Current Projects

• Biochemical analysis of SMN function in actin cytoskeleton regulation
• Structural characterization of the SMN protein by cryo electron microscopy
• Cellular consequences of SMN deficiency in different cell types
• Purification and kinetic characterization of recombinant human Myosin-9a and Myosin-9b
• Investigations on the molecular mechanism underlying specific myosin inhibition by small-molecule compounds