial to Demonstrate the Efficacy and Safety of Internet-Delivered Behavioral Treatment for Adults with Chronic Tic Disorders. Front Psychiatry; 7:119. doi: 10.3389/fpsyt.2016.00119.

Wacker ME, Jörres RA, Karch A, Koch A, Heinrich J, Karrasch S, Schulz H, Peters A, Gläser S, Ewert R, Baumeister SE, Vogelmeier C, Leidl R, Holle R; COSYCONET study group: Relative impact of COPD and comorbidities on generic health-related quality of life: a pooled analysis of the COSYCONET patient cohort and control subjects from the KORA and SHIP studies. Respir Res.; 17(1):81. doi: 10.1186/s12931-016-0401-0.

Karch A, Koch A, Grünwald V: A phase II trial comparing pazopanib with doxorubicin as first-line treatment in elderly patients with metastatic or advanced soft tissue sarcoma (EPAZ): study protocol for a randomized controlled trial. Trials; 17(1):312. doi: 10.1186/s13063-016-1434-x.

Chatzikyrkou C, Eichler J, Karch A, Clajus C, Scurt FG, Ramackers W, Lehner F, Menne J, Haller H, Mertens PR, Schiffer M: Short- and long-term effects of the use of RAAS blockers immediately after renal transplantation. Blood Press. 2016 May 19:1-9. [Epub ahead of print]

Wacker ME, Jörres RA, Karch A, Wilke S, Heinrich J, Karrasch S, Koch A, Schulz H, Watz H, Leidl R, Vogelmeier C, Holle R; COSYCONET-Consortium: Assessing health-related quality of life in COPD: comparing generic and disease-specific instruments with focus on comorbidities. BMC Pulm Med.; 16(1):70. doi: 10.1186/s12890-016-0238-9.

Karch A, Koch A, Zapf A, Zerr I, Karch A: Partial verification bias and incorporation bias affected accuracy estimates of diagnostic studies for biomarkers that were part of an existing composite gold standard. J Clin Epidemiol. 78:73-82. doi: 10.1016/j.jclinepi.2016.03.022.

Scheper V, Leifholz M, von der Leyen H, Keller M, Denkena U, Koch A, Karch A, Miller J, Lenarz T. ACEMg-mediated hearing preservation in cochlear implant patients receiving different electrode lengths (PROHEARING): study protocol for a randomized controlled trial. Trials. 2016; 17:394. DOI 10.1186/s13063-016-1526-7.

Karch A, Vogelmeier C, Welte T, Bals R, Kauczor HU, Biederer J, Heinrich J, Schulz H, Gläser S, Holle R, Watz H, Korn S, Adaskina N, Biertz F, Vogel C, Vestbo J, Wouters EFM, Rabe KF, Söhler S, Koch A, Jörres RA, for the COSYCONET Study Group. The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline. Respir.Med. 2016; 112(18-24). DOI 10.1016/j.rmed.2016.03.008

Hueper K, Khalifa AA, Bräsen JH, Vo Chieu VD, Gutberlet M, Wintterle S, Lehner F, Richter N, Peperhove M, Tewes S, Weber K, Haller H, Wacker F, Gwinner W, Gueler F, Hartung D. Diffusion-Weighted imaging and diffusion tensor imaging detect delayed graft function and correlate with allograft fibrosis in patients early after kidney transplantation. J.Magn.Reson.Imaging 2016; 44(1):112-121. DOI 10.1002/jmri.25158

Kammer J, Ziesing S, Aguirre Davila L, Bültmann E, Illsinger S, Das AM, Haffner D, Hartmann H. Neurological Manifestations of Mycoplasma pneumoniae Infection in Hospitalized Children and Their Long-Term Follow-Up. Neuropediatrics 2016; 47(5):308-317. DOI 10.1055/s-0036-1584325

Höhn M, von Jan U, Framke T, Albrecht UV. Classification of Health Related Applications. Stud.Health Technol.Inform. 2016; 226:139-142. DOI 10.3233/978-1-61499-664-4-139

Lenzen H, Musmann E, Kottas M, Schönemeier B, Köhnlein T, Manns MP, Lankisch TO. Acute gastrointestinal bleeding cases presenting to the emergency department are associated with age, sex and seasonal and circadian factors. Eur.J.Gastroenterol.Hepatol. 2017; 29(1):78-83. DOI 10.1097/MEG.0000000000000752

Leo F, Bartels S, Mägel L, Framke T, Büsche G, Jonigk D, Christgen M, Lehmann U, Kreipe H. Prognostic factors in the myoepithelial-like spindle cell type of metaplastic breast cancer. Virchows Arch. 2016; 469(2):191-201. DOI 10.1007/s00428-016-1950-9

Lueer K, Biller H, Casper A, Windt H, Mueller M, Badorrek P, Haefner D, Framke T, Koch A, Ziehr H, Krug N, Koch W, Hohlfeld JM. Safety, efficacy and repeatability of a novel house dust mite allergen challenge technique in the Fraunhofer allergen challenge chamber. Allergy 2016; 71(12):1693-1700. DOI 10.1111/all.12947

