Headline

Subline

  • Titel

A multicenter, randomized, double-blind, placebo-controlled study to demonstrate that digitoxin reduces a composite of overall mortality and hospitalization for worsening heart failure in patients with chronic heart failure and reduced ejection fraction

  • Förderung

Bundesministerium für Bildung und Forschung - BMBF

  • Studienwebseite

DIGIT-HF

  • Projektpartner innerhalb der MHH

Klinik für Kardiologie und Angiologie

ZKS

  • Publikationen

Bavendiek, Udo, Anika Großhennig, Johannes Schwab, Dominik Berliner, Xiaofei Liu, Lars Maier, Thomas Gaspar, Andreas Rieth, Sebastian Philipp, Rainer Hambrecht, Ralf Westenfeld, Thomas Münzel, Sebastian Winkler, Martin Hülsmann, Dirk Westermann, Marja Zdravkovic, Ralf Lichtinghagen, Heiko von der Leyen, Silke Zimmermann, Christian Veltmann, Michael Böhm, Stefan Störk, Armin Koch, and Johann Bauersachs. 2023. “Simple and Safe Digitoxin Dosing in Heart Failure Based on Data from the DIGIT-HF Trial.” Clinical Research in Cardiology. doi: 10.1007/s00392-023-02199-z.

Bavendiek, Udo, Dominik Berliner, Lukas Aguirre Dávila, Johannes Schwab, Lars Maier, Sebastian A. Philipp, Andreas Rieth, Ralf Westenfeld, Christopher Piorkowski, Kristina Weber, Anja Hänselmann, Maximiliane Oldhafer, Sven Schallhorn, Heiko von der Leyen, Christoph Schröder, Christian Veltmann, Stefan Störk, Michael Böhm, Armin Koch, Johann Bauersachs on behalf of the DIGIT-HF Investigators and Committees. 2019. “Rationale and Design of the DIGIT‐HF Trial (DIGitoxin to Improve OuTcomes in Patients with Advanced Chronic Heart Failure): A Randomized, Double‐blind, Placebo‐controlled Study.” European Journal of Heart Failure 21(5):676–84. doi: 10.1002/ejhf.1452.

Großhennig, Anika, and Armin Koch. 2020. “COVID-19 Hits a Trial: Arguments against Hastily Deviating from the Plan.” Contemporary Clinical Trials 98:106155.doi: 10.1016/j.cct.2020.106155.

Aguirre Dávila, Lukas, Kristina Weber, Udo Bavendiek, Johann Bauersachs, Janet Wittes, Salim Yusuf, and Armin Koch. 2019. “Digoxin–Mortality: Randomized vs. Observational Comparison in the DIG Trial.” European Heart Journal 40(40):3336–41. doi: 10.1093/eurheartj/ehz395.