Veröffentlichungen 2016

Abbas M, Steffens S, Bellut M, Becker JU, Großhennig A, Eggers H, Wegener G, Kuczyk MA, Kreipe HH, Grünwald V, Schrader AJ, Ivanyi P:

Do programmed death 1 (PD-1) and its ligand (PD-L1) play a role in patients with non-clear cell renal cell carcinoma?

Med Oncol 2016; 33(6): 59

Abbas M, Steffens S, Bellut M, Eggers H, Großhennig A, Becker JU, Wegener G, Schrader AJ, Grünwald V, Ivanyi P:

Intratumoral expression of programmed death ligand 1 (PD-L1) in patients with clear cell renal cell carcinoma (ccRCC).

Med Oncol 2016; 33(7): 80

Abuharbid G, Esmaeilzadeh M, Hartmann C, Hermann EJ, Krauss JK:

Multiple desmoplastic infantile gliomas-therapeutic challenges.

Childs Nerv Syst 2016; 32(1): 17

Alfonso JC, Köhn-Luque A, Stylianopoulos T, Feuerhake F, Deutsch A, Hatzikirou H:

Why one-size-fits-all vaso-modulatory interventions fail to control glioma invasion: in silico insights.

Sci Rep 2016; 6: 37283

Alfonso JC, Schaadt NS, Schönmeyer R, Brieu N, Forestier G, Wemmert C, Feuerhake F, Hatzikirou H:

In-silico insights on the prognostic potential of immune cell infiltration patterns in the breast lobular epithelium.

Sci Rep 2016; 6: 33322

Apou G, Schaadt NS, Naegel B, Forestier G, Schönmeyer R, Feuerhake F, Wemmert C, Grote A:

Detection of lobular structures in normal breast tissue.

Comput Biol Med 2016; 74: 91-102

Avsar M, Jansson K, Sommer W, Kruse B, Thissen S, Dreckmann K, Knoefel AK, Salman J, Hafer C, Hecker J, Buechler G, Karstens JH, Jonigk D, Länger F, Kaever V, Falk CS, Hewicker-Trautwein M, Ungefroren H, Haverich A, Strüber M, Warnecke G:

Augmentation of Transient Donor Cell Chimerism and Alloantigen-Specific Regulation of Lung Transplants in Miniature Swine.

Am J Transplant 2016; 16(5): 1371-1382

Baretton G, Dietel M, Gaiser T, Kirchner T, Kreipe HH, Quaas A, Röcken C, Rüschoff J, Tannapfel A, Lordick F, Al-Batran S, Hofheinz R, Lorenzen S, Moehler M, Thuss-Patience P:

[HER2 testing in gastric cancer : Results of a meeting of German experts].

Pathologe 2016; 37(4): 361-366

Bartels S, Lehmann U, Büsche G, Schlue J, Kreipe H:

Evolution of chronic myelomonocytic leukemia to myeloproliferative neoplasm.

Ann Hematol 2016; 95(8): 1377-1380

Bartels S, Schipper E, Hasemeier B, Kreipe H, Lehmann U:

Routine clinical mutation profiling using next generation sequencing and a customized gene panel improves diagnostic precision in myeloid neoplasms.

Oncotarget 2016; 7(21):30084-30093

Baumann AK, Schlue J, Noyan F, Hardtke-Wolenski M, Lehner F, Barg-Hock H, Klempnauer J, Manns MP, Taubert R, Jaeckel E:

Preferential accumulation of T helper cells but not cytotoxic T cells characterizes benign subclinical rejection of human liver allografts.

Liver Transpl 2016: 22(7): 943-955

Baumert BG, Hegi ME, van den Bent MJ, von Deimling A, Gorlia T, Hoang-Xuan K, Brandes AA, Kantor G, Taphoorn MJ, Hassel MB, Hartmann C, Ryan G, Capper D, Kros JM, Kurscheid S, Wick W, Enting R, Reni M, Thiessen B, Dhermain F, Bromberg JE, Feuvret L, Reijneveld JC, Chinot O, Gijtenbeek JM, Rossiter JP, Dif N, Balana C, Bravo-Marques J, Clement PM, Marosi C, Tzuk-Shina T, Nordal RA, Rees J, Lacombe D, Mason WP, Stupp R:

Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study.

Lancet Oncol 2016; 17(11): 1521-1532

Behler-Janbeck F, Takano T, Maus R, Stolper J, Jonigk D, Tort Tarrés M, Fuehner T, Prasse A, Welte T, Timmer MS, Stocker BL, Nakanishi Y, Miyamoto T, Yamasaki S, Maus UA:

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia.

PLoS Pathog 2016; 12(12): e1006038

Behling F, Barrantes-Freer A, Skardelly M, Nieser M, Christians A, Stockhammer F, Rohde V, Tatagiba M, Hartmann C, Stadelmann C, Schittenhelm J:

Frequency of BRAF V600E mutations in 969 central nervous system neoplasms.

