Publikationen

 

Pathways to Clinical Cardiac Xenotransplantation.
Reichart B, Längin M, Denner J, Schwinzer R, Cowan PJ, Wolf E.
Transplantation. 2021 Sep 1;105(9):1930-1943. doi: 10.1097/TP.0000000000003588.

Generating low immunogenic pig pancreatic islet cell clusters for xenotransplantation
Carvalho Oliveira M, Valdivia E, Verboom M, Yuzefovych Y, Sake HJ, Pogozhykh O, Niemann H, Schwinzer R, Petersen B, Seissler J, Blasczyk R, Figueiredo C
J Cell Mol Med. 2020 May; 24(9): 5070–5081. Published online 2020 Mar 25. doi: 10.1111/jcmm.15136

Triple (GGTA1, CMAH, B2M) modified pigs expressing an SLA class Ilow phenotype-Effects on immune status and susceptibility to human immune responses.
Hein R, Sake HJ, Pokoyski C, Hundrieser J, Brinkmann A, Baars W, Nowak-Imialek M, Lucas-Hahn A, Figueiredo C, Schuberth HJ, Niemann H, Petersen B, Schwinzer R.
Am J Transplant. 2020 Apr;20(4):988-998. doi: 10.1111/ajt.15710. Epub 2019 Dec 28.

Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2.
Fischer K, Rieblinger B, Hein R, Sfriso R, Zuber J, Fischer A, Klinger B, Liang W, Flisikowski K, Kurome M, Zakhartchenko V, Kessler B, Wolf E, Rieben R, Schwinzer R, Kind A, Schnieke A.
Xenotransplantation. 2020 Jan;27(1):e12560. doi: 10.1111/xen.12560. Epub 2019 Oct 8.

Possible detrimental effects of beta-2-microglobulin knockout in pigs.
Sake HJ, Frenzel A, Lucas-Hahn A, Nowak-Imialek M, Hassel P, Hadeler KG, Hermann D, Becker R, Eylers H, Hein R, Baars W, Brinkmann A, Schwinzer R, Niemann H, Petersen B.
Xenotransplantation. 2019 May 22:e12525. doi: 10.1111/xen.12525. [Epub ahead of print]

Role of human and porcine MHC DRB1 alleles in determining the intensity of individual human anti-pig T-cell responses.
Hundrieser J, Hein R, Pokoyski C, Brinkmann A, Düvel H, Dinkel A, Trautewig B, Siegert JF, Römermann D, Petersen B, Schwinzer R.
Xenotransplantation. 2019 Jul;26(4):e12523. doi: 10.1111/xen.12523. Epub 2019 May 9.

Pigs expressing the human inhibitory ligand PD-L1 (CD 274) provide a new source of xenogeneic cells and tissues with low immunogenic properties.
Buermann A, Petkov S, Petersen B, Hein R, Lucas-Hahn A, Baars W, Brinkmann A, Niemann H, Schwinzer R.
Xenotransplantation. 2018 Sep;25(5):e12387. doi: 10.1111/xen.12387. Epub 2018 Feb 15.