Ureterogenese, also der Entwicklung des Harnleiters in der Maus. Dabei geht es vor allem darum, die Gene und die von ihnen kontrollierten Prozesse zu verstehen, die bei angeborenen Defekten des Harnsystems
llen Studie zur Rolle der Proteinkinase-C-alpha in der diabetischen Nephropathie in einem murinen Gen-Knock-out-Modell. Seine pädiatrische Ausbildung begann PD Dr. Böhne 2004 im Rahmen des strukturierten
possibility of working in an international environment with interesting projects on the cutting edge of gene therapy, leukemogenesis and vectorology. Please see scientific goals for additional information. For
2003; 13(2): 133-8 Bock O, Serinsöz E, Neusch M, Schlué J, Kreipe H: The Polycythaemia rubra vera-1 gene is constitutively expressed by bone marrow cells and does not discriminate Polycythaemia vera from [...] Marwedel M, Musholt TJ: Frequency of mutations and loss of heterozygosity of the tumor suppressor gene PTEN in sporadic follicular thyroid carcinomas: does PTEN play a role in carcinogenesis? Langenbecks [...] Kreipe HH, Pfeifer GP, Schlegelberger B, Dammann R: Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma. Oncogene 2003; 22(12): 1866-71 Schultheiss D, Badalyan R, Pilatz A, Gabouev
Ferreira de Figueiredo (Transfusion Medicine) Project: Correction of monogenetic kidney diseases using a gene therapeutic approach Aavani Biju Sindhu INDIA; Sindhu.Aavani @ mh-hannover.de Supervisor: Prof. Dr [...] Felix @ mh-hannover.de Supervisor: Prof. Dr. Axel Schambach (Experimental Hematology) Project: Novel gene therapy strategies for inherited inner ear defects Lena Willmer GERMANY; lena.willmer @ item.fraunhofer
Robert @ mh-hannover.de Supervisor: Prof. Dr. Axel Schambach (Experimental Hematology) Project: Novel gene and immunotherapeutic approaches for the treatment of cervical cancer Pegah Rahmati IRAN Rahmati.Pegah [...] Pegah @ mh-hannover.de Supervisor: Prof. Dr. Britte Eiz-Vesper (Transfusion Medicine) Project: Gene-regulated EBV-specific T cells for personalized adoptive immunotherapy Final exam November 2024 Sonia
Institute of Experimental Hematology Project: Stem and progenitor cells for disease modeling and gene therapy of hearing loss Final exam November 2024 Christian Melcher GERMANY Melcher.Christian @ mh-hannover [...] Axel Schambach, Insitute of Experimental Haematology, Project: Development and validation of novel gene therapeutic approaches for correction of and protection from hearing loss Final exam June 2024 Dimyana
UKE Hamburg (Laufzeit: 1.07.2010 – 31.06.2011) DFG (KFG 123) Teilprojekt 3: Kompartiment-bezogene Gen- und Proteinexpression im Frühstadium der Bronchiolitis obliterans nach Lungentransplantation D. Steinemann [...] Schambach, Michael Ott, Hans R. Schöler, Tobias Cantz für die Arbeit: Generation of Healthy Mice from Gene-Corrected Disease-Specific Induced Pluripotent Stem Cells, erschienen in PLoS Biol 9(7), 2011 2015
Down-regulation of the fetal stem cell factor SOX17 by H33342: a mechanism responsible for differential gene expression in breast cancer side population cells. J Biol Chem 2010; 285(9): 6412-8 Claus RA, Bockmeyer [...] rger B, Göhring G: Telomere shortening and chromosomal instability in myelodysplastic syndromes. Genes Chromosomes Cancer 2010; 49(3): 260-9 Lehmann U : [DNA methylation. From basic research to routine [...] Schlegelberger B, Länger F , Kreipe H , Lehmann U : Epigenetic inactivation of tumour suppressor gene KLF11 in myelodysplastic syndromes. Eur J Haematol 2010; 84(4): 298-303 Reich A, Maj J, Schlue J,
die zugrundeliegende genetische Mutation getroffen werden. Mittlerweile konnten Mutationen in >695 Genen identifiziert werden, die eine genetische Nierenerkrankung auslösen können. In Kooperation mit dem