Diagn Pathol 2016; 11(1): 55

Beier R, Sykora KW, Woessmann W, Maecker-Kolhoff B, Sauer M, Kreipe HH, Dörk-Bousset T, Kratz C, Lauten M:

Allogeneic-matched sibling stem cell transplantation in a 13-year-old boy with ataxia telangiectasia and EBV-positive non-Hodgkin lymphoma.

Bone Marrow Transplant 2016; 51(9): 1271-1274

Borlak J, Länger F, Spanel R, Schöndorfer G, Dittrich C:

Immune-mediated liver injury of the cancer therapeutic antibody catumaxomab targeting EpCAM, CD3 and Fcγ receptors.

Oncotarget 2016; 7(19): 28059-28074

Buesche G, Teoman H, Giagounidis A, Göhring G, Schlegelberger B, Ganser A, Aul C, Kreipe HH:

Impaired formation of erythroblastic islands is associated with erythroid failure and poor prognosis in a significant proportion of patients with myelodysplastic syndromes.

Haematologica 2016; 101(5): e177-181

Bures M, Höffler HK, Friedel G, Kyriss T, Boedeker E, Länger F, Zardo P, Zhang R:

Albumin-glutaraldehyde glue for repair of superficial lung defect: an in vitro experiment.

J Cardiothorac Surg 2016; 11(1): 63

Bures M, Zardo P, Länger F, Zhang R:

Improved application technique of albumin-glutaraldehyde glue for repair of superficial lung defects.

J Cardiothorac Surg 2016; 11(1): 149

Chapuy B, Roemer MG, Stewart C, Tan Y, Abo RP, Zhang L, Dunford AJ, Meredith DM, Thorner AR, Jordanova ES, Liu G, Feuerhake F, Ducar MD, Illerhaus G, Gusenleitner D, Linden EA, Sun HH, Homer H, Aono M, Pinkus GS, Ligon AH, Ligon KL, Ferry JA, Freeman GJ, van Hummelen P, Golub TR, Getz G, Rodig SJ, de Jong D, Monti S, Shipp MA.

Targetable genetic features of primary testicular and primary central nervous system lymphomas.

Blood 2016; 127(7): 869-881

Christgen M, Länger F, Kreipe H:

[Histological grading of breast cancer].

Pathologe 2016; 37(4): 328-336

Christgen M, Steinemann D, Kühnle E, Länger F, Gluz O, Harbeck N, Kreipe H:

Lobular breast cancer: Clinical, molecular and morphological characteristics.

Pathol Res Pract 2016; 212(7): 583-597 [Review]

Christgen M, van Luttikhuizen JL, Raap M, Braubach P, Schmidt L, Jonigk D, Feuerhake F, Lehmann U, Schlegelberger B, Kreipe HH, Steinemann D:

Precise ERBB2 copy number assessment in breast cancer by means of molecular inversion probe array analysis.

Oncotarget. 2016 Oct 3. doi: 10.18632/oncotarget.12421. [Epub ahead of print]

Dabral S, Tian X, Kojonazarov B, Savai R, Ghofrani HA, Weissmann N, Florio M, Sun J, Jonigk D, Maegel L, Grimminger F, Seeger W, Savai Pullamsetti S, Schermuly RT:

Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension.

Eur Respir J 2016; 48(4): 1137-1149

Demtröder C, Solass W, Zieren J, Strumberg D, Giger-Pabst U, Reymond MA:

Pressurized intraperitoneal aerosol chemotherapy with oxaliplatin in colorectal peritoneal metastasis.

Colorectal Dis 2016; 18(4): 364-371

Denkert C, Wienert S, Poterie A, Loibl S, Budczies J, Badve S, Bago-Horvath Z, Bane A, Bedri S, Brock J, Chmielik E, Christgen M, Colpaert C, Demaria S, Van den Eynden G, Floris G, Fox SB, Gao D, Ingold Heppner B, Kim SR, Kos Z, Kreipe HH, Lakhani SR, Penault-Llorca F, Pruneri G, Radosevic-Robin N, Rimm DL, Schnitt SJ, Sinn BV, Sinn P, Sirtaine N, O'Toole SA, Viale G, Van de Vijver K, de Wind R, von Minckwitz G, Klauschen F, Untch M, Fasching PA, Reimer T, Willard-Gallo K, Michiels S, Loi S, Salgado R:

Standardized evaluation of tumor-infiltrating lymphocytes in breast cancer: results of the ring studies of the international immuno-oncology biomarker working group.

Mod Pathol 2016; 29(10): 1155-1164

Derlin T, Alchalby H, Bannas P, Laqmani A, Ayuk F, Triviai I, Kreipe HH, Bengel FM, Kröger N:

Serial 18F-fluorodeoxyglucose positron emission tomography for monitoring treatment response after allogeneic stem cell transplantation for myelofibrosis.

J Nucl Med 2016; 57(10): 1556-1559

Derlin T, Jonigk D, Bauersachs J, Bengel FM:

Molecular Imaging of Chemokine Receptor CXCR4 in Non-Small Cell Lung Cancer Using 68Ga-Pentixafor PET/CT: Comparison With 18F-FDG.

