research during the poster session. New AAV vectors for cardiac-directed gene therapy AAV vectors are promising delivery tools for human gene therapy. However, broad tissue tropism and pre-existing immunity against [...] regulatory elements of hypoxia-sensitive genes in silico predicted the transcription factors SP1 and KLF5 as potential orchestrators in human endothelial hypoxic gene expression. Further studies revealed that [...] Not only did the mouse-specific H19 gene have a therapeutic effect in the mice. Similar effects could also be achieved by the administration of the human H19 gene. "Therefore, we hope that our method

t of cardiovascular research. Copyright Anne Bührke Participation in the 30th European Society of Gene & Cell Therapy (ESGCT) 2023 IMTTS scientists Dr. Anne Bührke and Anita Pralas proudly represented [...] our FIBREX Team at the ESGCT in Brussels. As the ESGCT is a leading organization in the field of gene and cell therapy, we were excited to join this prestigious event and contribute to the exchange of [...] g experience. Especially during the Symposium from the European Innovation Council (EIC) Cell and Gene Therapy community, we gained a lot of new insights and perspectives. Copyright Anita Pralas Participation

J.D. (2023), J Gen Physiol (2023) 155 (11): e202313377, https://doi.org/10.1085/jgp.202313377 , Online ahead of print, PubMed Why make a strong muscle weaker? Iorga B ., Kraft T., J Gen Physiol, . 2021 [...] B. Iorga , Phosphate has dual roles in cross-bridge kinetics in rabbit psoas single myofibrils, J. Gen. Physiol. 2021 Vol. 153 No. 3, DOI: 10.1085/jgp.202012755, PubMed Peter Franz, Vincent Gassl , Andrea

JG, Kreft A, Buesche G, Ganser A, Georgii A: Molecular detection of c-mpl thrombopoietin receptor gene expression in chronic myeloproliferative disorders. Mol Pathol 1999; 52(3): 146-50 Engelking O, Fedorov [...] d immunosuppression in vitro is associated with deregulation of G1 cell cycle control proteins. J Gen Virol 1999; 80(7): 1599-1608 Fieguth A, Kuske M, Debertin AS: Death caused by neglect? Arch Kriminol

n. Schwerpunkte sind die humanen Erreger und deren Diagnostik sowie die translationale Forschung, Gen-/Zelltherapie und das Biosicherheitsmanagement. Das Masterprogramm findet seinen Abschluss im vierten

helfen, das Rätsel um COVID-19 zu lösen. Die Daten soll Aufschluss darüber geben, welche Rolle die Gene, das Immunsystem aber auch Vorerkrankungen wie etwa Diabetes, Asthma, Nierenschäden oder Bluthochdruck

Cardiomyogenic Differentiation and Transdifferentiation By Ectopic Gene Expression - Direct Transition Or Reprogramming Detour? Curr Gene Ther 16, no. 1:14. https://doi.org/10.2174/1566523216666160104141522 [...] Myosin expression and contractile function are altered by replating stem cell-derived cardiomyocytes. J Gen Physiol 155, no. 11. https://doi.org/10.1085/jgp.202313377 . Shum, I. O., Merkert, S., Malysheva, S [...] human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line. Stem Cell Res 64:102918. #authors contributed equally. https://doi.org/10.1016/j

Natalia Ronkina Functional analysis of MK3 using gene targeting approach Seminarraum 1330, 12.00 Uhr 19.5.2006 Prof. Helmut Holtmann Control of inflammatory gene expression by mRNA stabilising mechanisms S [...] Uhr 13.01.2017 Dr. Mark Windheim "How does endosomal signalling control the interleukin-1-induced gene expression?" Gebäude I 3, Ebene 01, R.-Nr. 2020, 12.00 Uhr 16.12.2016 Prof. Dr. Teruko Tamura-Niemann [...] Manuel D. Díaz-Munoz; Babraham Institute, Cambridge, UK "Post-transcriptional mRNA regulation shapes gene expression during the B cell antibody response" Gebäude I 3, Ebene 01, R.-Nr. 2020, 12.00 Uhr 22.01

Science Publishers Link Kirsten Haastert-Talini Editorial for special issue: Gene Therapy approaches for Neuroregeneration Curr Gene Ther 2011 in press (Vol 11 No 2, April 2011) Ratzka A, Baron O, Grothe C [...] hypothesis. Placenta 2007;28(4):353-60. Kirsten Haastert, Claudia Grothe Gene Therapy in Peripheral Nerve Reconstruction Approaches Curr Gene Ther, 2007 Jun, 7:221-228 Grothe C and Timmer M The physiological [...] Hensel, Peter Claus, Hayat Erdem Yurter (2019): Investigations of Microtubule-associated Protein 2 Gene Expression in Spinal Muscular Atrophy. J. Pediatr. Res. 6: 148-154. Bursch F, Kalmbach N, Naujock

alcohol disorders Post mortem studies investigating the tissue-dependent regulation of essential Genes in addiction disorders Scientific Collaborations MHH-internal Cooperation with the Transplantation [...] biochemistry Epigenetics Investigations of alcohol addiction and other physical dependencies Regulation of gene expression in blood and brain Publications: Pubmed Prof. Dr. med. Thomas Hillemacher Medical Director