Publikationen von Prof. Dr. Christian Könecke
2023
2022
2021
Peric Z, Peczynski C, Polge E, Kröger N, Sengeloev H, Radujkovic A, Helbig G, Russell N, Bunjes D, Socié G, Potter V, Beelen D, Crawley C, Bloor A, Finke J, Schoemans H, Penack O, Snowden JA, Koenecke C, Basak GW. Influence of pretransplant inflammatory bowel disease on the outcome of allogeneic hematopoietic stem cell transplantation: a matched-pair analysis study from the Transplant Complications Working Party (TCWP) of the EBMT. Bone Marrow Transplant. 2021 Sep 24. doi: 10.1038/s41409-021-01458-9. Epub ahead of print. PMID: 34561559.
Bošnjak B, Odak I, Ritter C, Stahl K, Graalmann T, Steinbrück L, Blasczyk R, Falk CS, Schulz TF, Wedemeyer HH, Cornberg M, Ganser A, Förster R, Koenecke C. Case Report: Convalescent Plasma Therapy Induced Anti-SARS-CoV-2 T Cell Expansion, NK Cell Maturation and Virus Clearance in a B Cell Deficient Patient After CD19 CAR T Cell Therapy. Front Immunol. 2021 Aug 12;12:721738. doi: 10.3389/fimmu.2021.721738. PMID: 34456929; PMCID: PMC8387963.
Liebers N, Duell J, Fitzgerald D, Kerkhoff A, Noerenberg D, Kaebisch E, Acker F, Fuhrmann S, Leng C, Welslau M, Chemnitz J, Middeke JM, Weber T, Holtick U, Trappe R, Pfannes R, Liersch R, Spoer C, Fuxius S, Gebauer N, Caillé L, Geer T, Koenecke C, Keller U, Claus R, Mougiakakos D, Mayer S, Huettmann A, Pott C, Trummer A, Wulf G, Brunnberg U, Bullinger L, Hess G, Mueller-Tidow C, Glass B, Lenz G, Dreger P, Dietrich S. Polatuzumab vedotin as a salvage and bridging treatment in relapsed or refractory large B-cell lymphomas. Blood Adv. 2021 Jul 13;5(13):2707-2716. doi: 10.1182/bloodadvances.2020004155. PMID: 34196677; PMCID: PMC8288676.
Derlin T, Koenecke C, Schultze-Florey C, Ganser A, Bengel FM. CD19-Targeted Immunotherapy Attenuates Vessel Wall Inflammation. JACC Cardiovasc Imaging. 2021 Sep;14(9):1864-1866. doi: 10.1016/j.jcmg.2021.02.025. Epub 2021 Apr 14. PMID: 33865774.
Panagiota V, Meggendorfer M, Kubasch AS, Gabdoulline R, Krönke J, Mies A, Shahswar R, Kandziora C, Klement P, Schiller J, Göhring G, Haferlach C, Ganster C, Shirneshan K, Gutermuth A, Thiede C, Germing U, Schroeder T, Kobbe G, Klesse S, Koenecke C, Schlegelberger B, Kröger N, Haase D, Döhner K, Sperr WR, Valent P, Ganser A, Thol F, Haferlach T, Platzbecker U, Heuser M. Impact of PPM1D mutations in patients with myelodysplastic syndrome and deletion of chromosome 5q. Am J Hematol. 2021 Jun 1;96(6):E207-E210. doi: 10.1002/ajh.26162. Epub 2021 Apr 7. PMID: 33725366.
Schultze-Florey CR, Kuhlmann L, Raha S, Barros-Martins J, Odak I, Tan L, Xiao Y, Ravens S, Hambach L, Venturini L, Stadler M, Eder M, Thol F, Heuser M, Forster R, Ganser A, Prinz I, Koenecke C. Clonal expansion of CD8+ T cells reflects graft-versus-leukemia activity and precedes durable remission following DLI. Blood Adv. 2021 Sep 17:bloodadvances.2020004073. doi: 10.1182/bloodadvances.2020004073. Epub ahead of print. PMID: 34535011.