Clin Nucl Med 2016; 41(4):e204-205

Derlin T, Kreipe HH, Schumacher U, Soudah B:

PSMA Expression in Tumor Neovasculature Endothelial Cells of Follicular Thyroid Adenoma as Identified by Molecular Imaging Using 68Ga-PSMA Ligand PET/CT.

Clin Nucl Med. 2016 Dec 16. doi: 10.1097/RLU.0000000000001487. [Epub ahead of print]

Dietmaier W, Merkelbach-Bruse S, Jung A, Lehmann U:

[Report on sessions and the general meeting of the working group Molecular Pathology].

Pathologe 2016; 37(Suppl 2): 249-252

Dogan A, Solass W, Tempfer CB:

Cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy for recurrent adult granulosa cell tumor: A case report.

Gynecol Oncol Rep 2016; 16: 21-23

Endris V, Stenzinger A, Pfarr N, Penzel R, Möbs M, Lenze D, Darb-Esfahani S, Hummel M, Sabine-Merkelbach-Bruse, Jung A, Lehmann U, Kreipe H, Kirchner T, Büttner R, Jochum W, Höfler G, Dietel M, Weichert W, Schirmacher P:

NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial.

Virchows Arch 2016; 468(6): 697-705

Feist H, von Kaisenberg C, Hussein K:

[Pathoanatomical and clinical aspects of the placenta in preterm birth].

Pathologe. 2016 Jun 2. [Epub ahead of print] German.

Gluz O, Liedtke C, Huober J, Peyro-Saint-Paul H, Kates RE, Kreipe HH, Hartmann A, Pelz E, Erber R, Mohrmann S, Möbus V, Augustin D, Hoffmann G, Thomssen C, Jänicke F, Kiechle M, Wallwiener D, Kuhn W, Nitz U, Harbeck N; EC-Doc investigators (West German Study Group/AGO-B):

Comparison of prognostic and predictive impact of genomic or central grade and immunohistochemical subtypes or IHC4 in HR+/HER2- early breast cancer: WSG-AGO EC-Doc Trial.

Ann Oncol 2016; 27(6): 1035-1040

Gluz O, Nitz UA, Christgen M, Kates RE, Shak S, Clemens M, Kraemer S, Aktas B, Kuemmel S, Reimer T, Kusche M, Heyl V, Lorenz-Salehi F, Just M, Hofmann D, Degenhardt T, Liedtke C, Svedman C, Wuerstlein R, Kreipe HH, Harbeck N:

West German Study Group Phase III PlanB Trial: First Prospective Outcome Data for the 21-Gene Recurrence Score Assay and Concordance of Prognostic Markers by Central and Local Pathology Assessment.

J Clin Oncol 2016; 34(20): 2341-2349

Gratwohl A, Pfirrmann M, Zander A, Kröger N, Beelen D, Novotny J, Nerl C, Scheid C, Spiekermann K, Mayer J, Sayer HG, Falge C, Bunjes D, Döhner H, Ganser A, Schmidt-Wolf I, Schwerdtfeger R, Baurmann H, Kuse R, Schmitz N, Wehmeier A, Th Fischer J, Ho AD, Wilhelm M, Goebeler ME, Lindemann HW, Bormann M, Hertenstein B, Schlimok G, Baerlocher GM, Aul C, Pfreundschuh M, Fabian M, Staib P, Edinger M, Schatz M, Fauser A, Arnold R, Kindler T, Wulf G, Rosselet A, Hellmann A, Schäfer E, Prümmer O, Schenk M, Hasford J, Heimpel H, Hossfeld DK, Kolb HJ, Büsche G, Haferlach C, Schnittger S, Müller MC, Reiter A, Berger U, Saußele S, Hochhaus A, Hehlmann R:

Long-term outcome of patients with newly diagnosed chronic myeloid leukemia: a randomized comparison of stem cell transplantation with drug treatment.

Leukemia 2016; 30(3): 562-569

Gren ST, Janciauskiene S, Sandeep S, Jonigk D, Kvist PH, Gerwien JG, Håkansson K, Grip O:

The protease inhibitor cystatin C down-regulates the release of IL-β and TNF-α in lipopolysaccharide activated monocytes.

J Leukoc Biol 2016; 100(4): 811-822

Groepper S, Schlue J, Haferlach C, Giagounidis A:

Transfusion Independency and Histological Remission in a Patient with Advanced Primary Myelofibrosis Receiving Iron-Chelation Therapy with Deferasirox.

Oncol Res Treat 2016; 39(6): 384-387

Grünwald V, Länger F, Raatschen HJ, Beilken A:

Proof of principle for bevacizumab activity in desmoid-type fibromatosis.

Clin Sarcoma Res 2016; 6: 5

Hardtke-Wolenski M, Dywicki J, Fischer K, Hapke M, Sievers M, Schlue J, Anderson MS, Taubert R, Noyan F, Manns MP, Jäckel E:

The influence of genetic predisposition and autoimmune hepatitis inducing antigens in disease development.

