Molekulare Pathologie der Mukoviszidose

Publikationen

Highlights

VJ segment usage of TCR-Beta repertoire in monozygous cystic fibrosis twins. Fischer S, Stanke F, Tümmler B. Front Immunol 2021;  doi: 10.3389/fimmu.2021.599133

The human respiratory tract microbial community structures in healthy and cystic fibrosis infants.  M.-M. Pust, L. Wiehlmann, C. Davenport, I. Rudolf, A.-M. Dittrich, B. Tümmler. NPJ Biofilms Microbiomes 2020;6(1):61.

Phenotypic and Genomic Comparison of the Two Most Common ExoU-Positive Pseudomonas aeruginosa Clones, PA14 and ST235.
S. Fischer, S. Dethlefsen, J. Klockgether, B. Tümmler. mSystems 2020;5(6):e01007-20. 

Rescue from Pseudomonas aeruginosa Airway Infection via Stem Cell Transplantation. K. Brinkert, S. Hedtfeld, A. Burhop, R. Gastmeier, P. Gad, D. Wedekind, C. Kloth, J. Rothschuh, N. Lachmann, M. Hetzel, A. Chari Jirmo, E. Lopez-Rodriguez, C. Brandenberger, G. Hansen, A. Schambach, M. Ackermann, B. Tümmler, A. Munder.  Mol Ther  2020:S1525-0016(20)30660-2.

Why? -Successful Pseudomonas aeruginosa clones with a focus on clone.  C. Lee, J. Klockgether, S. Fischer, J. Trcek, B. Tümmler, U. Römling. FEMS Microbiol Rev 2020;44:740-762. 

Self-assembled peptide-poloxamine nanoparticles enable in vitro and in vivo genome restoration for cystic fibrosis. S. Guan, A. Munder, S. Hedtfeld, P. Braubach, S. Glage, L. Zhang, S. Lienenklaus, A. Schultze, G. Hasenpusch, W. Garrels, F. Stanke, C. Miskey, S. M. Johler, Y. Kumar, B. Tümmler, C. Rudolph, Z. Ivics, J. Rosenecker.  Nat Nanotechnol 2019;14:287-297. 

Long-Term Microevolution of Pseudomonas aeruginosa Differs between Mildly and Severely Affected Cystic Fibrosis Lungs. J. Klockgether, N. Cramer, S. Fischer, L. Wiehlmann, B. Tümmler.  Am J Respir Cell Mol Biol 2018;59:246-256. 

Effects of Lumacaftor-Ivacaftor Therapy on Cystic Fibrosis Transmembrane Conductance Regulator Function in Phe508del Homozygous Patients with Cystic Fibrosis.  S. Y. Graeber, C. Dopfer, L. Naehrlich, L. Gyulumyan, H. Scheuermann, S. Hirtz, S. Wege, H. Mairbäurl, M. Dorda, R. Hyde, A. Bagheri-Hanson, C. Rueckes-Nilges, S. Fischer, M. A. Mall, B. Tümmler.  Am J Respir Crit Care Med 2018;197:1433-1442. 

 

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