PD Dr. Nico Lachmann
Dr. Nico Lachmann studied Biomedicine at Hannover Medical School and Yale School of Medicine. He received his PhD from Hannover Medical School, Institute of Experimental Hematology in 2012 and became a group leader at the “REBIRTH Research center for translational and regenerative medicine” in 2015.
The group of Dr. Lachmann combines basic knowledge in hematology with translational approaches using macrophages to develop new cell-based therapies.
Dr. Mania Ackermann studied Biochemistry at the Leibnitz University Hannover and Hannover Medical School (MHH). She was enrolled in the REBIRTH PhD program “Regenerative Sciences” and received her PhD from MHH in 2015. Subsequently, she joined the group of Dr. Lachmann as a postdoctoral fellow. From 2017-2020 she was also a research fellow at the Dana Farber Cancer Institute (DFCI), Harvard Medical School in Boston (cumulative 8 month).
Main research interests: iPSC technology, macrophages, cell-based therapies, hematopoietic development
I studied Molecular Medicine (M.Sc.) at the Medical University of Gottingen and did my master thesis under the supervision of Dr. Nico Lachmann in his laboratory in MHH. In 2016, I started my Ph.D. aiming at large scale production of iPSC derived macrophages under GMP compliant format and evaluating the therapeutic effect of these cells in infectious diseases.
Main research interest: iPSC, macrophages, hematopoietic cells, scalable macrophage production, GMP, infectious diseases
Kathrin Haake studied Molecular Life Science at the Univesity of Lübeck and joined the PhD program "Regenerative Sciences" in 2016 to perform her PhD in the JRG.
Main research interest: iPSC, macrophages, hematopoiesis, primary immunodeficiencies, MSMD
Anna-Lena Neehus studied Biomedicine at the Hannover Medical School. Since 2018 she is working in the "Laboratory of Human Genetics of Infectious Diseases" at the Imagine Institute in Paris in strong collaboration and under the co-supervision of Nico Lachmann.
Main research interests: Primary immunodeficiencies, immunologie, disease modeling, induced pluripotent stem cells
Ariane Nguyen obtained her B. Sc. in Biochemistry from the Leibniz University Hannover and continued her education in Biochemistry at the Hannover Medical School. During her master studies she worked as an research scholar at the Dana-Farber Cancer Institute (Boston/USA) under the supervision of Christian Brendel. Since 2018 she is pursuing her PhD in the laboratory of Nico Lachmann.
Main research interest: (alveolar) macrophages, plasticity, adaptation
Claudio Rodríguez studied a bachellor's degree in Biotechnology at Oviedo University (Spain; 2013-2017). He then studied a master's degree in Molecular Biology at Lund University (Sweden; 2017-2019). He started working on his PhD thesis in 2019, when he was admitted to the Molecular Medicine PhD program at Hannover Medical School (Germany).
Main Research interest: Macrophages, Cystic Fibrosis, Pseudomonas aeruginosa, Mice Models.
Mi-Sun Jang graduated in Molecular Life Science at the University of Hamburg where she received her master’s degree assessing a potential gene therapy approach in a congenital disease in children and is currently enrolled in the Molecular Medicine PhD program at MHH. Since her undergraduate degree she contributed to a number of scientific publications and instructed students in laboratory techniques such as PCR, flow cytometry, cell culture.
Katharina Hahn is a medical student at Hannover Medical School and started her doctoral thesis at the Institute of Experimental Hematology in 2017. She is currently doing a research exchange at the Williams Laboratory, Harvard Medical School, Boston.
Main research interest: Mendelian Susceptibility to Mycobacterial Disease (MSMD), Lentiviral Gene Therapy, Primary Immunodeficiencies, Hematopoietic Stem Cell Gene Therapy, IL-10 Receptor Deficiency
Bachelor and Master Students
Doreen Kloos passed her apprenticeship at Julius-Maximilians-University Würzburg in the Lab of Prof. Dr. Jürgen Schneider Schaulies in 2008. Afterwards she joined the Experimental Hematology at Hannover Medical School, working in the RG Reprogramming & Gene Therapy (Prof. Moritz) and JRG Translational Hematology of Congenital Diseases (PD Dr. Nico Lachmann).
Main interest: culture of huIPSCs, Hematopoetic Differentiation, Lab organization
Theresa Buchegger completed her MTLA education at the Hannover Medical School. Afterwards she joined the group of Nico Lachmann in 2013.
Main research interest: iPSC, macrophages, hematopoietic differentiation
Ingrid Gensch studied biology at the Leibniz University in Hanover and received her bachelor’s degree in 2018. In 2020 she completed her training as a technician.
Main research interest: Differentiation of human iPS-cells to regulatory macrophages.
In 2018 Nihan Kutlu did her A-levels (Abitur) at Gymnasium Bismarckschule in Hannover. She currently takes part in the Voluntary Scientific Year (FWJ) at Hannover Medical School in the lab of Dr. Nico Lachmann.