Skalierung, sowie die Datenanalyse, einschließlich Clustering, differenzieller Genexpressionsanalyse und Gene Enrichment Analyse, durch. Der Workflow generiert einen Report im HTML-Format und enthält diverse [...] ng Transcriptomics können ab sofort Datenanalyse-Zeiten für die Programme Qlucore Omics Explorer, GeneSpring GX und Ingenuity Pathway Analysis per Outlook gebucht und genutzt werden. Für nähere Informationen
during the poster session. New AAV vectors for cardiac-directed gene therapy July 2022 AAV vectors are promising delivery tools for human gene therapy. However, broad tissue tropism and pre-existing immunity [...] regulatory elements of hypoxia-sensitive genes in silico predicted the transcription factors SP1 and KLF5 as potential orchestrators in human endothelial hypoxic gene expression. Further studies revealed that [...] Gary Ruvkun, for their “groundbreaking discovery” of microRNA and its role in post-transcriptional gene regulation. It all began with a small worm, C. elegans, which despite its small size of around 1mm
Transplant Engineering at the same institute. Professor Figueiredo is highly interested in cell and gene therapeutic approaches in the field of transfusion and transplantation. She has a long-term expertise
Zelle in das Programm aufgenommen und um Transkriptom-Analysen zu ermöglichen, haben wir uns für PaxGene-Tubes entschieden, in denen man RNA hochstandardisiert lagern kann. Außerdem nehmen wir Abstriche
Pieper DH, Schlüter D (2019). Diversity of bacteria exhibiting bile acid-inducible 7α-dehydroxylation genes in the human gut. Comput Struct Biotechnol J. 17:1016-19. Vasapolli R, Schütte K, Schulz C, Vital
Pieper, Schlüter D (2019) Diversity of bacteria exhibiting bile acid-inducible 7α-dehydroxylation genes in the human gut. Comput. Struct. Biotechnol. J. 17:1016-1019. doi 10.1016/j.csbj.2019.07.012.
Hematology, project: Development of a novel alpharetroviral vector system for hematopoietic stem cell gene therapy in Wiskott Aldrich Syndrome Final exam November 2014. Sebastian Goy GERMANY supervisor: Dr
Kosanke, M., Montag, J., Thum, T., Zweigerdt, R., Kraft, T., Iorga, B., and Meissner, J.D. (2023), J Gen Physiol (2023) 155 (11): e202313377, https://doi.org/10.1085/jgp.202313377 , Online ahead of print
Funding (Selection): CardioReGenix : Development of Next-Generation Gene Therapies for Cardiovascular Disease Duration: January 1, 2019 – June 30, 2024 TRAIN-HEART : RNA therapeutics for heart failure
nih.gov/pubmed/30785826 (Apr 2019) Unsere Arbeit zu HER2 Mutationen im lobulären Karzinom ist in Genes Chromosomes and Cancer erschienen: www.ncbi.nlm.nih.gov/pubmed/30520184 (Jan 2019) Die AG klinische [...] nih.gov/36347887/ ( Nov. 2022) Together with the West German Study Group (WSG) we have characterized gene expression pattern in breast cancers under anti-HER2 therapy with trastuzumab/pertuzumab. The results [...] German Study Group (WSG) we have conducted the first clinical trial worldwide, that has combined a gene expression-based assay (Oncotype DX Recurrence Score) with Ki67-response evaluation after pre-operative