J Autoimmun. 2016 Dec 11. pii: S0896-8411(16)30364-X. doi: 10.1016/j.jaut.2016.12.001. [Epub ahead of print]

Hering T, Braubach P, Landwehrmeyer GB, Lindenberg KS, Melzer W:

Fast-to-Slow Transition of Skeletal Muscle Contractile Function and Corresponding Changes in Myosin Heavy and Light Chain Formation in the R6/2 Mouse Model of Huntington's Disease.

PLoS One 2016; 11(11): e0166106

Höckendorf U, Yabal M, Herold T, Munkhbaatar E, Rott S, Jilg S, Kauschinger J, Magnani G, Reisinger F, Heuser M, Kreipe H, Sotlar K, Engleitner T, Rad R, Weichert W, Peschel C, Ruland J, Heikenwalder M, Spiekermann K, Slotta-Huspenina J, Groß O, Jost PJ:

RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.

Cancer Cell 2016; 30(1): 75-91

Huang K, Yang M, Pan Z, Heidel FH, Scherr M, Eder M, Fischer T, Büsche G, Welte K, von Neuhoff N, Ganser A, Li Z:

Leukemogenic potency of the novel FLT3-N676K mutant.

Ann Hematol 2016; 95(5): 783-791

Hueper K, Gutberlet M, Bräsen JH, Jang MS, Thorenz A, Chen R, Hertel B, Barrmeyer A, Schmidbauer M, Meier M, von Vietinghoff S, Khalifa A, Hartung D, Haller H, Wacker F, Rong S, Gueler F:

Multiparametric Functional MRI: Non-Invasive Imaging of Inflammation and Edema Formation after Kidney Transplantation in Mice.

PLoS One 2016; 11(9): e0162705

Hueper K, Khalifa AA, Bräsen JH, Vo Chieu VD, Gutberlet M, Wintterle S, Lehner F, Richter N, Peperhove M, Tewes S, Weber K, Haller H, Wacker F, Gwinner W, Gueler F, Hartung D:

Diffusion-Weighted imaging and diffusion tensor imaging detect delayed graft function and correlate with allograft fibrosis in patients early after kidney transplantation.

J Magn Reson Imaging 2016; 44(1): 112-121

Hussein K, Peter C, Sedlacek L, Kaisenberg CV, Kreipe HH:

[Necrotizing funisitis : Histopathological indicator of occult congenital syphilis].

Pathologe. 2016 Jul 13. [Epub ahead of print] German.

Hussein K, Stucki-Koch A, Alchalby H, Triviai I, Kröger N, Kreipe H:

Cytokine Expression Pattern in Bone Marrow Microenvironment after Allogeneic Stem Cell Transplantation in Primary Myelofibrosis.

Biol Blood Marrow Transplant 2016; 22(4): 644-650

Izykowski N, Kuehnel M, Hussein K, Mitschke K, Gunn M, Janciauskiene S, Haverich A, Warnecke G, Laenger F, Maus U, Jonigk D:

Organizing pneumonia in mice and men.

J Transl Med 2016; 14(1): 169

Junge N, Tiedau M, Verboom M, Hallensleben M, Blasczyk R, Schlue J, Goldschmidt I, Pfister ED, Baumann U:

Human leucocyte antigens and pediatric autoimmune liver disease: diagnosis and prognosis.

Eur J Pediatr 2016; 175(4): 527-537

Kakchekeeva T, Demtröder C, Herath NI, Griffiths D, Torkington J, Solaß W, Dutreix M, Reymond MA:

In Vivo Feasibility of Electrostatic Precipitation as an Adjunct to Pressurized Intraperitoneal Aerosol Chemotherapy (ePIPAC).

Ann Surg Oncol 2016; 23(Suppl 5): 592-598

Kampers J, Orjuela-Grimm M, Schober T, Schulz TF, Stiefel M, Klein C, Körholz D, Mauz-Körholz C, Kreipe H, Beier R, Maecker-Kolhoff B:

Classical Hodgkin lymphoma-type PTLD after solid organ transplantation in children: a report on 17 patients treated according to subsequent GPOH-HD treatment schedules.

Leuk Lymphoma 2016; 11: 1-6

Kellner M, Heidrich M, Lorbeer RA, Antonopoulos GC, Knudsen L, Wrede C, Izykowski N, Grothausmann R, Jonigk D, Ochs M, Ripken T, Kühnel MP, Meyer H:

A combined method for correlative 3D imaging of biological samples from macro to nano scale.

Sci Rep 2016; 6: 35606

Khalili-Harbi N, Herath N, Solass W, Giger-Pabst U, Dutreix M, Reymond MA:

Pressurized intraluminal aerosol chemotherapy with Dbait in the distal esophagus of swine.

