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Operative Intensive Care Medicine, University Hospital Bonn PD Dr. Heiko Schenk and Prof. Dr. Hermann Haller, Nephrology, Hannover Medical School and Mount Desert Island Biological Laboratory, Maine, USA [...] perform several translational investigations that further elucidate the molecular mechanisms of sepsis (e.g. endothelial dysfunction, glycocalyx injury, dysregulation of immune responses and coagulation) that [...] who might ultimately benefit from ECMO and is trying to improve the way ECMO support is performed (e.g. individualized choice of anticoagulation intensity). We also explore ECMO support in non-traditional

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