Dywicki J, Buitrago-Molina LE, Noyan F, Davalos-Misslitz AC, Hupa-Breier KL, Lieber M, Hapke M, Schlue J, Falk CS, Raha S, Prinz I, Koenecke C, Manns MP, Wedemeyer H, Hardtke-Wolenski M, Jaeckel E. The Detrimental Role of Regulatory T Cells in Nonalcoholic Steatohepatitis. Hepatol Commun. 2021 Aug 25. doi: 10.1002/hep4.1807. Epub ahead of print. PMID: 34532981.
Schultze-Florey CR, Chukhno E, Goudeva L, Blasczyk R, Ganser A, Prinz I, Förster R, Koenecke C, Odak I. Distribution of major lymphocyte subsets and memory T-cell subpopulations in healthy adults employing GLP-conforming multicolor flow cytometry. Leukemia. 2021 Jul 21. doi: 10.1038/s41375-021-01348-5. Epub ahead of print. PMID: 34290358.
Tan L, Fichtner AS, Bruni E, Odak I, Sandrock I, Bubke A, Borchers A, Schultze-Florey C, Koenecke C, Förster R, Jarek M, von Kaisenberg C, Schulz A, Chu X, Zhang B, Li Y, Panzer U, Krebs CF, Ravens S, Prinz I. A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood. Sci Immunol. 2021 Apr 23;6(58):eabf0125. doi: 10.1126/sciimmunol.abf0125. PMID: 33893173.
2020
Penack O, Peczynski C, Mohty M, Yakoub-Agha I, Styczynski J, Montoto S, Duarte RF, Kröger N, Schoemans H, Koenecke C, Peric Z, Basak GW. How much has allogeneic stem cell transplant-related mortality improved since the 1980s? A retrospective analysis from the EBMT. Blood Adv. 2020 Dec 22;4(24):6283-6290. doi: 10.1182/bloodadvances.2020003418. PMID: 33351121; PMCID: PMC7756984.
Penack O, Koenecke C. Complications after CD19+ CAR T-Cell Therapy. Cancers (Basel). 2020 Nov 19;12(11):3445. doi: 10.3390/cancers12113445. PMID: 33228221; PMCID: PMC7699604.
Derlin T, Schultze-Florey C, Werner RA, Möhn N, Skripuletz T, David S, Beutel G, Eder M, Ross TL, Bengel FM, Ganser A, Koenecke C. 18F-FDG PET/CT of off-target lymphoid organs in CD19-targeting chimeric antigen receptor T-cell therapy for relapsed or refractory diffuse large B-cell lymphoma. Ann Nucl Med. 2021 Jan;35(1):132-138. doi: 10.1007/s12149-020-01544-w. Epub 2020 Nov 11. PMID: 33174144; PMCID: PMC7796875.
Riesner K, Cordes S, Peczynski C, Kalupa M, Schwarz C, Shi Y, Mertlitz S, Mengwasser J, van der Werf S, Peric Z, Koenecke C, Schoemans H, Duarte RF, Basak GW, Penack O. Reduced Calcium Signaling Is Associated With Severe Graft-Versus-Host Disease: Results From Preclinical Models and From a Prospective EBMT Study. Front Immunol. 2020 Aug 11;11:1983. doi: 10.3389/fimmu.2020.01983. PMID: 32849661; PMCID: PMC7431962.
Shahswar R, Beutel G, Gabdoulline R, Koenecke C, Markel D, Eder M, Stadler M, Gohring G, Schlegelberger B, Trummer A, Krauter J, Thol F, Heuser M. Risk of tumor lysis syndrome in patients with acute myeloid leukemia treated with venetoclax-containing regimens without dose ramp-up. Ann Hematol. 2021 Feb;100(2):595-599. doi: 10.1007/s00277-020-04181-5. Epub 2020 Jul 23. PMID: 32705308; PMCID: PMC7817590.
Odak, I., Barros-Martins, J., Bošnjak, B., Stahl, K., David, S., Wiesner, O., Busch, M., Hoeper, M. M., Pink, I., Welte, T., Cornberg, M., Stoll, M., Goudeva, L., Blasczyk, R., Ganser, A., Prinz, I., Förster, R., Koenecke, C., & Schultze-Florey, C. R. Reappearance of effector T cells is associated with recovery from COVID-19 [published online ahead of print, 2020 Jul 7]. EBioMedicine. 2020;57:102885. doi:10.1016/j.ebiom.2020.102885
Odak I, Depkat-Jakob A, Beck M, Jarek M, Yu Y, Seidler U, David S, Ganser A, Förster R*, Prinz I*, Koenecke C*. Donor-derived IL-17A and IL-17F deficiency triggers Th1 allo-responses and increases gut leakage during acute GVHD. PLoS One. 2020 Apr 6;15(4):e0231222. doi: 10.1371/journal.pone.0231222. eCollection 2020. PubMed PMID: 32251446.
