Publications - Dr. Johannes Greve
Marquardt A, Münchhoff MS, Krohn J, Palarz PM, Taft MH, Greve JN, Di Donato N, Buettner FFR, Manstein DJ.
Disruption of SETD3-mediated histidine-73 methylation by the BWCFF-associated β-actin G74S mutation. FEBS Letters, 2025. https://doi.org/10.1002/1873-3468.70088
Heiringhoff RS, Marke D, Curth U, Greve JN*.
The SH3BGRL protein family nucleates and caps actin filaments via its conserved thioredoxin fold. bioRxiv, 2025. https://doi.org/10.1101/2025.03.25.645244
*corresponding author
Greve JN*, Manstein DJ*.
Molecular mechanisms of hotspot variants in cytoskeletal β-actin associated with Baraitser-Winter syndrome. FEBS Journal, 2025. https://doi.org/10.1111/febs.70018
*co-corresponding author
Düsterhöft S, Greve JN, Garbers C.
Investigating plasticity within the interleukin-6 family with AlphaFold-Multimer. Computational and Structural Biotechnology Journal, 2025. doi.org/10.1016/j.csbj.2025.02.030
Di Donato N, NMA Consortium, Thom A, Rump A, Greve JN, Kropp M, Cadiñanos J, Calabro S, Cathey S, Chung B, Cope H, Costales M, Cuvertino S, Dinkel P, Erripi K, Fry AE, Garavelli L, Guan K, Hoffjan S, Janzarik WG, Koenig M, Kreimer I, Kuenzel K, Mancini G, Marin-Reina P, Meinhardt A, Niehaus I, Pilz D, Ricca I, Simarro FS, Schrock E, Marquardt A, Taft MH, Tezcan K, Thunström S, Verhagen J, Verloes A, Wollnik B, Krawitz P, Hsieh T-C, Zeef L, Seifert M, Heide M, Lawrence CB, Roberts N, Manstein DJ, Woolf AS, Banka S
Genomic and biological panoramas of non-muscle actinopathies. Preprint Medarxiv, 2024.
Hecquet T, Arbogast N, Suhner D, Goetz A, Amann G, Yürekli S, Marangoni F, Greve JN, Di Donato N, Reymann AC
Classification of human actin pathological variants using C. elegans CRISPR-generated models. Preprint Bioarxiv, 2024.
https://doi.org/10.1101/2024.07.22.604239
Greve JN*, Manstein DJ*
Baraitser-Winter Syndrome Hotspot Mutation R196H in Cytoskeletal β-actin Reduces F-actin Stability and Perturbs Interaction with the Arp2/3 Complex. Preprint Bioarxiv, 2024. doi.org/10.1101/2024.03.20.585892
*co-corresponding authors
Kengyel A*, Palarz PM*, Krohn J, Marquardt A, Greve JN, Heiringhoff R, Jörns A, Manstein DJ.
Motor Properties of Myosin 5C Are Modulated by Tropomyosin Isoforms and Inhibited by Pentabromopseudilin. Frontiers in Physiology, 2024. doi.org/10.3389/fphys.2024.1394040
*contributed equally
Greve JN,* Schwäbe FV*, Taft MH, Manstein DJ.
Biochemical Characterization of cardiac α-actin Mutations A21V and D26N Implicated in Hypertrophic Cardiomyopathy. Cytoskeleton, 2024.
*contributed equally
Greve JN, Marquardt A, Heiringhoff R, Reindl T, Thiel C, Di Donato N, Taft MH, Manstein DJ. The non–muscle actinopathy–associated mutation E334Q in cytoskeletal γ–actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins. eLife, 2023. doi.org/10.7554/eLife.93013.1
Reindl T*, Giese S*, Greve JN, Reinke PY, Chizhov I, Latham SL, Mulvihill DP, Taft MH, Manstein DJ.
Distinct actin-tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes. iScience, 2022. doi.org/10.1016/j.isci.2022.104484
*contributed equally
Greve JN, Schwäbe FV, Pokrant T, Faix J, Di Donato N, Taft MH, Manstein DJ.
Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB-associated syndromic thrombocytopenia by impairing actin dynamics. European Journal of Cell Biology, 2022. doi.org/10.1016/j.ejcb.2022.151216
Pertici I*, Taft MH*, Greve JN, Fedorov R, Caremani M, Manstein DJ.
Allosteric modulation of cardiac myosin mechanics and kinetics by the conjugated omega-7,9 trans-fat rumenic acid. Journal of Physiology, 2021. doi.org/10.1113/JP281563
*contributed equally