e Therapie Pharmakologie Klinische Pharmakologie Psychopharmakologie Grundlagenwissenschaften Humangenetik Zentrallabor Biochemie Glykoanalytik Biometrie Neuroanatomie Psyche Psychiatrie Psychosomatik
important drug targets was considered to be a remote idea more than twenty years ago. Meanwhile, the human kinome is known and the spectacular therapeutic results obtained with STI571 (Gleevec) , suggested
lle Hämatologie) Prof. Dr. Lars Dölken (Virologie) Prof. Dr. Nataliya Di Donato (Institut für Humangenetik) Prof. Dr. Anna-Maria Dittrich (Pädiatrische Pneumologie) Prof. Dr. Meike Stiesch (Klinik für
Stippel D, Flemming P, Nussbaum T, Caselmann WH, Haab BB, Schirmacher P: Molecular profiling of human hepatocellular carcinoma defines mutually exclusive interferon regulation and insulin-like growth [...] Mengel M, Merkel S, Banas B, Luft FC, Haller H: Growth arrest specific protein 6/Axl signaling in human inflammatory renal diseases. Am J Kidney Dis 2004; 43(2): Giagounidis AA, Germing U, Haase S, Hildebrandt [...] W, Wagner S: Effect of H. pylori on the expression of TRAIL, FasL and their receptor subtypes in human gastric epithelial cells and their role in apoptosis. Helicobacter 2004; 9(5): 371-86 Mengel M, Jonigk
H. C. ; Bergforth,W. ; Przykopanski,A. ; Rummel,A. ; Klawonn,F. ; Seeger,B. Human-Relevant Sensitivity of iPSC-Derived Human Motor Neurons to BoNT/A1 and B1, Switzerland,Toxins (Basel),2021;13(8):585- [...] Arjang ; Fiedler,Jan ; Weber,Natalie ; Thum,Thomas ; Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo Eur.Heart J., 2024, 45(22), 2016- 2018, Originalpublikation Albers,Marco [...] Tsikas,Dimitrios ; Kuczyk,Markus A. ; Ückert,Stefan ; Drugs to affect the smooth musculature of the human ureter - an update with integrated information from basic science to the use in medical expulsion
alveolar lung organoids obtained either from murine adult stem cells or via directed differentiation of human iPS cells into functional type 2 alveolar epithelial cells. By co-culturing immune and structural [...] H. B. 2020. Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis. Nat Commun 11, no. 1:3559. https://doi.org/10.1038/s41467-020-17358-3 .
occurring endogenous and adoptively transferred antiviral T cells in optimizing T-cell immunity against human polyomavirus 1 (BKPyV, BKV) to avoid allograft dysfunction in kidney transplant recipients Friederike [...] speaker! Lily Sophie Rose , GERMANY, Rose.Lily@mh-hannover.de Supervisor: Prof. Dr. Ruthhild Weber (Human Genetics) Project: Ribosomal biogenesis genes and predisposition to brain tumors Tirthankar Saha
Thum / Dr. Christian Bär (IMTTS) Project: Screening and validation of natural compound libraries in human iPSC-cardiomyocytes for the treatment of Fabry disease Final exam June 2024 Bushra Khan INDIA khan [...] Jonathan Lühmann GERMANY Luehmann.Jonathan @ mh-hannover.de Supervisor: Prof. Dr. Doris Steinemann (Human Genetics) Project: Optical Mapping to detect structural genomic variants in cancer Jonathan was class
P, Fieguth HG, Wilkens L, Braun A, Hessel EM, Sewald K; U-BIOPRED Study Group. Rhinovirus-induced Human Lung Tissue Responses Mimic COPD and Asthma Gene Signatures. Am J Respir Cell Mol Biol. 2021 Jun 28 [...] Martin C, Braun A, Sewald K. Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices. J Vis Exp. 2018 May 9;(135):57042. doi: 10.3791/57042. PMID: 29806827;
Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie und der Institute Pathologie und Humangenetik wollen in ihrem Projekt den Mehrwert von unterschiedlichen liquid biopsies aus der Gallenflüssigkeit [...] und es kann Krebs entstehen. Zu den häufigsten viralen Verursachern für Krebserkrankungen zählen humane Papillomaviren (HPV), das Epstein-Bar-Virus (EBV) und Hepatitis-Viren (HBV/ HCV). Ein Forschungsteam