* These authors contributed equally to this work
Stahl K, Schmidt BMW, Hoeper MM, Skripuletz T, Möhn N, Beutel G, Eder M, Welte T, Ganser A, Falk CS, Koenecke C, David S. Extracorporeal cytokine removal in severe CAR-T cell associated cytokine release syndrome. J Crit Care. 2020 Feb 19;57:124-129. doi: 10.1016/j.jcrc.2020.02.010. [Epub ahead of print] PubMed PMID: 32113143.
Chhatwal P, Ebadi E, Thol F, Koenecke C, Beutel G, Ziesing S, Schlüter D, Bange FC, Baier C. Prospective infection surveillance and systematic screening for vancomycin-resistant enterococci in hematologic and oncologic patients - findings of a German tertiary care center. J Glob Antimicrob Resist. 2020 Feb 21. pii: S2213-7165(20)30041-2. doi: 10.1016/j.jgar.2020.02.012. [Epub ahead of print] PubMed PMID: 32092477.
Hülsdünker J, Thomas OS, Haring E, Unger S, Gonzalo Núñez N, Tugues S, Gao Z, Duquesne S, Cywes-Bentley C, Oyardi O, Kirschnek S, Schmitt-Graeff A, Pabst O, Koenecke C, Duyster J, Apostolova P, Blaser MJ, Becher B, Pier GB, Häcker G, Zeiser R. Immunization against poly-N-acetylglucosamine reduces neutrophil activation and GVHD while sparing microbial diversity. Proc Natl Acad Sci U S A. 2019 Sep 16. pii: 201908549. doi: 10.1073/pnas.1908549116. [Epub ahead of print] PubMed PMID: 31527267.
Ruutu T, van der Werf S, van Biezen A, Backman JT, Peczynski C, Kröger N, Mohty M, Nagler A, Montoto S, Langebrake C, Niederwieser D, Peric Z, Koenecke C, Duarte RF, Basak G. Use of busulfan in conditioning for allogeneic hematopoietic stem cell transplantation in adults: a survey by the Transplant Complications Working Party of the EBMT. Bone Marrow Transplant. 2019 Jun 3. doi: 10.1038/s41409-019-0579-0. [Epub ahead of print] PubMed PMID: 31160806.
Kröger N, Eikema DJ, Köster L, Beelen D, de Wreede LC, Finke J, Koenecke C, Niederwieser D, Bornhäuser M, Schoenland S, Potter V, Wolschke C, Maertens J, Theobald M, Kobbe G, Itälä-Remes M, Wulf G, Kahls P, Forcade E, Greinix H, Masszi T, Yakoub-Agha I, Chalandon Y, Robin M; Chronic Malignancies Working Party of the European Society for Blood Marrow Transplantation. Impact of primary disease on outcome after allogeneic stem cell transplantation for transformed secondary acute leukaemia. Br J Haematol. 2019 May;185(4):725-732. doi: 10.1111/bjh.15819. Epub 2019 Feb 28. PubMed PMID: 30820933.
Tan L, Sandrock I, Odak I, Aizenbud Y, Wilharm A, Barros-Martins J, Tabib Y, Borchers A, Amado T, Gangoda L, Herold MJ, Schmidt-Supprian M, Kisielow J, Silva-Santos B, Koenecke C, Hovav AH, Krebs C, Prinz *, Ravens S*. Single-Cell Transcriptomics Identifies the Adaptation of Scart1(+) Vγ6(+) T Cells to Skin Residency as Activated Effector Cells. Cell Rep. 2019 Jun 18;27(12):3657-3671.e4. doi: 10.1016/j.celrep.2019.05.064. PubMed PMID: 31216482.
