Uhr MM-Schwerpunktsprechstunde PD Dr. A. Brioli / Dr. K. Brinkert MM-Gerinnungssprechstunde Prof. Dr. A. Tiede / Dr. C. Dobbelstein MM-CAR-T-Sprechstunde PD Dr. A. Brioli / PD Dr. C. Schultze-Florey A

ligase TRAF2. Cell Death Dis. 14(7):480. doi: 10.1038/s41419-023-06014-5. Stutz A, Nishanth G , Zenclussen AC, Schumacher A(2022) Partial otubain 1 deficiency compromises fetal well-being in allogeneic [...] Handschuh J, Müller P, Li J, Harit K, Nishanth G , Frey S, Böttcher M, Fischer KD, Dudeck J, Dudeck A, Lipka DB, Schraven B, Green AR, Müller AJ, Mougiakakos D, Fischer T.J (2024) Neutrophil-specific expression [...] Notes. 15(1):341. doi: 10.1186/s13104-022-06230-w. Koschel J, Nishanth G* , Just S, Harit K, Kröger A, Deckert M, Naumann M, Schlüter D * (2021). OTUB1 prevents lethal hepatocyte necroptosis through st

Functional characterizations of mutations in non-muscle myosin-2A causing MYH9 -related disorders Characterization of SH3BGRL proteins, a group of newly discovered actin pointed-end capping proteins Structural

research on transplant engineering. Professor Blasczyk has a long term research interest in solid organ transplantation and transplantation immunology with a main focus on transplant tolerance and transplant [...] tolerance. Professor Blasczyk is founder and chairman of the Immunotherapy Foundation. He has been a member of the Advisory Board on Blood Products of the German Ministry of Health, President of the German [...] Immunogenetics (DGI) and the German Society of Transfusion Medicine and Immunohematology (DGTI) as well as a Board Member of the European Society of Immunogenetics (EFI). CURRICULUM VITAE Education and Professional

Aussicht gestellten PSMA PET zu ersparen, listen wir hier noch einmal die genannten Kriterien auf: ASV URO A1: Nach Prostatektomie, fehlender PSA-Abfall (weniger als 0,2 ng/ml) nach 3 Monaten bei 2 Messungen. [...] ie nicht die tatsächliche Tumorlokalisation adressiert (z. B. „out of field“ Bestrahlung). ASV URO A2: Nach alleiniger Prostatektomie (PSA erhöht in 2 Messungen über 0,2 ng/ml) oder nach alleiniger Bestrahlung [...] Tumorlokalisation adressiert ("zum Beispiel Salvage-Prostatektomie trotz Fernmetastasen"). ASV URO A3: High Risk PCA vor kurativ intendierter Therapie (z. B. EBRT oder RPE). – Das PSMA-PET ist sinnvoll

of type 1 diabetes mellitus (T1DM), an autoimmune disease, and of type 2 diabetes mellitus (T2DM), a metabolic disease. Using morphological, biochemical and molecular morphological methods, the new insights [...] diabetes development or after diabetes development to inhibit the complete beta cell loss leading to a restoration of the beta cell function by regaining normoglycaemia in an infiltration-free pancreas. [...] regeneration with and without immune cell infiltration in the pancreatic islets. The LEW.1AR1- iddm rat, a spontaneous T1DM model is well characterized. The autoimmune correlate is represented by severely i

tension, stability and adhesive properties to cells in a spatiotemporally controlled manner. We follow an interdisciplinary approach that is based on a methodological framework combining protein biochemistry [...] signaling pathways. This complex interplay, which results in the generation of forces and movements, plays a key role in almost all dynamic processes of cells including shape, growth, motility, and division. My

of blood cell formation and function with a special focus on genetic cell modification as a new therapeutic modality. Our research groups collaborate to form a portfolio ranging from the generation and

trapping and disposal by neutrophils. Noack A, Gericke B, von Köckritz-Blickwede M, Menze A, Noack S, Gerhauser I, Osten F , Naim HY, Löscher W. Proc Natl Acad Sci U.S.A.; 2018 Oct 08; 115 (41) E9590-E9599. doi: [...] tes, Osten, F ., Weber, N., Wendland, M., Holler, T., Piep, B., Kröhn, S., Teske, J., Bodenschatz, A.K., Devadas, S.B., Menge, K.S., Chatterjee, S., Schwanke, K., Kosanke, M., Montag, J., Thum, T., Zweigerdt [...] Marker Identification in Chemically Defined Suspension Culture. Halloin C, Schwanke K, Löbel W, Franke A, Szepes M, Biswanath S, Wunderlich S, Merkert S, Weber N , Osten F , de la Roche J, Polten F, Wollert

Our group employs a combinatory approach of biochemistry, biophysics, TIRF imaging with purified proteins, genome editing and cell biology to better understand the molecular basis of a number of fundamental