studies in small and large animals. IMTTS also works closely together with the Hannover Clinical Research Center (CRC; https://www.crc-hannover.com/ ), the Fraunhofer ITEM ( https://www.item.fraunhofer [...] licensed IMTTS technology to develop innovative ncRNA-based treatment strategies and to perform first clinical trials in cardiovascular patients. Research Groups: Cardiovascular Phenotyping and Translational

University Wexner Medical Center, Columbus, USA Dr. Krishna Chintalapudi (2007-2011 Dr. rer. nat. in the Manstein group) Assistant Professor, The Ohio State University Wexner Medical Center, Columbus, USA Dr. [...] Hennig (2008-2013 Dr. rer. nat. in the Korenbaum & Manstein groups) Research Associate, Molecular and Clinical Infection Biology, Tierärztliche Hochschule Hannover, Hannover Prof. Dr. Matthias Preller (2009-2012 [...] Hochschule Bonn-Rhein-Sieg Dr. Dr. Mirco Müller- Olling (2009-2013 Dr. rer. nat. in the Manstein group) Clinical Development Lead, Roche, Mannheim, Germany Dr. Michael Radke (2010-2013 Dr. rer. nat. in the Manstein

Research Group Personalised Immunotherapy Prof. Dr. Kathrin de la Rosa TWINCORE - Center for Experimental and Clinical Infection Research Institute of Experimental Virology Prof. Dr. Thomas Pietschmann [...] Animal Science Prof. Dr. Andre Bleich Dr. Manuela Büttner Prof. Dr. Hans Hedrich Rheumatology and Clinical Immunology Prof. Dr. Georg Behrens Prof. Dr. Roland Jacobs Georgios Sogkas, PhD Prof. Dr. Torsten [...] Prof. Dr. Meike Stiesch Institute of Experimental Hematology Prof. Dr. med. Axel Schambach, PhD Clinical Bioinformatics (CiiM) Prof. Dr. Cheng-Jian Xu Helmholtz Centre for Infection Research, Braunschweig

Ihnen im Clinical Research Center Hannover eine vollausgestattete und für die MHH bereits seit 2014 mit unverändertem Early Phase Medical Team arbeitende klinisch-operativ aktive Early Clinical Trial Unit

that, in appropriate clinical circumstances, can be used as a surrogate for direct viral detection for diagnostic purposes? What are those clinical circumstances? Can discrete clinical phenotypes be identified [...] edition of the AAN clinical practice guideline development process manual. An international, multidisciplinary panel of investigators with expertise in virology, immunology, clinical neurology, neuroradiology [...] reviewed and re-evaluated. The SR will inform consensus recommendations. Clinical questions for the systematic review Are there clinical phenotypes that strongly suggest PML and mandate clinicians to explore

mit gesunden Probanden und Patienten mit Atemwegserkrankungen durch. Durch das neu erbaute Clinical Research Center (CRC) auf dem Gelände des Fraunhofer-Instituts sind vermehrt klinische Prüfungen in frühen [...] er intensiv überwacht werden und sich über mehrere Tage im Zentrum aufhalten können. Ein Imaging-Center, eine Biobank und ein GCP-konformes Biomarker-Labor im CRC erlauben die Untersuchung und Entwicklung

in suspension culture. The third industrial partner in the alliance, KADIMASTEM, is working on clinical- and regulatory-compliant processes for the cultivation and differentiation of hiPSCs. The academic [...] cell survival after transplantation. Since safety aspects of cell therapies play a central role in clinical translation, the partner lab at the University of Sheffield (UK) is involved in examining the p [...] the different cell types will be bundled at the MHH. Under the guidance of The University Medical Center Utrecht these tissues are transplanted for preclinical testing into damaged hearts in animal models

Medical School (MHH), Hanover, Germany since 1998 as well as board member of the Transplantation Center at Hannover Medical School since 2019. He graduated in medicine from the Universities Bochum and [...] ation immunology with a main focus on transplant tolerance and transplant engineering. His work centers around the alloimmune response in organ transplantation and therapeutic interventions to combat rejection [...] systems in order to identify therapeutic targets for graft engineering to substantially improve clinical outcome of transplantation. Professor Blasczyk has initiated the Research Network on Invisible Organs

Medical School (MHH), Hanover, Germany since 1998 as well as board member of the Transplantation Center at Hannover Medical School since 2019. He graduated in medicine from the Universities Bochum and [...] ation immunology with a main focus on transplant tolerance and transplant engineering. His work centers around the alloimmune response in organ transplantation and therapeutic interventions to combat rejection [...] systems in order to identify therapeutic targets for graft engineering to substantially improve clinical outcome of transplantation. Professor Blasczyk has initiated the Research Network on Invisible Organs

Medical School (MHH), Hanover, Germany since 1998 as well as board member of the Transplantation Center at Hannover Medical School since 2019. He graduated in medicine from the Universities Bochum and [...] ation immunology with a main focus on transplant tolerance and transplant engineering. His work centers around the alloimmune response in organ transplantation and therapeutic interventions to combat rejection [...] for Immunogenetics (EFI) 2007 – 2014 Scientific Advisory Board, Integrated Research and Treatment Center Transplantation (IFB-Tx), Hannover Medical School, Germany 2009 – 2019 Scientific Advisory Board