*equal contribution
Odak I*, Raha S*, Schultze-Florey C, Tavil S, Ravens S, Ganser A, Förster R, Prinz I**, Koenecke C**. Focusing of the regulatory T cell repertoire after allogeneic stem cell transplantation indicates protection from graft-versus-host disease. Haematologica. 2019 Apr 24. pii: haematol.2019.218206. doi: 10.3324/haematol.2019.218206. [Epub ahead of print] PubMed PMID: 31018979.
*equal contribution, ** shared senior authorship
Gödecke V, Schmidt JJ, Bräsen JH, Koenecke C, Haller H., Diagnosis and treatment of kidney involvement in plasma cell diseases : Renal involvement in multiple myeloma and monoclonal gammopathies. Internist (Berl). 2019 Jan 11. doi: 10.1007/s00108-018-0538-7. [Epub ahead of print] Review. German. PubMed PMID: 30635666
2018:
Bak S, Tischer S, Dragon A, Ravens S, Pape L, Koenecke C, Oelke M, Blasczyk R, Maecker-Kolhoff B, Eiz-Vesper B. Selective Effects of mTOR Inhibitor Sirolimus on Naïve and CMV-Specific T Cells Extending Its Applicable Range Beyond Immunosuppression. Front Immunol. 2018 Dec 17;9:2953. doi: 10.3389/fimmu.2018.02953. eCollection 2018. PubMed PMID: 30619313; PubMed Central PMCID: PMC6304429.
Krauter J, Fiedler W, Schlenk RF, Paschka P, Thol F, Lübbert M, Wattad M, Verbeek M, Könecke C, Neuhaus B, Papkalla A, Kebenko M, Janning M, Döhner K, Gaidzik VI, Becker H, Greil C, Reimer P, Götze KS, Döhner H, Ganser A, Heuser M. Phase I/II study on cytarabine and idarubicin combined with escalating doses of clofarabine in newly diagnosed patients with acute myeloid leukaemia and high risk for induction failure (AMLSG 17-10 CIARA trial). Br J Haematol. 2018 Oct;183(2):235-241. doi: 10.1111/bjh.15546. PubMed PMID: 30378121.
Moiseev IS, Tsvetkova T, Aljurf M, Alnounou RM, Bogardt J, Chalandon Y, Drokov MY, Dvirnyk V, Faraci M, Friis LS, Giglio F, Greinix HT, Kornblit BT, Koelper C, Koenecke C, Lewandowski K, Niederwieser D, Passweg JR, Peczynski C, Penack O, Peric Z, Piekarska A, Ronchi PE, Rovo A, Rzepecki P, Scuderi F, Sigrist D, Siitonen SM, Stoelzel F, Sulek K, Tsakiris DA, Wilkowojska U, Duarte RF, Ruutu T, Basak GW. Clinical and morphological practices in the diagnosis of transplant-associated microangiopathy: a study on behalf of Transplant Complications Working Party of the EBMT. Bone Marrow Transplant. 2018 Oct 25. doi: 10.1038/s41409-018-0374-3. [Epub ahead of print] PubMed PMID: 30361500.
Ziegler AK, Abend M, Port M, Dammann E, Homeyer RS, Eder M, Ganser A, Schrem H, Koenecke C. Cumulative dosages of chemotherapy and radiotherapy exposure, and risk of secondary malignancies after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2018 Oct 18. doi: 10.1038/s41409-018-0359-2. [Epub ahead of print] PubMed PMID: 30337701.
Thol F, Gabdoulline R, Liebich A, Klement P, Schiller J, Kandziora C, Hambach L, Stadler M, Koenecke C, Flintrop M, Pankratz M, Wichmann M, Neziri B, Büttner K, Heida B, Klesse S, Chaturvedi A, Kloos A, Göhring G, Schlegelberger B, Gaidzik VI, Bullinger L, Fiedler W, Heim A, Hamwi I, Eder M, Krauter J, Schlenk RF, Paschka P, Döhner K, Döhner H, Ganser A, Heuser M. Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML. Blood. 2018 Oct 18;132(16):1703-1713. doi: 10.1182/blood-2018-02-829911. Epub 2018 Sep 6. PubMed PMID: 30190321.
Lueck C, Stadler M, Koenecke C, Hoeper MM, Dammann E, Schneider A, Kielstein JT, Ganser A, Eder M, Beutel G. Improved short- and long-term outcome of allogeneic stem cell recipients admitted to the intensive care unit: a retrospective longitudinal analysis of 942 patients. Intensive Care Med. 2018 Sep;44(9):1483-1492. doi: 10.1007/s00134-018-5347-x. Epub 2018 Aug 23. PubMed PMID: 30141173.