Paparoupa M, Spineli L, Framke T, Ho H, Schuppert F, Gillissen A. Pulmonary Embolism in Pneumonia: Still a Diagnostic Challenge? Results of a Case-Control Study in 100 Patients. Dis.Markers 2016; DOI 10.1155/2016/8682506

Rios N, Adaskina N, Frömke C, Papendorf F, Schippert C, Koch A, Hillemanns P, Park-Simon TW. The Benefit of Baseline Staging-Risk Assessment of Distant Breast Cancer Metastases by Tumor Stage.
Anticancer Res. 2016; 36(9):4909-4914

Derlin T, Thiele J, Weiberg D, Thackeray JT, Püschel K, Wester HJ, Aguirre Davila L, Larena-Avellaneda A, Daum G, Bengel FM, Schumacher U. Evaluation of 68Ga-Glutamate Carboxypeptidase II Ligand Positron Emission Tomography for Clinical Molecular Imaging of Atherosclerotic Plaque Neovascularization Arterioscler. Thromb.Vasc.Biol. 2016; 36(11):2213-2219. DOI 10.1161/ATVBAHA.116.307701

Klapdor R, Hillemanns P, Wölber L, Jückstock J, Hilpert F, de Gregorio N, Iborra S, Sehouli J, Habermann A, Fürst ST, Strauss HG, Baumann K, Thiel F, Mustea A, Meier W, Harter P, Wimberger P, Hanker L, Schmalfeldt B, Canzler U, Fehm T, Luyten A, Hellriegel M, Kosse J, Heiss C, Hantschmann P, Mallmann P, Tanner B, Pfisterer J, Richter B, Jäger M, Mahner S. Outcome After Sentinel Lymph Node Dissection in Vulvar Cancer: A Subgroup Analysis of the AGO-CaRE-1 Study. Ann.Surg.Oncol. 2016; DOI: 10.1245/s10434-016-5687-0

Lucke T, Herrera R, Wacker M, Holle R, Biertz F, Nowak D, Huber RM, Söhler S, Vogelmeier C, Ficker JH, Muckter H, Jörres RA, COSYCONET-Consortium. Systematic Analysis of Self-Reported Comorbidities in Large Cohort Studies - A Novel Stepwise Approach by Evaluation of Medication. PLoS One 2016; 11(10) DOI 10.1371/journal.pone.0163408

Bormann KH, Weber K, Kloppenburg H, Koch A, Meiser P, Gellrich NC. Perioperative Bromelain Therapy after Wisdom Teeth Extraction - A Randomized, Placebo-Controlled, Double-Blinded, Three-Armed, Cross-Over Dose-Finding Study. Phytother.Res. 2016; 30(12):2012-2019. DOI 10.1002/ptr.5707

Könneker S, Broelsch GF, Kuhbier JW, Framke T, Neubert N, Dastagir K, Mett T, Vogt PM, Jokuszies A. Outcome Analysis of End-to-End and End-to-Side Anastomoses in 131 Patients Undergoing Microsurgical Free Flap Reconstruction of the Lower Extremity. J Reconstr Microsurg Open 2016. DOI: 10.1055/s-0036-1593815

Neubert N, Vogt PM, May M, Boyce M, Koenneker S, Budde E, Jokuszies A. Does an Early and Aggressive Combined Wrapping and Dangling Procedure Affect the Clinical Outcome of Lower Extremity Free Flaps?-A Randomized Controlled Prospective Study Using Microdialysis Monitoring. J.Reconstr.Microsurg. 2016; 32(4):262-270. DOI 10.1055/s-0035-1568882

Deterding K, Spinner CD, Schott E, Welzel TM, Gerken G, Klinker H, Spengler U, Wiegand J, Zur Wiesch JS, Pathil A, Cornberg M, Umgelter A, Zöllner C, Zeuzem S, Papkalla A, Weber K, Hardtke S, von der Leyen H, Koch A, von Witzendorff D, Manns MP, Wedemeyer H, HepNet Acute HCV IV Study Group. Ledipasvir plus sofosbuvir fixed-dose combination for 6 weeks in patients with acute hepatitis C virus genotype 1 monoinfection (HepNet Acute HCV IV): an open-label, single-arm, phase 2 study. Lancet Infect.Dis. 2016. DOI:10.1016/S1473-3099(16)30408-X

Wranke A, Serrano BC, Heidrich B, Kirschner J, Bremer B, Lehmann P, Hardtke S, Deterding K, Port K, Westphal M, Manns MP, Cornberg M, Wedemeyer H. Antiviral treatment and liver-related complications in hepatitis delta Hepatology 2016. DOI:10.1002/hep.28876


  • 2015

  • 2014

  • 2013

  • 2012

  • 2011