Endoscopy 2016; 48(2): 184-187

Kielgast F, Schmidt H, Braubach P, Winkelmann VE, Thompson KE, Frick M, Dietl P, Wittekindt OH:

Glucocorticoids Regulate Tight Junction Permeability of Lung Epithelia by Modulating Claudin 8.

Am J Respir Cell Mol Biol 2016; 54(5): 707-717

Koestner W, Dämmrich M, Derlin T:

Inzidenteller tenosynovialer Riesenzelltumor des Musculus flexor hallucis longus: seltene Differenzialdiagnose stoffwechselaktiver Läsionen in der F-18-FDG PET/CT.

Rofo 2016; 188(3): 300-301 [Case Report]

Koinzer S, Bauer M, Garbrecht N, Bräsen JH, Roider J:

Differenzialdiagnose eines deletären Papillentumors : Eine Herausforderung für den Ophthalmopathologen.

Ophthalmologe 2016; 113(1): 75-77 [German]

Korstanje R, Deutsch K, Bolanos-Palmieri P, Hanke N, Schroder P, Staggs L, Bräsen JH, Roberts IS, Sheehan S, Savage H, Haller H, Schiffer M:

Loss of Kynurenine 3-Mono-oxygenase Causes Proteinuria.

J Am Soc Nephrol 2016; 27(11): 3271-3277

Kosfeld A, Kreuzer M, Daniel C, Brand F, Schäfer AK, Chadt A, Weiss AC, Riehmer V, Jeanpierre C, Klintschar M, Bräsen JH, Amann K, Pape L, Kispert A, Al-Hasani H, Haffner D, Weber RG:

Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT).

Hum Genet 2016; 135(1): 69-87

Krüger M, Zinne N, Shin H, Zhang R, Biancosino C, Kropivnitskaja I, Länger F, Haverich A, Dettmer S:

[Minimally invasive chest surgery : Is palpation control still necessary with modern computed tomography?].

Chirurg 2016; 87(2): 136-143 [German]

Krüger M, Zinne N, Shin H, Zhang R, Biancosino C, Kropivnitskaja I, Länger F, Haverich A, Dettmer S:

[Minimally invasive chest surgery. Is palpation control still necessary with modern computed tomography?].

Chirurg 2016; 87(2): 136-143

Kuehnel M, Maegel L, Vogel-Claussen J, Robertus JL, Jonigk D:

Airway remodelling in the transplanted lung.

Cell Tissue Res. 2016 Nov 12. [Epub ahead of print] Review.

Kvasnicka HM, Beham-Schmid C, Bob R, Dirnhofer S, Hussein K, Kreipe H, Kremer M, Schmitt-Graeff A, Schwarz S, Thiele J, Werner M, Stein H:

Problems and pitfalls in grading of bone marrow fibrosis, collagen deposition and osteosclerosis - a consensus-based study.

Histopathology 2016; 68(6): 905-915

Lemound J, Schenk M, Keller G, Stucki-Koch A, Witting S, Kreipe H, Hussein K:

Cytogenetic and immunohistochemical biomarker profiling of therapy-relevant factors in salivary gland carcinomas.

J Oral Pathol Med 2016; 45(9): 655-663

Leo F, Bartels S, Mägel L, Framke T, Büsche G, Jonigk D, Christgen M, Lehmann U, Kreipe H:

Prognostic factors in the myoepithelial-like spindle cell type of metaplastic breast cancer.

Virchows Arch 2016; 469(2): 191-201

Loeschke S, Ohlmann AK, Bräsen JH, Holst R, Warnke PH:

Prognostic value of HMGA2, P16, and HPV in oral squamous cell carcinomas.

J Craniomaxillofac Surg 2016; 44(9): 1422-9

Lordick F, Al-Batran SE, Hofheinz RD, Lorenzen S, Thuss-Patience P, Baretton GB, Dietel M, Gaiser T, Kirchner T, Kreipe HH, Quaas A, Röcken C, Rüschoff J, Tannapfel A:

[HER2 testing in gastric cancer - results of a German expert meeting].

Z Gastroenterol 2016; 54(8): 791-796

Loosen SH, Schmeding M, Roderburg C, Binnebösel M, Temizel I, Mottaghy FM, Tischendorf JJ, Tacke F, Gaisa NT, Hussein K, Lehmann U, Trautwein C, Neumann UP, Luedde T:

A liver nodule in a patient transplanted for primary sclerosing cholangitis: an interdisciplinary diagnostic approach.

Z Gastroenterol. 2016 Oct 5. [Epub ahead of print]

Lüdemann W, Banan R, Hartmann C, Bertalanffy H, Di Rocco C:

Pediatric intracranial primary anaplastic ganglioglioma.

Childs Nerv Syst. 2016 Dec 5. [Epub ahead of print]

Mock A, Geisenberger C, Orlik C, Warta R, Schwager C, Jungk C, Dutruel C, Geiselhart L, Weichenhan D, Zucknick M, Nied AK, Friauf S, Exner J, Capper D, Hartmann C, Lahrmann B, Grabe N, Debus J, von Deimling A, Popanda O, Plass C, Unterberg A, Abdollahi A, Schmezer P, Herold-Mende C:

LOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients.