Schultze-Florey RE, Tischer S, Kuhlmann L, Hundsdoerfer P, Koch A, Anagnostopoulos I, Ravens S, Goudeva L, Schultze-Florey C, Koenecke C, Blasczyk R, Koehl U, Heuft HG, Prinz I, Eiz-Vesper B, Maecker-Kolhoff B. Dissecting Epstein-Barr Virus-Specific T-Cell Responses After Allogeneic EBV-Specific T-Cell Transfer for Central Nervous System Posttransplant Lymphoproliferative Disease. Front Immunol. 2018 Jun 27;9:1475. doi: 10.3389/fimmu.2018.01475. eCollection 2018. PubMed PMID: 29997626; PubMed Central PMCID: PMC6030255
Koenecke C, Krueger A. MicroRNA in T-Cell Development and T-Cell Mediated Acute Graft-Versus-Host Disease. Front Immunol. 2018 May 7;9:992. doi: 10.3389/fimmu.2018.00992. eCollection 2018. Review. PubMed PMID: 29867969; PubMed Central PMCID: PMC5949326
Hammer Q, Rückert T, Borst EM, Dunst J, Haubner A, Durek P, Heinrich F, Gasparoni G, Babic M, Tomic A, Pietra G, Nienen M, Blau IW, Hofmann J, Na IK, Prinz I, Koenecke C, Hemmati P, Babel N, Arnold R, Walter J, Thurley K, Mashreghi MF, Messerle M, Romagnani C. Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells. Nat Immunol. 2018 Apr 9. doi: 10.1038/s41590-018-0082-6. [Epub ahead of print] PubMed PMID: 29632329.
Garderet L, Iacobelli S, Koster L, Goldschmidt H, Johansson JE, Bourhis JH, Krejci M, Leleu X, Potter M, Blaise D, Koenecke C, Peschel C, Radocha J, Metzner B, Lenain P, Schäfer-Eckart K, Pohlreich D, Grasso M, Caillot D, Einsele H, Ladetto M, Schönland S, Kröger N. Outcome of a Salvage Third Autologous Stem Cell Transplantation in Multiple Myeloma. Biol Blood Marrow Transplant. 2018 Feb 3. pii: S1083-8791(18)30052-1. doi: 10.1016/j.bbmt.2018.01.035. [Epub ahead of print] PubMed PMID: 29408334.
Ravens S, Hengst J, Schlapphoff V, Deterding K, Dhingra A, Schultze-Florey C, Koenecke C, Cornberg M, Wedemeyer H, Prinz I. Human γδ T Cell Receptor Repertoires in Peripheral Blood Remain Stable Despite Clearance of Persistent Hepatitis C Virus Infection by Direct-Acting Antiviral Drug Therapy. Front Immunol. 2018 Mar 16;9:510. doi: 10.3389/fimmu.2018.00510. eCollection 2018. PubMed PMID: 29616028; PubMed Central PMCID: PMC5864898.
2017:
Scheid C, de Wreede L, van Biezen A, Koenecke C, Göhring G, Volin L, Maertens J, Finke J, Passweg J, Beelen D, Cornelissen JJ, Itälä-Remes M, Chevallier P, Russell N, Petersen E, Milpied N, Richard Espiga C, Peniket A, Sierra J, Mufti G, Crawley C, Veelken JH, Ljungman P, Cahn JY, Alessandrino EP, de Witte T, Robin M, Kröger N. Validation of the revised IPSS at transplant in patients with myelodysplastic syndrome/transformed acute myelogenous leukemia receiving allogeneic stem cell transplantation: a retrospective analysis of the EBMT chronic malignancies working party. Bone Marrow Transplant. 2017 Sep 11. doi: 10.1038/bmt.2017.171. [Epub ahead of print] PubMed PMID: 28892084.
Ogonek J, Verma K, Schultze-Florey C, Varanasi P, Luther S, Schweier P, Kühnau W, Göhring G, Dammann E, Stadler M, Ganser A, Koehl U, Koenecke C, Weissinger EM, Hambach L. Characterization of High-Avidity Cytomegalovirus-Specific T Cells with Differential Tetramer Binding Coappearing after Allogeneic Stem Cell Transplantation. J Immunol. 2017 Jun 19. pii: ji1601992. doi: 10.4049/jimmunol.1601992. [Epub ahead of print] PubMed PMID: 28630092.
