AG Zweigerdt Zweigerdt Lab Unter Verwendung humaner pluripotenter Stammzellen (hPSCs) arbeiten wir an Aspekten der Entwicklungsbiologie und der regenerativen Medizin mit Schwerpunkt auf dem Herzen sowie [...] Zell-/Gewebemanipulation Drakhlis L, Devadas SB, Zweigerdt R. Generation of heart-forming organoids from human pluripotent stem cells. Nat Protoc. 2021 Dec;16(12):5652-5672. doi: 10.1038/s41596-021-00629-8. Epub [...] Hegermann J, Nolte L, Meyer H, de la Roche J, Thiemann S, Wahl-Schott C, Martin U, Zweigerdt R. Human heart-forming organoids recapitulate early heart and foregut development. Nat Biotechnol. 2021 Feb

einzelnen Kardiomyozyten aus Gewebeschnitten von HCM-Patienten und herzgesunden Kontrollen und in humanen induzierten pluripotenten Stammzellen. Wir konnten zeigen, dass einzelne Kardiomyozyten stark un [...] Luisa (2023) B.Sc. Biologie, Visualisierung der allelspezifischen Transkription des MYH7 -Gens in humanen Kardiomyozyten, AG Kowalski Publikationen Wissenschaftliche Artikel in Fachzeitschriften 2025 Pa [...] Montag J., Weber N., Kowalski K. , Mayer A.-K., Iorga B., Brunkhorst A., Zweigerdt R., Kraft T., Human pluripotent stem cell-derived cardiomyocytes mimic intercellular heterogeneity as pathomechanism in

genetically variant stem cells in human pluripotent stem cell cultures Halloin, C., Hannover Medical School, Germany Chemically defined cardiomyogenic differentiation of human pluripotent stem cells in bioreactors [...] Network and Institute of Biomaterials and Biomedical Engineering, Toronto, Canada on the topic of Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart. Following the keynote [...] Porcine Model of Myocardial Infarction Giacomelli, E., Leiden University Medical Center, Netherlands Human Stem Cell-Derived Cardiac Fibroblasts Enhance Structural and Functional Cardiomyocyte Maturation in

Leonard @ mh-hannover.de Linus Langer Humanmedizinischer Doktorand in der Klinik für Pneumologie und Infektiologie Langer.Linus @ mh-hannover.de Lena Leiber Humanmedizinischer Doktorandin in der Klinik für P

Linden, Ricklingerstr. 5, 30449 Hannover, project: Regulation of chemokine receptor expression on human eosinophils Final exam on November 7th, 2003 (Dr.rer.nat.) Veit Erpenbeck GERMANY (Dr. med.) supervisor: [...] Sellge GERMANY supervisor: Prof. Dr. Bischoff, Gastroenterology and Hepatology, OE 6810, project: Human intestinal mast cells: versatile cells of the intestinal immune system Final exam on November 7th

successfully derived from a wide range of small and large mammals, including mice, rats, pigs, and human tissue obtained from biopsies or explanted hearts. Notably, multiple slices can be generated from [...] sequencing identifies cell-type-specific effects of sodium-glucose co-transporter 2 inhibitors in human myocardial slices. Eur Heart J. 45(35):3292-3295. https://doi.org/10.1093/eurheartj/ehae472 Abbas [...] A., Fiedler J., Weber N., Thum T. (2024) MiR-21 inhibition results in cardioprotective effects in human heart failure ex vivo. Eur Heart J. 45(22):2016-2018. https://doi.org/10.1093/eurheartj/ehae102 Waleczek

immunomodulatory properties of in vitro generated megakaryocytes and platelets Nils Schumann, GERMANY, Schumann.Nils @ mh-hannover.de Supervisor: Prof. Dr. Halyna Shcherbata (Cell Biochemistry) Project: [...] Christine Falk (Transplant Immunology) Project: The impact of tissue-resident T and NK cells on human end-stage lung diseases and clinical lung transplantation Abdul Rahman , INDIA, Rahman.Abdul @ mh-hannover

S, Coker SF, Kupinski AP, Tripathi V, Foster K, Beard M, Binz T. (2020): Engineering an effective human SNAP-23 cleaving botulinum neurotoxin A variant. Toxins 12 , 804. PubMed-Link Leese C, Bresnahan R [...] characterization of botulinum neurotoxin A substrate binding pockets and their re-engineering for human SNAP-23. J Mol Biol 428 , 372-384. PubMed-Link Pirazzini M, Henke T, Rossetto O, Mahrhold S, Krez [...] Microbiol Immunol 364 , 139-157. Review PubMed-Link Strotmeier J, Willjes G, Binz T, Rummel A (2012): Human synaptotagmin-II is not a high affinity receptor for botulinum neurotoxin B and G: increased therapeutic

logy/ Endocrinology, OE 6819, project: Generation of a functional mouse model with a human immune system and human liver cells for the study of HCV pathogenesis and therapy; study of the functional ability [...] supervisor: Prof. Dr. Ott, Gastroenterology/Hepatology/ Endocrinology, OE 6819, project: Standardised human mesenchymal stem cells for regenerative medicine Final exam June 2010 Natalie Naue GERMANY supervisor:

biowissenschaftlichen Studiengang sowie an Absolventinnen und Absolventen eines Veterinär- oder Humanmedizinstudiums . Derzeit stehen 20 Studienplätze in jedem Studienjahr zur Verfügung, die über ein hochsc [...] Biochemie, Molekularbiologie oder Pharmazie) oder abgeschlossenes Studium der Veterinär- oder Humanmedizin wenn der Abschluss noch nicht erreicht ist(*): mindestens 150 von 180 LP (bzw. 180 von 210 LP) [...] bachelor's degree (e.g. biology, biochemistry, biomedicine), as well as graduates of veterinary or human medicine programs. Currently, 20 study places are available in each academic year, which are allocated