cytomegalovirus functions amenable to efficient genetic analysis, many years ago we cloned the genomes of mouse and human cytomegalovirus as bacterial artificial chromosomes (BAC) in E.coli (Messerle et al., 1997; [...] immediate-early (IE) genes and of the functional and immunological properties of the IE proteins of mouse cytomegalovirus. Following several years as a postdoc and scientific assistant at the universities [...] Čičin-Šain L, Dezeljin M, Messerle M. The M25 gene products are critical for the cytopathic effect of mouse cytomegalovirus. Scientific Reports 2017, 7:e15588. 3. Neuber S, Wagner K, Goldner T, Lischka P,
Hedrich HJ, Bleich A. Quantitative phenotyping of inflammatory bowel disease in the IL-10-deficient mouse by use of noninvasive magnetic resonance imaging. Inflamm Bowel Dis. 2013 Jan;19(1):185-93. doi: 10 [...] H, Petri S. In vivo MRI of intraspinally injected SPIO-labelled human CD34+ cells in a transgenic mouse model of ALS. In Vivo. 2012 Jan-Feb;26(1):31-8. PubMed PMID: 22210713. Lu X, Li N, Shushakova N, Schmitt
associated diseases of the bone marrow spanning from discovery of oncogenes and establishment of mouse models to drug discovery. Our research is driven by the urgent need for better treatments of AML patients
Hedrich HJ, Bleich A . Quantitative phenotyping of inflammatory bowel disease in the IL10-deficient mouse by use of non-invasive magnetic resonance imaging. Inflamm Bowel Dis, 19,185-93. Büchler G, Wos-Oxley [...] Schölmerich J, Falk W, Hofmann C, Obermeier F. CpG motifs of bacterial DNA exert protective effects in mouse models of IBD by antigen-independent tolerance induction. Gastroenterology, 136:278-287, 2009. Reviews
in der Medizin Online-Präsenz ORCID: 0000-0001-9715-1582 Ausgewählte Publikationen ZFP982 confers mouse embryonic stem cell characteristics by regulating expression of Nanog, Zfp42, and Dppa3. Dehghanian [...] 1016/j.bbamcr.2024.119686 Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome. Akol I, Izzo A, Gather F, Strack S, Heidrich S, Ó hAilín D,
Society for Neuroscience, 43(29), 5290–5304. https://doi.org/10.1523/JNEUROSCI.1824-22.2023 Denervated mouse CA1 pyramidal neurons express homeostatic synaptic plasticity following entorhinal cortex lesion. [...] 3389/fnmol.2023.1148219 All-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells. Lenz, M., Eichler, A., Kruse, P., Muellerleile, J., Deller, T., Jedlicka, P
address basic questions concerning organ and tissue development and cell differentiation using the mouse as model organism and a variety of modern biochemical, molecular genetic, and transgenic methods and
modifications (in particular palmitoylation) cell-matrix adhesion Adeno-associated virus production Mouse models of dementia, behavioral testing for cognition and locomotion TEAM: Saskia Bosdorf, PhD student
S, Messerle M, Arck PC, Brune W, Renné T. Laboratory diagnostics of murine blood for detection of mouse cytomegalovirus (MCMV)-induced hepatitis. Sci Rep. 2018 Oct 4;8(1):14823. Lueder Y, Heller K, Ritter [...] Ritter C, Keyser KA, Wagner K, Liu X, Messerle M, Stahl FR*, Halle S*, Förster R*. Control of primary mouse cytomegalovirus infection in lung nodular inflammatory foci by cooperation of interferon-gamma expressing
metaplasticity in mouse dentate granule cells. Lenz M, Eichler A, Kruse P, Muellerleile J, Deller T, Jedlicka P, Vlachos A. Elife. 2021 Nov 1;10:e71983. doi: 10.7554/eLife.71983. Denervated mouse CA1 pyramidal