Heuser M, Gabdoulline R, Löffeld P, Dobbernack V, Kreimeyer H, Pankratz M, Flintrop M, Liebich A, Klesse S, Panagiota V, Stadler M, Wichmann M, Shahswar R, Platzbecker U, Thiede C, Schroeder T, Kobbe G, Geffers R, Schlegelberger B, Göhring G, Kreipe HH, Germing U, Ganser A, Kröger N, Koenecke C*, Thol F*. Individual outcome prediction for myelodysplastic syndrome (MDS) and secondary acute myeloid leukemia from MDS after allogeneic hematopoietic cell transplantation. Ann Hematol. 2017 Jun 13. doi: 10.1007/s00277-017-3027-5. [Epub ahead of print] PubMed PMID: 28612220.
*equal contribution
Kröger N, Panagiota V, Badbaran A, Zabelina T, Triviai I, Araujo Cruz MM, Shahswar R, Ayuk F, Gehlhaar M, Wolschke C, Bollin R, Walter C, Dugas M, Wiehlmann L, Lehmann U, Koenecke C, Chaturvedi A, Alchalby H, Stadler M, Eder M, Christopeit M, Göhring G, Koenigsmann M, Schlegelberger B, Kreipe HH, Ganser A, Stocking C, Fehse B, Thol F, Heuser M. Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2017 Apr 4. pii: S1083-8791(17)30385-3. doi: 10.1016/j.bbmt.2017.03.034. [Epub ahead of print] PubMed PMID: 28389256.
Ravens S, Schultze-Florey C, Raha S, Sandrock I, Drenker M, Oberdörfer L, Reinhardt A, Ravens I, Beck M, Geffers R, von Kaisenberg C, Heuser M, Thol F, Ganser A, Förster R, Koenecke C*, Prinz I*. Human γδ T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection. Nat Immunol. 2017 Feb 20. doi: 10.1038/ni.3686. [Epub ahead of print] PubMed PMID: 28218745
*equal contribution
Sethi MK, Thol F, Stadler M, Heuser M, Ganser A, Koenecke C*, Pabst O*. VH1 Family Immunoglobulin Repertoire Sequencing after Allogeneic Hematopoietic Stem Cell Transplantation. PLoS One. 2017 Jan 17;12(1):e0168096. doi: 10.1371/journal.pone.0168096. PubMed PMID: 28095438
*equal contribution
2016:
Weissinger EM, Human C, Metzger J, Hambach L, Wolf D, Greinix HT, Dickinson AM, Mullen W, Jonigk D, Kuzmina Z, Kreipe H, Schweier P, Böhm O, Türüchanow I, Ihlenburg-Schwarz D, Raad J, Durban A, Schiemann M, Könecke C, Diedrich H, Holler E, Beutel G, Krauter J, Ganser A, Stadler M. The proteome pattern cGvHD_MS14 allows early and accurate prediction of chronic GvHD after allogeneic stem cell transplantation. Leukemia. 2016 Sep 28. doi: 10.1038/leu.2016.259. [Epub ahead of print] PubMed PMID: 27677743.
Rausch L, Koenecke C, Koch HF, Kaltenborn A, Emmanouilidis N, Pape L, Lehner F, Arelin V, Baumann U, Schrem H. Matched-pair analysis: identification of factors with independent influence on the development of PTLD after kidney or liver transplantation. Transplant Res. 2016 Aug 2;5:6. doi: 10.1186/s13737-016-0036-1. eCollection 2016. PubMed PMID: 27486513; PubMed Central PMCID: PMC4970231.
