RNA-based Therapeutics RNA molecules play a critical role in a wide range of biological processes, including the initiation and progression of diseases. As a result, RNA-based therapeutics have emerge

Organ Fibrosis Organ fibrosis is a pathological condition characterized by the abnormal increase of connective tissue and excessive accumulation of extracellular matrix components, particularly collag

Lipid Nanoparticles RNA therapeutics are rapidly emerging as a key therapeutic modality. However, a major challenge for broader application remains their specific delivery to target tissues and cells,

PROTACs Classical pharmacological inhibitors can only target a small subset of proteins mainly catalytically active enzymes. Therefore, the vast majority of the proteome remains undruggable including

Superparamagnetic Nanoparticles The therapeutic potential of superparamagnetic nanoparticles has attracted great scientific interest. So far, research has been devoted to the concept of magnetic hyper

Disease Modeling Recreating diseases in a dish Disease modeling using human induced pluripotent stem cells (hiPSCs) is a powerful and evolving approach in biomedical research. Patient- or donor-derive

Heart Failure & Remodeling Heart failure is a complex clinical syndrome with a multifaceted pathophysiology. It is a severe condition resulting from ventricular dysfunction, and its prevalence is incr

Safety & Drug Testing The cardiovascular system is regulated by a complex interplay of pressure dynamics, neurological signals, chemical compounds and other physiological factors. Consequently, treatm