the small GTPase Rac1 is activated after receptor internalization which is key for the IL-1-induced gene expression. The small GTPase Rac1 is an endosome-specific “sorting adaptor” in IL-1 signaling. However

Prof. Dr. Halyna Shcherbata EMBO Young Investigator Research Group Gene Expression and Signaling Institute of Cell Biochemistry Hannover Medical School Carl-Neuberg-Strasse 1 30625 Hannover Germany OE

sowie der Charakterisierung von genetischen Polymorphismen von mit der Immunantwort assoziierten Genen. Sie beschäftigt sich außerdem mit erworbenen Gerinnungsstörungen im Kindesalter, z.B. dem von-Wi

family. The name DPY-19 comes from the worm C. elegans, where mutations in the C-mannosyltransferase gene lead to a temperature-sensitive DumPY phenotype. In humans there are four homologs of DPY-19, which

Master thesis work MDPhD Molecular Medicine, Hannover Medical School Lecture and seminar: "T-box genes in development and disease", 2nd semester PhD thesis PhD Regenerative Sciences, Hannover Medical School

Schweitzer N, Vogel A, Kreipe H , Lehmann U : Concordant hypermethylation of intergenic microRNA genes in human hepatocellular carcinoma as new diagnostic and prognostic marker. Int J Cancer 2013; 133(3): [...] Länger F , Kreipe H , Lehmann U : Oncogenic PIK3CA mutations in lobular breast cancer progression. Genes Chromosomes Cancer 2013; 52(1): 69-80 Eminaga O, Hinkelammert R, Abbas M , Titze U, Eltze E, Bettendorf [...] Transplantation 2013; 95(2): 285-292 Hussein K , Granot G, Shpilberg O, Kreipe H : Clinical utility gene card for: familial polycythaemia vera. Eur J Hum Genet 2013; 21(6). doi: 10.1038/ejhg.2012.216. No

(Experimental Hematology) Project: Development of novel tissue-specific AAV vectors for neuromuscular gene therapies Subham Rana , INDIA, Subham.Rana @ mh-hannover.de Supervisor: Prof. Dr. Christian Bär / [...] Lily@mh-hannover.de Supervisor: Prof. Dr. Ruthhild Weber (Human Genetics) Project: Ribosomal biogenesis genes and predisposition to brain tumors Tirthankar Saha , INDIA, Saha.Tirthankar@mh-hannover.de Supervisor:

REBIRTH, OE 8882, project: Transgenic expression of cytidine deaminase (CDD) and multidrug resistance gene 1 (MDR1) to optimise treatment strategies for acute leukemias and the myelodysplastic syndrome (MDS) [...] Dr. Anuhar Chaturvedi, Molecular Therapy, OE 6864, project: Transcriptional control of MN1 target genes Final exam June 2016. Eileen Hübschen (nee Frenzel) GERMANY supervisor: Prof. Dr. Janciauskiene,

Leistungsförderung (HiLF): “Untersuchung zur Veränderlichkeit der Methylierung des Proopiomelanocortin-GenPromotors und der konsekutiven Expression seines Derivats, AlphaMelanozytenstimulierendes-Hormon, bei [...] Analyseverfahren Erforschung der Alkoholabhängigkeit und anderer stofflichen Drogen Regulation von Genen in Blut und Gehirn Publikationen: Pubmed Prof. Dr. med. Thomas Hillemacher Ärztlicher Leiter der

K. and T.J. Smith, Genetic diversity within Clostridium botulinum serotypes, botulinum neurotoxin gene clusters and toxin subtypes. Curr Top Microbiol Immunol, 2013. 364 : p. 1-20. [5] Montecucco, C. and [...] 183-91. [8] Dover, N., et al., Molecular characterization of a novel botulinum neurotoxin type H gene. J Infect Dis, 2014. 209 (2): p. 192-202. [9] Gonzalez-Escalona, N., et al., Draft Genome Sequence [...] bioRxiv, 2017: p. 228098. [13] Brunt, J., et al., Identification of a novel botulinum neurotoxin gene cluster in Enterococcus. FEBS Lett, 2018. [14] Zhang, S., et al., Identification of a Botulinum N