die zugrundeliegende genetische Mutation getroffen werden. Mittlerweile konnten Mutationen in >695 Genen identifiziert werden, die eine genetische Nierenerkrankung auslösen können. In Kooperation mit dem

Robert @ mh-hannover.de Supervisor: Prof. Dr. Axel Schambach (Experimental Hematology) Project: Novel gene and immunotherapeutic approaches for the treatment of cervical cancer Pegah Rahmati IRAN Rahmati.Pegah [...] Pegah @ mh-hannover.de Supervisor: Prof. Dr. Britte Eiz-Vesper (Transfusion Medicine) Project: Gene-regulated EBV-specific T cells for personalized adoptive immunotherapy Final exam November 2024 Sonia

Ferreira de Figueiredo (Transfusion Medicine) Project: Correction of monogenetic kidney diseases using a gene therapeutic approach Aavani Biju Sindhu INDIA; Sindhu.Aavani @ mh-hannover.de Supervisor: Prof. Dr [...] Felix @ mh-hannover.de Supervisor: Prof. Dr. Axel Schambach (Experimental Hematology) Project: Novel gene therapy strategies for inherited inner ear defects Lena Willmer GERMANY; lena.willmer @ item.fraunhofer

UKE Hamburg (Laufzeit: 1.07.2010 – 31.06.2011) DFG (KFG 123) Teilprojekt 3: Kompartiment-bezogene Gen- und Proteinexpression im Frühstadium der Bronchiolitis obliterans nach Lungentransplantation D. Steinemann [...] Schambach, Michael Ott, Hans R. Schöler, Tobias Cantz für die Arbeit: Generation of Healthy Mice from Gene-Corrected Disease-Specific Induced Pluripotent Stem Cells, erschienen in PLoS Biol 9(7), 2011 2015

Institute of Experimental Hematology Project: Stem and progenitor cells for disease modeling and gene therapy of hearing loss Final exam November 2024 Christian Melcher GERMANY Melcher.Christian @ mh-hannover [...] Axel Schambach, Insitute of Experimental Haematology, Project: Development and validation of novel gene therapeutic approaches for correction of and protection from hearing loss Final exam June 2024 Dimyana

Prof. Dr. rer. nat. Hildegard Büning (Experimental Hematology) Project: Advancing AAV vector-based gene therapy strategies to protect auditory neurons and improve hearing restoration Maria del Mar Haro [...] Project: The clinical relevance of copy number variation and transcriptional dysregulation of actin gene loci Marie Sophie Schuster , GERMANY, Schuster.Marie @ mh-hannover.de Supervisor: Prof. Dr. med. Kai

Down-regulation of the fetal stem cell factor SOX17 by H33342: a mechanism responsible for differential gene expression in breast cancer side population cells. J Biol Chem 2010; 285(9): 6412-8 Claus RA, Bockmeyer [...] rger B, Göhring G: Telomere shortening and chromosomal instability in myelodysplastic syndromes. Genes Chromosomes Cancer 2010; 49(3): 260-9 Lehmann U : [DNA methylation. From basic research to routine [...] Schlegelberger B, Länger F , Kreipe H , Lehmann U : Epigenetic inactivation of tumour suppressor gene KLF11 in myelodysplastic syndromes. Eur J Haematol 2010; 84(4): 298-303 Reich A, Maj J, Schlue J,

sowie vom Deutschen Zentrum für Infektionsforschung (DZIF) unterstützt. Das KSHV K15 Protein Das K15 Gen des Virus kodiert ein nicht-strukturelles Membranprotein, welches gewisse Ähnlichkeiten zu den latenten [...] sarcoma-associated herpesvirus vIRF2 protein utilizes an IFN-dependent pathway to regulate viral early gene expression. PLoS Pathogens 2019; 15(5):e1007743 Abere B, Samarina N, Gramolelli S, Rückert J, Gerold [...] inhibitory protein, vFLIP, from the viral genome compromises the activation of STAT1-responsive cellular genes and spindle cell formation in endothelial cells. J. Virol. 2011; 85:10375-88. Pietrek M, Brinkmann

n (je teilnehmender GKV) Single-/Trio- Untersuchungsauftrag inklusive Einwilligungserklärung nach GenDG Bitte beachten Sie die Übersicht zum Patientenpfad sowie die Hinweise zur Anmeldung zu den inter

transplantation enables the opportunity of pre-Tx modification of hepatocytes by technologies such as gene therapy. Unfortunately, the promising results obtained in animal models could not be successfully