appraisal regarding reasons for acceptable risk in human challenge studies (Präsentation) 35th European Conference on Philosophy of Medicine and Health Care, European Society for Philosophy of Medicine and [...] proposal for processing ethical aspects in health technology assessment in the face of tensions between EBM standards, contract research and limited resources (Vortrag) Forschungskolloquium Centre for Ethics [...] evaluating arguments / Arguing – ethical theories & strategies for arguing (Workshops) Summer School „Good Practice Bioethics“, Institut für Biomedizinische Ethik und Medizingeschichte, Universität Zürich;
Keck J, Stripecke R. “In Vivo Lentiviral Gene Delivery of HLA-DR and Vaccination of Humanized Mice for Improving the Human T and B Cell Immune Reconstitution” Biomedicines . 2021 Aug 5;9(8):961. doi: 10. [...] Lachmann N , Cornu TI, Mussolino C, Schäfer R, Cathomen T. “CRISPR-Cas12a for Highly Efficient and Marker-Free Targeted Integration in Human Pluripotent Stem Cells” Int J Mol Sci . 2024 Jan 12;25(2):985. doi: [...] Lachmann N , Verboom M, Frieling H, Hallensleben M, Martin U. An Improved Protocol for Targeted Differentiation of Primed Human Induced Pluripotent Stem Cells into HLA-G-Expressing Trophoblasts to Enable the
tissues for application in quantitative real-time PCR. Diagn Mol Pathol 2008; 17(2): 101-6 von Falck C, Rodt T, Rosenthal H, Länger F, Goesling T, Knapp WH, Galanski M: (68)Ga-DOTANOC PET/CT for the detection [...] HJ, Gunzer F: Sensitivity to Escherichia coli Nissle 1917 in mice is dependent on environment and genetic background. Int J Exp Pathol 2008; 89(1): 45-54 Bock O, Höftmann J, Theophile K, Hussein K, Wiese [...] KAI1/CD82 is a novel target of estrogen receptor-mediated gene repression and downregulated in primary human breast cancer. Int J Cancer 2008; 123(10): 2239-46 Ciesek S, Helfritz FA, Lehmann U, Becker T, Strassburg
(Wissenschaftler),Institut für Neuroanatomie und Zellbiologie, Medizinische Hochschule Hannover 10/2020-05/2024 Wissenschaftlicher Mitarbeiter, Developmental Neuroepigenetics Lab, Institut für Anatomie und [...] 09/2015-02/2020 Promotionsstudent, Institut für Pharmakologie, Universitätsmedizin der Johannes Gutenberg-Universität Mainz 07/2015-08/2015 Wissenschaftlicher Mitarbeiter, Institute of Reconstructive Neurobiology [...] 2122467120 A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types. Gather F, Ihrig-Biedert
Veröffentlichungen 2024 Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo Abbas N, Haas JA, Xiao K, Fuchs M, Just A, Pich A, Perbellini F, Werlein C , Ius F, Ruhparwar [...] 1093/eurheartj/ehae102. Pulmonary siRNA Delivery with Sophisticated Amphiphilic Poly(Spermine Acrylamides) for the Treatment of Lung Fibrosis Adams F, Zimmermann CM, Baldassi D, Pehl TM, Weingarten P, Kachel I [...] doi: 10.1002/jev2.12447. Integration of Pathological Criteria and Immunohistochemical Evaluation for Invasive Lobular Carcinoma Diagnosis: Recommendations From the European Lobular Breast Cancer Consortium
Celle; Prof. Dr. Hans-Heinrich Kreipe, PD Dr. Jan Hinrich Bräsen, Institut für Pathologie, MHH; Prof. Dr. Andreas Kispert, Institut für Molekularbiologie, MHH; PD Dr. Christoph Daniel, Prof. Dr. Kerstin [...] charakterisierten wir eine t(7;9) in einer Glioblastom-Primärkultur. Aufgrund dieser Daten schlug das Human Gene Nomenclature Committee den Namen Focadhesin und das Gensymbol FOCAD vor. In vitro Assays zeigten [...] bestimmt sowie funktionelle in vitro Analysen durchgeführt. Kooperationen: Prof. Dr. Peter Claus, Institut für Neuroanatomie, MHH; Carina Thomé, Prof. Dr. Wolfgang Wick, DKFZ Heidelberg; Dr. Marc-Steffen
Publikationen Publications of the Institute of Clinical Biochemistry since 2019 and the former Institute for Cellular Chemistry since 2003 sorted by year and first author. Publikationen 2026 Ramón Roth [...] Ruppert T, Wittbrodt J, Bakker H , Buettner FFR (2021). The C-Mannosylome of Human Induced Pluripotent Stem Cells Implies a Role for ADAMTS16 C-Mannosylation in Eye Development. Mol Cell Proteomics. 2021;20:100092 [...] Glage S, Abeln M , Zweigerdt R, Munder A, Viemann D, Ackermann M, Lachmann N (2021). Human iPSC-derived macrophages for efficient Staphylococcus aureus clearance in a murine pulmonary infection model. Blood
grant, the Lachmann lab aims to use human induced pluripotent stem cells (iPSCs) to unravel the ontogeny of human macrophages and to establish new regenerative therapies for pulmonary infections. Below you [...] Prestigious ERC starting grant for the Lachmann Lab Macrophages are unique hematopoietic cells and have seminal functionalities to maintain the function of the human organism. To establish new macrophage-based [...] dem renommierten „ERC Starting Grant“ ausgezeichnet worden. Der Biomediziner ist Mitarbeiter am Institut für Experimentelle Hämatologie und am REBIRTH-Forschungszentrum für translationale und regenerative
conditions for murine, human and iPSC-derived macrophages under the supervision of Mania Ackermann. He then performed his doctoral thesis under supervision of Adrian Schwarzer at the Institute of Experimental [...] received his PhD from Hannover Medical School, Institute of Experimental Hematology in 2012 and became a group leader at the “REBIRTH Research center for translational and regenerative medicine” in 2015 [...] in Biomedicine at the Hannover Medical School (MHH). She performed her doctoral thesis in the Institute for Hematology at MHH and received her PhD in 2021. In February 2022, she joined the group of Prof
127-146. Katzer M: Challenges to Liberal Human Rights. In: Simon Bennett / Éadaoin O’Brien (Hg.): What Future for Human Rights in a Non-Western World? Human Rights Consortium, School of Advanced Study [...] requirements for human challenge studies: a systematic review of reasons. Clinical Pharmacology & Therapeutics 114 (2023), S. 1209-1219. https://doi.org/10.1002/cpt.3054 Katzer M: Rawls's List of Human Rights [...] Dr. phil. Matthias Katzer Wissenschaftlicher Mitarbeiter Institut für Ethik, Geschichte und Philosophie der Medizin OE 5450 Medizinische Hochschule Hannover Carl-Neuberg-Str. 1 D-30625 Hannover Tel.: +49