Int J Cancer 2016; 139(2): 424-432

Mulay SR, Desai J, Kumar SV, Eberhard JN, Thomasova D, Romoli S, Grigorescu M, Kulkarni OP, Popper B, Vielhauer V, Zuchtriegel G, Reichel C, Bräsen JH, Romagnani P, Bilyy R, Munoz LE, Herrmann M, Liapis H, Krautwald S, Linkermann A, Anders HJ:

Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis.

Nat Commun 2016; 7: 10274

Mossner M, Jann JC, Nowak D, Platzbecker U, Giagounidis A, Götze K, Letsch A, Haase D, Shirneshan K, Braulke F, Schlenk RF, Haferlach T, Schafhausen P, Bug G, Lübbert M, Ganser A, Büsche G, Schuler E, Nowak V, Pressler J, Obländer J, Fey S, Müller N, Lauinger-Lörsch E, Metzgeroth G, Weiß C, Hofmann WK, Germing U, Nolte F:

Prevalence, clonal dynamics and clinical impact of TP53 mutations in patients with myelodysplastic syndrome with isolated deletion (5q) treated with lenalidomide: results from a prospective multicenter study of the german MDS study group (GMDS).

Leukemia 2016; 30(9): 1956-1959 [Letter]

Nadiradze G, Giger-Pabst U, Zieren J, Strumberg D, Solass W, Reymond MA:

Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) with Low-Dose Cisplatin and Doxorubicin in Gastric Peritoneal Metastasis.

J Gastrointest Surg 2016; 20(2): 367-373

Olschewski A, Berghausen EM, Eichstaedt CA, Fleischmann BK, Grünig E, Grünig G, Hansmann G, Harbaum L, Hennigs JK, Jonigk D, Kübler WM, Kwapiszewska G, Pullamsetti SS, Stacher E, Weissmann N, Wenzel D, Schermuly RT:

[Pathobiology, pathology and genetics of pulmonary hypertension: Recommendations of the Cologne Consensus Conference 2016].

Dtsch Med Wochenschr 2016; 141(S 01): S4-S9

Olsson KM, Olle S, Fuge J, Welte T, Hoeper MM, Lerch C, Maegel L, Haller H, Jonigk D, Schiffer L:

CXCL13 in idiopathic pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

Respir Res 2016; 17(1): 21

Otte A, Yang Y, von der Ohe J, Melzer C, Hillemanns P, Feuerhake F, Hass R:

SCCOHT tumors acquire chemoresistance and protection by interacting mesenchymal stroma/stem cells within the tumor microenvironment.

Int J Oncol. 2016 Oct 14. doi: 10.3892/ijo.2016.3735. [Epub ahead of print]

Petrakakis I, Pirayesh A, Krauss JK, Raab P, Hartmann C, Nakamura M:

The sellar and suprasellar region: A "hideaway" of rare lesions. Clinical aspects, imaging findings, surgical outcome and comparative analysis.

Clin Neurol Neurosurg 2016; 149: 154-165

Pils MC, Dreckmann K, Jansson K, Glage S, Held N, Sommer W, Länger F, Avsar M, Warnecke G, Bleich A:

Mortality Due to Porcine Reproductive and Respiratory Syndrome Virus in Immunocompromised Göttingen Minipigs (Sus scrofa domestica).

Comp Med 2016; 66(5): 392-398

Poehnert D, Grethe L, Maegel L, Jonigk D, Lippmann T, Kaltenborn A, Schrem H, Klempnauer J, Winny M:

Evaluation of the Effectiveness of Peritoneal Adhesion Prevention Devices in a Rat Model.

Int J Med Sci 2016; 13(7): 524-532

Rafikova O, Rafikov R, Kangath A, Qu N, Aggarwal S, Sharma S, Desai J, Fields T, Ludewig B, Yuan JX, Jonigk D, Black SM:

Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension.

Free Radic Biol Med 2016; 95: 96-111

Riehle M, Büscher AK, Gohlke BO, Kaßmann M, Kolatsi-Joannou M, Bräsen JH, Nagel M, Becker JU, Winyard P, Hoyer PF, Preissner R, Krautwurst D, Gollasch M, Weber S, Harteneck C:

TRPC6 G757D Loss-of-Function Mutation Associates with FSGS.

J Am Soc Nephrol. 2016 Feb 18. pii: ASN.2015030318. [Epub ahead of print]

Röhrich M, Koelsche C, Schrimpf D, Capper D, Sahm F, Kratz A, Reuss J, Hovestadt V, Jones DT, Bewerunge-Hudler M, Becker A, Weis J, Mawrin C, Mittelbronn M, Perry A, Mautner VF, Mechtersheimer G, Hartmann C, Okuducu AF, Arp M, Seiz-Rosenhagen M, Hänggi D, Heim S, Paulus W, Schittenhelm J, Ahmadi R, Herold-Mende C, Unterberg A, Pfister SM, von Deimling A, Reuss DE:

Methylation-based classification of benign and malignant peripheral nerve sheath tumors.

