Translational Hematology

RG Lachmann

Translational Hematology

RG Lachmann

The lab is located on the campus of the Hannover Medical School in Hannover and is a member of the “REBIRTH – Research center for translational and regenerative medicine” as well as the “German Center for Lung Research (DZL)”. The main interest of the lab is to develop new cell-based treatment approaches for rare and common diseases affecting different organs using multipotent and pluripotent stem cells. In addition, the lab aims to combine translational stem cell research with basic biology in order to gain new insights into human hematopoietic development and related disease pathophysiology of congenital diseases. This understanding leads also to the investigation of new ways of blood-cell-farming using scalable hematopoietic differentiation systems.

News

Prestigious ERC starting grant for the Lachmann Lab

More Info

Publication in „Haematologica“

The publication „Ackermann et al. 2020“ shows new insights in the development of human blood stem cells. Ackermann and colleagues used IPSC and organoids to show the formation of blood cells.

More Info

Publication in „Molecular Therapy Methods and Clinial Translation“

The publication „Hahn/Pollmann et al. 2020“ sets the foundation for the first gene therapy of IFNgR1-deficient MSMD. The authors reverse cells from patients with lentiviral vectors.

More Info

Publication in „Cells“

“Haake et al. 2020“ provides insights into the formation of Mendelian Suscpetibility to Mycobacterial Disease. IPSC from patients are established and point out to be important cells for MSMD.

More Info