F-actin Biochemistry , 39 , 4527-4532. ( Abstract ) ( pdf ) Furch, M., Remmel, B., Geeves, M.A. & Manstein, D.J. (2000) Stabilization of the actomyosin complex by negative charges on myosin Biochemistry 39 [...] Biphenyl compounds for use in treating malaria and other parasitic disorders. US9499471 B2 , published on 22. Nov. 2016 Manstein, D.J., Preller, M., Kalesse, M. Novel means and methods for treating malaria [...] g peroxidase from Dictyostelium discoideum. International Journal of Molecular Sciences. Accepted for publication. Pertici, I., Taft, M.H., Greve, J.N., Fedorov, R., Caremani, M., Manstein, D.J. (2021)
clinical fellow in Neurology at the Uniklinikum Jena, she worked as a postdoctoral fellow in the Center for Immunology and Inflammatory Diseases at the Massachusetts General Hospital & the Harvard Medical [...] Paul @ mh-hannover.de Tel: 9738 Paul Neuhof is a PhD candidate within the HBRS program and the center for infection biology (ZIB), studying neuropeptide influence on innate immune cells. His project focuses
available for medical doctors. As to clinical training: Depending on the clinical subject, we have several role models. Rotation models are also available. Part of your PhD time can be accepted for the "F [...] clinical training after Staatsexamen for 1-3 years. Then they interrupt their training (after e.g. the common trunk, first diagnostic training), then do their PhD for 3-4 years (fulltime) and after that [...] credits for "Facharztweiterbildung". However, please note that this model depends on the respective department and funding, because it is most feasible if you continue with a full-time position for the PhD
Muenchen, German Research Center for Environmental Health, Neuherberg, 1998 - 2001 PostDoc, Institute of Epidemiology, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg [...] focussing on cardio-metabolic diseases (DIAGRAM ands MAGIC for type 2 diabetes; IBC 50K CAD consortium, Global BPgen Consortium, CARDIoGRAM Consortium for cardiovascular diseases). In Munich Thomas Illig was [...] 12/2011 Head of Research Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Since 2009 Head of Biomaterials group of the German National
Schiavo G, Mavlyutov T, Henke T, Binz T, Davletov B. (2020): Duplication of clostridial binding domains for enhanced macromolecular delivery into neurons. Toxicon X 5 :100019. PubMed-Link Sikorra S, Skiba M [...] and characterization of botulinum neurotoxin A substrate binding pockets and their re-engineering for human SNAP-23. J Mol Biol 428 , 372-384. PubMed-Link Pirazzini M, Henke T, Rossetto O, Mahrhold S, [...] a mode similar to that of serotype B: tyrosine 1186 and lysine 1191 cause its lower affinity. Biochemistry 52 , 3930-3938. PubMed-Link Mahrhold S, Strotmeier J, Garcia-Rodriguez C, Lou J, Marks, JD, Rummel
Delegation des National Cancer Center Indonesiens besucht Krebszentrum der MHH Absichtserklärung zur Verbesserung der Qualität der Gesundheitsversorgung und Forschung in der Onkologie unterzeichnet. Die [...] Delegation des indonesischen Gesundheitsministeriums hat am 31. Mai 2022 das Comprehensive Cancer Center (CCC) der Medizinischen Hochschule Hannover (MHH) besucht. Darunter Professor Dr. Abdul Kadir, G [...] Gesundheitsdienste des Gesundheitsministeriums und Dr. Soeko Werdi Nindito, Direktor des National Cancer Center Dharmais in Indonesien. Beim gemeinsamen Treffen haben die Krebszentren eine Absichtserklärung zur
Hilfiker-Kleiner (Cardiology) Project: Immunoregulatory functions of the serotonin receptor 5-HT7 for myocardial remodeling in response to myocardial infarction Final exam November 2024 Sinje Biß GERMANY [...] Günzel GERMANY Guenzel.Steffen @ mh-hannover.de Supervisor: Prof. Dr. Halyna Shcherbata, Cell Biochemistry Project: Role of major non-integrin ECM receptor Dystroglycan Funmilola Haukamp GERMANY Haukamp [...] (IMTTS) Project: Screening and validation of natural compound libraries in human iPSC-cardiomyocytes for the treatment of Fabry disease Final exam June 2024 Bushra Khan INDIA khan.bushra @ mh-hannover.de
of the resistance mechanism for ecophysiology of multidrug-resistant Enterobacteriaceae and their interplay with gut microbiota Supervisor: PD Dr. Marius Vital, Institute for Medical Microbiology and Hospital [...] Georgiev, Institute of Immunology, MHH Academic Background: Biochemistry, MHH Imke Hinrichs Research Topic: Immunological niches as distinct target for novel monoclonal antibodies Supervisor: Dr. Yannic Bartsch [...] immunmodulatory treatment of ARDS of different origin Supervisor: Dr. Theresa Graalmann, Institute for Experimental Infection Research, AG Translationale Immunology, Twincore Akademic Background: Molecular
cellular functions and for biomedical applications. In particular, the link between allostery and catalysis in biological systems is highly relevant for the development of new drugs and biotechnology. We studied [...] which are essential for ribosome assembly and catalytic function, were revealed. These data contributed to an understanding of the translation mechanism (see the background information for the Nobel Prize [...] metabolism. In pathogen Leishmania major UGP (LmUGP) generates the NDP-pools for glycocalyx formation, which is essential for infectivity. In our work, we discovered a previously unknown specific allosteric
research. Accordingly, he played a key role in founding the German Center for Infection Research (DZIF), serving for many years as spokesperson for the “TTU Hepatitis” unit. Under his leadership, crucial advances [...] but still new in infectiology. By founding the Center for Individualized Infection Medicine (CiiM), where he was founding director, he laid the foundation for this new field. His legacy at CiiM continues [...] atmosphere that encouraged creativity and scientific thinking. For these reasons and more, our department has been the most research-intensive at MHH for many years, measured by publication output and third-party