Acta Neuropathol 2016; 27(9): 2771-2783

Rüschoff J, Lebeau A, Kreipe H, Sinn P, Gerharz CD, Koch W, Morris S, Ammann J, Untch M; Nicht-interventionelle Untersuchung (NIU) HER2 Study Group..

Assessing HER2 testing quality in breast cancer: variables that influence HER2 positivity rate from a large, multicenter, observational study in Germany.

Mod Pathol. 2016 Oct 21. doi: 10.1038/modpathol.2016.164. [Epub ahead of print]

Salari A, Thomay K, Himmler K, Vajen B, Schienke A, Hagedorn M, Ebersold J, Kreipe HH, Krüger A, Schambach A, Schlegelberger B, Göhring G:

Establishing a murine xenograft-model for long-term analysis of factors inducing chromosomal instability in myelodysplastic syndrome: Pitfalls and successes.

Cancer Genet 2016; 209(6): 258-266

Schlenk RF, Stegelmann F, Reiter A, Jost E, Gattermann N, Hebart H, Waller C, Hochhaus A, Platzbecker U, Schafhausen P, Blau IW, Verbeek W, Heidel FH, Werner M, Kreipe H, Teleanu V, Benner A, Döhner H, Grießhammer M, Döhner K:

Pomalidomide in myeloproliferative neoplasm-associated myelofibrosis.

Leukemia. 2016 Oct 24. doi: 10.1038/leu.2016.299. [Epub ahead of print]

Schieck M, Schouten JP, Michel S, Suttner K, Toncheva AA, Gaertner VD, Illig T, Lipinski S, Franke A, Klintschar M, Kalayci O, Sahiner UM, Birben E, Melén E, Pershagen G, Freidin MB, Ogorodova LM, Granell R, Henderson J, Brunekreef B, Smit HA, Vogelberg C, von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Genuneit J, Jonigk D, Postma DS, Koppelman GH, Vonk JM, Timens W, Boezen HM, Kabesch M:

Doublesex and mab-3 related transcription factor 1 (DMRT1) is a sex-specific genetic determinant of childhood-onset asthma and is expressed in testis and macrophages.

J Allergy Clin Immunol 2016; 138(2): 421-431

Schiffgens S, Wilkens L, Brandes AA, Meier T, Franceschi E, Ermani M, Hartmann C, Sandalcioglu IE, Dumitru CA:

Sex-specific clinicopathological significance of novel (Frizzled-7) and established (MGMT, IDH1) biomarkers in glioblastoma.

Oncotarget 2016; 7(34): 55169-55180

Schliesser MG, Claus R, Hielscher T, Grimm C, Weichenhan D, Blaes J, Wiestler B, Hau P, Schramm J, Sahm F, Weiß EK, Weiler M, Baer C, Schmidt-Graf F, Schackert G, Westphal M, Hertenstein A, Roth P, Galldiks N, Hartmann C, Pietsch T, Felsberg J, Reifenberger G, Sabel MC, Winkler F, von Deimling A, Meisner C, Vajkoczy P, Platten M, Weller M, Plass C, Wick W:

Prognostic relevance of miRNA-155 methylation in anaplastic glioma.

Oncotarget. 2016 Nov 18. doi: 10.18632/oncotarget.13452. [Epub ahead of print]

Schmidt H, Michel C, Braubach P, Fauler M, Neubauer D, Thompson KE, Frick M, Mizaikoff B, Dietl P, Wittekindt OH:

Water Permeability Adjusts Resorption in Lung Epithelia to Increased Apical Surface Liquid Volumes.

Am J Respir Cell Mol Biol. 2016 Nov 4. [Epub ahead of print]

Schneider RK, Schenone M, Ferreira MV, Kramann R, Joyce CE, Hartigan C, Beier F, Brümmendorf TH, Germing U, Platzbecker U, Büsche G, Knüchel R, Chen MC, Waters CS, Chen E, Chu LP, Novina CD, Lindsley RC, Carr SA, Ebert BL:

Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9.

Nat Med 2016; 22(3): 288-297

Schuler E, Giagounidis A, Haase D, Shirneshan K, Büsche G, Platzbecker U, Nolte F, Götze K, Schlenk RF, Ganser A, Letsch A, Braulke F, Lübbert M, Bug G, Schafhausen P, Bacher U, Gattermann N, Wulfert M, Haas R, Germing U:

Results of a multicenter prospective phase II trial investigating the safety and efficacy of lenalidomide in patients with myelodysplastic syndromes with isolated del(5q) (LE-MON 5).

Leukemia 2016; 30(7): 1580-1582

Schrem H, Focken M, Gunson B, Reichert B, Mirza D, Kreipe HH, Neil D, Kaltenborn A, Goldis A, Krauth C, Roberts K, Becker T, Klempnauer J, Neuberger J:

The new liver allocation score (LivAS) for transplantation is validated in germany improving transplant survival benefit but not in the UK.

