DEGREES AND ACADEMIC CAREER:
| Since 2019 | Junior PI, Hannover Medical School, Department of Cellular Neurophysiology |
| 2013 – 2019 | Postdoctoral researcher, Hannover Medical School, Cellular Neurophysiology |
| 2009 – 2013 | Dr. rer. nat., Charité-Universitätsmedizin Berlin, Institute for Biochemistry |
| 2004 – 2009 | Diploma in biochemistry, Free University Berlin |
RESEARCH INTERESTS:
- Mechanisms inducing accumulation of misfolded proteins in neurodegenerative diseases
- Serotonin receptor-mediated signaling in neuronal morphology and synaptic plasticity
- Extracellular matrix and adhesion receptors
EXPERTISE:
Quantitative molecular microscopy approaches to analyze:
- intracellular signaling pathways (FRET-based biosensors for cAMP, GTPases)
- protein-protein interactions (lux-FRET approach)
- neuronal morphology and synaptic plasticity
- extracellular matrix remodeling (MMP-9 biosensor, shedding reporters)
Biochemical approaches to study:
- pathological protein aggregation
- post-translational modifications (in particular palmitoylation)
- cell-matrix adhesion
Adeno-associated virus production
Mouse models of dementia, behavioral testing for cognition and locomotion