Endig J, Buitrago-Molina LE, Marhenke S, Reisinger F, Saborowski A, Schütt J, Limbourg F, Könecke C, Schreder A, Michael A, Misslitz AC, Healy ME, Geffers R, Clavel T, Haller D, Unger K, Finegold M, Weber A, Manns MP, Longerich T, Heikenwälder M, Vogel A. Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development. Cancer Cell. 2016 Jul 27. pii: S1535-6108(16)30269-0. doi: 10.1016/j.ccell.2016.06.009. [Epub ahead of print] PubMed PMID: 27478039
Raha S*, Raud B*, Oberdörfer L, Castro CN, Schreder A, Freitag J, Longerich T, Lochner M, Sparwasser T, Berod L*, Koenecke C*, Prinz I*. Disruption of de novo fatty acid synthesis via acetyl-CoA carboxylase 1 inhibition prevents acute graft-versus-host disease. Eur J Immunol. 2016 Jun 24. doi: 10.1002/eji.201546152. [Epub ahead of print] PubMed PMID: 27338930.
*equal contribution
Koenecke C, Heim D, van Biezen A, Heuser M, Aljurf M, Kyrcz-Krzemien S, Volin L, de Souza CA, Gedde-Dahl T, Sengeloev H, Schanz U, Komarnicki M, Arroyo CH, Tholouli E, Gluckman E, Esquirol A, Yakoub-Agha I, Gürman G, Olavarria E, Kröger N. Outcome of patients with chronic myeloid leukemia and a low-risk score: allogeneic hematopoietic stem cell transplantation in the era of targeted therapy. A report from the EBMT Chronic Malignancies Working Party. Bone Marrow Transplant. 2016 Apr 25. doi: 10.1038/bmt.2016.97. [Epub ahead of print] PubMed PMID: 27111041.
Lee CW, Wohlan K, Dallmann I, Förster R, Ganser A, Krueger A, Scherr M, Eder M, Koenecke C. miR-181a Expression in Donor T Cells Modulates Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation. J Immunol. 2016 Mar 23. pii: 1502152. [Epub ahead of print] PubMed PMID: 27009493.
2015:
Schreder A, Moschovakis GL, Halle S, Schlue J, Lee CW, Schippers A, David S, Bernhardt G, Ganser A, Pabst O, Förster R, Koenecke C. Differential effects of gut-homing molecules CC chemokine receptor 9 and integrin-beta7 during acute GvHD of the liver. Biol Blood Marrow Transplant. 2015 Sep 5. pii: S1083-8791(15)00599-6. doi: 10.1016/j.bbmt.2015.08.038. [Epub ahead of print] PubMed PMID: 26348893.
Heuser M, Meggendorfer M, Cruz MM, Fabisch J, Klesse S, Köhler L, Göhring G, Ganster C, Shirneshan K, Gutermuth A, Cerny-Reiterer S, Krönke J, Panagiota V, Haferlach C, Koenecke C, Platzbecker U, Thiede C, Schroeder T, Kobbe G, Ehrlich S, Stamer K, Döhner K, Valent P, Schlegelberger B, Kroeger N, Ganser A, Haase D, Haferlach T, Thol F. Frequency and prognostic impact of casein kinase 1A1 mutations in MDS patients with deletion of chromosome 5q. Leukemia. 2015 Feb 24. doi: 10.1038/leu.2015.49. [Epub ahead of print] PubMed PMID: 25792355.
Kashani E, Föhse L, Raha S, Sandrock I, Oberdörfer L, Koenecke C, Suerbaum S, Weiss S, Prinz I. A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6(+)CD27(-) subset. Nat Commun. 2015 Mar 13;6:6477. doi: 10.1038/ncomms7477. PubMed PMID: 25765849.
Basak GW, Wiktor-Jedrzejczak W, Labopin M, Schoemans H, Ljungman P, Kobbe G, Beguin Y, Lang P, Koenecke C, Sykora KW, Te Boome L, van Biezen A, van der Werf S, Mohty M, de Witte T, Marsh J, Dreger P, Kröger N, Duarte R, Ruutu T. Allogeneic Hematopoietic Stem Cell Transplantation in Solid Organ Transplant Recipients: A Retrospective, Multicenter Study of the EBMT. Am J Transplant. 2015 Mar;15(3):705-14. doi: 10.1111/ajt.13017. Epub 2015 Feb 3. PubMed PMID: 25648262.
2014:
Thol F, Scherr M, Kirchner A, Shahswar R, Battmer K, Kade S, Chaturvedi A,Koenecke C, Stadler M, Platzbecker U, Thiede C, Schroeder T, Kobbe G, Bug G,Ottmann O, Hofmann W, Kröger N, Fiedler W, Schlenk R, Döhner K, Döhner H, Krauter J, Eder M, Ganser A, Heuser M. Clinical and functional implications of microRNA mutations in a cohort of 935 patients with myelodysplastic syndromes and acute myeloid leukemia. Haematologica. 2014 Dec 31. pii: haematol.2014.120345. [Epub ahead of print] PubMed PMID: 25552704.
