important drug targets was considered to be a remote idea more than twenty years ago. Meanwhile, the human kinome is known and the spectacular therapeutic results obtained with STI571 (Gleevec) , suggested

lle Hämatologie) Prof. Dr. Lars Dölken (Virologie) Prof. Dr. Nataliya Di Donato (Institut für Humangenetik) Prof. Dr. Anna-Maria Dittrich (Pädiatrische Pneumologie) Prof. Dr. Meike Stiesch (Klinik für

Meyer H, de la Roche J, Thiemann S, Wahl-Schott C, Martin U, Zweigerdt R. Publisher Correction: Human heart-forming organoids recapitulate early heart and foregut development. Nat Biotechnol. 2021 Ju [...] 2020. „Hypertrophic Cardiomyopathy: Prolonged Twitch, Calcium Transients and Action Potentials in Human Stem Cell-Derived Cardiomyocytes with β-Myosin Mutation R723G“. Biophys.J., 2020, 118(3, Suppl.1) [...] U., and Merkert, S. 2019.„Generation of a CFTR knock-in reporter cell line (MHHi006-A-1) from a human induced pluripotent stem cell line”. Stem Cell Res 40, 101542 https://doi.org/10.1016/j.scr.2019.101542

Wilmot tackles racism in its historic origins and contemporary forms. Within the realms of the humanities and civic education, she advocates for decolonial justice, empowerment and a critical diversit [...] After transitioning from academia and research, she supported international and German scientists in human resources development at the University of Cologne. Now, Phuong collaborates with universities and [...] After transitioning from academia and research, she supported international and German scientists in human resources development at the University of Cologne. Now, Phuong collaborates with universities and

furthermore perform patch clamp analyses on human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) to support projects that investigate diverse human cardiac diseases (e.g. Brugada syndrome [...] on-exchangers (ClC-3 through ClC-7). Dysfunction of these anion transport proteins cause diverse human diseases including myotonia, aldosteronism, epilepsy, salt-wasting nephropathies with and without

vivo models, with a particular focus on living myocardial slice. In a translational perspective, human myocardial slices are also extensively used. The multicellular environment and preserved functionality [...] Methodology Myocardial slices (LMS) Myocardial slice preparation and ex vivo culture (mouse, rat, pig, human) Minituarization of LMS for high throughput approaches Isometric force measurement in LMS Calcium [...] and intracellular calcium transients (IonOptix, Coop Prof. T. Kraft, Dr. M. Ricke-Hoch) Models with human induced pluripotent stem cell-derived cardiomyocytes hiPSC-CM differentiation and culture (Coop Dr

Arbeitsgruppe werden zudem verschiedene Protokolle zur Isolierung und Transplantation von murinen und humanen Hepatozyten in Tiermodellen bzw. Xenotransplantationsmodellen entwickelt und optimiert. Die Projekte [...] Arbeitsgruppe werden zudem verschiedene Protokolle zur Isolierung und Transplantation von murinen und humanen Hepatozyten in Tiermodellen bzw. Xenotransplantationsmodellen entwickelt und optimiert. Die Projekte [...] Römermann, Dipl.-Biologin Denise Schlösser, PhD Studentin Josephin Scholz, Assistenzärztin Georgina Schumann, PhD Studentin Dr. rer. nat. Sven Schüngel, PhD-Student 2005 - 2010 Dr. med. Nora Schweitzer, A

Richter R, Eckert K, Henschler R, Wilkens L, Jochheim-Richter A, Aresniev L, Ott M: Human cord blood stem cells generate human cytokeratin 18-negative hepatocyte-like cells in injured mouse liver. Am J Pathol [...] Rudolph KL, Wilkens L: Telomere shortening correlates with increasing aneuploidy of chromosome 8 in human hepatocellular carcinoma. Hepatology 2005; 42(3): 522-6 Preda-Pais A, Stan AC, Casares S, Bona CA [...] Kreipe HH and Pich A: SELDI-MS-based expression profiling of ductal invasive and lobular invasive human breast carcinomas. Pathol Res Pract 2005; 201(12): 763-70 Verhulst A, Asselman M, De Naeyer S, Vervaet

3389/fimmu.2020.592328 In Vivo Lentiviral Gene Delivery of HLA-DR and Vaccination of Humanized Mice for Improving the Human T and B Cell Immune Reconstitution. Kumar S, Koenig J, Schneider A, Wermeling F, [...] Hematopoiesis 2023 CXCL1 confers a survival advantage in Kaposi's sarcoma-associated herpesvirus-infected human endothelial cells through STAT3 phosphorylation Lee M, Lee J, Kang S, Wirth D, Yoo S, Park C, Lee [...] Deficiency Hildegard Büning, Andrew H. Baker, Uta Griesenbach, Terence R. Flotte, and Adrian J. Thrasher HUMAN GENE THERAPY, VOLUME 32, NUMBERS 1 and 2 DOI: 10.1089/hum.2021.29147.hbu Generation of macrophages

Sarikouch, Hannover Medical School, GER Yoji Sato, National Institute of Health Sciences, JP Gerald Schumann, Paul Ehrlich Institut, GER Henrik Semb, Helmholtz Center, GER Joost Sluijter, University Medical