Liver Transpl 2016; 22(6): 743-756

Siemeni T, Knöfel AK, Madrahimov N, Sommer W, Avsar M, Salman J, Ius F, Frank N, Büchler G, Jonigk D, Jansson K, Maus U, Tudorache I, Falk CS, Haverich A, Warnecke G:

In Vivo Development of Transplant Arteriosclerosis in Humanized Mice Reflects Alloantigen Recognition and Peripheral Treg Phenotype of Lung Transplant Recipients.

Am J Transplant 2016; 16(11): 3150-3162

Spalthoff S, Bredt M, Gellrich NC, Jehn P:

A Rare Pathology: Low-Grade Fibromyxoid Sarcoma of the Maxilla.

J Oral Maxillofac Surg 2016; 74(1): 219.e1-219.e10 [Case Report]

Stefanits H, Bienkowski M, Galanski M, Mitulovic G, Ströbel T, Gelpi E, Ribalta T, Broholm H, Hartmann C, Kros JM, Preusser M, Hainfellner JA:

KINFix - A formalin-free non-commercial fixative optimized for histological, immunohistochemical and molecular analyses of neurosurgical tissue specimens.

Clin Neuropathol 2016; 35(1): 3-12

Suhling H, Gottlieb J, Bara C, Taubert R, Jäckel E, Schiffer M, Bräsen JH:

[Chronic rejection : Differences and similarities in various solid organ transplants].

Internist (Berl) 2016; 57(1): 25-37 [German]

Tempfer CB, El Fizazi N, Ergonenc H, Solass W:

Metastasis of ovarian cancer to the breast: A report of two cases and a review of the literature.

Oncol Lett 2016; 11(6): 4008-4012

Vondran FW, Schumacher C, Johanning K, Hartleben B, Knitsch W, Wiesner O, Jaeckel E, Manns MP, Klempnauer J, Bektas H, Lehner F:

Application of the Liver Maximum Function Capacity Test in Acute Liver Failure: A Helpful Tool for Decision-Making in Liver Transplantation?

Case Rep Transplant 2016; 2016: 7074636

Warth A, Länger F:

[Report of the working group Thoracic Pathology of the German Pathological Society 2016].

Pathologe 2016; 37(Suppl 2): 253-255

Weissinger EM, Human C, Metzger J, Hambach L, Wolf D, Greinix HT, Dickinson AM, Mullen W, Jonigk D, Kuzmina Z, Kreipe H, Schweier P, Böhm O, Türüchanow I, Ihlenburg-Schwarz D, Raad J, Durban A, Schiemann M, Könecke C, Diedrich H, Holler E, Beutel G, Krauter J, Ganser A, Stadler M:

The proteome pattern cGvHD_MS14 allows early and accurate prediction of chronic GvHD after allogeneic stem cell transplantation.

Leukemia. 2016 Nov 4. doi: 10.1038/leu.2016.259. [Epub ahead of print]

Wick W, Roth P, Hartmann C, Hau P, Nakamura M, Stockhammer F, Sabel MC, Wick A, Koeppen S, Ketter R, Vajkoczy P, Eyupoglu I, Kalff R, Pietsch T, Happold C, Galldiks N, Schmidt-Graf F, Bamberg M, Reifenberger G, Platten M, von Deimling A, Meisner C, Wiestler B, Weller M; Neurooncology Working Group (NOA) of the German Cancer Society..

Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide.

Neuro Oncol 2016; 18(11): 1529-1537. Erratum in: Neuro Oncol. 2016 Nov;18(11):e1.

Winny M, Grethe L, Maegel L, Jonigk D, Lippmann T, Klempnauer J, Poehnert D:

Impairment of the Peritoneal Surface as a Decisive Factor for Intestinal Adhesions in Intraperitoneal Onlay Mesh Surgery - Introducing a New Rat Model.

Int J Med Sci 2016; 13(2): 108-112

Wimmer K, Beilken A, Nustede R, Ripperger T, Lamottke B, Ure B, Steinmann D, Reineke-Plaass T, Lehmann U, Zschocke J, Valle L, Fauth C, Kratz CP:

A novel germline POLE mutation causes an early onset cancer prone syndrome mimicking constitutional mismatch repair deficiency.

Fam Cancer. 2016 Aug 29. [Epub ahead of print]

Zhang R, Bures M, Höffler K, Jonigk D, Haverich A, Krueger M:

In Vitro Comparison of Two Widely Used Surgical Sealants for Treating Alveolar Air Leak.

Thorac Cardiovasc Surg. 2016 Dec 31. doi: 10.1055/s-0036-1597906. [Epub ahead of print] No abstract available.

Zhang R, Mägel L, Jonigk D, Länger F, Lippmann T, Zardo P, Pölzing F:

Biosynthetic Nanostructured Cellulose Patch for Chest Wall Reconstruction: Five-Month Follow-up in a Porcine Model.

J Invest Surg. 2016 Oct 21:1-6. [Epub ahead of print]

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