H. C. ; Bergforth,W. ; Przykopanski,A. ; Rummel,A. ; Klawonn,F. ; Seeger,B. Human-Relevant Sensitivity of iPSC-Derived Human Motor Neurons to BoNT/A1 and B1, Switzerland,Toxins (Basel),2021;13(8):585- [...] Arjang ; Fiedler,Jan ; Weber,Natalie ; Thum,Thomas ; Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo Eur.Heart J., 2024, 45(22), 2016- 2018, Originalpublikation Albers,Marco [...] Tsikas,Dimitrios ; Kuczyk,Markus A. ; Ückert,Stefan ; Drugs to affect the smooth musculature of the human ureter - an update with integrated information from basic science to the use in medical expulsion
alveolar lung organoids obtained either from murine adult stem cells or via directed differentiation of human iPS cells into functional type 2 alveolar epithelial cells. By co-culturing immune and structural [...] H. B. 2020. Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis. Nat Commun 11, no. 1:3559. https://doi.org/10.1038/s41467-020-17358-3 .
occurring endogenous and adoptively transferred antiviral T cells in optimizing T-cell immunity against human polyomavirus 1 (BKPyV, BKV) to avoid allograft dysfunction in kidney transplant recipients Friederike [...] speaker! Lily Sophie Rose , GERMANY, Rose.Lily@mh-hannover.de Supervisor: Prof. Dr. Ruthhild Weber (Human Genetics) Project: Ribosomal biogenesis genes and predisposition to brain tumors Tirthankar Saha
Thum / Dr. Christian Bär (IMTTS) Project: Screening and validation of natural compound libraries in human iPSC-cardiomyocytes for the treatment of Fabry disease Final exam June 2024 Bushra Khan INDIA khan [...] Jonathan Lühmann GERMANY Luehmann.Jonathan @ mh-hannover.de Supervisor: Prof. Dr. Doris Steinemann (Human Genetics) Project: Optical Mapping to detect structural genomic variants in cancer Jonathan was class
P, Fieguth HG, Wilkens L, Braun A, Hessel EM, Sewald K; U-BIOPRED Study Group. Rhinovirus-induced Human Lung Tissue Responses Mimic COPD and Asthma Gene Signatures. Am J Respir Cell Mol Biol. 2021 Jun 28 [...] Martin C, Braun A, Sewald K. Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices. J Vis Exp. 2018 May 9;(135):57042. doi: 10.3791/57042. PMID: 29806827;
Gastroenterologie, Hepatologie, Infektiologie und Endokrinologie und der Institute Pathologie und Humangenetik wollen in ihrem Projekt den Mehrwert von unterschiedlichen liquid biopsies aus der Gallenflüssigkeit [...] und es kann Krebs entstehen. Zu den häufigsten viralen Verursachern für Krebserkrankungen zählen humane Papillomaviren (HPV), das Epstein-Bar-Virus (EBV) und Hepatitis-Viren (HBV/ HCV). Ein Forschungsteam
Investigation of noncoding RNA pathways for the treatment of Fabry disease using patient-derived human iPSC-cardiomyocytes. Final exam June 2023 Mi-Sun Jang GERMANY Jang.Mi-Sun@mh-hannover.de Supervisor: [...] Prof. Dr. Nico Lachmann, Pediatric Pneumology Project: Dissecting the onset of macrophages from human iPSC for disease modelling and therapeutic applications Juliette Nowak GERMANY Supervisors: from September
Rahmen der Lehrveranstaltung bekannt gegeben. WP 31 - Molekulare Humangenetik Human molecular genetics Strachan, T. Molekulare Humangenetik Strachan, T. WP 32 - Molekulare Mikrobiologie für Biochemiker Biology
PYA, Zattelman L, Fedorov R, Henn A, Taft MH & Manstein DJ. (2020). Mechanochemical properties of human myosin 1C are modulated by isoform-specific differences in the N-terminal extension. J Biol Chem. [...] n R, and Fedorov R. A Quaternary Mechanism Enables the Complex Biological Functions of Octameric Human UDP-glucose Pyrophosphorylase, a Key Enzyme in Cell Metabolism. (2015) Sci. Rep . 5 , 9618; DOI:10 [...] Schneider J, Münster-Kühnel AK, Gerardy-Schahn R. Octamerization is essential for enzymatic function of human UDP-glucose pyrophosphorylase. (2013) Glycobiology . 23 (4):426-37. Heissler SM, Selvadurai J, Bond
in the Cal-51 human breast carcinoma cell line. Mol Cell Biochem 2007; 306(1-2): 201-12 Christgen M, Lehmann U: MDA-MB-435: The questionable use of a melanoma cell line as a model for human breast cancer [...] 110(12): 3949-58 Becker JU, Hoerning A, Schmid KW, Hoyer PF: Immigrating progenitor cells contribute to human podocyte turnover. Kidney Int 2007; 72(12): 1468-73 Bock O, Hussein K, Brakensiek K, Buhr T, Schlué [...] Roncalli M, Rudolph KL: Telomere shortening and inactivation of cell cycle checkpoints characterize human hepatocarcinogenesis. Hepatology 2007; 45(4): 968-76 Solez K, Colvin RB, Racusen LC, Sis B, Halloran