Koenecke C, Göhring G, de Wreede LC, van Biezen A, Scheid C, Volin L, Maertens J, Finke J, Schaap N, Robin M, Passweg J, Cornelissen J, Beelen D, Heuser M, de Witte T, Kröger N. Impact of the revised International Prognostic Scoring System cytogenetics and monosomal karyotype on outcome after allogeneic stem cell transplantation for myelodysplastic syndromes and secondary acute myeloid leukemia evolving from myelodysplastic syndromes: a retrospective multicenter study of the European Society of Blood and Marrow Transplantation. Haematologica. 2014 Dec 31. pii: haematol.2014.116715. [Epub ahead of print] PubMed PMID: 25552702.
Robin M, Ruggeri A, Labopin M, Niederwieser D, Tabrizi R, Sanz G, Bourhis J,van Biezen A, Koenecke C, Blaise D, Tischer J, Craddock C, Maillard N, Mohty M,Russel N, Schetelig J, Finke J, Gluckman E, de Witte TM, Rocha V, Kroger N. Comparison of Unrelated Cord Blood and Peripheral Blood Stem Cell Transplantation in Adults with Myelodysplastic Syndrome after Reduced-Intensity Conditioning Regimen: A Collaborative Study from Eurocord and Chronic Malignancies Working Party. Biol Blood Marrow Transplant. 2014 Dec 19. pii: S1083-8791(14)01384-6. doi: 10.1016/j.bbmt.2014.11.675. [Epub ahead of print] PubMed PMID: 25529382.
Heuser M, Schlarmann C, Dobbernack V, Panagiota V, Wiehlmann L, Walter C, Beier F, Ziegler P, Yun H, Kade S, Kirchner A, Huang L, Koenecke C, Eder M, Brümmendorf TH, Dugas M, Ganser A, Thol F. Genetic characterization of acquired aplastic anemia by targeted sequencing. Haematologica. 2014 Jun 6. pii: haematol.2013.101642. [Epub ahead of print] PubMed PMID: 24907358.
Heuser M, Panagiota V, Koenecke C, Fehse B, Alchalby H, Badbaran A, Shahswar R, Stadler M, Eder M, Göhring G, Trummer A, Schroeder T, Kobbe G, Thiede C, Platzbecker U, Schlegelberger B, Kroeger N, Ganser A, Thol F. Low frequency of calreticulin mutations in MDS patients. Leukemia. 2014 May 21. doi: 10.1038/leu.2014.165. [Epub ahead of print] PubMed PMID: 24850292.
Panagiota V, Thol F, Markus B, Fehse B, Alchalby H, Badbaran A, Lehmann U,Koenecke C, Shahswar R, Chaturvedi A, Stadler M, Eder M, Göhring G, Koenigsmann M, Kloos A, Trummer A, Schroeder T, Kobbe G, Thiede C, Platzbecker U,Schlegelberger B, Kreipe HH, Ganser A, Kröger N, Heuser M. Prognostic effect of calreticulin mutations in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation. Leukemia. 2014 Feb 7. doi: 10.1038/leu.2014.66. [Epub ahead of print] PubMed PMID: 24504025.
Koenecke C, Pischke S, Beutel G, Ritter U, Ganser A, Wedemeyer H, Eder M. Hepatitis E virus infection in a hematopoietic stem cell donor. Bone Marrow Transplant. 2013 Sep 23. doi: 10.1038/bmt.2013.148. [Epub ahead of print] PubMed PMID: 24056741.
2013:
2011:
Föhse L, Suffner J, Suhre K, Wahl B, Lindner C, Lee CW, Schmitz S, Haas JD, Lamprecht S, Koenecke C, Bleich A, Hämmerling GJ, Malissen B, Suerbaum S, Förster R, Prinz I. High TCR Diversity ensures optimal Function and Homeostasis of FoxP3+ Regulatory T cells. Eur J Immunol. 2011 Sep 19. doi: 10.1002/eji.201141986. [Epub ahead of print]
2010
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