The lab is located on the campus of the Hannover Medical School in Hannover and is a member of the “REBIRTH – Research center for translational and regenerative medicine” as well as the “German Center for Lung Research (DZL)”. The main interest of the lab is to develop new cell-based treatment approaches for rare and common diseases affecting different organs using multipotent and pluripotent stem cells. In addition, the lab aims to combine translational stem cell research with basic biology in order to gain new insights into human hematopoietic development and related disease pathophysiology of congenital diseases. This understanding leads also to the investigation of new ways of blood-cell-farming using scalable hematopoietic differentiation systems.
News
First MD student defending her MD thesis
We are proud to announce that Jenny Lam, our first MD student, successfully defended her MD thesis on macrophages,ipsc and the disease model for IFNGR1 deficiency! It was published previously in…
Dr. Nico Lachmann is now Professor at MHH. Congrats!:)
We are happy to announce, that our group head is now associate professor (W2) at Hannover Medical School investigating new forms of treatment targeting infections of the lower respiratory tract.
Excellence in Research Award
The American Society for Gene and Cell Therapy (ASGCT) awards the work of Kathrin Haake with an “Excellence in Research” award.
The publication „Ackermann et al. 2020“ shows new insights in the development of human blood stem cells. Ackermann and colleagues used IPSC and organoids to show the formation of blood cells.
Publication in „Molecular Therapy Methods and Clinial Translation“
The publication „Hahn/Pollmann et al. 2020“ sets the foundation for the first gene therapy of IFNgR1-deficient MSMD. The authors reverse cells from patients with lentiviral vectors.
“Haake et al. 2020“ provides insights into the formation of Mendelian Suscpetibility to Mycobacterial Disease. IPSC from patients are established and point out to be important cells for MSMD.
